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Raymond C. Harris, Jr., M.D.

Ann and Roscoe R. Robinson Professor of Medicine (Nephrology)
Chief, Divsion of Nephrology and Hypertension
Researcher

Contact Information:

Vanderbilt University Medical Center
S-3223 Medical Center North
Nashville, TN 37232-2372
615-343-0030

Publications
  • Wang F, Kopylov D, Zu Z, Takahashi K, Wang S, Quarles CC, Gore JC, Harris RC, Takahashi T. Mapping murine diabetic kidney disease using chemical exchange saturation transfer MRI. Magn Reson Med [print-electronic]. 2016 Nov; 76(5): 1531-41. PMID: 26608660, PMCID: PMC4882276, DOI: 10.1002/mrm.26045, ISSN: 0740-3194.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26608660.
  • Zhang MZ, Wang X, Wang Y, Niu A, Wang S, Zou C, Harris RC. IL-4/IL-13-mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury. Kidney Int [print-electronic]. 2016 Oct 10/10/2016; PMID: 27745702, PII: S0085-2538(16)30467-7, DOI: 10.1016/j.kint.2016.08.020, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/27745702.
  • Zeng F, Kloepfer LA, Finney C, Diedrich A, Harris RC. Specific endothelial heparin-binding EGF-like growth factor deletion ameliorates renal injury induced by chronic angiotensin II infusion. Am. J. Physiol. Renal Physiol [print-electronic]. 2016 Oct 10/1/2016; 311(4): F695-F707. PMID: 27226110, PII: ajprenal.00377.2015, DOI: 10.1152/ajprenal.00377.2015, ISSN: 1522-1466.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/27226110.
  • Skrypnyk NI, Voziyan P, Yang H, de Caestecker CR, Theberge MC, Drouin M, Hudson B, Harris RC, de Caestecker MP. Pyridoxamine reduces postinjury fibrosis and improves functional recovery after acute kidney injury. Am. J. Physiol. Renal Physiol [print-electronic]. 2016 Aug 8/1/2016; 311(2): F268-77. PMID: 27194713, PMCID: PMC5008672, PII: ajprenal.00056.2016, DOI: 10.1152/ajprenal.00056.2016, ISSN: 1522-1466.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/27194713.
  • Harris RC, Cheng H. Telomerase, Autophagy and Acute Kidney Injury. Nephron [print-electronic]. 2016 Jul 7/5/2016; PMID: 27376761, PII: 000446665, DOI: 10.1159/000446665, ISSN: 2235-3186.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/27376761.
  • Chen J, Harris RC. Interaction of the EGF Receptor and the Hippo Pathway in the Diabetic Kidney. J. Am. Soc. Nephrol [print-electronic]. 2016 Jun; 27(6): 1689-700. PMID: 26453611, PMCID: PMC4884112, PII: ASN.2015040415, DOI: 10.1681/ASN.2015040415, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26453611.
  • Harris RC, Ibrahim T, Nath KA. Celebrating the ASN at 50 [editorial]. J. Am. Soc. Nephrol [print-electronic]. 2016 Jun; 27(6): 1575-6. PMID: 27142707, PMCID: PMC4884129, PII: ASN.2016040445, DOI: 10.1681/ASN.2016040445, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/27142707.
  • Nlandu Khodo S, Neelisetty S, Woodbury L, Green E, Harris RC, Zent R, Gewin L. Deleting the TGF-ß receptor in proximal tubules impairs HGF signaling. Am. J. Physiol. Renal Physiol [print-electronic]. 2016 Mar 3/15/2016; 310(6): F499-510. PMID: 26739889, PMCID: PMC4796273, PII: ajprenal.00446.2015, DOI: 10.1152/ajprenal.00446.2015, ISSN: 1522-1466.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26739889.
  • Perrien DS, Saleh MA, Takahashi K, Madhur MS, Harrison DG, Harris RC, Takahashi T. Novel methods for microCT-based analyses of vasculature in the renal cortex reveal a loss of perfusable arterioles and glomeruli in eNOS-/- mice. BMC Nephrol. 2016 Mar 3/2/2016; 17: 24. PMID: 26936597, PMCID: PMC4776352, PII: 10.1186/s12882-016-0235-5, DOI: 10.1186/s12882-016-0235-5, ISSN: 1471-2369.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26936597.
  • Choma DP, Vanacore R, Naylor H, Zimmerman IA, Pavlichenko A, Pavlichenko A, Foye L, Carbone DP, Harris RC, Dikov MM, Tchekneva EE. Aquaporin 11 variant associates with kidney disease in type 2 diabetic patients. Am. J. Physiol. Renal Physiol [print-electronic]. 2016 Mar 3/1/2016; 310(5): F416-25. PMID: 26719361, PMCID: PMC4773830, PII: ajprenal.00295.2015, DOI: 10.1152/ajprenal.00295.2015, ISSN: 1522-1466.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26719361.
  • Forrester SJ, Kawai T, O'Brien S, Thomas W, Harris RC, Eguchi S. Epidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular System. Annu. Rev. Pharmacol. Toxicol [print-electronic]. 2016; 56: 627-53. PMID: 26566153, DOI: 10.1146/annurev-pharmtox-070115-095427, ISSN: 1545-4304.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26566153.
  • Wang Y, Chang J, Yao B, Niu A, Kelly E, Breeggemann MC, Abboud Werner SL, Harris RC, Zhang MZ. Proximal tubule-derived colony stimulating factor-1 mediates polarization of renal macrophages and dendritic cells, and recovery in acute kidney injury. Kidney Int [print-electronic]. 2015 Dec; 88(6): 1274-82. PMID: 26422503, PMCID: PMC4675680, PII: S0085-2538(15)61063-8, DOI: 10.1038/ki.2015.295, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26422503.
  • Ebert T, Kralisch S, Klöting N, Hoffmann A, Blüher M, Zhang MZ, Harris RC, Stumvoll M, Fasshauer M. Circulating progranulin but not renal progranulin expression is increased in renal dysfunction [letter]. Kidney Int. 2015 Nov; 88(5): 1197-8. PMID: 26579686, PII: S0085-2538(15)61015-8, DOI: 10.1038/ki.2015.266, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26579686.
  • Hsu CY, Parker MG, Ross MJ, Schmidt RJ, Harris RC, . Improving the Nephrology Match: the Path Forward. J. Am. Soc. Nephrol [print-electronic]. 2015 Nov; 26(11): 2634-9. PMID: 26341128, PMCID: PMC4625687, PII: ASN.2015040420, DOI: 10.1681/ASN.2015040420, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26341128.
  • Chang J, Vacher J, Yao B, Fan X, Zhang B, Harris RC, Zhang MZ. Prostaglandin E receptor 4 (EP4) promotes colonic tumorigenesis. Oncotarget. 2015 Oct 10/20/2015; 6(32): 33500-11. PMID: 26378024, PMCID: PMC4741781, PII: 5589, DOI: 10.18632/oncotarget.5589, ISSN: 1949-2553.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26378024.
