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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center

 

Martha J. Shrubsole, Ph.D.

Research Associate Professor of Medicine (Epidemiology)
Cancer Epidemiologist

Contact Information:

Vanderbilt University Medical Center
2525 West End Ave, 8th floor
Nashville, Tn 37203-1738
615-936-0812
Fax: 615-936-8241

Research Description

My research interests are in the nutritional and molecular epidemiology of breast and colorectal tumors.

Publications
  • Han MR, Deming-Halverson S, Cai Q, Wen W, Shrubsole MJ, Shu XO, Zheng W, Long J. Evaluating 17 breast cancer susceptibility loci in the Nashville breast health study. Breast Cancer [print-electronic]. 2015 Sep; 22(5): 544-51. PMID: 24510657, PMCID: PMC4127164, DOI: 10.1007/s12282-014-0518-2, ISSN: 1880-4233.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24510657.
  • Lin WY, Camp NJ, Ghoussaini M, Beesley J, Michailidou K, Hopper JL, Apicella C, Southey MC, Stone J, Schmidt MK, Broeks A, Van't Veer LJ, Th Rutgers EJ, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Peto J, Dos-Santos-Silva I, Fletcher O, Johnson N, Bolla MK, Wang Q, Dennis J, Sawyer EJ, Cheng T, Tomlinson I, Kerin MJ, Miller N, Marmé F, Surowy HM, Burwinkel B, Guénel P, Truong T, Menegaux F, Mulot C, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Benitez J, Zamora MP, Arias Perez JI, Menéndez P, González-Neira A, Pita G, Alonso MR, Alvarez N, Herrero D, Anton-Culver H, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Meindl A, Lichtner P, Schmutzler RK, Müller-Myhsok B, Brauch H, Brüning T, Ko YD, , Tessier DC, Vincent D, Bacot F, Nevanlinna H, Aittomäki K, Blomqvist C, Khan S, Matsuo K, Ito H, Iwata H, Horio A, Bogdanova NV, Antonenkova NN, Dörk T, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, , , Wu AH, Tseng CC, Van Den Berg D, Stram DO, Neven P, Wauters E, Wildiers H, Lambrechts D, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Radice P, Peterlongo P, Manoukian S, Bonanni B, Couch FJ, Wang X, Vachon C, Purrington K, Giles GG, Milne RL, Mclean C, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Simard J, Goldberg MS, Labrèche F, Dumont M, Teo SH, Yip CH, Hassan N, Vithana EN, Kristensen V, Zheng W, Deming-Halverson S, Shrubsole MJ, Long J, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Kauppila S, Andrulis IL, Knight JA, Glendon G, Tchatchou S, Devilee P, Tollenaar RA, Seynaeve C, Van Asperen CJ, García-Closas M, Figueroa J, Lissowska J, Brinton L, Czene K, Darabi H, Eriksson M, Brand JS, Hooning MJ, Hollestelle A, Van Den Ouweland AM, Jager A, Li J, Liu J, Humphreys K, Shu XO, Lu W, Gao YT, Cai H, Cross SS, Reed MW, Blot W, Signorello LB, Cai Q, Pharoah PD, Perkins B, Shah M, Blows FM, Kang D, Yoo KY, Noh DY, Hartman M, Miao H, Chia KS, Putti TC, Hamann U, Luccarini C, Baynes C, Ahmed S, Maranian M, Healey CS, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Sangrajrang S, Gaborieau V, Brennan P, Mckay J, Slager S, Toland AE, Yannoukakos D, Shen CY, Hsiung CN, Wu PE, Ding SL, Ashworth A, Jones M, Orr N, Swerdlow AJ, Tsimiklis H, Makalic E, Schmidt DF, Bui QM, Chanock SJ, Hunter DJ, Hein R, Dahmen N, Beckmann L, Aaltonen K, Muranen TA, Heikkinen T, Irwanto A, Rahman N, Turnbull CA, , Waisfisz Q, Meijers-Heijboer HE, Adank MA, Van Der Luijt RB, Hall P, Chenevix-Trench G, Dunning A, Easton DF, Cox A. Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. Hum. Mol. Genet [print-electronic]. 2015 Jan 1/1/2015; 24(1): 285-98. PMID: 25168388, PMCID: PMC4334820, PII: ddu431, DOI: 10.1093/hmg/ddu431, ISSN: 1460-2083.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25168388.
  • Cui Y, Deming-Halverson SL, Shrubsole MJ, Beeghly-Fadiel A, Fair AM, Sanderson M, Shu XO, Kelley MC, Zheng W. Associations of hormone-related factors with breast cancer risk according to hormone receptor status among white and African American women. Clin. Breast Cancer [print-electronic]. 2014 Dec; 14(6): 417-25. PMID: 24970715, PMCID: PMC4253543, PII: S1526-8209(14)00085-8, DOI: 10.1016/j.clbc.2014.04.003, ISSN: 1938-0666.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24970715.
