Vanderbilt-Ingram Cancer Center

Publications

• Gresch, PJ, Barrett, RJ, Sanders-Bush, E, Smith, RL 5-Hydroxytryptamine (serotonin)2A receptors in rat anterior cingulate cortex mediate the discriminative stimulus properties of d-lysergic acid diethylamide. J Pharmacol Exp Ther, 320(2), 662-9, 2007.
• Hackler, EA, Turner, GH, Gresch, PJ, Sengupta, S, Deutch, AY, Avison, MJ, Gore, JC, Sanders-Bush, E 5-Hydroxytryptamine2C Receptor Contribution to m-Chlorophenylpiperazine and N-Methyl-beta-carboline-3-carboxamide-Induced Anxiety-Like Behavior and Limbic Brain Activation. J Pharmacol Exp Ther, 320(3), 1023-9, 2007.
• Benneyworth, MA, Xiang, Z, Smith, RL, Garcia, EE, Conn, PJ, Sanders-Bush, E A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis. Mol Pharmacol, 72(2), 477-84, 2007.
• Muldowney, JA, Painter, CA, Sanders-Bush, E, Brown, NJ, Vaughan, DE Acute tissue-type plasminogen activator release in human microvascular endothelial cells: The roles of Galpha(q), PLC-beta, IP(3) and 5,6-epoxyeicosatrienoic acid. Thromb Haemost, 97(2), 263-71, 2007.
• Myers, RL, Airey, DC, Manier, DH, Shelton, RC, Sanders-Bush, E Polymorphisms in the regulatory region of the human serotonin 5-HT2A receptor gene (HTR2A) influence gene expression. Biol Psychiatry, 61(2), 167-73, 2007.
• Garcia, EE, Smith, RL, Sanders-Bush, E Role of G(q) protein in behavioral effects of the hallucinogenic drug 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane. Neuropharmacology, 52(8), 1671-7, 2007.
• Hackler, EA, Airey, DC, Shannon, CC, Sodhi, MS, Sanders-Bush, E 5-HT(2C) receptor RNA editing in the amygdala of C57BL/6J, DBA/2J, and BALB/cJ mice. Neurosci Res, 55(1), 96-104, 2006.
• Tomlinson, ID, Gies, AP, Gresch, PJ, Dillard, J, Orndorff, RL, Sanders-Bush, E, Hercules, DM, Rosenthal, SJ Universal polyethylene glycol linkers for attaching receptor ligands to quantum dots. Bioorg Med Chem Lett, 16(24), 6262-6, 2006.
• Sodhi, MS, Airey, DC, Lambert, W, Burnet, PW, Harrison, PJ, Sanders-Bush, E A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts. Mol Pharmacol, 68(3), 711-9, 2005.
• Gresch, PJ, Smith, RL, Barrett, RJ, Sanders-Bush, E Behavioral tolerance to lysergic acid diethylamide is associated with reduced serotonin-2A receptor signaling in rat cortex. Neuropsychopharmacology, 30(9), 1693-702, 2005.
• Benneyworth, Michael, Smith, Randy, Barrett, Robert, Sanders-Bush, Elaine Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice. Psychopharmacology (Berl), 2005.
• Fentress, HM, Grinde, E, Mazurkiewicz, JE, Backstrom, JR, Herrick-Davis, K, Sanders-Bush, E Pharmacological properties of the Cys23Ser single nucleotide polymorphism in human 5-HT2C receptor isoforms. Pharmacogenomics J, 5(4), 244-54, 2005.
• Akin, Demet, Hal Manier, D, Sanders-Bush, Elaine, Shelton, Richard C Signal transduction abnormalities in melancholic depression. Int J Neuropsychopharmacol, 8(1), 5-16, 2005.
• Bentzen, EL, Tomlinson, ID, Mason, J, Gresch, P, Warnement, MR, Wright, D, Sanders-Bush, E, Blakely, R, Rosenthal, SJ Surface modification to reduce nonspecific binding of quantum dots in live cell assays. Bioconjug Chem, 16(6), 1488-94, 2005.
• Akin, Demet, Manier, D Hal, Sanders-Bush, Elaine, Shelton, Richard C Decreased serotonin 5-HT2A receptor-stimulated phosphoinositide signaling in fibroblasts from melancholic depressed patients. Neuropsychopharmacology, 29(11), 2081-7, 2004.