  • Neelisetty S, Alford C, Reynolds K, Woodbury L, Nlandu-Khodo S, Yang H, Fogo AB, Hao CM, Harris RC, Zent R, Gewin L. Renal fibrosis is not reduced by blocking transforming growth factor-ß signaling in matrix-producing interstitial cells. Kidney Int [print-electronic]. 2015 Sep; 88(3): 503-14. PMID: 25760325, PMCID: PMC4556568, PII: ki201551, DOI: 10.1038/ki.2015.51, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25760325.
  • Singh SP, Tao S, Fields TA, Webb S, Harris RC, Rao R. Glycogen synthase kinase-3 inhibition attenuates fibroblast activation and development of fibrosis following renal ischemia-reperfusion in mice. Dis Model Mech [print-electronic]. 2015 Aug 8/1/2015; 8(8): 931-40. PMID: 26092126, PMCID: PMC4527294, PII: dmm.020511, DOI: 10.1242/dmm.020511, ISSN: 1754-8411.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26092126.
  • Cheng H, Fan X, Lawson WE, Paueksakon P, Harris RC. Telomerase deficiency delays renal recovery in mice after ischemia-reperfusion injury by impairing autophagy. Kidney Int [print-electronic]. 2015 Jul; 88(1): 85-94. PMID: 25760322, PMCID: PMC4490111, PII: ki201569, DOI: 10.1038/ki.2015.69, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25760322.
  • Fan Y, Li X, Xiao W, Fu J, Harris RC, Lindenmeyer M, Cohen CD, Guillot N, Baron MH, Wang N, Lee K, He JC, Schlondorff D, Chuang PY. BAMBI elimination enhances alternative TGF-ß signaling and glomerular dysfunction in diabetic mice. Diabetes [print-electronic]. 2015 Jun; 64(6): 2220-33. PMID: 25576053, PMCID: PMC4439561, PII: db14-1397, DOI: 10.2337/db14-1397, ISSN: 1939-327X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25576053.
  • Fan Y, Li X, Xiao W, Fu J, Harris RC, Lindenmeyer M, Cohen CD, Guillot N, Baron MH, Wang N, Lee K, He JC, Schlondorff D, Chuang PY. BAMBI elimination enhances alternative TGF-ß signaling and glomerular dysfunction in diabetic mice. Diabetes [print-electronic]. 2015 Jun; 64(6): 2220-33. PMID: 25576053, PMCID: PMC4439561, PII: db14-1397, DOI: 10.2337/db14-1397, ISSN: 1939-327X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25576053.
  • Chen J, Chen JK, Harris RC. EGF receptor deletion in podocytes attenuates diabetic nephropathy. J. Am. Soc. Nephrol [print-electronic]. 2015 May; 26(5): 1115-25. PMID: 25185988, PMCID: PMC4413759, PII: ASN.2014020192, DOI: 10.1681/ASN.2014020192, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25185988.
  • Wang H, Chen X, Su Y, Paueksakon P, Hu W, Zhang MZ, Harris RC, Blackwell TS, Zent R, Pozzi A. P47(phox) contributes to albuminuria and kidney fibrosis in mice. Kidney Int [print-electronic]. 2015 May; 87(5): 948-62. PMID: 25565313, PMCID: PMC4425591, PII: S0085-2538(15)30097-1, DOI: 10.1038/ki.2014.386, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25565313.
  • Wang H, Chen X, Su Y, Paueksakon P, Hu W, Zhang MZ, Harris RC, Blackwell TS, Zent R, Pozzi A. P47(phox) contributes to albuminuria and kidney fibrosis in mice. Kidney Int [print-electronic]. 2015 May; 87(5): 948-62. PMID: 25565313, PMCID: PMC4425591, PII: ki2014386, DOI: 10.1038/ki.2014.386, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25565313.
  • Zhang MZ, Harris RC. Antihypertensive mechanisms of intra-renal dopamine. Curr. Opin. Nephrol. Hypertens. 2015 Mar; 24(2): 117-22. PMID: 25594544, PMCID: PMC4651846, DOI: 10.1097/MNH.0000000000000104, ISSN: 1473-6543.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25594544.
  • Ma SK, Wang Y, Chen J, Zhang MZ, Harris RC, Chen JK. Overexpression of G-protein-coupled receptor 40 enhances the mitogenic response to epoxyeicosatrienoic acids. PLoS ONE. 2015; 10(2): e0113130. PMID: 25679385, PMCID: PMC4332471, PII: PONE-D-14-35770, DOI: 10.1371/journal.pone.0113130, ISSN: 1932-6203.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25679385.
  • Reisin E, Harris RC, Rahman M. Commentary on the 2014 BP guidelines from the panel appointed to the Eighth Joint National Committee (JNC 8). J. Am. Soc. Nephrol [print-electronic]. 2014 Nov; 25(11): 2419-24. PMID: 25114277, PMCID: PMC4214539, PII: ASN.2014040371, DOI: 10.1681/ASN.2014040371, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25114277.
  • Reisin E, Harris RC, Rahman M. Commentary on the 2014 BP guidelines from the panel appointed to the Eighth Joint National Committee (JNC 8). J. Am. Soc. Nephrol [print-electronic]. 2014 Nov; 25(11): 2419-24. PMID: 25114277, PMCID: PMC4214539, PII: ASN.2014040371, DOI: 10.1681/ASN.2014040371, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25114277.
  • Wang F, Jiang R, Takahashi K, Gore J, Harris RC, Takahashi T, Quarles CC. Longitudinal assessment of mouse renal injury using high-resolution anatomic and magnetization transfer MR imaging. Magn Reson Imaging [print-electronic]. 2014 Nov; 32(9): 1125-32. PMID: 25093632, PMCID: PMC4171209, PII: S0730-725X(14)00215-X, DOI: 10.1016/j.mri.2014.07.012, ISSN: 1873-5894.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25093632.
  • Wang F, Jiang R, Takahashi K, Gore J, Harris RC, Takahashi T, Quarles CC. Longitudinal assessment of mouse renal injury using high-resolution anatomic and magnetization transfer MR imaging. Magn Reson Imaging [print-electronic]. 2014 Nov; 32(9): 1125-32. PMID: 25093632, PMCID: PMC4171209, PII: S0730-725X(14)00215-X, DOI: 10.1016/j.mri.2014.07.012, ISSN: 1873-5894.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25093632.
  • Zeng F, Miyazawa T, Kloepfer LA, Harris RC. Deletion of ErbB4 accelerates polycystic kidney disease progression in cpk mice. Kidney Int [print-electronic]. 2014 Sep; 86(3): 538-47. PMID: 24670412, PMCID: PMC4149866, PII: S0085-2538(15)30329-X, DOI: 10.1038/ki.2014.84, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24670412.
  • Zeng F, Miyazawa T, Kloepfer LA, Harris RC. Deletion of ErbB4 accelerates polycystic kidney disease progression in cpk mice. Kidney Int [print-electronic]. 2014 Sep; 86(3): 538-47. PMID: 24670412, PMCID: PMC4149866, PII: ki201484, DOI: 10.1038/ki.2014.84, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24670412.
  • Grove KJ, Voziyan PA, Spraggins JM, Wang S, Paueksakon P, Harris RC, Hudson BG, Caprioli RM. Diabetic nephropathy induces alterations in the glomerular and tubule lipid profiles. J. Lipid Res [print-electronic]. 2014 Jul; 55(7): 1375-85. PMID: 24864273, PMCID: PMC4076088, PII: jlr.M049189, DOI: 10.1194/jlr.M049189, ISSN: 1539-7262.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24864273.
