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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center

 
Eric  Shinohara

Eric Shinohara, M.D., MSCI

Associate Professor
Medical Director, Department of Radiation Oncology
Radiation Oncologist

  • Appointments
    615-322-2555
    Physicians: 1-877-936-8422
  • Clinical Trials Information
  • Other Telephone Numbers
    Gateway-Vanderbilt Cancer Treatment Center
    (931) 221-0479

    Vanderbilt-Ingram Cancer Center at Franklin
    (615) 591-9890

    Vanderbilt-Ingram Cancer Center Radiation Oncology
    (615) 322-2555

    Vanderbilt-Ingram Cancer Center at Maury Regional Spring Hill
    (931) 380-1194

  • Faxes
    Gateway-Vanderbilt Cancer Treatment Center Fax
    (931) 221-3280
    Vanderbilt-Ingram Cancer Center at Franklin Fax
    (615) 591-5899
    Vanderbilt-Ingram Cancer Center Radiation Oncology Fax
    (615) 343-3075

    Clinic Fax
    615-936-3363
  • Addresses
    Clinic
    The Vanderbilt Clinic (TVC) - Preston Research Building
    Department of Radiation Oncology, B1003
    1301 22nd Ave., South
    Nashville, TN 37232-5671

    Gateway-Vanderbilt Cancer Treatment Center
    375 Alfred Thun Road
    Clarksville, TN 37040
    Website

    Vanderbilt-Ingram Cancer Center at Franklin
    2107 Edward Curd Lane
    Franklin, TN 37067
    Website

    Vanderbilt-Ingram Cancer Center Radiation Oncology
    22nd at Pierce Avenue, B1034
    Nashville, TN 37232-5671
    Website

    Vanderbilt-Ingram Cancer Center at Maury Regional Spring Hill
    1003 Reserve Boulevard
    Spring Hill, TN 37174
    Website

Profile

Dr. Shinohara joined the Vanderbilt-Ingram Cancer Center as Assistant Professor in 2010. He received a B.S. in Physiology and Neurobiology as well as a B.A .in Japanese from the University of Maryland. He received his M.D. degree in 2003 from Vanderbilt University School of Medicine and went on to receive a M.
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Dr. Shinohara joined the Vanderbilt-Ingram Cancer Center as Assistant Professor in 2010. He received a B.S. in Physiology and Neurobiology as well as a B.A .in Japanese from the University of Maryland. He received his M.D. degree in 2003 from Vanderbilt University School of Medicine and went on to receive a M.S. in Clinical Investigation in 2005. He completed his residency in radiation oncology at the Hospital of the University of Pennsylvania in 2010.

Honors/AwardsASTRO Travel Award-51st Annual MeetingMethods in Clinical Cancer Research -ECCO-AACR-ASCO Workshop Flims,SwitzerlandASTRO Travel Award - Advances in Technology: Practical Aspects on IMRT and Proton Therapy SymposiumRoentgen Resident/Fellow Research Award - Radiological Society of North America (RSNA)ASCO Foundation Merit Award -GI SymposiumIntern of the Year -Abington Memorial HospitalMicrobes and Defense Academic Society -Vanderbilt University School of MedicinePhi Beta Kappa Honor Society - University of MarylandMortar Board National Honor Society - University of MarylandGolden Key National Honor Society - University of MarylandCollege Park Scholars Program - University of Maryland

