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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center

 

David H. Robertson, Jr., M.D., F.A.C.P.

Elton Yates Professorship in Autonomic Disorders
Professor of Clinical Pharmacology
Professor of Neurology
Professor of Medicine
Researcher

Contact Information:

Vanderbilt University Medical Center
536 RRB
Nashville, TN 37232-6602
615-343-6499

Education
  • M.D. - Vanderbilt University, 1973
  • Fellowship - Vanderbilt University Medical Center, 1977
  • Residency - Johns Hopkins Hospital and Health System, 1975
  • Internship - Johns Hopkins Hospital and Health System, 1974
 
Research Description

Our laboratory is interested in identifying the mechanisms of neural regulation of heart rate and blood pressure in normal individuals, as well as in patients with cardiovascular, psychiatric or neurological disorders. Using a bench-to-bedside approach that merges our clinical research and our basic research, we have successfully identified the previously unrecognized disorders of dopamine -hydroxylase deficiency, baroreflex failure, and norepinephrine transporter deficiency. New therapeutic advances have been a natural follow-up to these discoveries.

Investigative strengths of our laboratory include genetic linkage studies and identification of polymorphisms in candidate genes relevant to autonomic neuroscience. The laboratory focuses on transgenic mice as models of human disease, examining whole animal physiology and using radio telemetry, power spectral analysis, bioengineering, and pharmacologic testing in phenotyping relevant knock-out mice.

Publications
  • Hollenbeck R, Black BK, Peltier AC, Biaggioni I, Robertson D, Winton EF, Raj SR. Long-term treatment with rituximab of autoimmune autonomic ganglionopathy in a patient with lymphoma. Arch. Neurol [print-electronic]. 2011 Mar; 68(3): 372-5. PMID: 21059985, PMCID: PMC3725638, PII: archneurol.2010.289, DOI: 10.1001/archneurol.2010.289, ISSN: 1538-3687.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21059985.
  • Shibao C, Okamoto LE, Gamboa A, Yu C, Diedrich A, Raj SR, Robertson D, Biaggioni I. Comparative efficacy of yohimbine against pyridostigmine for the treatment of orthostatic hypotension in autonomic failure. Hypertension [print-electronic]. 2010 Nov; 56(5): 847-51. PMID: 20837887, PMCID: PMC2959129, PII: HYPERTENSIONAHA.110.154898, DOI: 10.1161/HYPERTENSIONAHA.110.154898, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20837887.
  • English BA, Appalsamy M, Diedrich A, Ruggiero AM, Lund D, Wright J, Keller NR, Louderback KM, Robertson D, Blakely RD. Tachycardia, reduced vagal capacity, and age-dependent ventricular dysfunction arising from diminished expression of the presynaptic choline transporter. Am. J. Physiol. Heart Circ. Physiol [print-electronic]. 2010 Sep; 299(3): H799-810. PMID: 20601463, PMCID: PMC2944482, PII: ajpheart.00170.2010, DOI: 10.1152/ajpheart.00170.2010, ISSN: 1522-1539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20601463.
  • Sato K, Urbano R, Yu C, Yamasaki F, Sato T, Jordan J, Robertson D, Diedrich A. The effect of donepezil treatment on cardiovascular mortality. Clin. Pharmacol. Ther [print-electronic]. 2010 Sep; 88(3): 335-8. PMID: 20664535, PMCID: PMC3120840, PII: clpt201098, DOI: 10.1038/clpt.2010.98, ISSN: 1532-6535.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20664535.
  • McHugh J, Keller NR, Appalsamy M, Thomas SA, Raj SR, Diedrich A, Biaggioni I, Jordan J, Robertson D. Portal osmopressor mechanism linked to transient receptor potential vanilloid 4 and blood pressure control. Hypertension [print-electronic]. 2010 Jun; 55(6): 1438-43. PMID: 20385965, PMCID: PMC2965336, PII: HYPERTENSIONAHA.110.151860, DOI: 10.1161/HYPERTENSIONAHA.110.151860, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20385965.
  • Pulley J, Hassan NN, Bernard GR, Jirjis JN, Schildcrout J, Robertson D, Masys DR, Harris P. Identifying unpredicted drug benefit through query of patient experiential knowledge: a proof of concept web-based system. Clin Transl Sci. 2010 Jun; 3(3): 98-103. PMID: 20590678, PMCID: PMC2910903, PII: CTS200, DOI: 10.1111/j.1752-8062.2010.00200.x, ISSN: 1752-8062.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20590678.
  • Peltier AC, Garland E, Raj SR, Sato K, Black B, Song Y, Wang L, Biaggioni I, Diedrich A, Robertson D. Distal sudomotor findings in postural tachycardia syndrome. Clin. Auton. Res [print-electronic]. 2010 Apr; 20(2): 93-9. PMID: 20035362, PMCID: PMC3089763, DOI: 10.1007/s10286-009-0045-y, ISSN: 1619-1560.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20035362.
  • Peltier AC, Black BK, Raj SR, Donofrio P, Robertson D, Biaggioni I. Coexistent autoimmune autonomic ganglionopathy and myasthenia gravis associated with non-small-cell lung cancer. Muscle Nerve. 2010 Mar; 41(3): 416-9. PMID: 19882640, PMCID: PMC3925506, DOI: 10.1002/mus.21528, ISSN: 1097-4598.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19882640.
  • Garland EM, Gamboa A, Okamoto L, Raj SR, Black BK, Davis TL, Biaggioni I, Robertson D. Renal impairment of pure autonomic failure. Hypertension [print-electronic]. 2009 Nov; 54(5): 1057-61. PMID: 19738158, PMCID: PMC2796115, PII: HYPERTENSIONAHA.109.136853, DOI: 10.1161/HYPERTENSIONAHA.109.136853, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19738158.
  • Raj SR, Black BK, Biaggioni I, Paranjape SY, Ramirez M, Dupont WD, Robertson D. Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more. Circulation [print-electronic]. 2009 Sep 9/1/2009; 120(9): 725-34. PMID: 19687359, PMCID: PMC2758650, PII: CIRCULATIONAHA.108.846501, DOI: 10.1161/CIRCULATIONAHA.108.846501, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19687359.
  • Diedrich A, Porta A, Barbic F, Brychta RJ, Bonizzi P, Diedrich L, Cerutti S, Robertson D, Furlan R. Lateralization of expression of neural sympathetic activity to the vessels and effects of carotid baroreceptor stimulation. Am. J. Physiol. Heart Circ. Physiol [print-electronic]. 2009 Jun; 296(6): H1758-65. PMID: 19363133, PMCID: PMC2716107, PII: 01045.2008, DOI: 10.1152/ajpheart.01045.2008, ISSN: 0363-6135.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19363133.
  • Raj V, Haman KL, Raj SR, Byrne D, Blakely RD, Biaggioni I, Robertson D, Shelton RC. Psychiatric profile and attention deficits in postural tachycardia syndrome. J. Neurol. Neurosurg. Psychiatr [print-electronic]. 2009 Mar; 80(3): 339-44. PMID: 18977825, PMCID: PMC2758320, PII: jnnp.2008.144360, DOI: 10.1136/jnnp.2008.144360, ISSN: 1468-330X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18977825.
  • Okamoto LE, Gamboa A, Shibao C, Black BK, Diedrich A, Raj SR, Robertson D, Biaggioni I. Nocturnal blood pressure dipping in the hypertension of autonomic failure. Hypertension [print-electronic]. 2009 Feb; 53(2): 363-9. PMID: 19047577, PMCID: PMC2665259, PII: HYPERTENSIONAHA.108.124552, DOI: 10.1161/HYPERTENSIONAHA.108.124552, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19047577.
  • Chung OY, Bruehl S, Diedrich L, Diedrich A, Chont M, Robertson D. Baroreflex sensitivity associated hypoalgesia in healthy states is altered by chronic pain. Pain [print-electronic]. 2008 Aug 8/15/2008; 138(1): 87-97. PMID: 18164819, PII: S0304-3959(07)00688-4, DOI: 10.1016/j.pain.2007.11.011, ISSN: 1872-6623.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18164819.
  • Gamboa A, Shibao C, Diedrich A, Paranjape SY, Farley G, Christman B, Raj SR, Robertson D, Biaggioni I. Excessive nitric oxide function and blood pressure regulation in patients with autonomic failure. Hypertension [print-electronic]. 2008 Jun; 51(6): 1531-6. PMID: 18426998, PMCID: PMC2497433, PII: HYPERTENSIONAHA.107.105171, DOI: 10.1161/HYPERTENSIONAHA.107.105171, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18426998.
