Vanderbilt-Ingram Cancer Center

Publications

• Muszkat, M, Sofowora, GG, Xie, HG, Wood, AJ, Stein, CM Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor response. Pharmacogenet Genomics, 15(1), 23-8, 2005.
• Sofowora, GG, Singh, I, He, HB, Wood, AJ, Stein, CM Effect of acute transdermal estrogen administration on basal, mental stress and cold pressor-induced sympathetic responses in postmenopausal women. Clin Auton Res, 15(3), 193-9, 2005.
• Muszkat, M, Kurnik, D, Solus, J, Sofowora, GG, Xie, HG, Jiang, L, McMunn, C, Ihrie, P, Harris, JR, Dawson, EP, Williams, SM, Wood, AJ, Michael Stein, C Variation in the alpha2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo. Pharmacogenet Genomics, 15(6), 407-14, 2005.
• Sofowora, GG, Dishy, V, Landau, R, Xie, HG, Prasad, HC, Byrne, DW, Smiley, RM, Kim, RB, Wood, AJ, Stein, CM Alpha 1A-adrenergic receptor polymorphism and vascular response. Clin Pharmacol Ther, 75(6), 539-45, 2004.
• Muszkat, M, Sofowora, GG, Wood, AJ, Stein, CM Alpha2-adrenergic receptor-induced vascular constriction in blacks and whites. Hypertension, 43(1), 31-5, 2004.
• Dishy, V, Landau, R, Sofowora, GG, Xie, HG, Smiley, RM, Kim, RB, Byrne, DW, Wood, AJ, Stein, CM Beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo. Pharmacogenetics, 14(8), 517-22, 2004.
• Xie, HG, Wood, AJ, Kim, RB, Stein, CM, Wilkinson, GR Genetic variability in CYP3A5 and its possible consequences. Pharmacogenomics, 5(3), 243-72, 2004.
• Dishy, V, Harris, PA, Pierce, R, Prasad, HC, Sofowora, G, Bonar, HL, Wood, AJ, Stein, CM Sildenafil does not improve nitric oxide-mediated endothelium-dependent vascular responses in smokers. Br J Clin Pharmacol, 57(2), 209-12, 2004.
• Drazen, J M, Green, M F, Wood, A J "The FDA, Politics and Plan B." The New England Journal of Medicine, 3501565-66, 2004.
• Sofowora, G G, Dishy, V, Muszkat, M, Xie, H G, Kim, R B, Harris, P A, Prasad, H C, Byrne, D W, Nair, U B, Wood, A J J, Stein, C M A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade. Clin Pharmacol Ther, 73(4), 366-71, 2003.
• Haas, DW, Wilkinson, GR, Kuritzkes, DR, Richman, DD, Nicotera, J, Mahon, LF, Sutcliffe, C, Siminski, S, Andersen, J, Coughlin, K, Clayton, EW, Haines, J, Marshak, A, Saag, M, Lawrence, J, Gustavson, J, Anne Bennett, J, Christensen, R, Matula, MA, Wood, AJ, , A multi-investigator/institutional DNA bank for AIDS-related human genetic studies: AACTG Protocol A5128. HIV Clin Trials, 4(5), 287-300, 2003.
• Dishy, Victor, Gupta, Simi, Landau, Ruth, Xie, Hong-Guang, Kim, Richard B, Smiley, Richard M, Byrne, Daniel W, Wood, Alastair J, Stein, C Michael G-protein beta3 subunit 825 C/T polymorphism is associated with weight gain during pregnancy. Pharmacogenetics, 13(4), 241-2, 2003.
• Dishy, Victor, Sofowora, Gbenga G, Imamura, Hitoshi, Nishimi, Yukihide, Xie, Hong-Guang, Wood, Alastair J, Stein, C Michael Nitric oxide production decreases after salt loading but is not related to blood pressure changes or nitric oxide-mediated vascular responses. J Hypertens, 21(1), 153-7, 2003.