• Hazelwood, Lisa A, Sanders-Bush, Elaine His452Tyr polymorphism in the human 5-HT2A receptor destabilizes the signaling conformation. Mol Pharmacol, 66(5), 1293-300, 2004.
• Nichols, Charles D, Sanders-Bush, Elaine Molecular genetic responses to lysergic acid diethylamide include transcriptional activation of MAP kinase phosphatase-1, C/EBP-beta and ILAD-1, a novel gene with homology to arrestins. J Neurochem, 90(3), 576-84, 2004.
• McGrew, Lori, Price, Raymond D, Hackler, Elizabeth, Chang, Mike S S, Sanders-Bush, Elaine RNA editing of the human serotonin 5-HT2C receptor disrupts transactivation of the small G-protein RhoA. Mol Pharmacol, 65(1), 252-6, 2004.
• Sodhi, Monsheel S K, Sanders-Bush, Elaine Serotonin and brain development. Int Rev Neurobiol, 59111-74, 2004.
• Parker, Lisan L, Backstrom, Jon R, Sanders-Bush, Elaine, Shieh, Bih-Hwa Agonist-induced phosphorylation of the serotonin 5-HT2C receptor regulates its interaction with multiple PDZ protein 1. J Biol Chem, 278(24), 21576-83, 2003.
• Smith, Randy L, Barrett, Robert J, Sanders-Bush, Elaine Discriminative stimulus properties of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane [(+/-)DOI] in C57BL/6J mice. Psychopharmacology (Berl), 166(1), 61-8, 2003.
• Nichols, Charles D, Garcia, Efrain E, Sanders-Bush, Elaine Dynamic changes in prefrontal cortex gene expression following lysergic acid diethylamide administration. Brain Res Mol Brain Res, 111(1-2), 182-8, 2003.
• Sanders-Bush, Elaine, Fentress, Hugh, Hazelwood, Lisa Serotonin 5-ht2 receptors: molecular and genomic diversity. Mol Intervent, 3(6), 319-30, 2003.
• Miner, L A H, Backstrom, J R, Sanders-Bush, E, Sesack, S R Ultrastructural localization of serotonin2A receptors in the middle layers of the rat prelimbic prefrontal cortex. Neuroscience, 116(1), 107-17, 2003.
• Nichols, Charles D, Sanders-Bush, Elaine A single dose of lysergic acid diethylamide influences gene expression patterns within the mammalian brain. Neuropsychopharmacology, 26(5), 634-42, 2002.
• Nichols, C D, Ronesi, J, Pratt, W, Sanders-Bush, E Hallucinogens and Drosophila: linking serotonin receptor activation to behavior. Neuroscience, 115(3), 979-84, 2002.
• Gresch, P J, Strickland, L V, Sanders-Bush, E Lysergic acid diethylamide-induced Fos expression in rat brain: role of serotonin-2A receptors. Neuroscience, 114(3), 707-13, 2002.
• McGrew, L, Chang, M S S, Sanders-Bush, E Phospholipase D activation by endogenous 5-hydroxytryptamine 2C receptors is mediated by Galpha13 and pertussis toxin-insensitive Gbetagamma subunits. Mol Pharmacol, 62(6), 1339-43, 2002.
• Smith, Randy L, Gresch, Paul J, Barrett, Robert J, Sanders-Bush, Elaine Stimulus generalization by fenfluramine in a quipazine-ketanserin drug discrimination is not dependent on indirect serotonin release. Pharmacol Biochem Behav, 72(1-2), 77-85, 2002.
• Bubser, M, Backstrom, J R, Sanders-Bush, E, Roth, B L, Deutch, A Y Distribution of serotonin 5-HT(2A) receptors in afferents of the rat striatum. Synapse, 39(4), 297-304, 2001.
• Peavy, R D, Chang, M S, Sanders-Bush, E, Conn, P J Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor. J Neurosci, 21(24), 9619-28, 2001.
• Price, R D, Weiner, D M, Chang, M S, Sanders-Bush, E RNA editing of the human serotonin 5-HT2C receptor alters receptor-mediated activation of G13 protein. J Biol Chem, 276(48), 44663-8, 2001.