Education
  • Residency-Hospital of the University of Pennsylvania-Philadelphia, PA
  • Internship-Abington Memorial Hospital-Abington, PA
  • Master of Science-Vanderbilt University School of Medicine-Nashville, TN
  • Medical Doctorate-Vanderbilt University School of Medicine-Nashville, TN
  • Bachelor of Science-University of Maryland-College Park, MD
Publications
  • Shinohara ET, Guo M, Mitra N, Metz JM. Brachytherapy in the treatment of cholangiocarcinoma. Int. J. Radiat. Oncol. Biol. Phys [print-electronic]. 2010 Nov 11/1/2010; 78(3): 722-8. PMID: 20207503, PII: S0360-3016(09)03044-2, DOI: 10.1016/j.ijrobp.2009.08.070, ISSN: 1879-355X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20207503.
  • Fernandes AT, Shinohara ET, Guo M, Mitra N, Wilson LD, Rengan R, Metz JM. The role of radiation therapy in malignant thymoma: a Surveillance, Epidemiology, and End Results database analysis. J Thorac Oncol. 2010 Sep; 5(9): 1454-60. PMID: 20651611, DOI: 10.1097/JTO.0b013e3181e8f345, ISSN: 1556-1380.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20651611.
  • Shinohara ET, Maity A. Increasing sensitivity to radiotherapy and chemotherapy by using novel biological agents that alter the tumor microenvironment. Curr. Mol. Med. 2009 Dec; 9(9): 1034-45. PMID: 19938317, ISSN: 1875-5666.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19938317.
  • Shinohara ET, Mitra N, Guo M, Metz JM. Radiotherapy is associated with improved survival in adjuvant and palliative treatment of extrahepatic cholangiocarcinomas. Int. J. Radiat. Oncol. Biol. Phys [print-electronic]. 2009 Jul 7/15/2009; 74(4): 1191-8. PMID: 19201549, PII: S0360-3016(08)03469-X, DOI: 10.1016/j.ijrobp.2008.09.017, ISSN: 1879-355X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19201549.
  • Shinohara ET, Maity A, Jha N, Lustig RA. Sirolimus as a potential radiosensitizer in squamous cell cancer of the head and neck. Head Neck. 2009 Mar; 31(3): 406-11. PMID: 18704962, PMCID: PMC2737255, DOI: 10.1002/hed.20898, ISSN: 1097-0347.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18704962.
  • Shinohara ET, Mitra N, Guo M, Metz JM. Radiation therapy is associated with improved survival in the adjuvant and definitive treatment of intrahepatic cholangiocarcinoma. Int. J. Radiat. Oncol. Biol. Phys [print-electronic]. 2008 Dec 12/1/2008; 72(5): 1495-501. PMID: 18472359, PII: S0360-3016(08)00480-X, DOI: 10.1016/j.ijrobp.2008.03.018, ISSN: 1879-355X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18472359.
  • Jaboin JJ, Shinohara ET, Moretti L, Yang ES, Kaminski JM, Lu B. The role of mTOR inhibition in augmenting radiation induced autophagy. Technol. Cancer Res. Treat. 2007 Oct; 6(5): 443-7. PMID: 17877432, PII: d=3029&c=4241&p=16188&do=detail, ISSN: 1533-0346.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17877432.
  • Shinohara ET, Kaminski JM, Segal DJ, Pelczar P, Kolhe R, Ryan T, Coates CJ, Fraser MJ, Handler AM, Yanagimachi R, Moisyadi S. Active integration: new strategies for transgenesis. Transgenic Res [print-electronic]. 2007 Jun; 16(3): 333-9. PMID: 17340207, DOI: 10.1007/s11248-007-9077-z, ISSN: 0962-8819.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17340207.
  • Kim KW, Mutter RW, Willey CD, Subhawong TK, Shinohara ET, Albert JM, Ling G, Cao C, Gi YJ, Lu B. Inhibition of survivin and aurora B kinase sensitizes mesothelioma cells by enhancing mitotic arrests. Int. J. Radiat. Oncol. Biol. Phys. 2007 Apr 4/1/2007; 67(5): 1519-25. PMID: 17394948, PII: S0360-3016(06)03665-0, DOI: 10.1016/j.ijrobp.2006.12.018, ISSN: 0360-3016.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17394948.
  • Shinohara ET, Gonzalez A, Massion PP, Olson SJ, Albert JM, Shyr Y, Carbone DP, Johnson DH, Hallahan DE, Lu B. PDGFR-beta expression in small cell lung cancer patients. Int. J. Radiat. Oncol. Biol. Phys. 2007 Feb 2/1/2007; 67(2): 431-7. PMID: 17236966, PII: S0360-3016(06)02807-0, DOI: 10.1016/j.ijrobp.2006.08.060, ISSN: 0360-3016.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17236966.
  • Shinohara ET, Swisher-McClure S, Husson M, Sun W, Metz JM. Esophageal cancer in a young woman with bulimia nervosa: a case report. J Med Case Rep. 2007; 1: 160. PMID: 18047676, PMCID: PMC2213673, PII: 1752-1947-1-160, DOI: 10.1186/1752-1947-1-160, ISSN: 1752-1947.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18047676.