  • Robertson D. The pathophysiology and diagnosis of orthostatic hypotension. Clin. Auton. Res [print-electronic]. 2008 Mar; 18 Suppl 1: 2-7. PMID: 18368300, DOI: 10.1007/s10286-007-1004-0, ISSN: 0959-9851.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18368300.
  • Bruehl S, Chung OY, Diedrich L, Diedrich A, Robertson D. The relationship between resting blood pressure and acute pain sensitivity: effects of chronic pain and alpha-2 adrenergic blockade. J Behav Med [print-electronic]. 2008 Feb; 31(1): 71-80. PMID: 17940860, DOI: 10.1007/s10865-007-9133-4, ISSN: 1573-3521.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17940860.
  • Garland EM, Raj SR, Black BK, Harris PA, Robertson D. The hemodynamic and neurohumoral phenotype of postural tachycardia syndrome. Neurology. 2007 Aug 8/21/2007; 69(8): 790-8. PMID: 17709712, PII: 69/8/790, DOI: 10.1212/01.wnl.0000267663.05398.40, ISSN: 1526-632X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17709712.
  • Diedrich A, Paranjape SY, Robertson D. Plasma and blood volume in space. Am. J. Med. Sci. 2007 Jul; 334(1): 80-5. PMID: 17630598, PII: 00000441-200707000-00024, DOI: 10.1097/MAJ.0b013e318065b89b, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17630598.
  • Garland EM, Black BK, Harris PA, Robertson D. Dopamine-beta-hydroxylase in postural tachycardia syndrome. Am. J. Physiol. Heart Circ. Physiol. 2007 Jul; 293(1): H684-90. PMID: 17625104, PII: 293/1/H684, DOI: 10.1152/ajpheart.01389.2006, ISSN: 0363-6135.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17625104.
  • Raj SR, Robertson D. Blood volume perturbations in the postural tachycardia syndrome. Am. J. Med. Sci. 2007 Jul; 334(1): 57-60. PMID: 17630594, PII: 00000441-200707000-00020, DOI: 10.1097/MAJ.0b013e318063c6c0, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17630594.
  • Shibao C, Raj SR, Gamboa A, Diedrich A, Choi L, Black BK, Robertson D, Biaggioni I. Norepinephrine transporter blockade with atomoxetine induces hypertension in patients with impaired autonomic function. Hypertension [print-electronic]. 2007 Jul; 50(1): 47-53. PMID: 17515448, PII: HYPERTENSIONAHA.107.089961, DOI: 10.1161/HYPERTENSIONAHA.107.089961, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17515448.
  • Diedrich A, Malow BA, Antic NA, Sato K, McEvoy RD, Mathias CJ, Robertson D, Berry-Kravis EM, Weese-Mayer DE. Vagal and sympathetic heart rate and blood pressure control in adult onset PHOX2B mutation-confirmed congenital central hypoventilation syndrome. Clin. Auton. Res [print-electronic]. 2007 Jun; 17(3): 177-85. PMID: 17541758, DOI: 10.1007/s10286-007-0421-4, ISSN: 0959-9851.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17541758.
  • Dzurik MV, Diedrich A, Black B, Paranjape SY, Raj SR, Byrne DW, Robertson D. Endogenous substance P modulates human cardiovascular regulation at rest and during orthostatic load. J. Appl. Physiol [print-electronic]. 2007 Jun; 102(6): 2092-7. PMID: 17255371, PII: 00969.2006, DOI: 10.1152/japplphysiol.00969.2006, ISSN: 8750-7587.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17255371.
  • Brychta RJ, Shiavi R, Robertson D, Diedrich A. Spike detection in human muscle sympathetic nerve activity using the kurtosis of stationary wavelet transform coefficients. J. Neurosci. Methods [print-electronic]. 2007 Mar 3/15/2007; 160(2): 359-67. PMID: 17083982, PMCID: PMC2075105, PII: S0165-0270(06)00473-0, DOI: 10.1016/j.jneumeth.2006.09.020, ISSN: 0165-0270.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17083982.
  • Brychta RJ, Shiavi R, Robertson D, Biaggioni I, Diedrich A. A simplified two-component model of blood pressure fluctuation. Am. J. Physiol. Heart Circ. Physiol [print-electronic]. 2007 Feb; 292(2): H1193-203. PMID: 17012354, PMCID: PMC1987355, PII: 00645.2006, DOI: 10.1152/ajpheart.00645.2006, ISSN: 0363-6135.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17012354.
  • Taneja I, Haman K, Shelton RC, Robertson D. A randomized, double-blind, crossover trial of modafinil on mood. J Clin Psychopharmacol. 2007 Feb; 27(1): 76-9. PMID: 17224718, PII: 00004714-200702000-00015, DOI: 10.1097/jcp.0b013e31802eb7ea, ISSN: 0271-0749.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17224718.
  • Brychta RJ, Tuntrakool S, Appalsamy M, Keller NR, Robertson D, Shiavi RG, Diedrich A. Wavelet methods for spike detection in mouse renal sympathetic nerve activity. IEEE Trans Biomed Eng. 2007 Jan; 54(1): 82-93. PMID: 17260859, PMCID: PMC2075098, DOI: 10.1109/TBME.2006.883830, ISSN: 0018-9294.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17260859.
  • Fessel J, Robertson D. Orthostatic hypertension: when pressor reflexes overcompensate. Nat Clin Pract Nephrol. 2006 Aug; 2(8): 424-31. PMID: 16932477, PII: ncpneph0228, DOI: 10.1038/ncpneph0228, ISSN: 1745-8323.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16932477.
  • Raj SR, Biaggioni I, Black BK, Rali A, Jordan J, Taneja I, Harris PA, Robertson D. Sodium paradoxically reduces the gastropressor response in patients with orthostatic hypotension. Hypertension [print-electronic]. 2006 Aug; 48(2): 329-34. PMID: 16785332, PII: 01.HYP.0000229906.27330.4f, DOI: 10.1161/01.HYP.0000229906.27330.4f, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16785332.
  • Shibao C, Gamboa A, Abraham R, Raj SR, Diedrich A, Black B, Robertson D, Biaggioni I. Clonidine for the treatment of supine hypertension and pressure natriuresis in autonomic failure. Hypertension [print-electronic]. 2006 Mar; 47(3): 522-6. PMID: 16391172, PII: 01.HYP.0000199982.71858.11, DOI: 10.1161/01.HYP.0000199982.71858.11, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16391172.
  • Goldner F, Jacob G, Raj SR, Robertson D. The importance of recognizing postural pseudoanemia. Compr Ther. 2006; 32(1): 51-5. PMID: 16785584, PII: COMP:32:1:51, ISSN: 0098-8243.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16785584.
  • Jacob G, Garland EM, Costa F, Stein CM, Xie HG, Robertson RM, Biaggioni I, Robertson D.. β2-ad renoceptor genotype and function affect hemodynamic profile heterogeneity in postural tachycardia syndrome. Hypertension. 2006; 47((3)): 421-7.
  • Keller NR, Diedrich A, Appalsamy M, Miller LC, Caron MG, McDonald MP, Shelton RC, Blakely RD, Robertson D. Norepinephrine transporter-deficient mice respond to anxiety producing and fearful environments with bradycardia and hypotension. Neuroscience [print-electronic]. 2006; 139(3): 931-46. PMID: 16515844, PII: S0306-4522(06)00099-6, DOI: 10.1016/j.neuroscience.2006.01.008, ISSN: 0306-4522.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16515844.
  • Garland EM, Raj SR, Demartinis N, Robertson D. Case report: Marathon runner with severe autonomic failure. Lancet. 2005 Dec; 366 Suppl 1: S13. PMID: 16360730, PII: S0140-6736(05)67826-9, DOI: 10.1016/S0140-6736(05)67826-9, ISSN: 1474-547X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16360730.
  • Garland EM, Winker R, Williams SM, Jiang L, Stanton K, Byrne DW, Biaggioni I, Cascorbi I, Phillips JA, Harris PA, Rüdiger H, Robertson D. Endothelial NO synthase polymorphisms and postural tachycardia syndrome. Hypertension [print-electronic]. 2005 Nov; 46(5): 1103-10. PMID: 16203873, PII: 01.HYP.0000185462.08685.da, DOI: 10.1161/01.HYP.0000185462.08685.da, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16203873.
  • Raj SR, Black BK, Biaggioni I, Harris PA, Robertson D. Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome. Circulation [print-electronic]. 2005 May 5/31/2005; 111(21): 2734-40. PMID: 15911704, PII: CIRCULATIONAHA.104.497594, DOI: 10.1161/CIRCULATIONAHA.104.497594, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15911704.