• Niswender, C M, Herrick-Davis, K, Dilley, G E, Meltzer, H Y, Overholser, J C, Stockmeier, C A, Emeson, R B, Sanders-Bush, E RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy. Neuropsychopharmacology, 24(5), 478-91, 2001.
• Berg, K A, Cropper, J D, Niswender, C M, Sanders-Bush, E, Emeson, R B, Clarke, W P RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity. Br J Pharmacol, 134(2), 386-92, 2001.
• Backstrom, J R, Price, R D, Reasoner, D T, Sanders-Bush, E Deletion of the serotonin 5-HT2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responses. J Biol Chem, 275(31), 23620-6, 2000.
• Chang, M, Zhang, L, Tam, J P, Sanders-Bush, E Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells. J Biol Chem, 275(10), 7021-9, 2000.
• Chang, M S, Tam, J P, Sanders-Bush, E Dissecting intracellular signaling pathways with membrane-permeable peptides. Sci STKE, 2000(47), PL1, 2000.
• Price, R D, Sanders-Bush, E RNA editing of the human serotonin 5-HT(2C) receptor delays agonist-stimulated calcium release. Mol Pharmacol, 58(4), 859-62, 2000.
• Bancila, M, Vergé, D, Rampin, O, Backstrom, J R, Sanders-Bush, E, McKenna, K E, Marson, L, Calas, A, Giuliano, F 5-Hydroxytryptamine2C receptors on spinal neurons controlling penile erection in the rat. Neuroscience, 92(4), 1523-37, 1999.
• Backstrom, J R, Chang, M S, Chu, H, Niswender, C M, Sanders-Bush, E Agonist-Directed Signaling of Serotonin 5-HT(2C) Receptors: Differences Between Serotonin and Lysergic Acid Diethylamide (LSD). Neuropsychopharmacology, 21 Suppl 1S77-81, 1999.
• Backstrom, J R, Chang, M S, Chu, H, Niswender, C M, Sanders-Bush, E Agonist-directed signaling of serotonin 5-HT2C receptors: differences between serotonin and lysergic acid diethylamide (LSD). Neuropsychopharmacology, 21(2 Suppl), 77S-81S, 1999.
• Willins, D L, Berry, S A, Alsayegh, L, Backstrom, J R, Sanders-Bush, E, Friedman, L, Roth, B L Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo. Neuroscience, 91(2), 599-606, 1999.
• Grotewiel, M S, Sanders-Bush, E Differences in agonist-independent activity of 5-Ht2A and 5-HT2c receptors revealed by heterologous expression. Naunyn Schmiedebergs Arch Pharmacol, 359(1), 21-7, 1999.
• Smith, R L, Barrett, R J, Sanders-Bush, E Mechanism of tolerance development to 2,5-dimethoxy-4-iodoamphetamine in rats: down-regulation of the 5-HT2A, but not 5-HT2C, receptor. Psychopharmacology (Berl), 144(3), 248-54, 1999.
• Niswender, C M, Copeland, S C, Herrick-Davis, K, Emeson, R B, Sanders-Bush, E RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity. J Biol Chem, 274(14), 9472-8, 1999.
• Smith, R L, Canton, H, Barrett, R J, Sanders-Bush, E Agonist properties of N,N-dimethyltryptamine at serotonin 5-HT2A and 5-HT2C receptors. Pharmacol Biochem Behav, 61(3), 323-30, 1998.
• Seifert, R, Wenzel-Seifert, K, Lee, T W, Gether, U, Sanders-Bush, E, Kobilka, B K Different effects of Gsalpha splice variants on beta2-adrenoreceptor-mediated signaling. The Beta2-adrenoreceptor coupled to the long splice variant of Gsalpha has properties of a constitutively active receptor. J Biol Chem, 273(18), 5109-16, 1998.
• Seifert, R, Wenzel-Seifert, K, Lee, T W, Gether, U, Sanders-Bush, E, Kobilka, B K Different effects of Gsalpha splice variants on beta2-adrenoreceptor-mediated signaling. The beta2-adrenoreceptor coupled to the long splice variant of Gsalpha has properties of a constitutively active receptor. J Biol Chem, 273(9), 5109-16, 1998.
• Niswender, C M, Sanders-Bush, E, Emeson, R B Identification and characterization of RNA editing events within the 5-HT2C receptor. Ann N Y Acad Sci, 86138-48, 1998.