  • Zhang MZ, Wang Y, Paueksakon P, Harris RC. Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagy. Diabetes [print-electronic]. 2014 Jun; 63(6): 2063-72. PMID: 24705402, PMCID: PMC4030104, PII: db13-1279, DOI: 10.2337/db13-1279, ISSN: 1939-327X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24705402.
  • Wang F, Jiang RT, Tantawy MN, Borza DB, Takahashi K, Gore JC, Harris RC, Takahashi T, Quarles CC. Repeatability and sensitivity of high resolution blood volume mapping in mouse kidney disease. J Magn Reson Imaging [print-electronic]. 2014 Apr; 39(4): 866-71. PMID: 24006202, PMCID: PMC3858530, DOI: 10.1002/jmri.24242, ISSN: 1522-2586.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24006202.
  • Zeng F, Harris RC. Epidermal growth factor, from gene organization to bedside. Semin. Cell Dev. Biol [print-electronic]. 2014 Apr; 28: 2-11. PMID: 24513230, PMCID: PMC4037350, PII: S1084-9521(14)00013-5, DOI: 10.1016/j.semcdb.2014.01.011, ISSN: 1096-3634.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24513230.
  • Capdevila JH, Pidkovka N, Mei S, Gong Y, Falck JR, Imig JD, Harris RC, Wang W. The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt. J. Biol. Chem [print-electronic]. 2014 Feb 2/14/2014; 289(7): 4377-86. PMID: 24368771, PMCID: PMC3924300, PII: M113.508416, DOI: 10.1074/jbc.M113.508416, ISSN: 1083-351X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24368771.
  • Cheng H, Harris RC. Renal endothelial dysfunction in diabetic nephropathy. Cardiovasc Hematol Disord Drug Targets. 2014; 14(1): 22-33. PMID: 24720460, PMCID: PMC4657140, PII: CHDDT-EPUB-59896, ISSN: 2212-4063.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24720460.
  • Takahashi T, Harris RC. Role of endothelial nitric oxide synthase in diabetic nephropathy: lessons from diabetic eNOS knockout mice. J Diabetes Res [print-electronic]. 2014; 2014: 590541. PMID: 25371905, PMCID: PMC4211249, DOI: 10.1155/2014/590541, ISSN: 2314-6753.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25371905.
  • Trachtman H, Benzing T, Sever S, Harris RC, Reiser J. The grand challenge of nephrology. Front Med (Lausanne). 2014; 1: 28. PMID: 25593903, PMCID: PMC4291843, DOI: 10.3389/fmed.2014.00028, ISSN: 2296-858X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25593903.
  • Trachtman H, Benzing T, Sever S, Harris RC, Reiser J. The grand challenge of nephrology. Front Med (Lausanne). 2014; 1: 28. PMID: 25593903, PMCID: PMC4291843, DOI: 10.3389/fmed.2014.00028.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25593903.
  • Zhang MZ, Wang Y, Yao B, Gewin L, Wei S, Capdevila JH, Harris RC. Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney. Am. J. Physiol. Renal Physiol [print-electronic]. 2013 Dec 12/15/2013; 305(12): F1680-6. PMID: 24154693, PMCID: PMC3882452, PII: ajprenal.00409.2013, DOI: 10.1152/ajprenal.00409.2013, ISSN: 1522-1466.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24154693.
  • Chen J, Chen JK, Conway EM, Harris RC. Survivin mediates renal proximal tubule recovery from AKI. J. Am. Soc. Nephrol [print-electronic]. 2013 Dec; 24(12): 2023-33. PMID: 23949800, PMCID: PMC3839548, PII: ASN.2013010076, DOI: 10.1681/ASN.2013010076, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23949800.
  • Miyazawa T, Zeng F, Wang S, Fan X, Cheng H, Yang H, Bian A, Fogo AB, Harris RC. Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression. Kidney Int [print-electronic]. 2013 Dec; 84(6): 1176-88. PMID: 23760291, PMCID: PMC3796048, PII: S0085-2538(15)56105-X, DOI: 10.1038/ki.2013.214, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23760291.
  • Jiang L, Yang S, Yin H, Fan X, Wang S, Yao B, Pozzi A, Chen X, Harris RC, Zhang MZ. Epithelial-specific deletion of 11ß-HSD2 hinders Apcmin/+ mouse tumorigenesis. Mol. Cancer Res [print-electronic]. 2013 Sep; 11(9): 1040-50. PMID: 23741059, PMCID: PMC3778073, PII: 1541-7786.MCR-13-0084-T, DOI: 10.1158/1541-7786.MCR-13-0084-T, ISSN: 1557-3125.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23741059.
  • Skrypnyk NI, Harris RC, de Caestecker MP. Ischemia-reperfusion model of acute kidney injury and post injury fibrosis in mice. J Vis Exp. 2013 Aug 8/9/2013; (78): PMID: 23963468, PMCID: PMC3854859, DOI: 10.3791/50495, ISSN: 1940-087X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23963468.
  • Atochina-Vasserman EN, Biktasova A, Abramova E, Cheng DS, Polosukhin VV, Tanjore H, Takahashi S, Sonoda H, Foye L, Venkov C, Ryzhov SV, Novitskiy S, Shlonimskaya N, Ikeda M, Blackwell TS, Lawson WE, Gow AJ, Harris RC, Dikov MM, Tchekneva EE. Aquaporin 11 insufficiency modulates kidney susceptibility to oxidative stress. Am. J. Physiol. Renal Physiol [print-electronic]. 2013 May 5/15/2013; 304(10): F1295-307. PMID: 23486012, PMCID: PMC3651623, PII: ajprenal.00344.2012, DOI: 10.1152/ajprenal.00344.2012, ISSN: 1522-1466.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23486012.
  • Harris RC. The best-laid plans [editorial]. Am. J. Physiol. Renal Physiol [print-electronic]. 2013 Apr 4/15/2013; 304(8): F1086-7. PMID: 23269642, PMCID: PMC3625842, PII: ajprenal.00693.2012, DOI: 10.1152/ajprenal.00693.2012, ISSN: 1522-1466.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23269642.
  • Pidkovka N, Rao R, Mei S, Gong Y, Harris RC, Wang WH, Capdevila JH. Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation. J. Biol. Chem [print-electronic]. 2013 Feb 2/15/2013; 288(7): 5223-31. PMID: 23283969, PMCID: PMC3576126, PII: M112.407981, DOI: 10.1074/jbc.M112.407981, ISSN: 1083-351X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23283969.
  • Chen J, Chen MX, Fogo AB, Harris RC, Chen JK. MVps34 deletion in podocytes causes glomerulosclerosis by disrupting intracellular vesicle trafficking. J. Am. Soc. Nephrol [print-electronic]. 2013 Feb; 24(2): 198-207. PMID: 23291473, PMCID: PMC3559479, PII: ASN.2012010101, DOI: 10.1681/ASN.2012010101, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23291473.
  • Harris RC. Physiologic and pathophysiologic roles of cyclooxygenase-2 in the kidney. Trans. Am. Clin. Climatol. Assoc. 2013; 124: 139-51. PMID: 23874018, PMCID: PMC3715909, ISSN: 0065-7778.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23874018.