  • Milne RL, Burwinkel B, Michailidou K, Arias-Perez JI, Zamora MP, Menéndez-Rodríguez P, Hardisson D, Mendiola M, González-Neira A, Pita G, Alonso MR, Dennis J, Wang Q, Bolla MK, Swerdlow A, Ashworth A, Orr N, Schoemaker M, Ko YD, Brauch H, Hamann U, , Andrulis IL, Knight JA, Glendon G, Tchatchou S, , , Matsuo K, Ito H, Iwata H, Tajima K, Li J, Brand JS, Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, Lambrechts D, Peuteman G, Christiaens MR, Smeets A, Jakubowska A, Lubinski J, Jaworska-Bieniek K, Durda K, Hartman M, Hui M, Yen Lim W, Wan Chan C, Marme F, Yang R, Bugert P, Lindblom A, Margolin S, García-Closas M, Chanock SJ, Lissowska J, Figueroa JD, Bojesen SE, Nordestgaard BG, Flyger H, Hooning MJ, Kriege M, van den Ouweland AM, Koppert LB, Fletcher O, Johnson N, dos-Santos-Silva I, Peto J, Zheng W, Deming-Halverson S, Shrubsole MJ, Long J, Chang-Claude J, Rudolph A, Seibold P, Flesch-Janys D, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Cox A, Cross SS, Reed MW, Schmidt MK, Broeks A, Cornelissen S, Braaf L, Kang D, Choi JY, Park SK, Noh DY, Simard J, Dumont M, Goldberg MS, Labrèche F, Fasching PA, Hein A, Ekici AB, Beckmann MW, Radice P, Peterlongo P, Azzollini J, Barile M, Sawyer E, Tomlinson I, Kerin M, Miller N, Hopper JL, Schmidt DF, Makalic E, Southey MC, Hwang Teo S, Har Yip C, Sivanandan K, Tay WT, Shen CY, Hsiung CN, Yu JC, Hou MF, Guénel P, Truong T, Sanchez M, Mulot C, Blot W, Cai Q, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Bogdanova N, Dörk T, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Shu XO, Lu W, Gao YT, Zhang B, Couch FJ, Toland AE, , Yannoukakos D, Sangrajrang S, McKay J, Wang X, Olson JE, Vachon C, Purrington K, Severi G, Baglietto L, Haiman CA, Henderson BE, Schumacher F, Le Marchand L, Devilee P, Tollenaar RA, Seynaeve C, Czene K, Eriksson M, Humphreys K, Darabi H, Ahmed S, Shah M, Pharoah PD, Hall P, Giles GG, Benítez J, Dunning AM, Chenevix-Trench G, Easton DF. Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium. Hum. Mol. Genet [print-electronic]. 2014 Nov 11/15/2014; 23(22): 6096-111. PMID: 24943594, PMCID: PMC4204770, PII: ddu311, DOI: 10.1093/hmg/ddu311, ISSN: 1460-2083.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24943594.
  • Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, Winqvist R, Brenner H, Lindblom A, Chenevix-Trench G, Benitez J, Swerdlow A, Kristensen V, Guénel P, Meindl A, Darabi H, Eriksson M, Fagerholm R, Aittomäki K, Blomqvist C, Nordestgaard BG, Nielsen SF, Flyger H, Wang X, Olswold C, Olson JE, Mulligan AM, Knight JA, Tchatchou S, Reed MW, Cross SS, Liu J, Li J, Humphreys K, Clarke C, Scott R, , Fostira F, Fountzilas G, Konstantopoulou I, Henderson BE, Schumacher F, Le Marchand L, Ekici AB, Hartmann A, Beckmann MW, Hartikainen JM, Kosma VM, Kataja V, Jukkola-Vuorinen A, Pylkäs K, Kauppila S, Dieffenbach AK, Stegmaier C, Arndt V, Margolin S, , , Balleine R, Arias Perez JI, Pilar Zamora M, Menéndez P, Ashworth A, Jones M, Orr N, Arveux P, Kerbrat P, Truong T, Bugert P, Toland AE, Ambrosone CB, Labrèche F, Goldberg MS, Dumont M, Ziogas A, Lee E, Dite GS, Apicella C, Southey MC, Long J, Shrubsole M, Deming-Halverson S, Ficarazzi F, Barile M, Peterlongo P, Durda K, Jaworska-Bieniek K, Tollenaar RA, Seynaeve C, , Brüning T, Ko YD, Van Deurzen CH, Martens JW, Kriege M, Figueroa JD, Chanock SJ, Lissowska J, Tomlinson I, Kerin MJ, Miller N, Schneeweiss A, Tapper WJ, Gerty SM, Durcan L, Mclean C, Milne RL, Baglietto L, dos Santos Silva I, Fletcher O, Johnson N, Van'T Veer LJ, Cornelissen S, Försti A, Torres D, Rüdiger T, Rudolph A, Flesch-Janys D, Nickels S, Weltens C, Floris G, Moisse M, Dennis J, Wang Q, Dunning AM, Shah M, Brown J, Simard J, Anton-Culver H, Neuhausen SL, Hopper JL, Bogdanova N, Dörk T, Zheng W, Radice P, Jakubowska A, Lubinski J, Devillee P, Brauch H, Hooning M, García-Closas M, Sawyer E, Burwinkel B, Marmee F, Eccles DM, Giles GG, Peto J, Schmidt M, Broeks A, Hamann U, Chang-Claude J, Lambrechts D, Pharoah PD, Easton D, Pankratz VS, Slager S, Vachon CM, Couch FJ. Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade. Hum. Mol. Genet [print-electronic]. 2014 Nov 11/15/2014; 23(22): 6034-46. PMID: 24927736, PMCID: PMC4204763, PII: ddu300, DOI: 10.1093/hmg/ddu300, ISSN: 1460-2083.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24927736.