  • Jacob G, Raj SR, Ketch T, Pavlin B, Biaggioni I, Ertl AC, Robertson D. Postural pseudoanemia: posture-dependent change in hematocrit. Mayo Clin. Proc. 2005 May; 80(5): 611-4. PMID: 15887428, PII: S0025-6196(11)63092-9, DOI: 10.4065/80.5.611, ISSN: 0025-6196.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15887428.
  • Raj SR, Biaggioni I, Yamhure PC, Black BK, Paranjape SY, Byrne DW, Robertson D. Renin-aldosterone paradox and perturbed blood volume regulation underlying postural tachycardia syndrome. Circulation [print-electronic]. 2005 Apr 4/5/2005; 111(13): 1574-82. PMID: 15781744, PII: 01.CIR.0000160356.97313.5D, DOI: 10.1161/01.CIR.0000160356.97313.5D, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15781744.
  • Taneja I, Diedrich A, Black BK, Byrne DW, Paranjape SY, Robertson D. Modafinil elicits sympathomedullary activation. Hypertension [print-electronic]. 2005 Apr; 45(4): 612-8. PMID: 15753235, PII: 01.HYP.0000158267.66763.63, DOI: 10.1161/01.HYP.0000158267.66763.63, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15753235.
  • Christou D, Jones P, Jordan J, Diedrich A, Robertson D, Seals D.. Women have lower tonic autonomic support of arterial blood pressure and less effective baroreflex buffering than men. Circulation. 2005; 111: 494-8.
  • Jacob G, Gamboa A, Diedrich A, Shibao C, Robertson D, Biaggioni I.. Tyramine-induced vasodilation mediated by dopamine contamination: a paradox resolved. Hypertension. 2005; 46: 355-9.
  • Winker R; Barth A; Bidmon D; Ponocny I; Weber M; Mayr O; Robertson D; Diedrich A; Maier R; Pilger A; Haber P; Rudiger HW.. Endurance exercise training in orthostatic intolerance - A randomized, controlled trial. Hypertension. 2005; 45: 391-8.
  • Garland EM, Vnencak-Jones CL, Biaggioni I, Davis TL, Montine TJ, Robertson D. Fragile X gene premutation in multiple system atrophy. J. Neurol. Sci. 2004 Dec 12/15/2004; 227(1): 115-8. PMID: 15546601, PII: S0022-510X(04)00320-X, DOI: 10.1016/j.jns.2004.08.013, ISSN: 0022-510X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15546601.
  • Taneja I, Bruehl S, Robertson D. Effect of modafinil on acute pain: a randomized double-blind crossover study. J Clin Pharmacol. 2004 Dec; 44(12): 1425-7. PMID: 15545315, PII: 44/12/1425, DOI: 10.1177/0091270004270292, ISSN: 0091-2700.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15545315.
  • Oeltmann T, Carson R, Shannon JR, Ketch T, Robertson D. Assessment of O-methylated catecholamine levels in plasma and urine for diagnosis of autonomic disorders. Auton Neurosci. 2004 Nov 11/30/2004; 116(1-2): 1-10. PMID: 15556832, PII: S1566-0702(04)00200-0, DOI: 10.1016/j.autneu.2004.08.013, ISSN: 1566-0702.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15556832.
  • Vincent S, Bieck PR, Garland EM, Loghin C, Bymaster FP, Black BK, Gonzales C, Potter WZ, Robertson D. Clinical assessment of norepinephrine transporter blockade through biochemical and pharmacological profiles. Circulation [print-electronic]. 2004 Jun 6/29/2004; 109(25): 3202-7. PMID: 15184278, PII: 01.CIR.0000130847.18666.39, DOI: 10.1161/01.CIR.0000130847.18666.39, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15184278.
  • Taneja I, Marney A, Robertson D. Aortic stenosis and autonomic dysfunction: co-conspirators in syncope. Am. J. Med. Sci. 2004 May; 327(5): 281-3. PMID: 15166752, PII: 00000441-200405000-00030, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15166752.
  • Jordan J, Shannon JR, Diedrich A, Black B, Robertson D, Biaggioni I. Water potentiates the pressor effect of ephedra alkaloids. Circulation [print-electronic]. 2004 Apr 4/20/2004; 109(15): 1823-5. PMID: 15066944, PII: 01.CIR.0000126283.99195.37, DOI: 10.1161/01.CIR.0000126283.99195.37, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15066944.
  • Usera PC, Vincent S, Robertson D. Human phenotypes and animal knockout models of genetic autonomic disorders. J. Biomed. Sci. 2004 Jan; 11(1): 4-10. PMID: 14730204, PII: 75283, DOI: 10.1159/000075283, ISSN: 1021-7770.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14730204.
  • Lucini D, Furlan R, Villa P, Robertson D, et al.. Altered profile of baroreflex and autonomic responses to lower body negative pressure in chronic orthostatic intolerance. Journal of Hypertension. 2004; 22: 1535-42.
  • Meck JV, Robertson D, Waters WW, Ziegler MG, et al.. Mechanisms of postspaceflight orthostatic hypotension: low alpha(1)-adrenergic receptor responses before flight and central autonomic dysregulation postflight. Am J Physiol-Heart C. 2004; 286.
  • Taneja I, Robertson D. Genetic basis of autonomic dysfunction. Semin Neurol. 2003 Dec; 23(4): 391-7. PMID: 15088260, DOI: 10.1055/s-2004-817723, ISSN: 0271-8235.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15088260.
  • Lu CC, Diedrich A, Tung CS, Paranjape SY, Harris PA, Byrne DW, Jordan J, Robertson D. Water ingestion as prophylaxis against syncope. Circulation [print-electronic]. 2003 Nov 11/25/2003; 108(21): 2660-5. PMID: 14623807, PII: 01.CIR.0000101966.24899.CB, DOI: 10.1161/01.CIR.0000101966.24899.CB, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14623807.
  • Singleton CD, Robertson D, Byrne DW, Joos KM. Effect of posture on blood and intraocular pressures in multiple system atrophy, pure autonomic failure, and baroreflex failure. Circulation [print-electronic]. 2003 Nov 11/11/2003; 108(19): 2349-54. PMID: 14597588, PII: 01.CIR.0000097114.11038.26, DOI: 10.1161/01.CIR.0000097114.11038.26, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14597588.
  • Diedrich A, Jordan J, Tank J, Shannon JR, Robertson R, Luft FC, Robertson D, Biaggioni I. The sympathetic nervous system in hypertension: assessment by blood pressure variability and ganglionic blockade. J. Hypertens. 2003 Sep; 21(9): 1677-86. PMID: 12923400, DOI: 10.1097/01.hjh.0000084711.87421.07, ISSN: 0263-6352.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12923400.
  • Hahn MK, Robertson D, Blakely RD. A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters. J. Neurosci. 2003 Jun 6/1/2003; 23(11): 4470-8. PMID: 12805287, PII: 23/11/4470, ISSN: 1529-2401.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12805287.
  • Cho S, Kim CH, Cubells JF, Zabetian CP, Hwang DY, Kim JW, Cohen BM, Biaggioni I, Robertson D, Kim KS.. Variations in the dopamine beta-hydroxylase gene are not associated with the autonomic disorders, pure autonomic failure, or multiple system atrophy. Am J Med Genet. 2003; 120A: 234-6.
  • Cuajungco MP, Ando Y, Axelrod FB et al.. Hereditary dysautonomias: current knowledge and collaboration for the future. Clin Auto Res. 2003; 13: 180-95.
  • Furlan R, Diedrich A, Rimold A et al.. Effects of unliateral and bilateral carotid baroreflex stimulation on cardiac and neural sympathetic discharge oscillatory patterns. Circulation. 2003; 108: 717-23.
  • Gliasson BI, Mabon ME, Duda JE, Montine TJ, Robertson D, Hurtig HI, Lee VMY, Trojanowski.. Tau and 14-3-3 in glial cytoplasmic inclusions of multiple system atrophy. Acta Neurol. 2003; 106: 243-50.
  • Jacob G, Costa F, Vincent S, Robertson D, Biaggioni I.. Neurovascular dissociation with paradoxical forearm vasodilation during systemic tyramine administration. Circulation. 2003; 107: 2475-9.
  • Murff HF, Byrne DW, Harris PA et al.. A model for the development of a “near-miss” reporting system for a General Clinical Research Center. J Invest Med. 2003; 51: S379.
  • Singleton CD, Robertson D, Byrne DW, et al. Effect of posture on blood and intraocular pressures in multiple system atrophy, pure autonomic failure, and baroreflex failure. Circulation. 2003; 108: 2349-54.