• Willins, D L, Alsayegh, L, Berry, S A, Backstrom, J R, Sanders-Bush, E, Friedman, L, Khan, N, Roth, B L Serotonergic antagonist effects on trafficking of serotonin 5-HT2A receptors in vitro and in vivo. Ann N Y Acad Sci, 861121-7, 1998.
• Monte, A P, Waldman, S R, Marona-Lewicka, D, Wainscott, D B, Nelson, D L, Sanders-Bush, E, Nichols, D E Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives. J Med Chem, 40(19), 2997-3008, 1997.
• Backstrom, J R, Sanders-Bush, E Generation of anti-peptide antibodies against serotonin 5-HT2A and 5-HT2C receptors. J Neurosci Methods, 77(1), 109-17, 1997.
• Burns, C M, Chu, H, Rueter, S M, Hutchinson, L K, Canton, H, Sanders-Bush, E, Emeson, R B Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature, 387(6630), 303-8, 1997.
• Gether, U, Ballesteros, J A, Seifert, R, Sanders-Bush, E, Weinstein, H, Kobilka, B K Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility. J Biol Chem, 272(5), 2587-90, 1997.
• Westphal, R S, Sanders-Bush, E Differences in agonist-independent and -dependent 5-hydroxytryptamine2C receptor-mediated cell division. Mol Pharmacol, 49(3), 474-80, 1996.
• Canton, H, Emeson, R B, Barker, E L, Backstrom, J R, Lu, J T, Chang, M S, Sanders-Bush, E Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing. Mol Pharmacol, 50(4), 799-807, 1996.
• Onaivi, E S, Bishop-Robinson, C, Darmani, N A, Sanders-Bush, E Behavioral effects of (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, (DOI) in the elevated plus-maze test. Life Sci, 57(26), 2455-66, 1995.
• Ike, J, Canton, H, Sanders-Bush, E Developmental switch in the hippocampal serotonin receptor linked to phosphoinositide hydrolysis. Brain Res, 678(1-2), 49-54, 1995.
• Backstrom, J R, Westphal, R S, Canton, H, Sanders-Bush, E Identification of rat serotonin 5-HT2C receptors as glycoproteins containing N-linked oligosaccharides. Brain Res Mol Brain Res, 33(2), 311-8, 1995.
• Westphal, R S, Backstrom, J R, Sanders-Bush, E Increased basal phosphorylation of the constitutively active serotonin 2C receptor accompanies agonist-mediated desensitization. Mol Pharmacol, 48(2), 200-5, 1995.
• Smith, R L, Barrett, R J, Sanders-Bush, E Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor. J Pharmacol Exp Ther, 275(2), 1050-7, 1995.
• Sanders-Bush E, Canton H "Serotonin receptors: Signal transduction pathways." Psychopharmacology: Fourth Generation of Progress, 1995.
• Monte, A P, Marona-Lewicka, D, Kanthasamy, A, Sanders-Bush, E, Nichols, D E Stereoselective LSD-like activity in a series of d-lysergic acid amides of (R)- and (S)-2-aminoalkanes. J Med Chem, 38(6), 958-66, 1995.
• Mayer, S E, Sanders-Bush, E 5-Hydroxytryptamine type 2A and 2C receptors linked to Na+/K+/Cl- cotransport. Mol Pharmacol, 45(5), 991-6, 1994.
• Barker, E L, Westphal, R S, Schmidt, D, Sanders-Bush, E Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands. J Biol Chem, 269(16), 11687-90, 1994.
• Sanders-Bush, E Neurochemical evidence that hallucinogenic drugs are 5-HT1c receptor agonists: what next. NIDA Res Monogr, 146203-13, 1994.
• Westphal, R S, Sanders-Bush, E Reciprocal binding properties of 5-hydroxytryptamine type 2C receptor agonists and inverse agonists. Mol Pharmacol, 46(5), 937-42, 1994.
• Grotewiel, M S, Sanders-Bush, E Regulation of serotonin2A receptors in heterologous expression systems. J Neurochem, 63(4), 1255-60, 1994.
• Grotewiel, M S, Chu, H, Sanders-Bush, E m-chlorophenylpiperazine and m-trifluoromethylphenylpiperazine are partial agonists at cloned 5-HT2A receptors expressed in fibroblasts. J Pharmacol Exp Ther, 271(2), 1122-6, 1994.