• Wood, Alastair J Variability in beta-adrenergic receptor response in the vasculature: Role of receptor polymorphism. J Allergy Clin Immunol, 110(6 Suppl), S318-21, 2002.
• Wood, A J "When increased therapeutic benefit comes at increased cost." The New Encgland Journal of Medicine, 3461819-21, 2002.
• Xie, H G, Dishy, V, Sofowora, G, Kim, R B, Landau, R, Smiley, R M, Zhou, H H, Wood, A J, Harris, P, Stein, C M Arg389Gly beta 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo. Pharmacogenetics, 11(3), 191-7, 2001.
• Stein, C M, Sadeque, A J, Murray, J J, Wandel, C, Kim, R B, Wood, A J Cyclosporine pharmacokinetics and pharmacodynamics in African American and white subjects. Clin Pharmacol Ther, 69(5), 317-23, 2001.
• Stein, C M, Lang, C C, Xie, H G, Wood, A J Hypertension in black people: study of specific genotypes and phenotypes will provide a greater understanding of interindividual and interethnic variability in blood pressure regulation than studies based on race. Pharmacogenetics, 11(2), 95-110, 2001.
• Dickmann, L J, Rettie, A E, Kneller, M B, Kim, R B, Wood, A J, Stein, C M, Wilkinson, G R, Schwarz, U I "Identification and functional characterization of a new CYP2C9 variant (CYP2C9*51) expressed among African Americans." Molecular Pharmacology, 60382-387, 2001.
• Sofowora, G, Dishy, V, Xie, H G, Imamura, H, Nishimi, Y, Morales, C R, Morrow, J D, Kim, R B, Stein, C M, Wood, A J In-vivo effects of Glu298Asp endothelial nitric oxide synthase polymorphism. Pharmacogenetics, 11(9), 809-14, 2001.
• Xie, H G, Kim, R B, Wood, A J, Stein, C M Molecular basis of ethnic differences in drug disposition and response. Annu Rev Pharmacol Toxicol, 41815-50, 2001.
• Dishy, V, Sofowora, G G, Xie, H G, Kim, R B, Byrne, D W, Stein, C M, Wood, A J The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization. N Engl J Med, 345(14), 1030-5, 2001.
• Dishy, V, Sofowora, G, Harris, P A, Kandcer, M, Zhan, F, Wood, A J, Stein, C M The effect of sildenafil on nitric oxide-mediated vasodilation in healthy men. Clin Pharmacol Ther, 70(3), 270-9, 2001.
• Editors of The New England Journal of Medicine "Looking back on the millennium in medicine." The New England Journal of Medicine, 35242-50, 2000.
• Wandel, C, Witte, J S, Hall, J M, Stein, C M, Wood, A J, Wilkinson, G R CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A4*1B5'-promoter region polymorphism. Clin Pharmacol Ther, 68(1), 82-91, 2000.
• Xie, H G, Stein, C M, Kim, R B, Gainer, J V, Sofowora, G, Dishy, V, Brown, N J, Goree, R E, Haines, J L, Wood, A J Human beta2-adrenergic receptor polymorphisms: no association with essential hypertension in black or white Americans. Clin Pharmacol Ther, 67(6), 670-5, 2000.
• Sadeque, A J, Wandel, C, He, H, Shah, S, Wood, A J Increased drug delivery to the brain by P-glycoprotein inhibition. Clin Pharmacol Ther, 68(3), 231-7, 2000.
• Stein, C M, Lang, C C, Singh, I, He, H B, Wood, A J Increased vascular adrenergic vasoconstriction and decreased vasodilation in blacks. Additive mechanisms leading to enhanced vascular reactivity. Hypertension, 36(6), 945-51, 2000.
• Wandel, C, Kim, RB, Guengerich, FP, Wood, AJ Mibefradil is a P-glycoprotein substrate and a potent inhibitor of both P-glycoprotein and CYP3A in vitro. Drug Metab Dispos, 28(8), 895-8, 2000.