  • Takata Y, Shrubsole MJ, Li H, Cai Q, Gao J, Wagner C, Wu J, Zheng W, Xiang YB, Shu XO. Plasma folate concentrations and colorectal cancer risk: a case-control study nested within the Shanghai Men's Health Study. Int. J. Cancer [print-electronic]. 2014 Nov 11/1/2014; 135(9): 2191-8. PMID: 24692023, PMCID: PMC4134766, DOI: 10.1002/ijc.28871, ISSN: 1097-0215.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24692023.
  • Zhu X, Liang J, Shrubsole MJ, Ness RM, Cai Q, Long J, Chen Z, Li G, Wiese D, Zhang B, Smalley WE, Edwards TL, Giovannucci E, Zheng W, Dai Q. Calcium intake and ion transporter genetic polymorphisms interact in human colorectal neoplasia risk in a 2-phase study. J. Nutr [print-electronic]. 2014 Nov; 144(11): 1734-41. PMID: 25165391, PMCID: PMC4195417, PII: jn.114.196709, DOI: 10.3945/jn.114.196709, ISSN: 1541-6100.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25165391.
  • Luo Y, Wong CJ, Kaz AM, Dzieciatkowski S, Carter KT, Morris SM, Wang J, Willis JE, Makar KW, Ulrich CM, Lutterbaugh JD, Shrubsole MJ, Zheng W, Markowitz SD, Grady WM. Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology [print-electronic]. 2014 Aug; 147(2): 418-29.e8. PMID: 24793120, PMCID: PMC4107146, PII: S0016-5085(14)00595-2, DOI: 10.1053/j.gastro.2014.04.039, ISSN: 1528-0012.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24793120.
  • Cui Y, Deming-Halverson SL, Shrubsole MJ, Beeghly-Fadiel A, Cai H, Fair AM, Shu XO, Zheng W. Use of nonsteroidal anti-inflammatory drugs and reduced breast cancer risk among overweight women. Breast Cancer Res. Treat [print-electronic]. 2014 Jul; 146(2): 439-46. PMID: 24986698, PMCID: PMC4130355, DOI: 10.1007/s10549-014-3030-7, ISSN: 1573-7217.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24986698.
  • Kweon SS, Shu XO, Xiang Y, Yang G, Ji BT, Li H, Gao YT, Zheng W, Shrubsole MJ. One-carbon metabolism dietary factors and distal gastric cancer risk in chinese women. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2014 Jul; 23(7): 1374-82. PMID: 24789845, PMCID: PMC4082459, PII: 1055-9965.EPI-14-0038, DOI: 10.1158/1055-9965.EPI-14-0038, ISSN: 1538-7755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24789845.
  • Fu Z, Shrubsole MJ, Smalley WE, Ness RM, Zheng W. Associations between dietary fiber and colorectal polyp risk differ by polyp type and smoking status. J. Nutr [print-electronic]. 2014 May; 144(5): 592-8. PMID: 24572038, PMCID: PMC4084407, PII: jn.113.183319, DOI: 10.3945/jn.113.183319, ISSN: 1541-6100.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24572038.
  • Cui Y, Deming-Halverson SL, Beeghly-Fadiel A, Lipworth L, Shrubsole MJ, Fair AM, Shu XO, Zheng W. Interactions of hormone replacement therapy, body weight, and bilateral oophorectomy in breast cancer risk. Clin. Cancer Res [print-electronic]. 2014 Mar 3/1/2014; 20(5): 1169-78. PMID: 24423614, PMCID: PMC3972811, PII: 1078-0432.CCR-13-2094, DOI: 10.1158/1078-0432.CCR-13-2094, ISSN: 1078-0432.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24423614.