• Barker, E L, Sanders-Bush, E 5-hydroxytryptamine1C receptor density and mRNA levels in choroid plexus epithelial cells after treatment with mianserin and (-)-1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. Mol Pharmacol, 44(4), 725-30, 1993.
• Mayer, S E, Sanders-Bush, E Sodium-dependent antiporters in choroid plexus epithelial cultures from rabbit. J Neurochem, 60(4), 1308-16, 1993.
• Glennon, R A, Teitler, M, Sanders-Bush, E Hallucinogens and serotonergic mechanisms. NIDA Res Monogr, 119131-5, 1992.
• Esterle, T M, Sanders-Bush, E Serotonin agonists increase transferrin levels via activation of 5-HT1C receptors in choroid plexus epithelium. J Neurosci, 12(12), 4775-82, 1992.
• Burris, K D, Sanders-Bush, E Unsurmountable antagonism of brain 5-hydroxytryptamine2 receptors by (+)-lysergic acid diethylamide and bromo-lysergic acid diethylamide. Mol Pharmacol, 42(5), 826-30, 1992.
• Burris, K D, Breeding, M, Sanders-Bush, E (+)Lysergic acid diethylamide, but not its nonhallucinogenic congeners, is a potent serotonin 5HT1C receptor agonist. J Pharmacol Exp Ther, 258(3), 891-6, 1991.
• Sanders-Bush, E, Breeding, M Choroid plexus epithelial cells in primary culture: a model of 5HT1C receptor activation by hallucinogenic drugs. Psychopharmacology (Berl), 105(3), 340-6, 1991.
• Esterle, T M, Sanders-Bush, E From neurotransmitter to gene: identifying the missing links. Trends Pharmacol Sci, 12(10), 375-9, 1991.
• Barker, E L, Burris, K D, Sanders-Bush, E Phosphoinositide hydrolysis linked 5-HT2 receptors in fibroblasts from choroid plexus. Brain Res, 552(2), 330-2, 1991.
• Tsutsumi, M, Sanders-Bush, E 5-HT-induced transferrin production by choroid plexus epithelial cells in culture: role of 5-HT1c receptor. J Pharmacol Exp Ther, 254(1), 253-7, 1990.
• Smith, R L, Barrett, R J, Sanders-Bush, E Adaptation of brain 5HT2 receptors after mianserin treatment: receptor sensitivity, not receptor binding, more accurately correlates with behavior. J Pharmacol Exp Ther, 254(2), 484-8, 1990.
• Sanders-Bush, E Adaptive regulation of central serotonin receptors linked to phosphoinositide hydrolysis. Neuropsychopharmacology, 3(5-6), 411-6, 1990.
• Sanders-Bush, E, Tsutsumi, M, Burris, K D Serotonin receptors and phosphatidylinositol turnover. Ann N Y Acad Sci, 600224-35; discussion 235-6, 1990.
• Sanders-Bush, E, Breeding, M Serotonin1c receptor reserve in choroid plexus masks receptor subsensitivity. J Pharmacol Exp Ther, 252(3), 984-8, 1990.
• Sanders-Bush, E, Breeding, M, Knoth, K, Tsutsumi, M Sertraline-induced desensitization of the serotonin 5HT-2 receptor transmembrane signaling system. Psychopharmacology (Berl), 99(1), 64-9, 1989.
• Tsutsumi, M, Skinner, M K, Sanders-Bush, E Transferrin gene expression and synthesis by cultured choroid plexus epithelial cells. Regulation by serotonin and cyclic adenosine 3',5'-monophosphate. J Biol Chem, 264(16), 9626-31, 1989.
• Sanders-Bush, E, Burris, K D, Knoth, K Lysergic acid diethylamide and 2,5-dimethoxy-4-methylamphetamine are partial agonists at serotonin receptors linked to phosphoinositide hydrolysis. J Pharmacol Exp Ther, 246(3), 924-8, 1988.
• Sanders-Bush, E, Breeding, M Putative selective 5-HT-2 antagonists block serotonin 5-HT-1c receptors in the choroid plexus. J Pharmacol Exp Ther, 247(1), 169-73, 1988.
• Gillespie, D D, Manier, D H, Sanders-Bush, E, Sulser, F The serotonin/norepinephrine-link in brain. II. Role of serotonin in the regulation of beta adrenoceptors in the low agonist affinity conformation. J Pharmacol Exp Ther, 244(1), 154-9, 1988.
