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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center


Elaine Sanders-Bush, Ph.D.

Professor of Pharmacology and Psychiatry, Emerita

Contact Information:

Vanderbilt University Medical Center
461 Preston Building
Nashville, TN 37232-6600

Research Specialty

Function and regulation of specific serotonin receptor subtypes in the brain

Research Description

Two members of the 5-HT2 family of serotonin receptors (5-HT2A and 5-HT2C receptors) are implicated in the control of physiological processes such as cognition, appetite and mood and in the action of antipsychotic and hallucinogenic drugs. Our studies combine multidisciplinary approaches ranging from molecular biology to animal behavior to define the mechanisms of normal and abnormal regulation of the structure and function of these G protein-coupled receptors.