  • Cope EL, Shrubsole MJ, Cohen SS, Cai Q, Wu J, Ueland PM, Midttun Ø, Sonderman JS, Blot WJ, Signorello LB. Intraindividual variation in one-carbon metabolism plasma biomarkers. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2013 Oct; 22(10): 1894-9. PMID: 23950212, PMCID: PMC4104117, PII: 1055-9965.EPI-13-0420, DOI: 10.1158/1055-9965.EPI-13-0420, ISSN: 1538-7755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23950212.
  • Xuan D, Li G, Cai Q, Deming-Halverson S, Shrubsole MJ, Shu XO, Kelley MC, Zheng W, Long J. APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry. Carcinogenesis [print-electronic]. 2013 Oct; 34(10): 2240-3. PMID: 23715497, PMCID: PMC3786378, PII: bgt185, DOI: 10.1093/carcin/bgt185, ISSN: 1460-2180.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23715497.
  • Edwards TL, Shrubsole MJ, Cai Q, Li G, Dai Q, Rex DK, Ulbright TM, Fu Z, Delahanty RH, Murff HJ, Smalley W, Ness RM, Zheng W. Genome-wide association study identifies possible genetic risk factors for colorectal adenomas. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2013 Jul; 22(7): 1219-26. PMID: 23677573, PMCID: PMC3716448, PII: 1055-9965.EPI-12-1437, DOI: 10.1158/1055-9965.EPI-12-1437, ISSN: 1538-7755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23677573.
  • Fu Z, Shrubsole MJ, Li G, Smalley WE, Hein DW, Cai Q, Ness RM, Zheng W. Interaction of cigarette smoking and carcinogen-metabolizing polymorphisms in the risk of colorectal polyps. Carcinogenesis [print-electronic]. 2013 Apr; 34(4): 779-86. PMID: 23299405, PMCID: PMC3616674, PII: bgs410, DOI: 10.1093/carcin/bgs410, ISSN: 1460-2180.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23299405.
  • Dai Q, Shu XO, Deng X, Xiang YB, Li H, Yang G, Shrubsole MJ, Ji B, Cai H, Chow WH, Gao YT, Zheng W. Modifying effect of calcium/magnesium intake ratio and mortality: a population-based cohort study. BMJ Open [electronic-print]. 2013; 3(2): PMID: 23430595, PMCID: PMC3585973, PII: bmjopen-2012-002111, DOI: 10.1136/bmjopen-2012-002111, ISSN: 2044-6055.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23430595.
  • Deng X, Song Y, Manson JE, Signorello LB, Zhang SM, Shrubsole MJ, Ness RM, Seidner DL, Dai Q. Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III. BMC Med. 2013; 11: 187. PMID: 23981518, PMCID: PMC3765911, PII: 1741-7015-11-187, DOI: 10.1186/1741-7015-11-187, ISSN: 1741-7015.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23981518.
  • Long J, Zhang B, Signorello LB, Cai Q, Deming-Halverson S, Shrubsole MJ, Sanderson M, Dennis J, Michailidou K, Easton DF, Shu XO, Blot WJ, Zheng W. Evaluating genome-wide association study-identified breast cancer risk variants in African-American women. PLoS ONE [electronic-print]. 2013; 8(4): e58350. PMID: 23593120, PMCID: PMC3620157, PII: PONE-D-12-28396, DOI: 10.1371/journal.pone.0058350, ISSN: 1932-6203.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23593120.
  • Takata Y, Cai Q, Beeghly-Fadiel A, Li H, Shrubsole MJ, Ji BT, Yang G, Chow WH, Gao YT, Zheng W, Shu XO. Dietary B vitamin and methionine intakes and lung cancer risk among female never smokers in China. Cancer Causes Control [print-electronic]. 2012 Dec; 23(12): 1965-75. PMID: 23065072, PMCID: PMC3518409, DOI: 10.1007/s10552-012-0074-z, ISSN: 1573-7225.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23065072.
  • Zhang B, Shrubsole MJ, Li G, Cai Q, Edwards T, Smalley WE, Ness RM, Zheng W. Association of genetic variants for colorectal cancer differs by subtypes of polyps in the colorectum. Carcinogenesis [print-electronic]. 2012 Dec; 33(12): 2417-23. PMID: 23027627, PMCID: PMC3510743, PII: bgs308, DOI: 10.1093/carcin/bgs308, ISSN: 1460-2180.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23027627.
  • Fu Z, Shrubsole MJ, Smalley WE, Wu H, Chen Z, Shyr Y, Ness RM, Zheng W. Lifestyle factors and their combined impact on the risk of colorectal polyps. Am. J. Epidemiol [print-electronic]. 2012 Nov 11/1/2012; 176(9): 766-76. PMID: 23079606, PMCID: PMC3571253, PII: kws157, DOI: 10.1093/aje/kws157, ISSN: 1476-6256.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23079606.