• Sanders-Bush, E, Breeding, M, Roznoski, M 5HT2 binding sites after mianserin: comparison of loss of sites and brain levels of drug. Eur J Pharmacol, 133(2), 199-204, 1987.
• Conn, P J, Sanders-Bush, E Central serotonin receptors: effector systems, physiological roles and regulation. Psychopharmacology (Berl), 92(3), 267-77, 1987.
• Conn, P J, Janowsky, A, Sanders-Bush, E Denervation supersensitivity of 5-HT-1c receptors in rat choroid plexus. Brain Res, 400(2), 396-8, 1987.
• Conn, P J, Sanders-Bush, E Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors. J Pharmacol Exp Ther, 242(2), 552-7, 1987.
• Sulser, F, Sanders-Bush, E The serotonin-norepinephrine link hypothesis of affective disorders: receptor-receptor interactions in brain. Adv Exp Med Biol, 221489-502, 1987.
• Manier, D H, Gillespie, D D, Sanders-Bush, E, Sulser, F The serotonin/noradrenaline-link in brain. I. The role of noradrenaline and serotonin in the regulation of density and function of beta adrenoceptors and its alteration by desipramine. Naunyn Schmiedebergs Arch Pharmacol, 335(2), 109-14, 1987.
• Conn, P J, Sanders-Bush, E, Hoffman, B J, Hartig, P R A unique serotonin receptor in choroid plexus is linked to phosphatidylinositol turnover. Proc Natl Acad Sci U S A, 83(11), 4086-8, 1986.
• Blackshear, M A, Martin, L L, Sanders-Bush, E Adaptive changes in the 5-HT2 binding site after chronic administration of agonists and antagonists. Neuropharmacology, 25(11), 1267-71, 1986.
• Conn, P J, Sanders-Bush, E Agonist-induced phosphoinositide hydrolysis in choroid plexus. J Neurochem, 47(6), 1754-60, 1986.
• Conn, P J, Sanders-Bush, E Biochemical characterization of serotonin stimulated phosphoinositide turnover. Life Sci, 38(7), 663-9, 1986.
• Sanders-Bush, E, Conn, P J Effector systems coupled to serotonin receptors in brain: serotonin stimulated phosphoinositide hydrolysis. Psychopharmacol Bull, 22(3), 829-36, 1986.
• Conn, P J, Sanders-Bush, E Regulation of serotonin-stimulated phosphoinositide hydrolysis: relation to the serotonin 5-HT-2 binding site. J Neurosci, 6(12), 3669-75, 1986.
• Conn, P J, Sanders-Bush, E Serotonin-stimulated phosphoinositide turnover: mediation by the S2 binding site in rat cerebral cortex but not in subcortical regions. J Pharmacol Exp Ther, 234(1), 195-203, 1985.
• Sanders-Bush, E, Conn, J, Sulser, F The serotonin/norepinephrine-linked beta-adrenoceptor system and the mode of action of antidepressants. Psychopharmacol Bull, 21(3), 373-8, 1985.
• Friedman, R L, Sanders-Bush, E, Barrett, R L Clozapine blocks disruptive and discriminative stimulus effects of quipazine. Eur J Pharmacol, 106(1), 191-3, 1984.
• Friedman, R L, Barrett, R J, Sanders-Bush, E Discriminative stimulus properties of quipazine: mediation by serotonin2 binding sites. J Pharmacol Exp Ther, 228(3), 628-35, 1984.
• Conn, P J, Sanders-Bush, E Selective 5HT-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex. Neuropharmacology, 23(8), 993-6, 1984.
• Blackshear, M A, Friedman, R L, Sanders-Bush, E Acute and chronic effects of serotonin (5HT) antagonists on serotonin binding sites. Naunyn Schmiedebergs Arch Pharmacol, 324(2), 125-9, 1983.
• Friedman, R, Barrett, R J, Sanders-Bush, E Additional evidence that L-5-hydroxytryptophan discrimination models a unique serotonin receptor. Psychopharmacology (Berl), 80(3), 209-13, 1983.
• Martin, L L, Sanders-Bush, E Comparison of the pharmacological characteristics of 5 HT1 and 5 HT2 binding sites with those of serotonin autoreceptors which modulate serotonin release. Naunyn Schmiedebergs Arch Pharmacol, 321(3), 165-70, 1982.