  • Zabetian CP, Romero R, Robertson D et al. A revised allele frequency estimate and haplotype analysis of the DBH deficiency mutation IVS1+2T->C in African- and European-Americans. Am J Med Genet. 2003; 132A: 190-2.
  • Carson RP, Diedrich A, Robertson D. Autonomic control after blockade of the norepinephrine transporter: a model of orthostatic intolerance. J. Appl. Physiol [print-electronic]. 2002 Dec; 93(6): 2192-8. PMID: 12391111, PII: 00033.2002, DOI: 10.1152/japplphysiol.00033.2002, ISSN: 8750-7587.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12391111.
  • Garland EM, Anderson JC, Black BK, Kessler RM, Konrad PE, Robertson D. No increased herniation of the cerebellar tonsils in a group of patients with orthostatic intolerance. Clin. Auton. Res. 2002 Dec; 12(6): 472-6. PMID: 12598952, DOI: 10.1007/s10286-002-0051-9, ISSN: 0959-9851.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12598952.
  • Diedrich A, Jordan J, Shannon JR, Robertson D, Biaggioni I. Modulation of QT interval during autonomic nervous system blockade in humans. Circulation. 2002 Oct 10/22/2002; 106(17): 2238-43. PMID: 12390954, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12390954.
  • Garland EM, Hahn MK, Ketch TP, Keller NR, Kim CH, Kim KS, Biaggioni I, Shannon JR, Blakely RD, Robertson D. Genetic basis of clinical catecholamine disorders. Ann. N. Y. Acad. Sci. 2002 Oct; 971: 506-14. PMID: 12438171, ISSN: 0077-8923.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12438171.
  • Parikh SM, Diedrich A, Biaggioni I, Robertson D. The nature of the autonomic dysfunction in multiple system atrophy. J. Neurol. Sci. 2002 Aug 8/15/2002; 200(1-2): 1-10. PMID: 12127669, PII: S0022510X02001260, ISSN: 0022-510X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12127669.
  • Ketch T, Biaggioni I, Robertson R, Robertson D. Four faces of baroreflex failure: hypertensive crisis, volatile hypertension, orthostatic tachycardia, and malignant vagotonia. Circulation. 2002 May 5/28/2002; 105(21): 2518-23. PMID: 12034659, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12034659.
  • Carson RP, Robertson D. Genetic manipulation of noradrenergic neurons. J. Pharmacol. Exp. Ther. 2002 May; 301(2): 410-7. PMID: 11961038, ISSN: 0022-3565.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11961038.
  • Vincent S, Robertson D. The broader view: catecholamine abnormalities. Clin. Auton. Res. 2002 May; 12 Suppl 1: I44-9. PMID: 12102462, ISSN: 0959-9851.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12102462.
  • Shannon JR, Diedrich A, Biaggioni I, Tank J, Robertson RM, Robertson D, Jordan J. Water drinking as a treatment for orthostatic syndromes. Am. J. Med. 2002 Apr 4/1/2002; 112(5): 355-60. PMID: 11904109, PII: S0002934302010252, ISSN: 0002-9343.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11904109.
  • Ertl AC, Diedrich A, Biaggioni I, Levine BD, Robertson RM, Cox JF, Zuckerman JH, Pawelczyk JA, Ray CA, Buckey JC, Lane LD, Shiavi R, Gaffney FA, Costa F, Holt C, Blomqvist CG, Eckberg DL, Baisch FJ, Robertson D. Human muscle sympathetic nerve activity and plasma noradrenaline kinetics in space. J. Physiol. (Lond.). 2002 Jan 1/1/2002; 538(Pt 1): 321-9. PMID: 11773339, PMCID: PMC2290013, PII: PHY_12576, ISSN: 0022-3751.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11773339.
  • Zhang J, Montine TJ, Smith MA, Siedlak SL, Gu G, Robertson D, Perry G. The mitochondrial common deletion in Parkinson's disease and related movement disorders. Parkinsonism Relat. Disord. 2002 Jan; 8(3): 165-70. PMID: 12039426, PII: S1353802001000414, ISSN: 1353-8020.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12039426.
  • Carson RP, Diedrich A, Robertson D.. Autonomic control after blockade of the norepinephrine transporter: a model of orthostatic intolerance. J Appl Physiol. 2002; 93: 2192-8.
  • Ertl AC, Diedrich AC, Biaggioni I, Robertson RM, Levine B, Cox J, Pawelczyk JP, Ray CA, Blomqvist G, Eckberg D, Baisch F, Robertson D. Sympathetic nerve activity and plasma noradrenaline kinetics in space. J Physiol. 2002; 538.1: 321-9.
  • Robertson D, Jordan J, Jacob G, Ketch T, Shannon JR, Biaggioni I. Ageing and water homeostasis. Novartis Found. Symp. 2002; 242: 265-75; discussion 275. PMID: 11855693, ISSN: 1528-2511.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11855693.
  • Robertson D, Tung CS. Linking molecular and bedside research: designing a clinical research infrastructure. J. Mol. Med [print-electronic]. 2001 Dec; 79(12): 686-94. PMID: 11862312, DOI: 10.1007/s00109-001-0298-y, ISSN: 0946-2716.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11862312.
  • Tellioglu T, Robertson D. Genetic or acquired deficits in the norepinephrine transporter: current understanding of clinical implications. Expert reviews in molecular medicine. 2001 Nov 11/19/2001; 2001 Sect. 1,10.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14987367.
  • Garland EM, Robertson D. Chiari I malformation as a cause of orthostatic intolerance symptoms: a media myth?. Am. J. Med. 2001 Nov; 111(7): 546-52. PMID: 11705431, PII: S0002-9343(01)00922-6, ISSN: 0002-9343.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11705431.
  • Robertson D, Shannon JR, Jordan J, Davis TL, Diedrich A, Jacob G, Garland E, Tellioglu T, Biaggioni I. Multiple system atrophy: new developments in pathophysiology and therapy. Parkinsonism Relat. Disord. 2001 Jul; 7(3): 257-60. PMID: 11331196, PII: S1353-8020(00)00067-5, ISSN: 1873-5126.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11331196.
  • Tellioglu T, Robertson D. Orthostatic intolerance in Behcet's disease. Auton Neurosci. 2001 Jun 6/20/2001; 89(1-2): 96-9. PMID: 11474652, PII: S1566-0702(01)00243-0, DOI: 10.1016/S1566-0702(01)00243-0, ISSN: 1566-0702.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11474652.
  • Carson RP, Appalsamy M, Diedrich A, Davis TL, Robertson D. Animal model of neuropathic tachycardia syndrome. Hypertension. 2001 Jun; 37(6): 1357-61. PMID: 11408377, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11408377.
  • Robertson D, Flattem N, Tellioglu T, Carson R, Garland E, Shannon JR, Jordan J, Jacob G, Blakely RD, Biaggioni I. Familial orthostatic tachycardia due to norepinephrine transporter deficiency. Ann. N. Y. Acad. Sci. 2001 Jun; 940: 527-43. PMID: 11458707, ISSN: 0077-8923.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11458707.
  • Robertson D. Electronic publishing of science: better late than never. Am. J. Med. 2001 Apr 4/1/2001; 110(5): 370-2. PMID: 11286951, PII: S0002-9343(01)00657-X, ISSN: 0002-9343.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11286951.
  • Carson RP, Appalsamy M, Diedrich A, Davis TL, Robertson D. Animal model of neuropathic tachycardia syndrome. Hypertension. 2001; 37: 1357-61.
  • Robertson D, Shannon JR, Jordan J, Davis TL, Diedrich A, Jacob G, Garland E, Tellioglu T, Biaggioni I. Multiple system atrophy: new developments in pathophysiology and therapy. Parkinsonism Relat. Disord. 2001; 7: 257-60.
  • Robertson D. Biomedical research electronic publishing: Better late than never. Am J Med. 2001; 110: 370-2.
  • Robertson D. Clinical approach to the functional dysautonomias. J Functional Syndromes. 2001; 1: 54-60.
  • Ertl AC, Diedrich A, Biaggioni I. Baroreflex dysfunction induced by microgravity: potential relevance to postflight orthostatic intolerance. Clin. Auton. Res. 2000 Oct; 10(5): 269-77. PMID: 11198482, ISSN: 0959-9851.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11198482.
  • Robertson D. The future of clinical research. J. Investig. Med. 2000 Sep; 48(5): 309-11. PMID: 10979235, ISSN: 1081-5589.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10979235.
  • Shannon JR, Jordan J, Diedrich A, Pohar B, Black BK, Robertson D, Biaggioni I. Sympathetically mediated hypertension in autonomic failure. Circulation. 2000 Jun 6/13/2000; 101(23): 2710-5. PMID: 10851208, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10851208.
