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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center


Donna J. Webb, Ph.D.

Assistant Professor of Biological Sciences
Assistant Professor of Cancer Biology

Contact Information:

Vanderbilt University Medical Center
U6211 MRBIII, 465 21st Av S.
Nashville, TN 37232
Fax: 615-343-6707

Research Specialty

Signal Transduction Pathways that Regulate Adhesion and Cytoskeletal Dynamics in Migration and Synapse Formation, Cell biology, Neurobiology

Research Description

My laboratory is interested in cell migration, which plays a pivotal role in many important phenomena including cancer, mental retardation and embryonic development. We are studying the signaling pathways that regulate adhesion and cytoskeletal dynamics in a variety of normal and cancer cells since this could lead to new targets for the development of anti-cancer therapeutics. A special focus in my lab is understanding the signaling pathways that regulate the formation of dendritic spines and synapses in the central nervous system. The dynamics of these spines is an exciting frontier in neuroscience because it contributes to synaptic plasticity, which underlies cognitive functions, such as learning and memory.