  • Fu Z, Shrubsole MJ, Li G, Smalley WE, Hein DW, Chen Z, Shyr Y, Cai Q, Ness RM, Zheng W. Using gene-environment interaction analyses to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps. Am. J. Clin. Nutr [print-electronic]. 2012 Nov; 96(5): 1119-28. PMID: 23015320, PMCID: PMC3471199, PII: ajcn.112.040345, DOI: 10.3945/ajcn.112.040345, ISSN: 1938-3207.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23015320.
  • Edwards TL, Shrubsole MJ, Cai Q, Li G, Dai Q, Rex DK, Ulbright TM, Fu Z, Murff HJ, Smalley W, Ness R, Zheng W. A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenoma. Cancer Prev Res (Phila) [print-electronic]. 2012 Jun; 5(6): 855-63. PMID: 22551900, PMCID: PMC3789595, PII: 1940-6207.CAPR-11-0459, DOI: 10.1158/1940-6207.CAPR-11-0459, ISSN: 1940-6215.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22551900.
  • Luo J, Gao YT, Chow WH, Shu XO, Li H, Yang G, Cai Q, Li G, Rothman N, Cai H, Shrubsole MJ, Franke AA, Zheng W, Dai Q. Urinary polyphenols, glutathione S-transferases copy number variation, and breast cancer risk: results from the Shanghai women's health study. Mol. Carcinog [print-electronic]. 2012 May; 51(5): 379-88. PMID: 21557334, PMCID: PMC3257420, DOI: 10.1002/mc.20799, ISSN: 1098-2744.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21557334.
  • Murff HJ, Shrubsole MJ, Cai Q, Smalley WE, Dai Q, Milne GL, Ness RM, Zheng W. Dietary intake of PUFAs and colorectal polyp risk. Am. J. Clin. Nutr [print-electronic]. 2012 Mar; 95(3): 703-12. PMID: 22277551, PMCID: PMC3278245, PII: ajcn.111.024000, DOI: 10.3945/ajcn.111.024000, ISSN: 1938-3207.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22277551.
  • Shrubsole MJ, Cai Q, Wen W, Milne G, Smalley WE, Chen Z, Ness RM, Zheng W. Urinary prostaglandin E2 metabolite and risk for colorectal adenoma. Cancer Prev Res (Phila) [print-electronic]. 2012 Feb; 5(2): 336-42. PMID: 22166248, PMCID: PMC3273609, PII: 1940-6207.CAPR-11-0426, DOI: 10.1158/1940-6207.CAPR-11-0426, ISSN: 1940-6215.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22166248.
  • Xie M, Zhu X, Liu Z, Shrubsole M, Varma V, Mayer IA, Dai Q, Chen Q, You S. Membrane progesterone receptor alpha as a potential prognostic biomarker for breast cancer survival: a retrospective study. PLoS ONE [print-electronic]. 2012; 7(4): e35198. PMID: 22496908, PMCID: PMC3319632, PII: PONE-D-12-00201, DOI: 10.1371/journal.pone.0035198, ISSN: 1932-6203.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22496908.
  • Murff HJ, Shrubsole MJ, Chen Z, Smalley WE, Chen H, Shyr Y, Ness RM, Zheng W. Nonsteroidal anti-inflammatory drug use and risk of adenomatous and hyperplastic polyps. Cancer Prev Res (Phila) [print-electronic]. 2011 Nov; 4(11): 1799-807. PMID: 21764857, PMCID: PMC3203989, PII: 1940-6207.CAPR-11-0107, DOI: 10.1158/1940-6207.CAPR-11-0107, ISSN: 1940-6215.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21764857.
  • Fu Z, Deming SL, Fair AM, Shrubsole MJ, Wujcik DM, Shu XO, Kelley M, Zheng W. Well-done meat intake and meat-derived mutagen exposures in relation to breast cancer risk: the Nashville Breast Health Study. Breast Cancer Res. Treat [print-electronic]. 2011 Oct; 129(3): 919-28. PMID: 21537933, PMCID: PMC3775710, DOI: 10.1007/s10549-011-1538-7, ISSN: 1573-7217.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21537933.
  • Fu Z, Shrubsole MJ, Smalley WE, Wu H, Chen Z, Shyr Y, Ness RM, Zheng W. Association of meat intake and meat-derived mutagen exposure with the risk of colorectal polyps by histologic type. Cancer Prev Res (Phila) [print-electronic]. 2011 Oct; 4(10): 1686-97. PMID: 21803984, PMCID: PMC3188364, PII: 1940-6207.CAPR-11-0191, DOI: 10.1158/1940-6207.CAPR-11-0191, ISSN: 1940-6215.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21803984.
