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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center

 

David B. Friedman, Ph.D.

Research Associate Professor of Biochemistry
Researcher

Contact Information:

Vanderbilt University Medical Center
9114C MRB III
Nashville, TN 37232
615-343-7333

Research Specialty

Proteomics; differential protein expression and protein/peptide mass spectrometry.

Research Description

Proteomics is the study of the dynamic protein expression of a tissue, cell type or organism. As an Associate Director of the Proteomics Laboratory in the Mass Spectrometry Research Center from 2001-2012, I directed research and technology that targets differential protein expression upon various experimental treatments/conditions (2-dimensional difference gel electrophoresis; 2D DIGE), protein identification using tandem mass spectrometry from proteins isolated from polyacrylamide gels or in complex mixtures, characterize and map sites of protein post-translational modification using tandem mass spectrometry, and quantify relative protein abundance by selected/multiple reaction monitoring tandem mass spectrometry.

Publications