Vanderbilt-Ingram Cancer Center

None Provided.

Criteria
 DISEASE CHARACTERISTICS:

 • Meets 1 of the following criteria:

 • Known or previously diagnosed lung cancer

 • Suspected lung cancer, including the following:

 • Completely resected stage I lung cancer (with no evidence of metastatic disease) for which patient is at risk for developing secondary disease

 • Suspected of having lung cancer due to clinical symptoms, such as positive sputum cytology, hemoptysis, unresolved pneumonia, persistent cough, and positive x-ray

 • Healthy volunteer

 PATIENT CHARACTERISTICS:

 • WBC ≥ 2,000/mm³ but ≤ 20,000/mm³

 • Platelet count ≥ 50,000/mm³

 • Not pregnant

 • No uncontrolled hypertension (i.e., systolic blood pressure > 200 mm Hg, diastolic blood pressure > 120 mm Hg)

 • No unstable angina

 • No known bleeding disorder

 • No other contraindications for white light bronchoscopic examination

 • No other contraindications for fluorescence examination

 PRIOR CONCURRENT THERAPY:

 • More than 3 months since prior fluorescent photosensitizing agents (hematoporphyrin derivatives)

 • More than 3 months since prior and no concurrent chemopreventative drugs (e.g., tretinoin)

 • More than 6 months since prior ionizing radiation treatment to the chest

 • More than 6 months since prior systemic cytotoxic chemotherapy

 • No concurrent anticoagulant therapy