• Choo, E F, Leake, B, Wandel, C, Imamura, H, Wood, A J, Wilkinson, G R, Kim, R B Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes. Drug Metab Dispos, 28(6), 655-60, 2000.
• He, H, Sadeque, A, Erve, J C, Wood, A J, Hachey, D L Quantitation of loperamide and N-demethyl-loperamide in human plasma using electrospray ionization with selected reaction ion monitoring liquid chromatography-mass spectrometry. J Chromatogr B Biomed Sci Appl, 744(2), 323-31, 2000.
• Wood, A J "Thrombotic thrombocytopenic purpura and clopidogrel - A need for new approaches to drug safety." New England Journal of Medicine, 3431824-1826, 2000.
• Xie, H G, Stein, C M, Kim, R B, Wilkinson, G R, Flockhart, D A, Wood, A J Allelic, genotypic and phenotypic distributions of S-mephenytoin 4'-hydroxylase (CYP2C19) in healthy Caucasian populations of European descent throughout the world. Pharmacogenetics, 9(5), 539-49, 1999.
• Xie, H G, Kim, R B, Stein, C M, Gainer, J V, Brown, N J, Wood, A J Alpha1A-adrenergic receptor polymorphism: association with ethnicity but not essential hypertension. Pharmacogenetics, 9(5), 651-6, 1999.
• Kinirons, M T, Krivruk, Y, Wilkinson, G R, Wood, A J "Effects of ketoconazole on the erythromycin breath test and the dapsone recovery ratio." British Journal of Clinical Pharmacology, 47223-225, 1999.
• Kinirons, M T, O'Shea, D, Kim, R B, Groopman, J D, Thummel, K E, Wood, A J, Wilkinson, G R Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A. Clin Pharmacol Ther, 66(3), 224-31, 1999.
• Xie, H G, Stein, C M, Kim, R B, Xiao, Z S, He, N, Zhou, H H, Gainer, J V, Brown, N J, Haines, J L, Wood, A J Frequency of functionally important beta-2 adrenoceptor polymorphisms varies markedly among African-American, Caucasian and Chinese individuals. Pharmacogenetics, 9(4), 511-6, 1999.
• Xie, H G, Kim, R B, Stein, C M, Wilkinson, G R, Wood, A J Genetic polymorphism of (S)-mephenytoin 4'-hydroxylation in populations of African descent. Br J Clin Pharmacol, 48(3), 402-8, 1999.
• Caraco, Y, Sheller, J, Wood, A J Impact of ethnic origin and quinidine coadministration on codeine's disposition and pharmacodynamic effects. J Pharmacol Exp Ther, 290(1), 413-22, 1999.
• Stein, C M, Murray, J J, Wood, A J Inhibition of stimulated interleukin-2 production in whole blood: a practical measure of cyclosporine effect. Clin Chem, 45(9), 1477-84, 1999.
• Kim, R B, Wandel, C, Leake, B, Cvetkovic, M, Fromm, M F, Dempsey, P J, Roden, M M, Belas, F, Chaudhary, A K, Roden, D M, Wood, A J, Wilkinson, G R Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein. Pharm Res, 16(3), 408-14, 1999.
• Wandel, C, Kim, R B, Kajiji, S, Guengerich, P, Wilkinson, G R, Wood, A J P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies. Cancer Res, 59(16), 3944-8, 1999.
• Wood A J "The Safety of new Medicines: The importance of asking the right questions." Journal of the American Medical Association, 2811753-1754, 1999.
• Brown, N J, Griffin, M R, Ray, W A, Meredith, S, Beers, M H, Marren, J, Robles, M, Stergachis, A, Wood, A J, Avorn, J A model for improving medication use in home health care patients. J Am Pharm Assoc (Wash), 38(6), 696-702, 1998.
• Choy, A M, Lang, C C, Roden, D M, Robertson, D, Wood, A J, Robertson, R M, Biaggioni, I Abnormalities of the QT interval in primary disorders of autonomic failure. Am Heart J, 136(4 Pt 1), 664-71, 1998.
