Clinical Trials for Breast Cancer

34 Open Trials

Trial TypeProtocol No. &
Open Date
Summary
TherapeuticVICCBRE1298
04/19/2013
A Safety and Efficacy Study of Intra-Operative Radiation Therapy (IORT) Using the Xoft? Axxent? eBx System at the Time of Breast Conservation Surgery for Early Stage Breast Cancer
TherapeuticVICCBRE12101
04/04/2013
A Phase Ib Trial of BYL719 (an a-Specific PI3K Inhibitor) in Combination with Endocrine Therapy in Post-Menopausal Patients with Hormone Receptor-Positive Metastatic Breast Cancer
TherapeuticVICCBRE12116
03/25/2013
An Open-Label, Phase I Study of ARN-810 in Postmenopausal Women with Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer
TherapeuticVICCBRE1280
02/07/2013
A Phase III Randomized, Double Blind Placebo Controlled Study of BKM120 with Fulvestrant, in Postmenopausal Women with Hormone Receptor-Positive HER2-Negative Locally Advanced or Metastatic Breast Cancer Which Progressed On or After Aromatase Inhibitor Treatment
TherapeuticVICCBRE1270
11/20/2012
A Phase II, Multi-Center, Open-Label, Neoadjuvant, Randomized Study of Weekly Paclitaxel with or without LCL161 in Patients with Triple Negative Breast Cancer
TherapeuticVICCBRE1220
10/22/2012
A Randomized Multicenter Phase II Neoadjuvant Trial of Lapatinib, Trastuzumab, with or without Endocrine Therapy for 12 weeks vs. 24 weeks in patients with HER2 Overexpressing Breast Cancer
TherapeuticVICCPHI1248
10/12/2012
An Open-Label, Phase I, Dose-Escalation Study Evaluating the Safety and Tolerability of GDC0032 in Patients with Locally Advanced or Metastatic Solid Tumors and in Combination with Endocrine Therapy in Patients with Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
TherapeuticVICCMD1188
06/08/2012
An Open-Label, Phase II Study of Vemurafenib in Patients with BRAF V600 Mutation-Positive Cancers
TherapeuticVICCBRE1202
05/04/2012
A Phase Ib, Open-Label, Dose-Escalation Study of the Safety and Pharmacology of PI3-Kinase Inhibitor GDC-0941 in Combination with Paclitaxel, With and Without Bevacizumab or Trastuzumab, in Patients with Locally Recurrent or Metastatic Breast Cancer
TherapeuticVICCBRE1157
05/01/2012
A Randomized Multicenter, Double-blind, Placebo-Controlled Comparison of Chemotherapy plus Trastuzumab plus Placebo versus Chemotherapy plus Trastuzumab plus Pertuzumab as Adjuvant Therapy in Patients with operable HER2-Positive Primary Breast Cancer
TherapeuticCTSUBRENB-43-M
04/26/2012
A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy
TherapeuticCTSUNSABPBREB-47-M
04/26/2012
A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women with Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer 
TherapeuticCTSUBRENCCTGMA32-M
04/23/2012
A Phase III Randomized Trial of Metformin versus Placebo on Recurrence and Survival in Early Stage Breast Cancer
TherapeuticVICCBRE1172
04/16/2012
A Phase II Double-Blind Placebo-Controlled Randomized Study of GDC-0941 or GDC-0980 with Fulvestrant Versus Fulvestrant in Advanced or Metastatic Breast Cancer in Patients Resistant to Aromatase Inhibitor Therapy
TherapeuticECOGBRES1007
01/10/2012
A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor Positive and Her 2 Neu Negative Breast Cancer with Recurrence Score of 25 or Less.
TherapeuticVICCPHI1142
11/11/2011
A Phase Ib dose-escalation study of the safety and pharmacokinetics of SAR245408 administered in combination with SAR256212 in patients with solid tumor cancers
TherapeuticCTSUBRES1007-M
05/25/2011
Phase III randomized trial of standard adjuvant endocrine therapy +/- chemo in patients with 1-3 positive nodes, hormone receptor positive and Her2 negative breast cancer with recurrence score (RS) of 25 or less
TherapeuticCTSUBREC40603-M
12/07/2010
Randomized Phase II 2 X 2 Factorial Trial Of The Addition Of Carboplatin +/- Bevacizumab To Neoadjuvant Weekly Paclitaxel Followed By Dose-Dense AC In Hormone Receptor-Poor/HER2-Negative Resectable Breast Cancer
TherapeuticVICCBRE0776
03/24/2008
Pre-Surgical Trial of Letrozole in Post-Menopausal Patients with Operable Hormone-Sensitive Breast Cancer (SPORE)
CorrelativeVICCBRE1271
01/09/2013
Observational Pilot Study on MRI and Blood-Based Biomarkers of Chemotherapy-Related Cognitive Impairment
CorrelativeVICCBRE1101
02/28/2011
A Retrospective Evaluation of Clinical Breast MRIs in Patients with Localized Breast Cancer
CorrelativeVICCBRE09108
10/13/2010
PET/CT Evaluation of Treatment Response in Breast Cancer
CorrelativeVICCBRE0767
06/11/2008
Predicting Cardiac Effects of Breast Cancer Therapy
CorrelativeVICCBRE0704
02/21/2007
Developing In-Vivo Models of Human Breast Cancer
CorrelativeVICCBRE03103
01/22/2004
Breast Tissue/Body Fluids Repository (SPORE)
CorrelativeVCCBRE0057
10/27/2000
Nashville Breast Health Study
Epidemiology, Observation, OutcomesVICCBRE0939
06/25/2009
Arthralgia in Women With Early Stage Breast Cancer Taking Aromatase Inhibitors: The Breast Cancer Adjuvant Therapy (BCAT) Longitudinal Cohort Study.
Screen, Detect, DiagnoseVICCBRE1277
01/01/2013
Ultra-High Field (7 Tesla) MRI/MRS Evaluation of Breast Cancer
Screen, Detect, DiagnoseVICCMD1286
12/17/2012
Screening Protocol to Detect BRAF V600 Mutation Positive Patients for Enrollment into Clinical Research Studies of Vemurafenib
Screen, Detect, DiagnoseVICCBRE0588
03/07/2006
MRI Evaluation Of Breast Tumor Growth And Treatment Response (SPORE)
Supportive-Non-TherapeuticECOGBREE2Z04-M
06/11/2008
Quality of LIfe in Younger Breast Cancer Survivors
Supportive-Non-TherapeuticCTSUBREC70301-M
06/11/2007
Quality of Life, Employment and Informal Care Cost Analysis in Women Receiving Adjuvant Chemotherapy for Breast Cancer with 0-3 Positive Axillary Lymph Nodes
Supportive-TherapeuticVICCBRE1301
05/07/2013
Young and Strong: An Education and Supportive Care Intervention Study for Young Women with Breast Cancer
Supportive-TherapeuticVICCBRE1299
01/23/2013
Promoting Adherence to Lymphedema Self Care in Breast Cancer Survivors

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