  • Dorjgochoo T, Gao YT, Chow WH, Shu XO, Yang G, Cai Q, Rothman N, Cai H, Li H, Deng X, Shrubsole MJ, Murff H, Milne G, Zheng W, Dai Q. Obesity, age, and oxidative stress in middle-aged and older women. Antioxid. Redox Signal [print-electronic]. 2011 Jun 6/15/2011; 14(12): 2453-60. PMID: 21043829, PMCID: PMC3096497, DOI: 10.1089/ars.2010.3337, ISSN: 1557-7716.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21043829.
  • Shrubsole MJ, Shu XO, Li HL, Cai H, Yang G, Gao YT, Gao J, Zheng W. Dietary B vitamin and methionine intakes and breast cancer risk among Chinese women. Am. J. Epidemiol [print-electronic]. 2011 May 5/15/2011; 173(10): 1171-82. PMID: 21447479, PMCID: PMC3121320, PII: kwq491, DOI: 10.1093/aje/kwq491, ISSN: 1476-6256.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21447479.
  • You L, Zhu X, Shrubsole MJ, Fan H, Chen J, Dong J, Hao CM, Dai Q. Renal function, bisphenol A, and alkylphenols: results from the National Health and Nutrition Examination Survey (NHANES 2003-2006). Environ. Health Perspect [print-electronic]. 2011 Apr; 119(4): 527-33. PMID: 21147601, PMCID: PMC3080936, DOI: 10.1289/ehp.1002572, ISSN: 1552-9924.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21147601.
  • Cai Q, Wen W, Qu S, Li G, Egan KM, Chen K, Deming SL, Shen H, Shen CY, Gammon MD, Blot WJ, Matsuo K, Haiman CA, Khoo US, Iwasaki M, Santella RM, Zhang L, Fair AM, Hu Z, Wu PE, Signorello LB, Titus-Ernstoff L, Tajima K, Henderson BE, Chan KY, Kasuga Y, Newcomb PA, Zheng H, Cui Y, Wang F, Shieh YL, Iwata H, Le Marchand L, Chan SY, Shrubsole MJ, Trentham-Dietz A, Tsugane S, Garcia-Closas M, Long J, Li C, Shi J, Huang B, Xiang YB, Gao YT, Lu W, Shu XO, Zheng W. Replication and functional genomic analyses of the breast cancer susceptibility locus at 6q25.1 generalize its importance in women of chinese, Japanese, and European ancestry. Cancer Res [print-electronic]. 2011 Feb 2/15/2011; 71(4): 1344-55. PMID: 21303983, PMCID: PMC3083305, PII: 0008-5472.CAN-10-2733, DOI: 10.1158/0008-5472.CAN-10-2733, ISSN: 1538-7445.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21303983.
  • Long J, Cai Q, Shu XO, Qu S, Li C, Zheng Y, Gu K, Wang W, Xiang YB, Cheng J, Chen K, Zhang L, Zheng H, Shen CY, Huang CS, Hou MF, Shen H, Hu Z, Wang F, Deming SL, Kelley MC, Shrubsole MJ, Khoo US, Chan KY, Chan SY, Haiman CA, Henderson BE, Le Marchand L, Iwasaki M, Kasuga Y, Tsugane S, Matsuo K, Tajima K, Iwata H, Huang B, Shi J, Li G, Wen W, Gao YT, Lu W, Zheng W. Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium. PLoS Genet. 2010 Jun; 6(6): e1001002. PMID: 20585626, PMCID: PMC2891809, DOI: 10.1371/journal.pgen.1001002, ISSN: 1553-7404.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20585626.
  • Luo J, Gao YT, Chow WH, Shu XO, Li H, Yang G, Cai Q, Rothman N, Cai H, Shrubsole MJ, Franke AA, Zheng W, Dai Q. Urinary polyphenols and breast cancer risk: results from the Shanghai Women's Health Study. Breast Cancer Res. Treat [print-electronic]. 2010 Apr; 120(3): 693-702. PMID: 19653095, PMCID: PMC2842475, DOI: 10.1007/s10549-009-0487-x, ISSN: 1573-7217.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19653095.
  • Dai Q, Shu XO, Li H, Yang G, Shrubsole MJ, Cai H, Ji B, Wen W, Franke A, Gao YT, Zheng W. Is green tea drinking associated with a later onset of breast cancer?. Ann Epidemiol. 2010 Jan; 20(1): 74-81. PMID: 20006278, PMCID: PMC2848451, PII: S1047-2797(09)00317-2, DOI: 10.1016/j.annepidem.2009.09.005, ISSN: 1873-2585.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20006278.
  • Zhang MZ, Xu J, Yao B, Yin H, Cai Q, Shrubsole MJ, Chen X, Kon V, Zheng W, Pozzi A, Harris RC. Inhibition of 11beta-hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans. J. Clin. Invest [print-electronic]. 2009 Apr; 119(4): 876-85. PMID: 19307727, PMCID: PMC2662561, PII: 37398, DOI: 10.1172/JCI37398, ISSN: 1558-8238.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19307727.