  • Ali YS, Daamen N, Jacob G, Jordan J, Shannon JR, Biaggioni I, Robertson D. Orthostatic intolerance: a disorder of young women. Obstet Gynecol Surv. 2000 Apr; 55(4): 251-9. PMID: 10758621, ISSN: 0029-7828.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10758621.
  • Shannon JR, Flattem NL, Jordan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D. Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency. N. Engl. J. Med. 2000 Feb 2/24/2000; 342(8): 541-9. PMID: 10684912, DOI: 10.1056/NEJM200002243420803, ISSN: 0028-4793.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10684912.
  • Jacob G, Costa F, Shannon J, Robertson D, Biaggioni I. Dissociation between neural and vascular responses to sympathetic stimulation : contribution of local adrenergic receptor function. Hypertension. 2000 Jan; 35(1 Pt 1): 76-81. PMID: 10642278, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10642278.
  • Duda JE, Giasson BI, Gur TL, Montine TJ, Robertson D, Biaggioni I, Hurtig HI, Stern MB, Gollump SM, Grossman M, Lee VM-Y, Trojanowski JQ. Immunohistochemical and biochemical studies demonstrate a distinct profile of "-synuclein permutations in multiple system atrophy. J Neuropath Exper Neurol. 2000; 59: 830-41.
  • Furlan R, Porta A, Costa F, Tank J, Baker L, Schiavi R, Robertson D, Malliani A, Mosqueda-Garcia R. Oscillatory patterns in sympathetic neural discharge and cardiovascular variables during orthostatic stimulation. Circulation. 2000; 101: 886-92.
  • Jacob G, Shannon JR, Costa F, Robertson RM, Wathen M, Stein M, Biaggioni I, Ertl AC, Black B, Robertson D. Neuropathic postural tachycardia syndrome. N Engl J Med. 2000; 343: 1008-14.
  • Jordan J, Shannon JR, Diedrich A, Black B, Costa F, Robertson D, Biaggioni I. Interaction of carbon dioxide and sympathetic nervous system activity in the regulation of cerebral perfusion in humans. Hypertension. 2000; 36: 383-8.
  • Robertson D, Shannon JR, Biaggioni I, Ertl AC, Diedrich A, Carson R, Furlan R, Jacob G, Jordan J, . Orthostatic intolerance and the postural tachycardia syndrome: genetic and environment pathophysiologies. Neurolab Autonomic Team. Pflugers Arch. 2000; 441(2-3 Suppl): R48-51. PMID: 11200979, ISSN: 0031-6768.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11200979.
  • Robertson D, Shannon JR, Biaggioni I, Ertl AC, Diedrich AD, Carson R, Furlan R, Jacob G, Jordan J, and the Neurolab Autonomic Team. Orthostatic intolerance and the postural tachycardia syndrome: Genetic and environment pathophysiologies. Eur J Physiol. 2000; 441: R48-R51.
  • Robertson D. Reinventing the General Clinical Research Centers for the post-genome era. Meyer R (ed) Ensuring the Future of Clinical Research. (Washington: Association of American Medical Colleges). 2000; 37-46.
  • Robertson D. The future of clinical research. J Invest Med. 2000; 48: 309-11.
  • Shannon JR, Flattem NL, Jordan J, Jacob G, Black BK, Biaggioni I, Blakely RD, Robertson D. Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency. New Engl. J. Med. 2000; 342: 541-9.
  • Shannon JR, Jordan J, Diedrich A, Pohar B, Black BK, Robertson D, Biaggioni I. Sympathetically mediated hypertension in autonomic failure. Circulation. 2000; 101: 2710-5.
  • Robertson D, Biaggioni I, Ertl AC, Robertson RM, Diedrich A, Blakely RD, Flattem N, Shannon JR. Orthostatic intolerance: emerging genetic and environmental etiologies. J Gravit Physiol. 1999 Jul; 6(1): P51-4. PMID: 11543025, ISSN: 1077-9248.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11543025.
  • Shannon JR, Gottesdiener K, Jordan J, Chen K, Flattery S, Larson PJ, Candelore MR, Gertz B, Robertson D, Sun M. Acute effect of ephedrine on 24-h energy balance. Clin. Sci. 1999 May; 96(5): 483-91. PMID: 10209080, ISSN: 0143-5221.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10209080.
  • Zhang J, Perry G, Smith MA, Robertson D, Olson SJ, Graham DG, Montine TJ. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am. J. Pathol. 1999 May; 154(5): 1423-9. PMID: 10329595, PMCID: PMC1866598, PII: S0002-9440(10)65396-5, DOI: 10.1016/S0002-9440(10)65396-5, ISSN: 0002-9440.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10329595.
  • Jacob G, Shannon JR, Costa F, Furlan R, Biaggioni I, Mosqueda-Garcia R, Robertson RM, Robertson D. Abnormal norepinephrine clearance and adrenergic receptor sensitivity in idiopathic orthostatic intolerance. Circulation. 1999 Apr 4/6/1999; 99(13): 1706-12. PMID: 10190880, ISSN: 0009-7322.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10190880.
  • Montine TJ, Beal MF, Robertson D, Cudkowicz ME, Biaggioni I, O'Donnell H, Zackert WE, Roberts LJ, Morrow JD. Cerebrospinal fluid F2-isoprostanes are elevated in Huntington's disease. Neurology. 1999 Mar 3/23/1999; 52(5): 1104-5. PMID: 10102447, ISSN: 0028-3878.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10102447.
  • Charles PD, Esper GJ, Davis TL, Maciunas RJ, Robertson D. Classification of tremor and update on treatment. Am Fam Physician. 1999 Mar 3/15/1999; 59(6): 1565-72. PMID: 10193597, ISSN: 0002-838X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10193597.
  • Austin MT, Davis TL, Robertson D, Charles PD. Multiple system atrophy: clinical presentation and diagnosis. Tenn Med. 1999 Feb; 92(2): 55-7. PMID: 9932532, ISSN: 1088-6222.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9932532.
  • Robertson D. The epidemic of orthostatic tachycardia and orthostatic intolerance. Am. J. Med. Sci. 1999 Feb; 317(2): 75-7. PMID: 10037110, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10037110.
  • Jacob G, Atkinson D, Jordan J, Shannon JR, Furlan R, Black BK, Robertson D. Effects of standing on cerebrovascular resistance in patients with idiopathic orthostatic intolerance. Am J Med. 1999; 106: 59-64.
  • Jacob G, Shannon JR, Costa F, Furlan R, Biaggioni I, Mosqueda-Garcia R, Robertson RM, Robertson D. Abnormal norepinephrine clearance and adrenergic receptor sensitivity in idiopathic orthostatic intolerance. Circulation. 1999; 99: 1706-12.
  • Jordan J, Shannon JR, Pohar B, Paranjape S, Robertson D, Robertson RM, Biaggioni I. Contrasting effects of vasodilators on blood pressure and sodium balance in the hypertension of autonomic failure. J Am Soc Nephrol. 1999; 10: 35-42.
  • Montine TJ, Beal MF, Robertson D, Cudkowicz ME, Biaggioni I, O'Donnell H, Zackert WE, Roberts LJ, Morrow JD. Cerebrospinal fluid F2-isoprostanes are elevated in Huntington's disease. Neurology. 1999; 52: 1104-5.
  • Shannon JR, Gottesdiener K, Jordan J, Chen K, Flattery S, Larson PJ, Candelore MR, Gertz B, Robertson D, Sun M. Acute effect of ephedrine on 24-h energy balance. Clin Sci. 1999; 96: 483-91.
  • Furlan R, Jacob G, Snell M, Robertson D, Porta A, Harris P, Mosqueda-Garcia R. Chronic orthostatic intolerance: a disorder with discordant cardiac and vascular sympathetic control. Circulation. 1998 Nov 11/17/1998; 98(20): 2154-9. PMID: 9815870, ISSN: 0009-7322.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9815870.
  • Choy AM, Lang CC, Roden DM, Robertson D, Wood AJ, Robertson RM, Biaggioni I. Abnormalities of the QT interval in primary disorders of autonomic failure. Am. Heart J. 1998 Oct; 136(4 Pt 1): 664-71. PMID: 9778070, PII: S0002870398000726, ISSN: 0002-8703.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9778070.
  • Shannon JR, Jordan J, Black BK, Costa F, Robertson D. Uncoupling of the baroreflex by N(N)-cholinergic blockade in dissecting the components of cardiovascular regulation. Hypertension. 1998 Jul; 32(1): 101-7. PMID: 9674645, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9674645.
