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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center

 
Michael R.   Savona

Michael R. Savona, M.D.

Associate Professor of Medicine
Director, Hematology Early Therapeutics Program

  • Appointments
    877-936-8422
    Physicians: 1-877-936-8422
  • Clinical Trials Information
  • Other Telephone Numbers
    Division of Hematology/Oncology
    (615) 322-4967

    Henry-Joyce Cancer Clinic
    (615) 936-8422 or 1 (877) 936-8422

  • Faxes
    Division of Hematology/Oncology Fax
    (615) 343-7602
    Henry-Joyce Cancer Clinic Fax
    (615) 343-8668
  • Addresses
    Division of Hematology/Oncology
    2220 Pierce Ave, 777 PRB
    Nashville, TN 37232-6307
    Website

    Henry-Joyce Cancer Clinic
    1301 Medical Center Drive, Suite 1710
    Nashville, Tennessee 37232-7415
    Website

Education
  • M.D., Wake Forest University School of Medicine, Winston-Salem, North Carolina (2002)
  • B.A., Davidson College, Davidson, North Carolina (1994)
   
Publications
  • Savona MR, Malcovati L, Komrokji R, Tiu RV, Mughal TI, Orazi A, Kiladjian JJ, Padron E, Solary E, Tibes R, Itzykson R, Cazzola M, Mesa R, Maciejewski J, Fenaux P, Garcia-Manero G, Gerds A, Sanz G, Niemeyer CM, Cervantes F, Germing U, Cross NC, List AF, . An international consortium proposal of uniform response criteria for myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in adults. Blood [print-electronic]. 2015 Mar 3/19/2015; 125(12): 1857-65. PMID: 25624319, PII: blood-2014-10-607341, DOI: 10.1182/blood-2014-10-607341, ISSN: 1528-0020.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25624319.
  • Savona MR. Are we altering the natural history of primary myelofibrosis?. Leuk. Res [print-electronic]. 2014 Sep; 38(9): 1004-12. PMID: 24931396, PII: S0145-2126(14)00123-4, DOI: 10.1016/j.leukres.2014.04.012, ISSN: 1873-5835.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24931396.
  • Laille E, Savona MR, Scott BL, Boyd TE, Dong Q, Skikne B. Pharmacokinetics of different formulations of oral azacitidine (CC-486) and the effect of food and modified gastric pH on pharmacokinetics in subjects with hematologic malignancies. J Clin Pharmacol [print-electronic]. 2014 Jun; 54(6): 630-9. PMID: 24374798, DOI: 10.1002/jcph.251, ISSN: 1552-4604.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24374798.
  • Savona MR. Molecular monitoring and minimal residual disease in the management of chronic myelogenous leukemia. J Community Support Oncol. 2014 May; 12(5): 171-8. PMID: 24971427, ISSN: 2330-7749.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24971427.
  • Savona MR, Saglio G. Identifying the time to change BCR-ABL inhibitor therapy in patients with chronic myeloid leukemia. Acta Haematol [print-electronic]. 2013; 130(4): 268-78. PMID: 23949495, PII: 000353163, DOI: 10.1159/000353163, ISSN: 1421-9662.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23949495.
  • Carter CC, McNamara LA, Onafuwa-Nuga A, Shackleton M, Riddell J, Bixby D, Savona MR, Morrison SJ, Collins KL. HIV-1 utilizes the CXCR4 chemokine receptor to infect multipotent hematopoietic stem and progenitor cells. Cell Host Microbe. 2011 Mar 3/17/2011; 9(3): 223-34. PMID: 21402361, PMCID: PMC3102232, PII: S1931-3128(11)00039-4, DOI: 10.1016/j.chom.2011.02.005, ISSN: 1934-6069.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21402361.
  • Brown AW, Savona MR. CD9 phones home with a TEM of its own. Blood. 2011 Feb 2/10/2011; 117(6): 1775-6. PMID: 21310932, PII: 117/6/1775, DOI: 10.1182/blood-2010-11-320077, ISSN: 1528-0020.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21310932.