  • Cheng H, Wang H, Fan X, Paueksakon P, Harris RC. Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice. Kidney Int [print-electronic]. 2012 Dec; 82(11): 1176-83. PMID: 22785174, PMCID: PMC3473143, PII: ki2012248, DOI: 10.1038/ki.2012.248, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22785174.
  • Gewin L, Vadivelu S, Neelisetty S, Srichai MB, Paueksakon P, Pozzi A, Harris RC, Zent R. Deleting the TGF-ß receptor attenuates acute proximal tubule injury. J. Am. Soc. Nephrol [print-electronic]. 2012 Dec; 23(12): 2001-11. PMID: 23160515, PMCID: PMC3507360, PII: ASN.2012020139, DOI: 10.1681/ASN.2012020139, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23160515.
  • Zhang MZ, Yao B, Yang S, Jiang L, Wang S, Fan X, Yin H, Wong K, Miyazawa T, Chen J, Chang I, Singh A, Harris RC. CSF-1 signaling mediates recovery from acute kidney injury. J. Clin. Invest [print-electronic]. 2012 Dec; 122(12): 4519-32. PMID: 23143303, PMCID: PMC3533529, PII: 60363, DOI: 10.1172/JCI60363, ISSN: 1558-8238.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23143303.
  • Bartlett CS, Boyd KL, Harris RC, Zent R, Breyer RM. EP1 disruption attenuates end-organ damage in a mouse model of hypertension. Hypertension [print-electronic]. 2012 Nov; 60(5): 1184-91. PMID: 23006735, PMCID: PMC3478772, PII: HYPERTENSIONAHA.112.199026, DOI: 10.1161/HYPERTENSIONAHA.112.199026, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23006735.
  • Howard C, Tao S, Yang HC, Fogo AB, Woodgett JR, Harris RC, Rao R. Specific deletion of glycogen synthase kinase-3ß in the renal proximal tubule protects against acute nephrotoxic injury in mice. Kidney Int [print-electronic]. 2012 Nov; 82(9): 1000-9. PMID: 22785175, PMCID: PMC3472082, PII: ki2012239, DOI: 10.1038/ki.2012.239, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22785175.
  • Zhang MZ, Yao B, Yang S, Yang H, Wang S, Fan X, Yin H, Fogo AB, Moeckel GW, Harris RC. Intrarenal dopamine inhibits progression of diabetic nephropathy. Diabetes [print-electronic]. 2012 Oct; 61(10): 2575-84. PMID: 22688335, PMCID: PMC3447896, PII: db12-0046, DOI: 10.2337/db12-0046, ISSN: 1939-327X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22688335.
  • Jiang R, Wang S, Takahashi K, Fujita H, Fruci CR, Breyer MD, Harris RC, Takahashi T. Generation of a conditional allele for the mouse endothelial nitric oxide synthase gene. Genesis [print-electronic]. 2012 Sep; 50(9): 685-92. PMID: 22467476, PMCID: PMC3399989, DOI: 10.1002/dvg.22026, ISSN: 1526-968X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22467476.
  • Harris RC. Podocyte ACE2 protects against diabetic nephropathy. Kidney Int. 2012 Aug; 82(3): 255-6. PMID: 22791320, PII: ki2012127, DOI: 10.1038/ki.2012.127, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22791320.
  • Chen J, Chen JK, Harris RC. Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury. Kidney Int [print-electronic]. 2012 Jul; 82(1): 45-52. PMID: 22418982, PMCID: PMC3376190, PII: ki201243, DOI: 10.1038/ki.2012.43, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22418982.
  • Yu L, Su Y, Paueksakon P, Cheng H, Chen X, Wang H, Harris RC, Zent R, Pozzi A. Integrin a1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy. Kidney Int [print-electronic]. 2012 Jun; 81(11): 1086-97. PMID: 22297672, PMCID: PMC3345314, PII: ki2011474, DOI: 10.1038/ki.2011.474, ISSN: 1523-1755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22297672.
  • Harris RC, Zhang MZ. Dopamine, the kidney, and hypertension. Curr. Hypertens. Rep. 2012 Apr; 14(2): 138-43. PMID: 22407378, PMCID: PMC3742329, DOI: 10.1007/s11906-012-0253-z, ISSN: 1534-3111.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22407378.
  • Yang S, Yao B, Zhou Y, Yin H, Zhang MZ, Harris RC. Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury. Am. J. Physiol. Renal Physiol [print-electronic]. 2012 Mar 3/15/2012; 302(6): F742-9. PMID: 22169008, PMCID: PMC3311314, PII: ajprenal.00583.2011, DOI: 10.1152/ajprenal.00583.2011, ISSN: 1522-1466.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22169008.
  • Chen J, Chen JK, Harris RC. Angiotensin II induces epithelial-to-mesenchymal transition in renal epithelial cells through reactive oxygen species/Src/caveolin-mediated activation of an epidermal growth factor receptor-extracellular signal-regulated kinase signaling pathway. Mol. Cell. Biol [print-electronic]. 2012 Mar; 32(5): 981-91. PMID: 22215616, PMCID: PMC3295195, PII: MCB.06410-11, DOI: 10.1128/MCB.06410-11, ISSN: 1098-5549.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22215616.
  • Zhang MZ, Wang S, Yang S, Yang H, Fan X, Takahashi T, Harris RC. Role of blood pressure and the renin-angiotensin system in development of diabetic nephropathy (DN) in eNOS-/- db/db mice. Am. J. Physiol. Renal Physiol [print-electronic]. 2012 Feb 2/15/2012; 302(4): F433-8. PMID: 22114203, PMCID: PMC3289417, PII: ajprenal.00292.2011, DOI: 10.1152/ajprenal.00292.2011, ISSN: 1522-1466.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22114203.
  • Chen J, Chen JK, Nagai K, Plieth D, Tan M, Lee TC, Threadgill DW, Neilson EG, Harris RC. EGFR signaling promotes TGFß-dependent renal fibrosis. J. Am. Soc. Nephrol [print-electronic]. 2012 Feb; 23(2): 215-24. PMID: 22095949, PMCID: PMC3269185, PII: ASN.2011070645, DOI: 10.1681/ASN.2011070645, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22095949.
  • Harris RC. Abnormalities in renal dopamine signaling and hypertension: the role of GRK4. Curr. Opin. Nephrol. Hypertens. 2012 Jan; 21(1): 61-5. PMID: 22123211, PMCID: PMC3286360, DOI: 10.1097/MNH.0b013e32834de2cb, ISSN: 1473-6543.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22123211.
  • Tantawy MN, Jiang R, Wang F, Takahashi K, Peterson TE, Zemel D, Hao CM, Fujita H, Harris RC, Quarles CC, Takahashi T. Assessment of renal function in mice with unilateral ureteral obstruction using 99mTc-MAG3 dynamic scintigraphy. BMC Nephrol. 2012; 13: 168. PMID: 23228112, PMCID: PMC3542003, PII: 1471-2369-13-168, DOI: 10.1186/1471-2369-13-168, ISSN: 1471-2369.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23228112.
