Clinical Trial ECOGGIS1115


Randomized Phase II Clinical Trial of AZD6244 Hydrogen Sulfate (NSC-748727) and MK-2206 (NSC-749607) vs. mFOLFOX in Patients with Metastatic Pancreatic Cancer after Prior Chemotherapy

Principal Investigator(s)

Dana Cardin


  • Protocol No. ECOGGIS1115
  • Open Date: 03/21/2013
  • Staging: Phase II
  • Age Group: Adults
  • Scope: National
  • Objective: To assess overall survival in patients with metastatic pancreatic cancer treated with the combination of AZD6244 hydrogen sulfate and MK-2206 compared to those treated with mFOLFOX.
  • Disease Sites: Pancreatic
  • Therapies: Chemotherapy - cytotoxic
  • Drugs: AZD6244; MK-2206; mFOLFOX6
  • Participating Institutions: Vanderbilt University
  • National Clinical Trial ID: NCT01658943
  • Secondary Protocol No: S1115



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