  • Costa F, Biaggioni I. Role of nitric oxide in adenosine-induced vasodilation in humans. Hypertension. 1998 May; 31(5): 1061-4. PMID: 9576114, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9576114.
  • Jordan J, Shannon JR, Black BK, Lance RH, Squillante MD, Costa F, Robertson D. N(N)-nicotinic blockade as an acute human model of autonomic failure. Hypertension. 1998 May; 31(5): 1178-84. PMID: 9576132, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9576132.
  • Robertson D, DesJardin JA, Lichtenstein MJ. Distribution and observed associations of orthostatic blood pressure changes in elderly general medicine outpatients. Am. J. Med. Sci. 1998 May; 315(5): 287-95. PMID: 9587084, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9587084.
  • Jacob G, Ertl AC, Shannon JR, Furlan R, Robertson RM, Robertson D. Effect of standing on neurohumoral responses and plasma volume in healthy subjects. J. Appl. Physiol. 1998 Mar; 84(3): 914-21. PMID: 9480952, ISSN: 8750-7587.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9480952.
  • Jacob G, Biaggioni I, Mosqueda-Garcia R, Robertson RM, Robertson D. Relation of blood volume and blood pressure in orthostatic intolerance. Am. J. Med. Sci. 1998 Feb; 315(2): 95-100. PMID: 9472908, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9472908.
  • Biaggioni I, Costa F, Kaufmann H. Vestibular influences on autonomic cardiovascular control in humans. J Vestib Res. 1998 Jan; 8(1): 35-41. PMID: 9416587, PII: S0957427197000335, ISSN: 0957-4271.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9416587.
  • Shannon JR, Jordan J, Robertson D. Blood pressure in autonomic failure: drinks, meals and other ordeals. Clin. Sci. 1998 Jan; 94(1): 5. PMID: 9505860, ISSN: 0143-5221.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9505860.
  • Choy AMJ, Lang CC, Roden DM, Robertson D, Wood AJJ, Robertson RM, Biaggioni I. Abnormalities of the QT interval in primary disorders of autonomic failure. Am Heart J. 1998; 136: 664-71.
  • Jacob G, Ertl AC, Shannon JR, Furlan R, Robertson RM, Robertson D. The effect of standing on neurohumoral responses and plasma volume in healthy subjects. J Appl Physiol. 1998; 84: 914-21.
  • Jordan J, Shannon JR, Black BK, Lance RH, Squillante MD, Costa F, Robertson D. NN-nicotinic blockade as an acute human model of autonomic failure. Hypertension. 1998; 31: 1178-84.
  • Jordan J, Shannon JR, Black BK, Paranjape SY, Barwise J, Robertson D. Raised cerebrovascular resistance in idiopathic orthostatic intolerance: evidence for sympathetic vasoconstriction. Hypertension. 1998; 32: 699-704.
  • Robertson D, Hale N. Genetic diseases of hypotension. Adv. Pharmacol. 1998; 42: 61-5. PMID: 9327847, ISSN: 1054-3589.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9327847.
  • Shannon JR, Jordan J, Black BK, Costa F, Robertson D. Uncoupling of the baroreflex by NN-cholinergic blockade in dissecting the components of cardiovascular regulation. Hypertension. 1998; 32: 101-7.
  • Jordan J, Shannon JR, Black BK, Costa F, Ertl AC, Furlan R, Biaggioni I, Robertson D. Malignant vagotonia due to selective baroreflex failure. Hypertension. 1997 Nov; 30(5): 1072-7. PMID: 9369258, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9369258.
  • Shannon J, Jordan J, Costa F, Robertson RM, Biaggioni I. The hypertension of autonomic failure and its treatment. Hypertension. 1997 Nov; 30(5): 1062-7. PMID: 9369256, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9369256.
  • Jacob G, Robertson D, Mosqueda-Garcia R, Ertl AC, Robertson RM, Biaggioni I. Hypovolemia in syncope and orthostatic intolerance role of the renin-angiotensin system. Am. J. Med. 1997 Aug; 103(2): 128-33. PMID: 9274896, PII: S0002934397001332, ISSN: 0002-9343.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9274896.
  • Jacob G, Shannon JR, Black B, Biaggioni I, Mosqueda-Garcia R, Robertson RM, Robertson D. Effects of volume loading and pressor agents in idiopathic orthostatic tachycardia. Circulation. 1997 Jul 7/15/1997; 96(2): 575-80. PMID: 9244228, ISSN: 0009-7322.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9244228.
  • Charles PD, Maciunas RJ, Davis TL, Drowota FR, Truett AA, Giles JT, Cheney JT, Robertson D. Thalamic stimulation: an innovative treatment for tremor. Tenn Med. 1997 Jul; 90(7): 275-7. PMID: 9216239, ISSN: 1088-6222.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9216239.
  • Mosqueda-Garcia R, Furlan R, Fernandez-Violante R, Desai T, Snell M, Jarai Z, Ananthram V, Robertson RM, Robertson D. Sympathetic and baroreceptor reflex function in neurally mediated syncope evoked by tilt. J. Clin. Invest. 1997 Jun 6/1/1997; 99(11): 2736-44. PMID: 9169504, PMCID: PMC508120, DOI: 10.1172/JCI119463, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9169504.
  • Robertson D. The role of clinical pharmacology in molecular genetics. Int J Clin Pharmacol Ther. 1997 Apr; 35(4): 135-41. PMID: 9112133, ISSN: 0946-1965.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9112133.
  • Esper GJ, Charles PD, Davis TL, Robertson D. Adult-onset focal dystonias: presentation and treatment options. Tenn Med. 1997 Jan; 90(1): 18-20. PMID: 8997156, ISSN: 1088-6222.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8997156.
  • Fritz JD, Utz AL, Hale NM, Wu L, Powers AC, Verdoorn TA, Robertson D. Gene-based neurotransmitter modulation in cerebellar granule neurons. J. Neurochem. 1997 Jan; 68(1): 204-12. PMID: 8978727, ISSN: 0022-3042.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8978727.
  • Fritz JD, Utz AL, Hale NM, Wu L, Powers AC, Verdoorn TA, Robertson D. Gene-based neurotransmitter modulation in cerebellar granule neurons. J Neurochem. 1997; 68: 204-12.
  • Jacob G, Robertson D, Mosqueda-Garcia R, Ertl AC, Robertson RM, Biaggioni I. Hypovolemia in syncope and orthostatic intolerance. Role of the renin-angiotensin system. Am J Med. 1997; 103: 128.
  • Jacob G, Shannon JR, Black B, Biaggioni I, Mosqueda-Garcia R, Robertson RM, Robertson D. Effects of volume loading and pressor agents in idiopathic orthostatic tachycardia. Circulation. 1997; 96: 575-80.
  • Jordan J, Shannon JR, Black B, Costa F, Ertl AC, Furlan R, Biaggioni I, Robertson D. Malignant vagotonia due to selective baroreflex failure. Hypertension. 1997; 30: 1072-7.
  • Mosqueda-Garcia R, Furlan R, Fernandez-Violante R, Desai T, Snell M, Jarai Z, Ananthram V, Robertson RM,Robertson D. Sympathetic and baroreflex function in neurally-mediated syncope evoked by tilt. J Clin Invest. 1997; 99: 2736-44.
  • Shannon JR, Robertson D. Orthostatic hypotension. Curr Ther Endocrinol Metab. 1997; 6: 197-203. PMID: 9174737, ISSN: 0831-652X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9174737.
  • Wrenn CC, Picklo MJ, Lappi DA, Robertson D, Wiley RG. Central noradrenergic lesioning using anti-DBH-saporin: anatomical findings. Brain Res. 1996 Nov 11/18/1996; 740(1-2): 175-84. PMID: 8973812, PII: S0006-8993(96)00855-4, ISSN: 0006-8993.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8973812.
  • Fritz JD, Robertson D. Gene targeting approaches to the autonomic nervous system. J. Auton. Nerv. Syst. 1996 Oct 10/7/1996; 61(1): 1-5. PMID: 8912247, PII: S0165183896000550, ISSN: 0165-1838.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8912247.
  • Robertson D, Jacob G, Ertl A, Shannon J, Mosqueda-Garcia R, Robertson RM, Biaggioni I. Clinical models of cardiovascular regulation after weightlessness. Med Sci Sports Exerc. 1996 Oct; 28(10 Suppl): S80-4. PMID: 8897409, ISSN: 0195-9131.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8897409.