• Robbins, I M, Cuiper, L L, Stein, C M, Wood, A J, He, H B, Parker, R, Christman, B W Angiotensin II mediates systemic rebound hypertension after cessation of prostacyclin infusion in sheep. J Appl Physiol, 85(2), 731-7, 1998.
• Stein, C M, He, H B, Wood, A J Basal and stimulated sympathetic responses after epinephrine: no evidence of augmented responses. Hypertension, 32(6), 1016-21, 1998.
• Wandel, C, Lang, C C, Cowart, D C, Girard, A F, Bramer, S, Flockhart, D A, Wood, A J Effect of CYP3A inhibition on vesnarinone metabolism in humans. Clin Pharmacol Ther, 63(5), 506-11, 1998.
• Wood, A J Ethnic differences in drug disposition and response. Ther Drug Monit, 20(5), 525-6, 1998.
• Wood, A J, Stein, C M, Woosley, R Making medicines safer--the need for an independent drug safety board. N Engl J Med, 339(25), 1851-4, 1998.
• Stein, C M, Brown, N, Vaughan, D E, Lang, C C, Wood, A J Regulation of local tissue-type plasminogen activator release by endothelium-dependent and endothelium-independent agonists in human vasculature. J Am Coll Cardiol, 32(1), 117-22, 1998.
• He, H, Shay, S D, Caraco, Y, Wood, M, Wood, A J Simultaneous determination of codeine and its seven metabolites in plasma and urine by high-performance liquid chromatography with ultraviolet and electrochemical detection. J Chromatogr B Biomed Sci Appl, 708(1-2), 185-93, 1998.
• Kim, R B, Fromm, M F, Wandel, C, Leake, B, Wood, A J, Roden, D M, Wilkinson, G R The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J Clin Invest, 101(2), 289-94, 1998.
• Lang, C C, Stein, C M, He, H B, Belas, F J, Blair, I A, Wood, M, Wood, A J Blunted blood pressure response to central sympathoinhibition in normotensive blacks: increased importance of nonsympathetic factors in blood pressure maintenance in blacks. Hypertension, 30(2 Pt 1), 157-62, 1997.
• Stein, C M, Brown, N, Carlson, M G, Campbell, P, Wood, A J Coadministration of glyburide and minoxidil, drugs with opposing effects on potassium channels. Clin Pharmacol Ther, 61(6), 662-8, 1997.
• Tateishi, T, Soucek, P, Caraco, Y, Guengerich, F P, Wood, A J Colchicine biotransformation by human liver microsomes. Identification of CYP3A4 as the major isoform responsible for colchicine demethylation. Biochem Pharmacol, 53(1), 111-6, 1997.
• He, H, Stein, C M, Christman, B, Wood, A J Determination of catecholamines in sheep plasma by high-performance liquid chromatography with electrochemical detection: comparison of deoxyepinephrine and 3,4-dihydroxybenzylamine as internal standard. J Chromatogr B Biomed Sci Appl, 701(1), 115-9, 1997.
• Lang, C C, Rayos, G H, Chomsky, D B, Wood, A J, Wilson, J R Effect of sympathoinhibition on exercise performance in patients with heart failure. Circulation, 96(1), 238-45, 1997.
• Stein, C M, Wood, A J, Pincus, T Implementation of multiple outpatient formularies: undesirable effects. Clin Pharmacol Ther, 61(1), 1-7, 1997.
• Stein, C M, Deegan, R, Wood, A J Lack of correlation between arterial and venous beta-adrenergic receptor sensitivity. Hypertension, 29(6), 1273-7, 1997.
• Stein, C M, Nelson, R, He, H B, Wood, M, Wood, A J Norepinephrine release in the human forearm: effects of epinephrine. Hypertension, 30(5), 1078-84, 1997.
• Caraco, Y, Sheller, J, Wood, A J Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects. J Pharmacol Exp Ther, 281(1), 330-6, 1997.
• Lang, C C, Stein, C M, Nelson, R A, He, H B, Belas, F J, Blair, I A, Wood, M, Wood, A J Sympathoinhibitory response to clonidine is blunted in patients with heart failure. Hypertension, 30(3 Pt 1), 392-7, 1997.