  • Shrubsole MJ, Yang G, Gao YT, Chow WH, Shu XO, Cai Q, Rothman N, Gao J, Wagner C, Zheng W. Dietary B vitamin and methionine intakes and plasma folate are not associated with colorectal cancer risk in Chinese women. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2009 Mar; 18(3): 1003-6. PMID: 19240230, PMCID: PMC2677023, PII: 1055-9965.EPI-08-1200, DOI: 10.1158/1055-9965.EPI-08-1200, ISSN: 1055-9965.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19240230.
  • Shrubsole MJ, Lu W, Chen Z, Shu XO, Zheng Y, Dai Q, Cai Q, Gu K, Ruan ZX, Gao YT, Zheng W. Drinking green tea modestly reduces breast cancer risk. J. Nutr [print-electronic]. 2009 Feb; 139(2): 310-6. PMID: 19074205, PMCID: PMC2646205, PII: jn.108.098699, DOI: 10.3945/jn.108.098699, ISSN: 1541-6100.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19074205.
  • Wu H, Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Smalley WE, Chen H, Li M, Shyr Y, Zheng W. Fruit and vegetable intakes are associated with lower risk of colorectal adenomas. J. Nutr [print-electronic]. 2009 Feb; 139(2): 340-4. PMID: 19091801, PMCID: PMC2646202, PII: jn.108.098889, DOI: 10.3945/jn.108.098889, ISSN: 1541-6100.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19091801.
  • Shrubsole, MJ, Yang, G, Gao, YT, Chow, WH, Shu, XO, Gao, J, Cai, Q, Rothman, N, Wagner, C, Zheng, W. Dietary B vitamin and methionine intakes and plasma folate are not associated with colorectal cancer risk in Chinese women. Cancer Epidemiol Biomarkers Prev. 2009; 18((3)): 1003-6.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19240230?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum.
  • Zhang, MZ, Xu, J, Yao, B, Yin, H, Cai, Q, Shrubsole, MJ, Chen, X, Kon, V, Zheng, W. Inhibition of 11β hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans. J Clin Invest. 2009; 119((4)): 876-85.
    Available from: http://www.ncbi.nlm.nih.gov/sites/entrez.
  • Dorjgochoo T, Shrubsole MJ, Shu XO, Lu W, Ruan Z, Zheng Y, Cai H, Dai Q, Gu K, Gao YT, Zheng W. Vitamin supplement use and risk for breast cancer: the Shanghai Breast Cancer Study. Breast Cancer Res. Treat [print-electronic]. 2008 Sep; 111(2): 269-78. PMID: 17917808, PMCID: PMC2615487, DOI: 10.1007/s10549-007-9772-8, ISSN: 0167-6806.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17917808.
  • Shrubsole MJ, Wu H, Ness RM, Shyr Y, Smalley WE, Zheng W. Alcohol drinking, cigarette smoking, and risk of colorectal adenomatous and hyperplastic polyps. Am. J. Epidemiol [print-electronic]. 2008 May 5/1/2008; 167(9): 1050-8. PMID: 18304959, PII: kwm400, DOI: 10.1093/aje/kwm400, ISSN: 1476-6256.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18304959.
  • Shin A, Shrubsole MJ, Rice JM, Cai Q, Doll MA, Long J, Smalley WE, Shyr Y, Sinha R, Ness RM, Hein DW, Zheng W. Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk. Cancer Epidemiol. Biomarkers Prev. 2008 Feb; 17(2): 320-9. PMID: 18268115, PMCID: PMC2572782, PII: 17/2/320, DOI: 10.1158/1055-9965.EPI-07-0615, ISSN: 1055-9965.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18268115.
  • Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Cai Q, Smalley WE, Li M, Shyr Y, Zheng W. The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. Am. J. Clin. Nutr. 2007 Sep; 86(3): 743-51. PMID: 17823441, PMCID: PMC2082111, PII: 86/3/743, ISSN: 0002-9165.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17823441.
  • Shin A, Shrubsole MJ, Ness RM, Wu H, Sinha R, Smalley WE, Shyr Y, Zheng W. Meat and meat-mutagen intake, doneness preference and the risk of colorectal polyps: the Tennessee Colorectal Polyp Study. Int. J. Cancer. 2007 Jul 7/1/2007; 121(1): 136-42. PMID: 17354224, DOI: 10.1002/ijc.22664, ISSN: 0020-7136.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17354224.
  • Murff HJ, Peterson NB, Greevy RA, Shrubsole MJ, Zheng W. Early initiation of colorectal cancer screening in individuals with affected first-degree relatives. J Gen Intern Med. 2007 Jan; 22(1): 121-6. PMID: 17351851, PMCID: PMC1824778, DOI: 10.1007/s11606-007-0115-6, ISSN: 1525-1497.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17351851.