  • Harris RC, Zhang MZ. Cyclooxygenase metabolites in the kidney. Compr Physiol. 2011 Oct; 1(4): 1729-58. PMID: 23733687, DOI: 10.1002/cphy.c100077, ISSN: 2040-4603.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23733687.
  • Dhawan P, Ahmad R, Chaturvedi R, Smith JJ, Midha R, Mittal MK, Krishnan M, Chen X, Eschrich S, Yeatman TJ, Harris RC, Washington MK, Wilson KT, Beauchamp RD, Singh AB. Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation. Oncogene [print-electronic]. 2011 Jul 7/21/2011; 30(29): 3234-47. PMID: 21383692, PMCID: PMC3591522, PII: onc201143, DOI: 10.1038/onc.2011.43, ISSN: 1476-5594.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21383692.
  • Cheng H, Fan X, Moeckel GW, Harris RC. Podocyte COX-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression. J. Am. Soc. Nephrol. 2011 Jul; 22(7): 1240-51. PMID: 21737546, PMCID: PMC3137572, PII: 22/7/1240, DOI: 10.1681/ASN.2010111149, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21737546.
  • Zhang MZ, Yao B, Wang S, Fan X, Wu G, Yang H, Yin H, Yang S, Harris RC. Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice. J. Clin. Invest [print-electronic]. 2011 Jul; 121(7): 2845-54. PMID: 21701066, PMCID: PMC3223841, PII: 57324, DOI: 10.1172/JCI57324, ISSN: 1558-8238.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21701066.
  • Cheng H, Harris RC. The glomerulus--a view from the outside--the podocyte. Int. J. Biochem. Cell Biol [print-electronic]. 2010 Sep; 42(9): 1380-7. PMID: 20542138, PMCID: PMC2910191, PII: S1357-2725(10)00194-9, DOI: 10.1016/j.biocel.2010.05.014, ISSN: 1878-5875.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20542138.
  • Gewin L, Bulus N, Mernaugh G, Moeckel G, Harris RC, Moses HL, Pozzi A, Zent R. TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis. J. Am. Soc. Nephrol [print-electronic]. 2010 Aug; 21(8): 1334-43. PMID: 20576806, PMCID: PMC2938601, PII: ASN.2010020147, DOI: 10.1681/ASN.2010020147, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20576806.
  • Chen X, Whiting C, Borza C, Hu W, Mont S, Bulus N, Zhang MZ, Harris RC, Zent R, Pozzi A. Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression. Mol. Cell. Biol [print-electronic]. 2010 Jun; 30(12): 3048-58. PMID: 20368353, PMCID: PMC2876688, PII: MCB.00892-09, DOI: 10.1128/MCB.00892-09, ISSN: 1098-5549.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20368353.
  • Zhang MZ, Su Y, Yao B, Zheng W, Decaestecker M, Harris RC. Assessing the application of tissue microarray technology to kidney research. J. Histochem. Cytochem [print-electronic]. 2010 May; 58(5): 413-20. PMID: 20086233, PMCID: PMC2857813, PII: jhc.2009.954966, DOI: 10.1369/jhc.2009.954966, ISSN: 1551-5044.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20086233.
  • He W, Wang Y, Zhang MZ, You L, Davis LS, Fan H, Yang HC, Fogo AB, Zent R, Harris RC, Breyer MD, Hao CM. Sirt1 activation protects the mouse renal medulla from oxidative injury. J. Clin. Invest [print-electronic]. 2010 Apr; 120(4): 1056-68. PMID: 20335659, PMCID: PMC2846063, PII: 41563, DOI: 10.1172/JCI41563, ISSN: 1558-8238.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/20335659.
  • Ray KC, Blaine SA, Washington MK, Braun AH, Singh AB, Harris RC, Harding PA, Coffey RJ, Means AL. Transmembrane and soluble isoforms of heparin-binding epidermal growth factor-like growth factor regulate distinct processes in the pancreas. Gastroenterology [print-electronic]. 2009 Nov; 137(5): 1785-94. PMID: 19689925, PMCID: PMC2767440, PII: S0016-5085(09)01399-7, DOI: 10.1053/j.gastro.2009.07.067, ISSN: 1528-0012.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19689925.
  • Yao B, Harris RC, Zhang MZ. Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway. Hypertension [print-electronic]. 2009 Nov; 54(5): 1077-83. PMID: 19770404, PMCID: PMC2782522, PII: HYPERTENSIONAHA.109.137174, DOI: 10.1161/HYPERTENSIONAHA.109.137174, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19770404.
  • Zhang X, Mernaugh G, Yang DH, Gewin L, Srichai MB, Harris RC, Iturregui JM, Nelson RD, Kohan DE, Abrahamson D, Fässler R, Yurchenco P, Pozzi A, Zent R. Beta1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity. Development [print-electronic]. 2009 Oct; 136(19): 3357-66. PMID: 19710172, PMCID: PMC2739149, PII: dev.036269, DOI: 10.1242/dev.036269, ISSN: 1477-9129.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19710172.
  • Cheng H, Fan X, Guan Y, Moeckel GW, Zent R, Harris RC. Distinct roles for basal and induced COX-2 in podocyte injury. J. Am. Soc. Nephrol [print-electronic]. 2009 Sep; 20(9): 1953-62. PMID: 19643929, PMCID: PMC2736764, PII: ASN.2009010039, DOI: 10.1681/ASN.2009010039, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19643929.
  • Zeng F, Xu J, Harris RC. Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells. FASEB J [print-electronic]. 2009 Jun; 23(6): 1935-45. PMID: 19193720, PMCID: PMC2698660, PII: fj.08-121947, DOI: 10.1096/fj.08-121947, ISSN: 1530-6860.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19193720.
  • Smith JP, Pozzi A, Dhawan P, Singh AB, Harris RC. Soluble HB-EGF induces epithelial-to-mesenchymal transition in inner medullary collecting duct cells by upregulating Snail-2. Am. J. Physiol. Renal Physiol [print-electronic]. 2009 May; 296(5): F957-65. PMID: 19244405, PMCID: PMC2681361, PII: 90490.2008, DOI: 10.1152/ajprenal.90490.2008, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19244405.
  • Zhang MZ, Xu J, Yao B, Yin H, Cai Q, Shrubsole MJ, Chen X, Kon V, Zheng W, Pozzi A, Harris RC. Inhibition of 11beta-hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans. J. Clin. Invest [print-electronic]. 2009 Apr; 119(4): 876-85. PMID: 19307727, PMCID: PMC2662561, PII: 37398, DOI: 10.1172/JCI37398, ISSN: 1558-8238.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19307727.
  • Zhang MZ, Yao B, Fang X, Wang S, Smith JP, Harris RC. Intrarenal dopaminergic system regulates renin expression. Hypertension [print-electronic]. 2009 Mar; 53(3): 564-70. PMID: 19139376, PMCID: PMC2680004, PII: HYPERTENSIONAHA.108.127035, DOI: 10.1161/HYPERTENSIONAHA.108.127035, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19139376.
  • Zeng F, Singh AB, Harris RC. The role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology. Exp. Cell Res [print-electronic]. 2009 Feb 2/15/2009; 315(4): 602-10. PMID: 18761338, PMCID: PMC2654782, PII: S0014-4827(08)00316-9, DOI: 10.1016/j.yexcr.2008.08.005, ISSN: 1090-2422.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18761338.
