The VICC.ORG Directory of Cancers: Treatments, Services & Resources

Gastrointestinal Cancers

The Gastrointestinal (GI) Oncology Program focuses on malignancies of the esophagus, stomach, small intestine, colon, rectum, anus, liver, gallbladder, pancreas and bile ducts.


Clinical Trials for Gastrointestinal Cancers

23 Open Trials

Trial Type &
Disease
Protocol No. &
Open Date
Summary
Basic Science
Esophageal
VICCGI1012
03/05/2010
Foregut Mircobiome in Development of Esophageal Adenocarcinoma (Clinical Sampling Protocol)
Diagnostic
Liver
VICCGI1343
02/06/2014
Multi-Parametric 3 Tesla Magnetic Resonance Imaging (MRI) of Response to Transarterial Chemoembolization (TACE) in Patients with Hepatocellular Carcinoma (HCC)
DiagnosticVICCGI0283
06/01/2002
Novel Gastrointestinal Cancer Markers in Tissue and Biofluids
Other
Colon;
Rectal
VICCGI0721
01/09/2007
Vanderbilt Hereditary Colorectal Cancer Registry
Other
Liver;
Neuroendocrine
VICCGI0372
10/01/2003
Outcomes Following Image-Guided Therapy for Hepatic Malignancies.
Prevention
Colon
GIS0820-M
07/09/2013
A double blind placebo controlled trial of eflornithine and sulindac to prevent recurrence of high risk adenomas and second primary colon ca in patients with stage 0-III colon ca; phase III - Preventing Adenomas of the Colon with Eflornithine and Sulindac
Supportive Care
Breast;
Colon;
Lung;
Prostate;
Rectal
VICCREACH1341
09/05/2013
Using a Tailored Navigation Intervention to Prepare Patients and Their Support Person for the Journey at Time of Cancer Diagnosis and at Transition into Survivorship
Treatment
Esophageal;
Gastric/Gastroesophageal;
Lung;
Non Small Cell;
Pancreatic
VICCPHI1360
04/22/2014
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5745 as Monotherapy and in Combination with Chemotherapy in Subjects with Advanced Solid Tumors
Treatment
Breast;
Colon;
Lung;
Ovarian;
Pancreatic;
Prostate;
Rectal
VICCPHI1394
04/17/2014
A Phase I/II Study of IMMU-132 (hRS7-SN38 Antibody Drug Conjugate) in Patients with Epithelial Cancer
Treatment
Colon;
Esophageal;
Pancreatic
VICCBMT1381
01/23/2014
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Safety and Efficacy of Orbec? (Oral Beclomethasone 17,21-Dipropionate) Administered as Monotherapy in the Treatment of Upper Gastrointestinal (GI) Symptoms Caused by Graft vs Host Disease (GVHD) in Patients with Chronic GI GVHD
Treatment
Pancreatic
VICCGI1370
12/30/2013
A Phase 1b Dose Escalation Study of Vantictumab (OMP-18R5) in Combination with Nab-Paclitaxel and Gemcitabine in Patients with Previously Untreated Stage IV Pancreatic Cancer
Treatment
Breast;
Gastric/Gastroesophageal;
Lung;
Pancreatic
VICCPHI1359
12/03/2013
A Phase 1/2, Open-label Study of Nivolumab Monotherapy or Nivolumab combined with Ipilimumab in Subjects with Advanced or Metastatic Solid Tumors
Treatment
Colon;
Rectal
ECOGGIS0820
09/03/2013
A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients with Stage 0-III Colon Cancer, Phase III - Preventing Adenomas of the Colon with Eflornithine and Sulindac (PACES)
Treatment
Esophageal;
Gastric/Gastroesophageal
VICCGI1306
07/11/2013
Randomized, Open Label, Phase 2 Study of MM-111 and Paclitaxel with Trastuzumab in Patients with HER2 Positive Carinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach Who Have Failed Front Line Metastatic or Locally Advanced Therapy
Treatment
Colon;
Rectum
VICCPHI1314
06/25/2013
A Phase I/II Study of Once or Twice Weekly IMMU-130 (hMN-14- SN38, Antibody-Drug Conjugate) in Patients with Colorectal Cancer
Treatment
Neuroendocrine;
Pancreatic
VICCGI1250
04/09/2013
A Phase I/II Study of the Combination of Temozolomide and Pazopanib in Advanced Pancreatic Neuroendocrine Tumors (PNET)
Treatment
Pancreatic
ECOGGIS1115
03/21/2013
Randomized Phase II Clinical Trial of AZD6244 Hydrogen Sulfate (NSC-748727) and MK-2206 (NSC-749607) vs. mFOLFOX in Patients with Metastatic Pancreatic Cancer after Prior Chemotherapy
Treatment
Gastric/Gastroesophageal
VICCGI1283
02/14/2013
A Randomized, Multicenter, Adaptive Phase II/III Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine (T-DM1) Versus Taxane (Docetaxel or Paclitaxel) in Patients with Previously Treated Locally Advanced or Metastatic HER2-Positive Gastric Cancer, Including Adenocarcinoma of the Gastroesophageal Junction
Treatment
Pancreatic
VICCGI1173
07/31/2012
A Phase 1 Study of Gemcitabine, Dasatinib and Erlotinib in Patients with Advanced Pancreatic Carcinoma
Treatment
Adrenocortical;
Bladder;
Breast;
Cervical;
Colon;
Dermatologic;
Esophageal;
GIST;
Gastric/Gastroesophageal;
Gynecologic;
Head/Neck;
Kidney (Renal Cell);
Liver;
Lung;
Multiple Myeloma;
Neuroendocrine;
Ovarian;
Pancreatic;
Prostate;
Rectal;
Sarcoma;
Small Cell;
Uterine
VICCMD1188
06/08/2012
An Open-Label, Phase II Study of Vemurafenib in Patients with BRAF V600 Mutation-Positive Cancers
Treatment
Liver
CTSUGI80702-M
05/05/2011
A Phase III Trial of 6 versus 12 Treatments of Adjuvant FOLFOX plus Celecoxib or placebo for patients with Resected Stage III Colon Cancer
Treatment
Liver
CTSUGIC80802-M
12/07/2010
Phase III randomized study of sorafenib (IND 69896, NSC 724772) plus doxorubicin versus sorafenib in patients with advanced hepatocellular carcinoma (HCC)
Treatment
GIST
VICCPHI0958
02/05/2010
A Phase 1 Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of PLX3397 in Patients with Advanced, Incurable, Solid Tumors in which the Target Kinases Are Linked to Disease Pathophysiology

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