• Stein, C M, Lang, C C, Nelson, R, Brown, M, Wood, A J Vasodilation in black Americans: attenuated nitric oxide-mediated responses. Clin Pharmacol Ther, 62(4), 436-43, 1997.
• Lang, C C, Stein, C M, He, H B, Wood, A J Angiotensin converting enzyme inhibition and sympathetic activity in healthy subjects. Clin Pharmacol Ther, 59(6), 668-74, 1996.
• Stein, C M, Kinirons, M T, Pincus, T, Wilkinson, G R, Wood, A J Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. Clin Pharmacol Ther, 59(1), 47-51, 1996.
• Lang, C C, Brown, R M, Kinirons, M T, Deathridge, M A, Guengerich, F P, Kelleher, D, O'Briain, D S, Ghishan, F K, Wood, A J Decreased intestinal CYP3A in celiac disease: reversal after successful gluten-free diet: a potential source of interindividual variability in first-pass drug metabolism. Clin Pharmacol Ther, 59(1), 41-6, 1996.
• Caraco, Y, Wilkinson, G R, Wood, A J Differences between white subjects and Chinese subjects in the in vivo inhibition of cytochrome P450s 2C19, 2D6, and 3A by omeprazole. Clin Pharmacol Ther, 60(4), 396-404, 1996.
• Caraco, Y, Lagerstrom, P O, Wood, A J Ethnic and genetic determinants of omeprazole disposition and effect. Clin Pharmacol Ther, 60(2), 157-67, 1996.
• Tateishi, T, Krivoruk, Y, Ueng, Y F, Wood, A J, Guengerich, F P, Wood, M Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation. Anesth Analg, 82(1), 167-72, 1996.
• Robin, D W, Hasan, S S, Edeki, T, Lichtenstein, M J, Shiavi, R G, Wood, A J Increased baseline sway contributes to increased losses of balance in older people following triazolam. J Am Geriatr Soc, 44(3), 300-4, 1996.
• Caraco, Y, Tateishi, T, Guengerich, F P, Wood, A J Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity. Drug Metab Dispos, 24(7), 761-4, 1996.
• Caraco, Y, Sheller, J, Wood, A J Pharmacogenetic determination of the effects of codeine and prediction of drug interactions. J Pharmacol Exp Ther, 278(3), 1165-74, 1996.
• Kinirons, M T, Lang, C C, He, H B, Ghebreselasie, K, Shay, S, Robin, D W, Wood, A J Triazolam pharmacokinetics and pharmacodynamics in Caucasians and Southern Asians: ethnicity and CYP3A activity. Br J Clin Pharmacol, 41(1), 69-72, 1996.
• Lang, C C, Stein, C M, Brown, R M, Deegan, R, Nelson, R, He, H B, Wood, M, Wood, A J Attenuation of isoproterenol-mediated vasodilatation in blacks. N Engl J Med, 333(3), 155-60, 1995.
• Tateishi, T, Wood, A J, Guengerich, F P, Wood, M Biotransformation of tritiated fentanyl in human liver microsomes. Monitoring metabolism using phenylacetic acid and 2-phenylethanol. Biochem Pharmacol, 50(11), 1921-4, 1995.
• Stein, C M, He, H, Pincus, T, Wood, A J Cyclosporine impairs vasodilation without increased sympathetic activity in humans. Hypertension, 26(4), 705-10, 1995.
• Stein, C M, Nelson, R, Brown, M, He, H, Wood, M, Wood, A J Dietary sodium intake modulates systemic but not forearm norepinephrine release. Clin Pharmacol Ther, 58(4), 425-33, 1995.
• Stein, C M, Nelson, R, Brown, M, Wood, M, Wood, A J Dietary sodium intake modulates vasodilation mediated by nitroprusside but not by methacholine in the human forearm. Hypertension, 25(6), 1220-3, 1995.