• Barrett, R J, Blackshear, M A, Sanders-Bush, E Discriminative stimulus properties of L-5-hydroxytryptophan: behavioral evidence for multiple serotonin receptors. Psychopharmacology (Berl), 76(1), 29-35, 1982.
• Sanders-Bush, E Regulation of serotonin storage and release. Adv Biochem Psychopharmacol, 3417-34, 1982.
• Blackshear, M A, Sanders-Bush, E Serotonin receptor sensitivity after acute and chronic treatment with mianserin. J Pharmacol Exp Ther, 221(2), 303-8, 1982.
• Martin, L L, Sanders-Bush, E The serotonin autoreceptor: antagonism by quipazine. Neuropharmacology, 21(5), 445-50, 1982.
• Blackshear, M A, Steranka, L R, Sanders-Bush, E Multiple serotonin receptors: regional distribution and effect of Raphe lesions. Eur J Pharmacol, 76(4), 325-34, 1981.
• Bush, M T, Sanders-Bush, E Diazomethane: improved analytical and distillation techniques for small quantities and some synthetic applications. Anal Biochem, 106(2), 351-62, 1980.
• Steranka, L R, Sanders-Bush, E Long-term effects of continuous exposure to amphetamine on brain dopamine concentration and synaptosomal uptake in mice. Eur J Pharmacol, 65(4), 439-43, 1980.
• Steranka, L R, Sanders-Bush, E Long-term effects of fenfluramine on central serotonergic mechanisms. Neuropharmacology, 18(11), 895-903, 1979.
• Mobley, P L, Sanders-Bush, E, Smith, H E, Sulser, F Modification of the noradrenergic cyclic AMP generating system in the rat limbic forebrain by amphetamine: role of its hydroxylated metabolites. Naunyn Schmiedebergs Arch Pharmacol, 306(3), 267-73, 1979.
• Steranka, L R, Sanders-Bush, E Species differences in the rate of disappearance of fenfluramine and its effects on brain serotonin neurons. Biochem Pharmacol, 28(20), 3103-7, 1979.
• Massari, V J, Tizabi, Y, Sanders-Bush, E Evaluation of the neurotoxic effects of p-chloroamphetamine: a histological and biochemical study. Neuropharmacology, 17(7), 541-8, 1978.
• Sanders-Bush, E, Steranka, L R Immediate and long-term effects of p-chloroamphetamine on brain amines. Ann N Y Acad Sci, 305208-21, 1978.
• Steranka, L R, Sanders-Bush, E Long-term effects of continuous exposure to p-chloroamphetamine on central serotonergic mechanisms in mice. Biochem Pharmacol, 27(16), 2033-7, 1978.
• Steranka, L R, Sanders-Bush, E Long-term reduction of brain serotonin by p-chloroamphetamine: effects of inducers and inhibitors of drug metabolism. J Pharmacol Exp Ther, 206(2), 460-7, 1978.
• Sanders-Bush, E, Massari, V J Actions of drugs that deplete serotonin. Fed Proc, 36(8), 2149-53, 1977.
• Steranka, L R, Barrett, R J, Sanders-Bush, E Facilitation of Sidman avoidance performance by p-chloroamphetamine: role of biogenic amines. Neuropharmacology, 16(11), 751-9, 1977.
• El-Yousef, M K, Steranka, L, Sanders-Bush, E Rapid tolerance to the motor effects of p-chloroamphetamine in rats. Psychopharmacology (Berl), 55(2), 109-14, 1977.
• Steranka, L, Bessent, R, Sanders-Bush, E Reversible and irreversible effects of p-chloroamphetamine on brain serotonin in mice. Commun Psychopharmacol, 1(5), 447-54, 1977.
• Steranka, L, Sanders-Bush, E Temporal effects of p-chloroamphetamine on catecholamine synthesis. Eur J Pharmacol, 45(1), 83-6, 1977.
• Steranka, L R, Sanders-Bush, E, Barrett, R J Tolerance to p-chloroamphetamines effects on Sidman avoidance performance and catecholamine metabolism. Neuropharmacology, 16(11), 761-9, 1977.
• Sanders-Bush, E Long-term effects of para-chloroamphetamine on central serotonergic mechanisms. Psychopharmacol Bull, 12(3), 57-9, 1976.