  • Holt JT, Arteaga CB, Robertson D, Moses HL. Gene therapy for the treatment of metastatic breast cancer by in vivo transduction with breast-targeted retroviral vector expressing antisense c-fos RNA. Hum. Gene Ther. 1996 Jul 7/10/1996; 7(11): 1367-80. PMID: 8818724, DOI: 10.1089/hum.1996.7.11-1367, ISSN: 1043-0342.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8818724.
  • Picklo MJ, Wiley RG, Lonce S, Lappi DA, Robertson D. Anti-dopamine beta-hydroxylase immunotoxin-induced sympathectomy in adult rats. J. Pharmacol. Exp. Ther. 1995 Nov; 275(2): 1003-10. PMID: 7473126, ISSN: 0022-3565.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7473126.
  • Costa F, Lavin P, Robertson D, Biaggioni I. Effect of neurovestibular stimulation on autonomic regulation. Clin. Auton. Res. 1995 Oct; 5(5): 289-93. PMID: 8563462, ISSN: 0959-9851.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8563462.
  • Jacob G, Robertson D. Orthostatic hypotension: epidemiology, pathophysiology and management. Curr. Opin. Nephrol. Hypertens. 1995 Sep; 4(5): 452-4. PMID: 8564451, ISSN: 1062-4821.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8564451.
  • Mitsky V, Robertson D. Failure of the autonomic nervous system. Compr Ther. 1995 Sep; 21(9): 529-34. PMID: 8565442, ISSN: 0098-8243.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8565442.
  • Charles PD, Davis TL, Robertson D, Fenichel GM. Dystonia and unique muscle features. A 23-year follow-up and correction of diagnosis in two brothers. Arch. Neurol. 1995 Aug; 52(8): 825-6. PMID: 7639635, ISSN: 0003-9942.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7639635.
  • Carey EL, Robertson D, Wells JN, Robertson RM. Contraction of isolated porcine coronary arteries is inhibited by high concentrations of propranolol. Angiology. 1995 Jun; 46(6): 453-60. PMID: 7785786, ISSN: 0003-3197.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7785786.
  • Robertson D, Davis TL. Recent advances in the treatment of orthostatic hypotension. Neurology. 1995 Apr; 45(4 Suppl 5): S26-32. PMID: 7746370, ISSN: 0028-3878.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7746370.
  • Netterville JL, Reilly KM, Robertson D, Reiber ME, Armstrong WB, Childs P. Carotid body tumors: a review of 30 patients with 46 tumors. Laryngoscope. 1995 Feb; 105(2): 115-26. PMID: 8544589, DOI: 10.1288/00005537-199502000-00002, ISSN: 0023-852X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8544589.
  • Robertson D. Diagnosis and management of baroreflex failure. Primary Cardiol. 1995 Jan; 21(1): 37-40, 44. PMID: 11541912, ISSN: 0363-5104.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11541912.
  • Picklo MJ, Wiley RG, Lappi DA, Robertson D. Noradrenergic lesioning with an anti-dopamine beta-hydroxylase immunotoxin. Brain Res. 1994 Dec 12/15/1994; 666(2): 195-200. PMID: 7882029, PII: 0006-8993(94)90772-2, ISSN: 0006-8993.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7882029.
  • Mitsky VP, Workman RJ, Nicholson WE, Vernikos J, Robertson RM, Robertson D. A sensitive radioimmunoassay for fludrocortisone in human plasma. Steroids. 1994 Sep; 59(9): 555-8. PMID: 7846738, PII: 0039-128X(94)90074-4, ISSN: 0039-128X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7846738.
  • Biaggioni I, Robertson D, Krantz S, Jones M, Haile V. The anemia of primary autonomic failure and its reversal with recombinant erythropoietin. Ann. Intern. Med. 1994 Aug 8/1/1994; 121(3): 181-6. PMID: 8017744, ISSN: 0003-4819.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8017744.
  • Robertson D, Convertino VA, Vernikos J. The sympathetic nervous system and the physiologic consequences of spaceflight: a hypothesis. Am. J. Med. Sci. 1994 Aug; 308(2): 126-32. PMID: 8042655, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8042655.
  • Robertson D, Robertson RM. Causes of chronic orthostatic hypotension. Arch. Intern. Med. 1994 Jul 7/25/1994; 154(14): 1620-4. PMID: 8031210, ISSN: 0003-9926.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8031210.
  • Robertson D, Krantz SB, Biaggioni I. The anemia of microgravity and recumbency: role of sympathetic neural control of erythropoietin production. Acta Astronaut. 1994 Jul; 33: 137-41. PMID: 11539513, ISSN: 0094-5765.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11539513.
  • Robertson D, Kincaid DW, Haile V, Robertson RM. The head and neck discomfort of autonomic failure: an unrecognized aetiology of headache. Clin. Auton. Res. 1994 Jun; 4(3): 99-103. PMID: 7994169, ISSN: 0959-9851.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7994169.
  • Biaggioni I, Robertson RM, Robertson D. Manipulation of norepinephrine metabolism with yohimbine in the treatment of autonomic failure. J Clin Pharmacol. 1994 May; 34(5): 418-23. PMID: 8089252, ISSN: 0091-2700.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8089252.
  • Appalsamy M, Robertson D, Mosqueda-Garcia R. Inhibition by ethanol of the cardiovascular effects of glutamate in the nucleus of the solitary tract. Am. J. Med. Sci. 1994 Feb; 307(2): 133-7. PMID: 7908166, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7908166.
  • Robertson D. Genetics and molecular biology of hypotension. Curr. Opin. Nephrol. Hypertens. 1994 Jan; 3(1): 13-24. PMID: 7850407, ISSN: 1062-4821.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7850407.
  • Robertson D, Hollister AS, Biaggioni I, Netterville JL, Mosqueda-Garcia R, Robertson RM. The diagnosis and treatment of baroreflex failure. N. Engl. J. Med. 1993 Nov 11/11/1993; 329(20): 1449-55. PMID: 8413455, DOI: 10.1056/NEJM199311113292003, ISSN: 0028-4793.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8413455.
  • Robertson D. Autonomic neuropharmacology. Curr Opin Neurol Neurosurg. 1993 Aug; 6(4): 527-30. PMID: 8104552, ISSN: 0951-7383.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8104552.
  • Robertson D, Beck C, Gary T, Picklo M. Classification of autonomic disorders. Int Angiol. 1993 Jun; 12(2): 93-102. PMID: 8371002, ISSN: 0392-9590.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8371002.
  • Tseng CJ, Appalsamy M, Robertson D, Mosqueda-Garcia R. Effects of nicotine on brain stem mechanisms of cardiovascular control. J. Pharmacol. Exp. Ther. 1993 Jun; 265(3): 1511-8. PMID: 8099622, ISSN: 0022-3565.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8099622.
  • Hamakubo T, Furuta H, Ichimura M, Appalsamy M, Mosqueda-Garcia R, Robertson D, Inagami T. A Na pump inhibitor from bovine posterior pituitary: purification, structure determination and its cardiovascular effect in rat. Biochem. Biophys. Res. Commun. 1992 Dec 12/15/1992; 189(2): 691-6. PMID: 1335244, PII: 0006-291X(92)92256-W, ISSN: 0006-291X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1335244.
  • Robertson D, Biaggioni I, Mosqueda-Garcia R, Robertson RM. Orthostatic hypotension of prolonged weightlessness: clinical models. Acta Astronaut. 1992 Jul; 27: 97-101. PMID: 11537606, ISSN: 0094-5765.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11537606.
  • Robertson D, Mosqueda-Garcia R, Robertson RM, Biaggioni I. Chronic hypotension. In the shadow of hypertension. Am. J. Hypertens. 1992 Jun; 5(6 Pt 2): 200S-205S. PMID: 1632940, ISSN: 0895-7061.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1632940.
  • Robertson D, Cavalcante JW. [Orthostatic hypotension]. Arq. Bras. Cardiol. 1992 Apr; 58(4): 255-61. PMID: 1340693, ISSN: 0066-782X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1340693.
  • Robertson RM, Biaggioni I, Mosqueda-Garcia R, Robertson D. Autonomic dysfunction: diagnosis guided by therapy. Trans. Am. Clin. Climatol. Assoc. 1992; 103: 228-37. PMID: 1413383, PMCID: PMC2376695, ISSN: 0065-7778.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1413383.
  • Mosqueda-Garcia R, Tseng CJ, Appalsamy M, Beck C, Robertson D. Cardiovascular excitatory effects of adenosine in the nucleus of the solitary tract. Hypertension. 1991 Oct; 18(4): 494-502. PMID: 1680812, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1680812.
  • Robertson D. Role of the General Clinical Research Center in teaching clinical management. J Clin Pharmacol. 1991 Aug; 31(8): 691-6. PMID: 1880228, ISSN: 0091-2700.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1880228.