• Stein, C M, Nelson, R, Deegan, R, He, H, Wood, M, Wood, A J Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension. J Clin Invest, 96(1), 579-85, 1995.
• Caraco, Y, Tateishi, T, Wood, A J Interethnic difference in omeprazole's inhibition of diazepam metabolism. Clin Pharmacol Ther, 58(1), 62-72, 1995.
• Wood, A J Mechanisms for interethnic differences in antihypertensive drug response. Am J Hypertens, 8(12 Pt 2), 128s, 1995.
• Deegan, R, He, H B, Krivoruk, Y, Wood, A J, Wood, M Regulation of norepinephrine release by beta 2-adrenergic receptors during halothane anesthesia. Anesthesiology, 82(6), 1417-25, 1995.
• Zhou, H H, Wood, A J Stereoselective disposition of carvedilol is determined by CYP2D6. Clin Pharmacol Ther, 57(5), 518-24, 1995.
• Stein, C M, Nelson, R, Deegan, R, He, H, Inagami, T, Frazer, M, Badr, K F, Wood, M, Wood, A J Tachyphylaxis of human forearm vascular responses does not occur rapidly after exposure to isoproterenol. Hypertension, 25(6), 1294-300, 1995.
• Deegan, R, Wood, A J Beta-receptor antagonism does not fully explain esmolol-induced hypotension. Clin Pharmacol Ther, 56(2), 223-8, 1994.
• He, H, Edeki, T I, Wood, A J Determination of low plasma timolol concentrations following topical application of timolol eye drops in humans by high-performance liquid chromatography with electrochemical detection. J Chromatogr B Biomed Appl, 661(2), 351-6, 1994.
• Krivoruk, Y, Kinirons, M T, Wood, A J, Wood, M Metabolism of cytochrome P4503A substrates in vivo administered by the same route: lack of correlation between alfentanil clearance and erythromycin breath test. Clin Pharmacol Ther, 56(6 Pt 1), 608-14, 1994.
• Kinirons, M T, O'Shea, D, Downing, T E, Fitzwilliam, A T, Joellenbeck, L, Groopman, J D, Wilkinson, G R, Wood, A J Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men. Clin Pharmacol Ther, 54(6), 621-9, 1993.
• Stein, M, Deegan, R, He, H, Wood, A J Beta-adrenergic receptor-mediated release of norepinephrine in the human forearm. Clin Pharmacol Ther, 54(1), 58-64, 1993.
• Deegan, R, He, H B, Wood, A J, Wood, M Effect of enflurane and isoflurane on norepinephrine kinetics: a new approach to assessment of sympathetic function during anesthesia. Anesth Analg, 77(1), 49-54, 1993.
• Zhou, H H, Sheller, J R, Nu, H, Wood, M, Wood, A J Ethnic differences in response to morphine. Clin Pharmacol Ther, 54(5), 507-13, 1993.
• Stein, M, Deegan, R, Wood, A J Long-term exposure to beta 2-receptor agonist specifically desensitizes beta-receptor-mediated venodilation. Clin Pharmacol Ther, 54(2), 187-93, 1993.
• Robin, D W, Lee, M, Hasan, S S, Wood, A J Triazolam in cirrhosis: pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther, 54(6), 630-7, 1993.
• Zhou, H H, Adedoyin, A, Wood, A J Differing effect of atropine on heart rate in Chinese and white subjects. Clin Pharmacol Ther, 52(2), 120-4, 1992.
• Bluhm, R E, Bobbitt, R G, Welch, L W, Wood, A J, Bonfiglio, J F, Sarzen, C, Heath, A J, Branch, R A Elemental mercury vapour toxicity, treatment, and prognosis after acute, intensive exposure in chloralkali plant workers. Part I: History, neuropsychological findings and chelator effects. Hum Exp Toxicol, 11(3), 201-10, 1992.