  • Han BG, Hao CM, Tchekneva EE, Wang YY, Lee CA, Ebrahim B, Harris RC, Kern TS, Wasserman DH, Breyer MD, Qi Z. Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c. Am. J. Physiol. Endocrinol. Metab [print-electronic]. 2008 Oct; 295(4): E981-6. PMID: 18664598, PMCID: PMC2575908, PII: 90283.2008, DOI: 10.1152/ajpendo.90283.2008, ISSN: 0193-1849.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18664598.
  • Tchekneva EE, Khuchua Z, Davis LS, Kadkina V, Dunn SR, Bachman S, Ishibashi K, Rinchik EM, Harris RC, Dikov MM, Breyer MD. Single amino acid substitution in aquaporin 11 causes renal failure. J. Am. Soc. Nephrol [print-electronic]. 2008 Oct; 19(10): 1955-64. PMID: 18701606, PMCID: PMC2551576, PII: ASN.2008030296, DOI: 10.1681/ASN.2008030296, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18701606.
  • Chen JK, Chen J, Imig JD, Wei S, Hachey DL, Guthi JS, Falck JR, Capdevila JH, Harris RC. Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors. J. Biol. Chem [print-electronic]. 2008 Sep 9/5/2008; 283(36): 24514-24. PMID: 18606824, PMCID: PMC2528993, PII: M709873200, DOI: 10.1074/jbc.M709873200, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18606824.
  • Srichai MB, Hao C, Davis L, Golovin A, Zhao M, Moeckel G, Dunn S, Bulus N, Harris RC, Zent R, Breyer MD. Apoptosis of the thick ascending limb results in acute kidney injury. J. Am. Soc. Nephrol [print-electronic]. 2008 Aug; 19(8): 1538-46. PMID: 18495962, PMCID: PMC2488270, PII: ASN.2007101101, DOI: 10.1681/ASN.2007101101, ISSN: 1533-3450.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18495962.
  • Pozzi A, Jarad G, Moeckel GW, Coffa S, Zhang X, Gewin L, Eremina V, Hudson BG, Borza DB, Harris RC, Holzman LB, Phillips CL, Fassler R, Quaggin SE, Miner JH, Zent R. Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev. Biol [print-electronic]. 2008 Apr 4/15/2008; 316(2): 288-301. PMID: 18328474, PMCID: PMC2396524, PII: S0012-1606(08)00039-0, DOI: 10.1016/j.ydbio.2008.01.022, ISSN: 1095-564X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18328474.
  • Yao B, Xu J, Harris RC, Zhang MZ. Renal localization and regulation of 15-hydroxyprostaglandin dehydrogenase. Am. J. Physiol. Renal Physiol [print-electronic]. 2008 Feb; 294(2): F433-9. PMID: 18057186, PII: 00436.2007, DOI: 10.1152/ajprenal.00436.2007, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18057186.
  • Harris RC. An update on cyclooxygenase-2 expression and metabolites in the kidney. Curr. Opin. Nephrol. Hypertens. 2008 Jan; 17(1): 64-9. PMID: 18090672, PII: 00041552-200801000-00011, DOI: 10.1097/MNH.0b013e3282f1bb7d, ISSN: 1062-4821.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18090672.
  • Singh AB, Sugimoto K, Harris RC. Juxtacrine activation of epidermal growth factor (EGF) receptor by membrane-anchored heparin-binding EGF-like growth factor protects epithelial cells from anoikis while maintaining an epithelial phenotype. J. Biol. Chem [print-electronic]. 2007 Nov 11/9/2007; 282(45): 32890-901. PMID: 17848576, PII: M702677200, DOI: 10.1074/jbc.M702677200, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17848576.
  • Singh AB, Sugimoto K, Dhawan P, Harris RC. Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance. Am. J. Physiol., Cell Physiol [print-electronic]. 2007 Nov; 293(5): C1660-8. PMID: 17855771, PII: 00274.2007, DOI: 10.1152/ajpcell.00274.2007, ISSN: 0363-6143.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17855771.
  • Xu J, Yao B, Fan X, Langworthy MM, Zhang MZ, Harris RC. Characterization of a putative intrarenal serotonergic system. Am. J. Physiol. Renal Physiol [print-electronic]. 2007 Nov; 293(5): F1468-75. PMID: 17715266, PII: 00246.2007, DOI: 10.1152/ajprenal.00246.2007, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17715266.
  • Zeng F, Zhang MZ, Singh AB, Zent R, Harris RC. ErbB4 isoforms selectively regulate growth factor induced Madin-Darby canine kidney cell tubulogenesis. Mol. Biol. Cell [print-electronic]. 2007 Nov; 18(11): 4446-56. PMID: 17761534, PMCID: PMC2043549, PII: E07-03-0223, DOI: 10.1091/mbc.E07-03-0223, ISSN: 1059-1524.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17761534.
  • Chen X, Abair TD, Ibanez MR, Su Y, Frey MR, Dise RS, Polk DB, Singh AB, Harris RC, Zent R, Pozzi A. Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation. Mol. Cell. Biol [print-electronic]. 2007 May; 27(9): 3313-26. PMID: 17339338, PMCID: PMC1899972, PII: MCB.01476-06, DOI: 10.1128/MCB.01476-06, ISSN: 0270-7306.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17339338.
  • Kanetsuna Y, Takahashi K, Nagata M, Gannon MA, Breyer MD, Harris RC, Takahashi T. Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice. Am. J. Pathol. 2007 May; 170(5): 1473-84. PMID: 17456755, PMCID: PMC1854944, PII: S0002-9440(10)61362-4, DOI: 10.2353/ajpath.2007.060481, ISSN: 0002-9440.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17456755.
  • Chen J, Chen JK, Falck JR, Guthi JS, Anjaiah S, Capdevila JH, Harris RC. Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite. Mol. Cell. Biol [print-electronic]. 2007 Apr; 27(8): 3023-34. PMID: 17283047, PMCID: PMC1899952, PII: MCB.01482-06, DOI: 10.1128/MCB.01482-06, ISSN: 0270-7306.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17283047.
  • Breyer MD, Tchekneva E, Qi Z, Takahashi T, Fogo AB, Zhao HJ, Harris RC. Genetics of diabetic nephropathy: lessons from mice. Semin. Nephrol. 2007 Mar; 27(2): 237-47. PMID: 17418691, PII: S0270-9295(07)00002-2, DOI: 10.1016/j.semnephrol.2007.01.001, ISSN: 0270-9295.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17418691.
  • Cheng H, Wang S, Jo YI, Hao CM, Zhang M, Fan X, Kennedy C, Breyer MD, Moeckel GW, Harris RC. Overexpression of cyclooxygenase-2 predisposes to podocyte injury. J. Am. Soc. Nephrol [print-electronic]. 2007 Feb; 18(2): 551-9. PMID: 17202413, PII: ASN.2006090990, DOI: 10.1681/ASN.2006090990, ISSN: 1046-6673.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17202413.