  • Larochelle A, Savona M, Wiggins M, Anderson S, Ichwan B, Keyvanfar K, Morrison SJ, Dunbar CE. Human and rhesus macaque hematopoietic stem cells cannot be purified based only on SLAM family markers. Blood [print-electronic]. 2011 Feb 2/3/2011; 117(5): 1550-4. PMID: 21163926, PMCID: PMC3318774, PII: blood-2009-03-212803, DOI: 10.1182/blood-2009-03-212803, ISSN: 1528-0020.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21163926.
  • Carter CC, Onafuwa-Nuga A, McNamara LA, Riddell J, Bixby D, Savona MR, Collins KL. HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs. Nat. Med [print-electronic]. 2010 Apr; 16(4): 446-51. PMID: 20208541, PMCID: PMC2892382, PII: nm.2109, DOI: 10.1038/nm.2109, ISSN: 1546-170X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20208541.
  • Cooper S, Giles FJ, Savona MR. Overcoming resistance in chronic myelogenous leukemia. Leuk. Lymphoma. 2009 Nov; 50(11): 1785-93. PMID: 19883308, PII: 10.3109/10428190903267559, DOI: 10.3109/10428190903267559, ISSN: 1029-2403.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19883308.
  • McGregor BA, Brown AW, Osswald MB, Savona MR. The use of higher dose clofarabine in adults with relapsed acute lymphoblastic leukemia. Am. J. Hematol. 2009 Apr; 84(4): 228-30. PMID: 19260120, DOI: 10.1002/ajh.21365, ISSN: 1096-8652.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19260120.
  • Savona M, Talpaz M. Getting to the stem of chronic myeloid leukaemia. Nat. Rev. Cancer. 2008 May; 8(5): 341-50. PMID: 18385684, PII: nrc2368, DOI: 10.1038/nrc2368, ISSN: 1474-1768.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18385684.
  • Savona MR, Silver SM. Erythropoietin-stimulating agents in oncology. Cancer J. 2008 Mar; 14(2): 75-84. PMID: 18391611, PII: 00130404-200803000-00002, DOI: 10.1097/PPO.0b013e31816a5f51, ISSN: 1528-9117.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18391611.
  • Savona MR, Cruz WP, Thornton JA, Danaher PJ. Comparison of a semipermeable dressing bonded to an absorbent pad and a semipermeable dressing over a separate gauze pad for containment of vaccinia virus at the vaccination site. Infect Control Hosp Epidemiol [print-electronic]. 2007 Dec; 28(12): 1339-43. PMID: 17952843, PII: ICHE2007259, DOI: 10.1086/523277, ISSN: 0899-823X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17952843.
  • Savona M, Talpaz M. Chronic myeloid leukemia: changing the treatment paradigms. Oncology (Williston Park, N.Y.). 2006 Jun; 20(7): 707-11; discussion 712. PMID: 16841795, PII: 164571, ISSN: 0890-9091.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16841795.
  • Savona MR, Dela Cruz WP, Jones MS, Thornton JA, Xia D, Hadfield TL, Danaher PJ. Detection of vaccinia DNA in the blood following smallpox vaccination [letter]. JAMA. 2006 Apr 4/26/2006; 295(16): 1898-900. PMID: 16639047, PII: 295/16/1898, DOI: 10.1001/jama.295.16.1898, ISSN: 1538-3598.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16639047.
  • Vaught C, Young DR, Bell SJ, Maynard C, Gentry M, Jacubowitz S, Leibrandt PN, Munsey D, Savona MR, Wall TC, Wagner GS. The failure of years of experience with electrocardiographic transmission from paramedics to the hospital emergency department to reduce the delay from door to primary coronary intervention below the 90-minute threshold during acute myocardial infarction. J Electrocardiol. 2006 Apr; 39(2): 136-41. PMID: 16580408, PII: S0022-0736(05)00373-0, DOI: 10.1016/j.jelectrocard.2005.12.002, ISSN: 0022-0736.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16580408.