  • Yazlovitskaya EM, Edwards E, Thotala D, Fu A, Osusky KL, Whetsell WO, Boone B, Shinohara ET, Hallahan DE. Lithium treatment prevents neurocognitive deficit resulting from cranial irradiation. Cancer Res. 2006 Dec 12/1/2006; 66(23): 11179-86. PMID: 17145862, PII: 66/23/11179, DOI: 10.1158/0008-5472.CAN-06-2740, ISSN: 0008-5472.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17145862.
  • Kim KW, Mutter RW, Cao C, Albert JM, Shinohara ET, Sekhar KR, Lu B. Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of Survivin following irradiation. Mol. Cancer Ther. 2006 Nov; 5(11): 2659-65. PMID: 17121912, PII: 5/11/2659, DOI: 10.1158/1535-7163.MCT-06-0261, ISSN: 1535-7163.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17121912.
  • Li HC, Albert JM, Shinohara ET, Cai Q, Freyer A, Cai H, Cao C, Wang Z, Kataoka N, Teng M, Zheng W, Lu B. E-cadherin promoter polymorphisms are not associated with the aggressiveness of prostate cancer in Caucasian patients. Urol. Oncol. 2006 Nov; 24(6): 496-502. PMID: 17138130, PII: S1078-1439(06)00062-7, DOI: 10.1016/j.urolonc.2006.02.018, ISSN: 1078-1439.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17138130.
  • Browning RE, Li H, Shinohara ET, Cai Q, Chen H, Courtney R, Cao C, Zheng W, Lu B. ATM polymorphism IVS62+60G>A is not associated with disease aggressiveness in prostate cancer. Urology. 2006 Jun; 67(6): 1320-3. PMID: 16765197, PII: S0090-4295(05)01766-8, DOI: 10.1016/j.urology.2005.12.012, ISSN: 1527-9995.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16765197.
  • Li H, Shinohara ET, Cai Q, Chen H, Courtney R, Cao C, Wang Z, Teng M, Zheng W, Lu B. Plasminogen activator inhibitor-1 promoter polymorphism is not associated with the aggressiveness of disease in prostate cancer. Clin Oncol (R Coll Radiol). 2006 May; 18(4): 333-7. PMID: 16703752, ISSN: 0936-6555.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16703752.
  • Cuneo KC, Geng L, Tan J, Brousal J, Shinohara ET, Osusky K, Fu A, Shyr Y, Wu H, Hallahan DE. SRC family kinase inhibitor SU6656 enhances antiangiogenic effect of irradiation. Int. J. Radiat. Oncol. Biol. Phys. 2006 Mar 3/15/2006; 64(4): 1197-203. PMID: 16504759, PII: S0360-3016(05)02974-3, DOI: 10.1016/j.ijrobp.2005.11.014, ISSN: 0360-3016.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16504759.
  • Cao C, Shinohara ET, Subhawong TK, Geng L, Kim KW, Albert JM, Hallahan DE, Lu B. Radiosensitization of lung cancer by nutlin, an inhibitor of murine double minute 2. Mol. Cancer Ther. 2006 Feb; 5(2): 411-7. PMID: 16505116, PII: 5/2/411, DOI: 10.1158/1535-7163.MCT-05-0356, ISSN: 1535-7163.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16505116.
  • Geng L, Shinohara ET, Kim D, Tan J, Osusky K, Shyr Y, Hallahan DE. STI571 (Gleevec) improves tumor growth delay and survival in irradiated mouse models of glioblastoma. Int. J. Radiat. Oncol. Biol. Phys [print-electronic]. 2006 Jan 1/1/2006; 64(1): 263-71. PMID: 16274936, PII: S0360-3016(05)02387-4, DOI: 10.1016/j.ijrobp.2005.08.025, ISSN: 0360-3016.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16274936.
  • Lu B, Shinohara ET, Edwards E, Geng L, Tan J, Hallahan DE. The use of tyrosine kinase inhibitors in modifying the response of tumor microvasculature to radiotherapy. Technol. Cancer Res. Treat. 2005 Dec; 4(6): 691-8. PMID: 16292890, PII: d=3022&c=4191&p=13211&do=detail, ISSN: 1533-0346.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16292890.
  • Cao C, Shinohara ET, Li H, Niermann KJ, Kim KW, Sekhar KR, Gleave M, Freeman M, Lu B. Clusterin as a therapeutic target for radiation sensitization in a lung cancer model. Int. J. Radiat. Oncol. Biol. Phys. 2005 Nov 11/15/2005; 63(4): 1228-36. PMID: 16253777, PII: S0360-3016(05)02143-7, DOI: 10.1016/j.ijrobp.2005.07.956, ISSN: 0360-3016.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16253777.
  • Cao C, Shinohara ET, Niermann KJ, Donnelly EF, Chen X, Hallahan DE, Lu B. Murine double minute 2 as a therapeutic target for radiation sensitization of lung cancer. Mol. Cancer Ther. 2005 Aug; 4(8): 1137-45. PMID: 16093429, PII: 4/8/1137, DOI: 10.1158/1535-7163.MCT-04-0327, ISSN: 1535-7163.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16093429.