  • Jo YI, Cheng H, Wang S, Moeckel GW, Harris RC. Puromycin induces reversible proteinuric injury in transgenic mice expressing cyclooxygenase-2 in podocytes. Nephron Exp. Nephrol [print-electronic]. 2007; 107(3): e87-94. PMID: 17890881, PII: 000108653, DOI: 10.1159/000108653, ISSN: 1660-2129.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17890881.
  • Kanetsuna Y, Hirano K, Nagata M, Gannon MA, Takahashi K, Harris RC, Breyer MD, Takahashi T. Characterization of diabetic nephropathy in a transgenic model of hypoinsulinemic diabetes. Am. J. Physiol. Renal Physiol [print-electronic]. 2006 Dec; 291(6): F1315-22. PMID: 16705146, PII: 00379.2005, DOI: 10.1152/ajprenal.00379.2005, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16705146.
  • Zhang MZ, Yao B, Cheng HF, Wang SW, Inagami T, Harris RC. Renal cortical cyclooxygenase 2 expression is differentially regulated by angiotensin II AT(1) and AT(2) receptors. Proc. Natl. Acad. Sci. U.S.A [print-electronic]. 2006 Oct 10/24/2006; 103(43): 16045-50. PMID: 17043228, PMCID: PMC1635124, PII: 0602176103, DOI: 10.1073/pnas.0602176103, ISSN: 0027-8424.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17043228.
  • Zhao HJ, Wang S, Cheng H, Zhang MZ, Takahashi T, Fogo AB, Breyer MD, Harris RC. Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice. J. Am. Soc. Nephrol [print-electronic]. 2006 Oct; 17(10): 2664-9. PMID: 16971655, PMCID: PMC4618687, PII: ASN.2006070798, DOI: 10.1681/ASN.2006070798, ISSN: 1046-6673.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16971655.
  • Cheng H, Harris RC. Potential side effects of renin inhibitors--mechanisms based on comparison with other renin-angiotensin blockers. Expert Opin Drug Saf. 2006 Sep; 5(5): 631-41. PMID: 16907653, DOI: 10.1517/14740338.5.5.631, ISSN: 1744-764X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16907653.
  • Yao B, Xu J, Qi Z, Harris RC, Zhang MZ. Role of renal cortical cyclooxygenase-2 expression in hyperfiltration in rats with high-protein intake. Am. J. Physiol. Renal Physiol [print-electronic]. 2006 Aug; 291(2): F368-74. PMID: 16597606, PII: 00500.2005, DOI: 10.1152/ajprenal.00500.2005, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16597606.
  • Chen J, Chen JK, Neilson EG, Harris RC. Role of EGF receptor activation in angiotensin II-induced renal epithelial cell hypertrophy. J. Am. Soc. Nephrol [print-electronic]. 2006 Jun; 17(6): 1615-23. PMID: 16641152, PII: ASN.2005111163, DOI: 10.1681/ASN.2005111163, ISSN: 1046-6673.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16641152.
  • Cheng HF, Zhang MZ, Harris RC. Nitric oxide stimulates cyclooxygenase-2 in cultured cTAL cells through a p38-dependent pathway. Am. J. Physiol. Renal Physiol [print-electronic]. 2006 Jun; 290(6): F1391-7. PMID: 16380459, PII: 00315.2005, DOI: 10.1152/ajprenal.00315.2005, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16380459.
  • Harris RC, Breyer MD. Update on cyclooxygenase-2 inhibitors. Clin J Am Soc Nephrol [print-electronic]. 2006 Mar; 1(2): 236-45. PMID: 17699212, PII: CJN.00890805, DOI: 10.2215/CJN.00890805, ISSN: 1555-905X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17699212.
  • Harris RC, Neilson EG. Toward a unified theory of renal progression. Annu. Rev. Med. 2006; 57: 365-80. PMID: 16409155, DOI: 10.1146/annurev.med.57.121304.131342, ISSN: 0066-4219.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16409155.
  • Harris RC. COX-2 and the kidney. J. Cardiovasc. Pharmacol. 2006; 47 Suppl 1: S37-42. PMID: 16785827, PII: 00005344-200605001-00007, ISSN: 0160-2446.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16785827.
  • Singh AB, Harris RC. Autocrine, paracrine and juxtacrine signaling by EGFR ligands. Cell. Signal. 2005 Oct; 17(10): 1183-93. PMID: 15982853, PII: S0898-6568(05)00076-8, DOI: 10.1016/j.cellsig.2005.03.026, ISSN: 0898-6568.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15982853.
  • Yao B, Harris RC, Zhang MZ. Interactions between 11beta-hydroxysteroid dehydrogenase and COX-2 in kidney. Am. J. Physiol. Regul. Integr. Comp. Physiol [print-electronic]. 2005 Jun; 288(6): R1767-73. PMID: 15718388, PII: 00786.2004, DOI: 10.1152/ajpregu.00786.2004, ISSN: 0363-6119.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15718388.
  • Chen JK, Chen J, Neilson EG, Harris RC. Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy. J. Am. Soc. Nephrol [print-electronic]. 2005 May; 16(5): 1384-91. PMID: 15788477, PII: ASN.2004100894, DOI: 10.1681/ASN.2004100894, ISSN: 1046-6673.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15788477.
  • Shivakumar BR, Wang Z, Hammond TG, Harris RC. EP24.15 interacts with the angiotensin II type I receptor and bradykinin B2 receptor. Cell Biochem. Funct. 2005 May; 23(3): 195-204. PMID: 15376229, DOI: 10.1002/cbf.1176, ISSN: 0263-6484.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15376229.
  • Breyer MD, Böttinger E, Brosius FC, Coffman TM, Fogo A, Harris RC, Heilig CW, Sharma K. Diabetic nephropathy: of mice and men. Adv Chronic Kidney Dis. 2005 Apr; 12(2): 128-45. PMID: 15822049, PII: S1548559505000285, ISSN: 1548-5595.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15822049.
  • Rao R, Zhang MZ, Zhao M, Cai H, Harris RC, Breyer MD, Hao CM. Lithium treatment inhibits renal GSK-3 activity and promotes cyclooxygenase 2-dependent polyuria. Am. J. Physiol. Renal Physiol [print-electronic]. 2005 Apr; 288(4): F642-9. PMID: 15585669, PII: 00287.2004, DOI: 10.1152/ajprenal.00287.2004, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15585669.
  • Zhang MZ, Yao B, McKanna JA, Harris RC. Cross talk between the intrarenal dopaminergic and cyclooxygenase-2 systems. Am. J. Physiol. Renal Physiol [print-electronic]. 2005 Apr; 288(4): F840-5. PMID: 15613619, PII: 00240.2004, DOI: 10.1152/ajprenal.00240.2004, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15613619.
  • Breyer MD, Böttinger E, Brosius FC, Coffman TM, Harris RC, Heilig CW, Sharma K, . Mouse models of diabetic nephropathy. J. Am. Soc. Nephrol [print-electronic]. 2005 Jan; 16(1): 27-45. PMID: 15563560, PII: ASN.2004080648, DOI: 10.1681/ASN.2004080648, ISSN: 1046-6673.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15563560.
  • Cheng H, Zhang M, Moeckel GW, Zhao Y, Wang S, Qi Z, Breyer MD, Harris RC. Expression of mediators of renal injury in the remnant kidney of ROP mice is attenuated by cyclooxygenase-2 inhibition. Nephron Exp. Nephrol [print-electronic]. 2005; 101(3): e75-85. PMID: 15995341, PII: 86645, DOI: 10.1159/000086645, ISSN: 1660-2129.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15995341.