  • Murff HJ, Shrubsole MJ, Smalley WE, Wu H, Shyr Y, Ness RM, Zheng W. The interaction of age and hormone replacement therapy on colon adenoma risk. Cancer Detect. Prev [print-electronic]. 2007; 31(2): 161-5. PMID: 17433566, PMCID: PMC1949417, PII: S0361-090X(07)00034-7, DOI: 10.1016/j.cdp.2007.03.002, ISSN: 0361-090X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17433566.
  • Xu, WH, Shrubsole, MJ, Xiang, YB, Cai, Q, Zhao, GM, Ruan, ZX, Cheng, JR, Zheng, W, Shu, XO. Dietary folate intake, MTHFR genetic polymorphisms, and the risk of endometrial cancer among Chinese women. Cancer Epidemiology, Biomarkers, & Prevention. 2007; 16((2)): 281-7.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17301261?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum.
  • Johnson JC, Schmidt CR, Shrubsole MJ, Billheimer DD, Joshi PR, Morrow JD, Heslin MJ, Washington MK, Ness RM, Zheng W, Schwartz DA, Coffey RJ, Beauchamp RD, Merchant NB. Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin. Gastroenterol. Hepatol [print-electronic]. 2006 Nov; 4(11): 1358-65. PMID: 16996805, PII: S1542-3565(06)00772-5, DOI: 10.1016/j.cgh.2006.07.015, ISSN: 1542-3565.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16996805.
  • Su Y, Shrubsole MJ, Ness RM, Cai Q, Kataoka N, Washington K, Zheng W. Immunohistochemical expressions of Ki-67, cyclin D1, beta-catenin, cyclooxygenase-2, and epidermal growth factor receptor in human colorectal adenoma: a validation study of tissue microarrays. Cancer Epidemiol. Biomarkers Prev. 2006 Sep; 15(9): 1719-26. PMID: 16985035, PII: 15/9/1719, DOI: 10.1158/1055-9965.EPI-05-0946, ISSN: 1055-9965.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16985035.
  • Ye C, Shrubsole MJ, Cai Q, Ness R, Grady WM, Smalley W, Cai H, Washington K, Zheng W. Promoter methylation status of the MGMT, hMLH1, and CDKN2A/p16 genes in non-neoplastic mucosa of patients with and without colorectal adenomas. Oncol. Rep. 2006 Aug; 16(2): 429-35. PMID: 16820927, ISSN: 1021-335X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16820927.
  • Shrubsole MJ, Gao YT, Cai Q, Shu XO, Dai Q, Jin F, Zheng W. MTR and MTRR polymorphisms, dietary intake, and breast cancer risk. Cancer Epidemiol. Biomarkers Prev. 2006 Mar; 15(3): 586-8. PMID: 16537721, PII: 15/3/586, DOI: 10.1158/1055-9965.EPI-05-0576, ISSN: 1055-9965.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16537721.
  • Shrubsole MJ, Shu XO, Ruan ZX, Cai Q, Cai H, Niu Q, Gao YT, Zheng W. MTHFR genotypes and breast cancer survival after surgery and chemotherapy: a report from the Shanghai Breast Cancer Study. Breast Cancer Res. Treat. 2005 May; 91(1): 73-9. PMID: 15868433, DOI: 10.1007/s10549-004-7265-6, ISSN: 0167-6806.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15868433.
  • Shrubsole MJ, Gao YT, Dai Q, Shu XO, Ruan ZX, Jin F, Zheng W. Passive smoking and breast cancer risk among non-smoking Chinese women. Int. J. Cancer. 2004 Jul 7/1/2004; 110(4): 605-9. PMID: 15122595, DOI: 10.1002/ijc.20168, ISSN: 0020-7136.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15122595.
  • Shrubsole MJ, Gao YT, Cai Q, Shu XO, Dai Q, Hébert JR, Jin F, Zheng W. MTHFR polymorphisms, dietary folate intake, and breast cancer risk: results from the Shanghai Breast Cancer Study. Cancer Epidemiol. Biomarkers Prev. 2004 Feb; 13(2): 190-6. PMID: 14973091, ISSN: 1055-9965.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14973091.
  • Yang G, Lu G, Jin F, Dai Q, Best R, Shu XO, Chen JR, Pan XY, Shrubsole M, Zheng W. Population-based, case-control study of blood C-peptide level and breast cancer risk. Cancer Epidemiol. Biomarkers Prev. 2001 Nov; 10(11): 1207-11. PMID: 11700270, ISSN: 1055-9965.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11700270.
  • Shrubsole MJ, Jin F, Dai Q, Shu XO, Potter JD, Hebert JR, Gao YT, Zheng W. Dietary folate intake and breast cancer risk: results from the Shanghai Breast Cancer Study. Cancer Res. 2001 Oct 10/1/2001; 61(19): 7136-41. PMID: 11585746, ISSN: 0008-5472.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11585746.