• Sanders-Bush, E, Oates, J A, Bush, M T Metabolism of bufotenine-2'-14C in human volunteers. Life Sci, 19(9), 1407-11, 1976.
• Gallager, D W, Sanders-Bush, E, Aghajanian, G K, Sulser, F An evaluation of the use of intraventricularly administered [3H]5-hydroxytryptamine as a marker for endogenous brain 5-hydroxytryptamine. Brain Res, 93(1), 111-22, 1975.
• Sekerke, H J, Smith, H E, Bushing, J A, Sanders-Bush, E Correlation between brain levels and biochemical effects of the optical isomers of p-chloroamphetamine. J Pharmacol Exp Ther, 193(3), 835-44, 1975.
• Sanders-Bush, E, Bushing, J A, Sulser, F Long-term effects of p-chloroamphetamine and related drugs on central serotonergic mechanisms. J Pharmacol Exp Ther, 192(1), 33-41, 1975.
• Massari, V J, Sanders-Bush, E Synaptosomal uptake and levels of serotonin in rat brain areas after p-chloroamphetamine or B-9 lesions. Eur J Pharmacol, 33(2), 419-22, 1975.
• Smith, H E, Burrows, E P, Miano, J D, Mount, C D, Sanders-Bush, E, Sulser, F Action of (S)-and(R)-para-substituted amphetamine hydrochlorides and (alphaS)-and (alphaR)-p-chloronorephedrine and (alphaS)-and (alphaR)-p-chloronorpseudoephedrine hydrochlorides on the level of 5-hydroxytryptamine and the activity of tryptophan hydroxylase in rat brain. J Med Chem, 17(4), 416-21, 1974.
• Sanders-Bush, E, Gallager, D A, Sulser, F On the mechanism of brain 5-hydroxytryptamine depletion by p-chloroamphetamine and related drugs and the specificity of their action. Adv Biochem Psychopharmacol, 10185-94, 1974.
• Schaefer, G J, Barrett, R J, Sanders-Bush, E, Vorhees, C V p-Chloroamphetamine: evidence against a serotonin mediated learning deficit in PKU. Pharmacol Biochem Behav, 2(6), 783-9, 1974.
• Yarbrough, G G, Buxbaum, D M, Sanders-Bush, E Biogenic amines and narcotic effects. II. Serotonin turnover in the rat after acute and chronic morphine administration. J Pharmacol Exp Ther, 185(2), 328-35, 1973.
• Gallager, D W, Sanders-Bush, E, Sulser, F Dissociation between behavioral effects and changes in metabolism of cerebral serotonin following 9 -tetrahydrocannabinol. Psychopharmacologia, 26(4), 337-45, 1972.
• Sanders-Bush, E, Bushing, J A, Sulser, F Long-term effects of p-chloroamphetamine on tryptophan hydroxylase activity and on the levels of 5-hydroxytryptamine and 5-hydroxyindole acetic acid in brain. Eur J Pharmacol, 20(3), 385-8, 1972.
• Sanders-Bush, E, Bushing, J A, Sulser, F p-Chloroamphetamine--inhibition of cerebral tryptophan hydroxylase. Biochem Pharmacol, 21(10), 1501-10, 1972.
• Sulser, F, Sanders-Bush, E Effect of drugs on amines in the CNS. Annu Rev Pharmacol, 11209-30, 1971.
• Yarbrough, G G, Buxbaum, D M, Sanders-Bush, E Increased serotonin turnover in the acutely morphine treated rat. Life Sci I, 10(17), 977-83, 1971.
• Schmidt, M J, Sanders-Bush, E Tryptophan hydroxylase activity in developing rat brain. J Neurochem, 18(12), 2549-51, 1971.
• Miller, K W, Sanders-Bush, E, Dingell, J V p-Chloramphetamine--species differences in the rate of disappearance and the lowering of cerebral serotonin. Biochem Pharmacol, 20(2), 500-3, 1971.
• Sanders-Bush, E, Sulser, F P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin. J Pharmacol Exp Ther, 175(2), 419-26, 1970.
• Strada, S J, Sanders-Bush, E, Sulser, F p-Chloroamphetamine. Temporal relationship between psychomotor stimulation and metabolism of brain norepinephrine. Biochem Pharmacol, 19(9), 2621-9, 1970.