  • Robertson D, Haile V, Perry SE, Robertson RM, Phillips JA, Biaggioni I. Dopamine beta-hydroxylase deficiency. A genetic disorder of cardiovascular regulation. Hypertension. 1991 Jul; 18(1): 1-8. PMID: 1677640, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1677640.
  • Perry SE, Summar ML, Phillips JA, Robertson D. Linkage analysis of the human dopamine beta-hydroxylase gene. Genomics. 1991 Jun; 10(2): 493-5. PMID: 2071155, PII: 0888-7543(91)90339-G, ISSN: 0888-7543.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2071155.
  • Mosqueda-Garcia R, Oates JA, Appalsamy M, Robertson D. Administration of carbamazepine in the nucleus of the solitary tract inhibits the antihypertensive effect of clonidine. Eur. J. Pharmacol. 1991 May 5/17/1991; 197(2-3): 213-6. PMID: 1915569, PII: 0014-2999(91)90524-T, ISSN: 0014-2999.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1915569.
  • Biaggioni I, Killian TJ, Mosqueda-Garcia R, Robertson RM, Robertson D. Adenosine increases sympathetic nerve traffic in humans. Circulation. 1991 May; 83(5): 1668-75. PMID: 2022024, ISSN: 0009-7322.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2022024.
  • Onrot J, Bernard GR, Biaggioni I, Hollister AS, Robertson D. Direct vasodilator effect of hyperventilation-induced hypocarbia in autonomic failure patients. Am. J. Med. Sci. 1991 May; 301(5): 305-9. PMID: 1902350, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1902350.
  • Perry SE, Phillips JA, Robertson D. FnuD II RFLP at the human dopamine-beta-hydroxylase (D beta H) locus. Nucleic Acids Res. 1991 Mar 3/11/1991; 19(5): 1162. PMID: 1673558, PMCID: PMC333814, ISSN: 0305-1048.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1673558.
  • Mosqueda-Garcia R, Tseng CJ, Biaggioni I, Robertson RM, Robertson D. Effects of caffeine on baroreflex activity in humans. Clin. Pharmacol. Ther. 1990 Nov; 48(5): 568-74. PMID: 2225715, PII: 0009-9236(90)90099-Q, ISSN: 0009-9236.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2225715.
  • Mosqueda-Garcia R, Tseng CJ, Appalsamy M, Robertson D. Cardiovascular effects of microinjection of angiotensin II in the brainstem of renal hypertensive rats. J. Pharmacol. Exp. Ther. 1990 Oct; 255(1): 374-81. PMID: 2213569, ISSN: 0022-3565.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2213569.
  • Paul S, Feoktistov I, Hollister AS, Robertson D, Biaggioni I. Adenosine inhibits the rise in intracellular calcium and platelet aggregation produced by thrombin: evidence that both effects are coupled to adenylate cyclase. Mol. Pharmacol. 1990 Jun; 37(6): 870-5. PMID: 2359405, ISSN: 0026-895X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2359405.
  • Kronenberg MW, Forman MB, Onrot J, Robertson D. Enhanced left ventricular contractility in autonomic failure: assessment using pressure-volume relations. J. Am. Coll. Cardiol. 1990 May; 15(6): 1334-42. PMID: 2158505, ISSN: 0735-1097.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2158505.
  • Biaggioni I, Goldstein DS, Atkinson T, Robertson D. Dopamine-beta-hydroxylase deficiency in humans. Neurology. 1990 Feb; 40(2): 370-3. PMID: 2300263, ISSN: 0028-3878.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2300263.
  • Biaggioni I, Zygmunt D, Haile V, Robertson D. Pressor effect of inhaled ergotamine in orthostatic hypotension. Am. J. Cardiol. 1990 Jan 1/1/1990; 65(1): 89-92. PMID: 2104735, PII: 0002-9149(90)90031-U, ISSN: 0002-9149.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2104735.
  • Mosqueda-Garcia R, Tseng CJ, Appalsamy M, Robertson D. Modulatory effects of adenosine on baroreflex activation in the brainstem of normotensive rats. Eur. J. Pharmacol. 1989 Dec 12/12/1989; 174(1): 119-22. PMID: 2612574, ISSN: 0014-2999.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2612574.
  • Biaggioni I, King LS, Enayat N, Robertson D, Newman JH. Adenosine produces pulmonary vasoconstriction in sheep. Evidence for thromboxane A2/prostaglandin endoperoxide-receptor activation. Circ. Res. 1989 Dec; 65(6): 1516-25. PMID: 2582587, ISSN: 0009-7330.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2582587.
  • Paul S, Jackson EK, Robertson D, Branch RA, Biaggioni I. Caffeine potentiates the renin response to furosemide in rats. Evidence for a regulatory role of endogenous adenosine. J. Pharmacol. Exp. Ther. 1989 Oct; 251(1): 183-7. PMID: 2677316, ISSN: 0022-3565.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2677316.
  • Tseng CJ, Mosqueda-Garcia R, Appalsamy M, Robertson D. Cardiovascular effects of neuropeptide Y in rat brainstem nuclei. Circ. Res. 1989 Jan; 64(1): 55-61. PMID: 2909302, ISSN: 0009-7330.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2909302.
  • Biaggioni I, Paul S, Robertson D. A simple liquid-chromatographic method applied to determine caffeine in plasma and tissues. Clin. Chem. 1988 Nov; 34(11): 2345-8. PMID: 3180432, ISSN: 0009-9147.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/3180432.
  • Bottiglieri DF, Robertson D, Jackson EK. A comparison of nucleoside transport and metabolism in hypertensive and normotensive rats. Hypertension. 1988 Aug; 12(2): 102-7. PMID: 3410521, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/3410521.
  • Paul S, Zygmunt D, Haile V, Robertson D, Biaggioni I. Chronic orthostatic hypotension. Compr Ther. 1988 Aug; 14(8): 58-65. PMID: 3048866, ISSN: 0098-8243.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/3048866.
  • Tseng CJ, Robertson D, Light RT, Atkinson JR, Robertson RM. Neuropeptide Y is a vasoconstrictor of human coronary arteries. Am. J. Med. Sci. 1988 Jul; 296(1): 11-6. PMID: 3407677, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/3407677.
  • Tseng CJ, Biaggioni I, Appalsamy M, Robertson D. Purinergic receptors in the brainstem mediate hypotension and bradycardia. Hypertension. 1988 Feb; 11(2): 191-7. PMID: 3277913, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/3277913.
  • Robertson D, Tseng CJ, Appalsamy M. Smoking and mechanisms of cardiovascular control. Am. Heart J. 1988 Jan; 115(1 Pt 2): 258-63. PMID: 3276114, ISSN: 0002-8703.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/3276114.
  • Biaggioni I, Olafsson B, Robertson RM, Hollister AS, Robertson D. Cardiovascular and respiratory effects of adenosine in conscious man. Evidence for chemoreceptor activation. Circ. Res. 1987 Dec; 61(6): 779-86. PMID: 3677336, ISSN: 0009-7330.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/3677336.
  • Biaggioni I, Robertson D. Endogenous restoration of noradrenaline by precursor therapy in dopamine-beta-hydroxylase deficiency. Lancet. 1987 Nov 11/21/1987; 2(8569): 1170-2. PMID: 2890806, PII: S0140-6736(87)91317-1, ISSN: 0140-6736.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2890806.
  • Onrot J, Wiley RG, Fogo A, Biaggioni I, Robertson D, Hollister AS. Neck tumour with syncope due to paroxysmal sympathetic withdrawal. J. Neurol. Neurosurg. Psychiatr. 1987 Aug; 50(8): 1063-6. PMID: 3655815, PMCID: PMC1032240, ISSN: 0022-3050.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/3655815.
  • Scott HW, Dean RH, Lea JW, Waterhouse G, Sussman C, Robertson D, Oates JA. Surgical experience with retrogastric and retropancreatic pheochromocytomas. Surgery. 1982 Nov; 92(5): 853-65. PMID: 6753206, ISSN: 0039-6060.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/6753206.
  • Scott HW, Reynolds V, Green N, Page D, Oates JA, Robertson D, Roberts S. Clinical experience with malignant pheochromocytomas. Surg Gynecol Obstet. 1982 Jun; 154(6): 801-18. PMID: 7079921, ISSN: 0039-6087.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7079921.
  • Keller N, Diedrich A, Appalsamy M, Tuntrakool S, Lonce S, Finney C, Caron M, Robertson D.. Norepinephrine transporter-deficient mice exhibit excessive tachycardia and elevated blood pressure with wakefulness and activity. Circulation. 110: 1191-6.