• Bluhm, R E, Breyer, J A, Bobbitt, R G, Welch, L W, Wood, A J, Branch, R A Elemental mercury vapour toxicity, treatment, and prognosis after acute, intensive exposure in chloralkali plant workers. Part II: Hyperchloraemia and genitourinary symptoms. Hum Exp Toxicol, 11(3), 211-5, 1992.
• Yun, C H, Wood, M, Wood, A J, Guengerich, F P Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance. Anesthesiology, 77(3), 467-74, 1992.
• Zhou, H H, Whelan, E, Wood, A J Lack of effect of ageing on the stereochemical disposition of propranolol. Br J Clin Pharmacol, 33(1), 121-3, 1992.
• He, H B, Deegan, R J, Wood, M, Wood, A J Optimization of high-performance liquid chromatographic assay for catecholamines. Determination of optimal mobile phase composition and elimination of species-dependent differences in extraction recovery of 3,4-dihydroxybenzylamine. J Chromatogr, 574(2), 213-8, 1992.
• Edeki, T, Robin, D W, Prakash, C, Blair, I A, Wood, A J Sensitive assay for triazolam in plasma following low oral doses. J Chromatogr, 577(1), 190-4, 1992.
• Robin, D W, Hasan, S S, Lichtenstein, M J, Shiavi, R G, Wood, A J Dose-related effect of triazolam on postural sway. Clin Pharmacol Ther, 49(5), 581-8, 1991.
• Perry, S M, Whelan, E, Shay, S, Wood, A J, Wood, M Effect of i.v. anaesthesia with propofol on drug distribution and metabolism in the dog. Br J Anaesth, 66(1), 66-72, 1991.
• Deegan, R, He, H B, Wood, A J, Wood, M Effects of anesthesia on norepinephrine kinetics. Comparison of propofol and halothane anesthesia in dogs. Anesthesiology, 75(3), 481-8, 1991.
• Wood, A J, Zhou, H H Ethnic differences in drug disposition and responsiveness. Clin Pharmacokinet, 20(5), 350-73, 1991.
• Zhou, H H, Wood, A J Increased suppression of exercise-induced increase in renin by propranolol in Chinese subjects. Clin Pharmacol Ther, 50(2), 150-6, 1991.
• Funck-Brentano, C, Silberstein, D J, Roden, D M, Wood, A J, Woosley, R L A mechanism of D-(+)-sotalol effects on heart rate not related to beta-adrenoceptor antagonism. Br J Clin Pharmacol, 30(2), 195-202, 1990.
• Zhou, H H, Wood, A J Differences in stereoselective disposition of propranolol do not explain sensitivity differences between white and Chinese subjects: correlation between the clearance of (-)- and (+)-propranolol. Clin Pharmacol Ther, 47(6), 719-23, 1990.
• Zhou, H H, Anthony, L B, Wood, A J, Wilkinson, G R Induction of polymorphic 4'-hydroxylation of S-mephenytoin by rifampicin. Br J Clin Pharmacol, 30(3), 471-5, 1990.
• Naslund, T, Silberstein, D J, Merrell, W J, Nadeau, J H, Wood, A J Low sodium intake corrects abnormality in beta-receptor-mediated arterial vasodilation in patients with hypertension: correlation with beta-receptor function in vitro. Clin Pharmacol Ther, 48(1), 87-95, 1990.
• Zhou, H H, Anthony, L B, Roden, D M, Wood, A J Quinidine reduces clearance of (+)-propranolol more than (-)-propranolol through marked reduction in 4-hydroxylation. Clin Pharmacol Ther, 47(6), 686-93, 1990.
• Murray, K T, Reilly, C, Koshakji, R P, Roden, D M, Lineberry, M D, Wood, A J, Siddoway, L A, Barbey, J T, Woosley, R L Suppression of ventricular arrhythmias in man by d-propranolol independent of beta-adrenergic receptor blockade. J Clin Invest, 85(3), 836-42, 1990.
• Merrell, W J, Gordon, L, Wood, A J, Shay, S, Jackson, E K, Wood, M The effect of halothane on morphine disposition: relative contributions of the liver and kidney to morphine glucuronidation in the dog. Anesthesiology, 72(2), 308-14, 1990.
