The VICC.ORG Directory of Cancers: Treatments, Services & Resources

Lung and Thoracic Cancers


Clinical Trials for Lung Cancers

31 Open Trials

Trial Type &
Disease
Protocol No. &
Open Date
Summary
Therapeutic
Lung
VICCTHN1297
02/07/2013
A Single-Arm Phase 2 Study of BMS-936558 in Subjects with Advanced or Metastatic Squamous Cell Non-Small Cell Lung Cancer Who have Received at Least Two Prior Systemic Regimens
Therapeutic
Lung
VICCTHN1281
01/23/2013
An Open-Label Randomized Phase III Trial of BMS-936558 versus Docetaxel in Previously Treated Metastatic Non-squamous Non-small cell Lung Cancer (NSCLC)
Therapeutic
Lung
VICCTHN1262
01/07/2013
An Open-label Randomized Phase III Trial of BMS-936558 versus Docetaxel in Previously Treated Advanced or Metastatic Squamous Cell Non-small Cell Lung Cancer
Therapeutic
Lung;
Small Cell
VICCTHN1189
12/14/2012
Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab plus Etoposide/Platinum versus Etoposide/Platinum in Subjects with Newly Diagnosed Extensive-Stage Disease Small Cell Lung Cancer (ED-SCLC)
Therapeutic
Lung;
Neuroendocrine;
Non Small Cell
VICCGI1229
11/01/2012
A Randomized, Double-Blind, Multicenter, Phase III Study of Everolimus (RAD001) plus Best Supportive Care versus Placebo plus Best Supportive Care in the Treatment of Patients with Advanced NET of GI or Lung Origin -RADIANT-4
Therapeutic
Lung;
Non Small Cell
VICCTHN1242
10/24/2012
A Phase IB, Multi-Center,Open-Label Study of the MTOR Kinase Inhibitor CC-223 in Combination with Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung Cancer
Therapeutic
Lung;
Small Cell
VICCTHN1212
09/12/2012
Randomized Phase II Study of Single Agent OSI-906, an Oral, Small Molecule, Tyrosine Kinase Inhibitor (TKI) of the Insulin Growth Factor-1 Receptor (IGF-1R) Versus Topotecan for the Treatment of Patients with Relapsed Small Cell Lung Cancer (SCLC)
Therapeutic
Lung
VICCTHN1122
08/21/2012
Open label two-stage study of orally administered BKM120 in patients with metastatic non-small cell lung cancer with activated PI3K pathway
Therapeutic
Lung;
Non Small Cell
VICCTHN1123
07/27/2012
A Phase II Study of the Selective BRAF Kinase Inhibitor GSK2118436 in Subjects with Advanced Non-Small Cell Lung Cancer and BRAF. Mutations
Therapeutic
Adrenocortical;
Bladder;
Breast;
Cervical;
Colon;
Dermatologic;
Esophageal;
GIST;
Gastric/Gastroesophageal;
Gynecologic;
Head/Neck;
Kidney (Renal Cell);
Liver;
Lung;
Multiple Myeloma;
Neuroendocrine;
Ovarian;
Pancreatic;
Prostate;
Rectal;
Sarcoma;
Small Cell;
Uterine
VICCMD1188
06/08/2012
An Open-Label, Phase II Study of Vemurafenib in Patients with BRAF V600 Mutation-Positive Cancers
Therapeutic
Non Small Cell
VICCTHO1042
10/11/2011
A Phase 1-2 Trial of MM-121 in Combination with Erlotinib in Three Groups of Patients with Non-Small Cell Lung Cancer
Therapeutic
Non Small Cell
VICCTHO1079
07/27/2011
Phase 3, Randomized, Open-Label Study of the Efficacy and Safety of Crizotinib versus Pemetrexed/Cisplatin or Pemetrexed/Carboplatin in Previously Untreated Patients with Non-Squamous Carcinoma of the Lung Harboring a Translocation or Inversion Event Involving the Anaplastic Lymphoma Kinase (ALK) Gene Locus
Therapeutic
Lung;
Non Small Cell
ECOGTHNE5508
06/29/2011
Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Premetrexed, or Combination of Bevacizumab and Premtrexed following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC
Therapeutic
Non Small Cell
ECOGTHO5508-M
02/09/2011
Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC
Therapeutic
Lung
ECOGTHO4508-M
12/07/2010
Three-Arm Randomized Phase II Study of Carboplatin and Paclitaxel in Combination with Cetuximab, IMC-A12 or Both for Advanced Non-small Cell Lung Cancer Patients WhoWill Not Receive Bevacizumab-based Therapy
Therapeutic
Lung
CTSUTHOC30607-M
02/17/2010
ARandomized, Phase III, Double-Blind Placebo-Controlled Trial of Sunitinib as Maintenance Therapy in Non-Progressing Patients following an Initial Four Cycles of Platinum-Based Combination Chemotherapy in Advanced, Stage IIIB/IV Non-Small Cell Lung Cancer
Therapeutic
Lung;
Non Small Cell
VICCTHO0730
10/15/2007
A Phase II Trial of Celecoxib plus Chemotherapy [Docetaxel or Pemetrexed] in Patients with Previously Treated, "COX Dependent" Recurrent Non-Small Cell Lung Cancer (SPORE)
Therapeutic
Lung;
Non Small Cell
ECOGTHOE1505
08/30/2007
A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients With Completely Resected Stage IB (>=4 cm)-IIIA Non-Small Cell Lung Cancer (NSCLC).
Therapeutic
Non Small Cell
ECOGTHOE1505-M
07/27/2007
A Phase III Randomized Trial of Adjuvant Chemotherapy with or without Bevacizumab for Patients with Completely Resected Stage IB (> or = 4 cm)- IIIA Non-Small Cell Lung Cancer (NSCLC)
Correlative
Lung
VICCTHN1311
04/12/2013
Inherited Genetic Risk Factors Common to Lung Cancer and COPD: (LC-COPD)
Correlative
Lung
VICCTHN1291
03/28/2013
Early Diagnosis of Pulmonary Nodules Using a Plasma Proteomic Classifier
Correlative
Lung
VICCTHN1292
03/18/2013
Validation of Molecular Biomarkers for the Early Detection of Lung Cancer in the Setting of Indeterminate Pulmonary Nodules. (Lung Team Project #2)
Correlative
Lung;
Non Small Cell
VICCTHN1167
03/02/2012
A Prospective Study to Evaluate the Concordance of Tumor-Associated EGFR Mutations Detected in Matched Tumor and Blood Samples in Patients with NSCLC
Correlative
Lung;
Non Small Cell
VICCTHN1164
11/04/2011
Molecular Profiles for Lung Cancer Pathogenesis and Detection
Correlative
Lung
VICCTHO0967
07/27/2010
Lung Cancer Mutation Consortium Protocol
Correlative
Lung;
Non Small Cell
VICCTHO0547
12/19/2005
Molecular Fingerprints in Lung Cancer: Predicting Tumor Response to Therapy (SPORE)
Correlative
Lung
VICCTHO0398
12/04/2003
Molecular Predictors of Lung Cancer Behavior. (SPORE)
Correlative
Lung
VICCTHO0373
05/03/2001
Identification and Validation of Molecular Markers in Lung Cancer (SPORE)
Correlative
Non Small Cell
VICCTHO0136
05/01/2001
Molecular Fingerprinting of Lung Cancer (SPORE)
Screen, Detect, Diagnose
Adrenocortical;
Bladder;
Breast;
Cervical;
Colon;
Dermatologic;
Esophageal;
GIST;
Gastric/Gastroesophageal;
Gynecologic;
Head/Neck;
Kidney (Renal Cell);
Liver;
Lung;
Multiple Myeloma;
Neuroendocrine;
Ovarian;
Pancreatic;
Prostate;
Rectal;
Sarcoma;
Small Cell;
Uterine
VICCMD1286
12/17/2012
Screening Protocol to Detect BRAF V600 Mutation Positive Patients for Enrollment into Clinical Research Studies of Vemurafenib
Screen, Detect, Diagnose
Lung;
Miscellaneous
VICCTHO1078
04/12/2011
Nashville Early Diagnosis Lung Cancer Project

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