Clinical Trial VICCPED0987
Title
The ADVANCE Trial: A Multicenter Validation Study of Biomarkers of Vincristine Peripheral Neuropathy in Children with Acute Lymphoblastic Leukemia
Principal Investigator(s)
Details
- Protocol No. VICCPED0987
- Open Date: 04/08/2010
- Staging: NA
- Age Group: Children
- Scope: National
- Objective: To examine the correlation between genotype for CYP3A5 and vincristine-induced peripheral neuropathy, pharmacokinetics and efficacy. To examine the correlation between known pharmacogenetic polymorphisms in the vinca alkaloid pharmacologic pathway and vincristine-induced peripheral neuropathy, pharmacokinetics, and efficacy
- Disease Sites: Pediatrics; Leukemia
- Therapies: Correlative
- Drugs: None Specified
- Participating Institutions: Vanderbilt University
- Secondary Protocol No: Not Specified
Description
None Provided.
Eligibility
Not provided. Please call for more information.
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