• Lee, J T, Kroemer, H K, Silberstein, D J, Funck-Brentano, C, Lineberry, M D, Wood, A J, Roden, D M, Woosley, R L The role of genetically determined polymorphic drug metabolism in the beta-blockade produced by propafenone. N Engl J Med, 322(25), 1764-8, 1990.
• Silberstein, D J, Rigby, J, Merrell, J, Naslund, T, Wood, A J Altered beta-adrenoceptor internalization does not explain reduced beta-adrenergic responsiveness in the elderly. J Clin Endocrinol Metab, 68(1), 131-4, 1989.
• Zhou, H H, Koshakji, R P, Silberstein, D J, Wilkinson, G R, Wood, A J Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites. N Engl J Med, 320(9), 565-70, 1989.
• Wood, A J Calcium antagonists. Pharmacologic differences and similarities. Circulation, 80(6 Suppl), IV184-8, 1989.
• Whelan, E, Wood, A J, Koshakji, R, Shay, S, Wood, M Halothane inhibition of propranolol metabolism is stereoselective. Anesthesiology, 71(4), 561-4, 1989.
• Shaheen, O, Biollaz, J, Koshakji, R P, Wilkinson, G R, Wood, A J Influence of debrisoquin phenotype on the inducibility of propranolol metabolism. Clin Pharmacol Ther, 45(4), 439-43, 1989.
• Zhou, H H, Silberstein, D J, Koshakji, R P, Wood, A J Interindividual differences in beta-receptor density contribute to variability in response to beta-adrenoceptor antagonists. Clin Pharmacol Ther, 45(6), 587-92, 1989.
• Whelan, E, Wood, A J, Shay, S, Wood, M Lack of effect of spinal anesthesia on drug metabolism. Anesth Analg, 69(3), 307-12, 1989.
• Anthony, L, Koshakji, R, Wood, A J Multiple pathways of propranolol's metabolism are inhibited by debrisoquin. Clin Pharmacol Ther, 46(3), 297-300, 1989.
• Prakash, C, Koshakji, R P, Wood, A J, Blair, I A Simultaneous determination of propranolol enantiomers in plasma by high-performance liquid chromatography with fluorescence detection. J Pharm Sci, 78(9), 771-5, 1989.
• Kroemer, H K, Funck-Brentano, C, Silberstein, D J, Wood, A J, Eichelbaum, M, Woosley, R L, Roden, D M Stereoselective disposition and pharmacologic activity of propafenone enantiomers. Circulation, 79(5), 1068-76, 1989.
• Bullington, J, Mouton Perry, S M, Rigby, J, Pinkerton, M, Rogers, D, Lewis, T C, Preganz, P, Wood, A J, Wood, M The effect of advancing age on the sympathetic response to laryngoscopy and tracheal intubation. Anesth Analg, 68(5), 603-8, 1989.
• Rigby, J W, Wood, A J Use of N-ethylmaleimide to directly determine the proportion of beta-adrenergic receptors exhibiting high affinity for agonists on human mononuclear leukocyte membranes. Biochem Pharmacol, 38(17), 2755-61, 1989.
• Naslund, T C, Merrell, W J, Nadeau, J H, Wood, A J Alpha-adrenergic blockade makes minimal contribution to ketanserin's hypotensive effect. Clin Pharmacol Ther, 44(6), 699-703, 1988.
• Reilly, C S, Merrell, J, Wood, A J, Koshakji, R P, Wood, M Comparison of the effects of isoflurane or fentanyl-nitrous oxide anaesthesia on propranolol disposition in dogs. Br J Anaesth, 60(7), 791-6, 1988.
• Wood, A J Drug interactions in hypertension. Hypertension, 11(3 Pt 2), II1-3, 1988.
• Koshakji, R P, Wood, A J Improved high-performance liquid chromatographic method for the simultaneous determination of propranolol and 4-hydroxypropranolol in plasma with fluorescence detection. J Chromatogr, 422294-300, 1987.