  • Cheng HF, Harris RC. Renal effects of non-steroidal anti-inflammatory drugs and selective cyclooxygenase-2 inhibitors. Curr. Pharm. Des. 2005; 11(14): 1795-804. PMID: 15892676, ISSN: 1381-6128.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15892676.
  • Chen D, Roberts R, Pohl M, Nigam S, Kreidberg J, Wang Z, Heino J, Ivaska J, Coffa S, Harris RC, Pozzi A, Zent R. Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis. Am. J. Physiol. Renal Physiol [print-electronic]. 2004 Oct; 287(4): F602-11. PMID: 15187002, PII: 00015.2004, DOI: 10.1152/ajprenal.00015.2004, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15187002.
  • Fisher ME, Rossini M, Simmons E, Harris RC, Moeckel G, Zent R. A woman with chronic hepatitis C infection and nephrotic syndrome who developed multiple renal lesions after interferon alfa therapy. Am. J. Kidney Dis. 2004 Sep; 44(3): 567-73. PMID: 15332232, PII: S0272638604008285, ISSN: 1523-6838.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15332232.
  • Chen X, Moeckel G, Morrow JD, Cosgrove D, Harris RC, Fogo AB, Zent R, Pozzi A. Lack of integrin alpha1beta1 leads to severe glomerulosclerosis after glomerular injury. Am. J. Pathol. 2004 Aug; 165(2): 617-30. PMID: 15277235, PMCID: PMC1618576, PII: S0002-9440(10)63326-3, ISSN: 0002-9440.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15277235.
  • Harris RC, Zhang MZ, Cheng HF. Cyclooxygenase-2 and the renal renin-angiotensin system. Acta Physiol. Scand. 2004 Aug; 181(4): 543-7. PMID: 15283769, PII: APS1329, DOI: 10.1111/j.1365-201X.2004.01329.x, ISSN: 0001-6772.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/15283769.
  • Singh AB, Tsukada T, Zent R, Harris RC. Membrane-associated HB-EGF modulates HGF-induced cellular responses in MDCK cells. J. Cell. Sci [print-electronic]. 2004 Mar 3/15/2004; 117(Pt 8): 1365-79. PMID: 14996914, PII: jcs.01037, DOI: 10.1242/jcs.01037, ISSN: 0021-9533.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14996914.
  • Cheng HF, Harris RC. Cyclooxygenases, the kidney, and hypertension. Hypertension [print-electronic]. 2004 Mar; 43(3): 525-30. PMID: 14732722, PII: 01.HYP.0000116221.27079.ea, DOI: 10.1161/01.HYP.0000116221.27079.ea, ISSN: 1524-4563.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14732722.
  • Qi Z, Whitt I, Mehta A, Jin J, Zhao M, Harris RC, Fogo AB, Breyer MD. Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance. Am. J. Physiol. Renal Physiol [print-electronic]. 2004 Mar; 286(3): F590-6. PMID: 14600035, PII: 00324.2003, DOI: 10.1152/ajprenal.00324.2003, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14600035.
  • Zhang MZ, Sanchez Lopez P, McKanna JA, Harris RC. Regulation of cyclooxygenase expression by vasopressin in rat renal medulla. Endocrinology [print-electronic]. 2004 Mar; 145(3): 1402-9. PMID: 14684611, PII: en.2003-0903, DOI: 10.1210/en.2003-0903, ISSN: 0013-7227.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14684611.
  • Zhang MZ, Mai W, Li C, Cho SY, Hao C, Moeckel G, Zhao R, Kim I, Wang J, Xiong H, Wang H, Sato Y, Wu Y, Nakanuma Y, Lilova M, Pei Y, Harris RC, Li S, Coffey RJ, Sun L, Wu D, Chen XZ, Breyer MD, Zhao ZJ, McKanna JA, Wu G. PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 2004 Feb 2/24/2004; 101(8): 2311-6. PMID: 14983006, PMCID: PMC356947, PII: 101/8/2311, ISSN: 0027-8424.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14983006.
  • Singh AB, Harris RC. Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells. J. Biol. Chem [print-electronic]. 2004 Jan 1/30/2004; 279(5): 3543-52. PMID: 14593119, PII: M308682200, DOI: 10.1074/jbc.M308682200, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14593119.
  • Wang Z, Chen JK, Wang SW, Moeckel G, Harris RC. Importance of functional EGF receptors in recovery from acute nephrotoxic injury. J. Am. Soc. Nephrol. 2003 Dec; 14(12): 3147-54. PMID: 14638913, ISSN: 1046-6673.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/14638913.
  • Zhang MZ, Wang SW, Cheng H, Zhang Y, McKanna JA, Harris RC. Regulation of renal cortical cyclooxygenase-2 in young rats. Am. J. Physiol. Renal Physiol [print-electronic]. 2003 Nov; 285(5): F881-8. PMID: 12851252, PII: 00154.2003, DOI: 10.1152/ajprenal.00154.2003, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12851252.
  • Harris RC. Interactions between COX-2 and the renin-angiotensin system in the kidney. Acta Physiol. Scand. 2003 Apr; 177(4): 423-7. PMID: 12648159, PII: 1101, DOI: 10.1046/j.1365-201X.2003.01101.x, ISSN: 0001-6772.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12648159.
  • Means AL, Ray KC, Singh AB, Washington MK, Whitehead RH, Harris RC, Wright CV, Coffey RJ, Leach SD. Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia. Gastroenterology. 2003 Apr; 124(4): 1020-36. PMID: 12671899, PII: S0016508503000647, DOI: 10.1053/gast.2003.50150, ISSN: 0016-5085.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12671899.
  • Harris RC, Chung E, Coffey RJ. EGF receptor ligands. Exp. Cell Res. 2003 Mar 3/10/2003; 284(1): 2-13. PMID: 12648462, PII: S0014482702001052, ISSN: 0014-4827.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12648462.
  • Cheng HF, Harris RC. Does cyclooxygenase-2 affect blood pressure?. Curr. Hypertens. Rep. 2003 Feb; 5(1): 87-92. PMID: 12530941, ISSN: 1522-6417.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12530941.
  • Cheng HF, Harris RC. Cyclooxygenase-2 expression in cultured cortical thick ascending limb of Henle increases in response to decreased extracellular ionic content by both transcriptional and post-transcriptional mechanisms. Role of p38-mediated pathways. J. Biol. Chem [print-electronic]. 2002 Nov 11/22/2002; 277(47): 45638-43. PMID: 12237297, PII: M206040200, DOI: 10.1074/jbc.M206040200, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12237297.
  • Cheng HF, Wang CJ, Moeckel GW, Zhang MZ, McKanna JA, Harris RC. Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension. Kidney Int. 2002 Sep; 62(3): 929-39. PMID: 12164875, PII: kid520, DOI: 10.1046/j.1523-1755.2002.00520.x, ISSN: 0085-2538.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12164875.
  • Cheng HF, Wang SW, Zhang MZ, McKanna JA, Breyer R, Harris RC. Prostaglandins that increase renin production in response to ACE inhibition are not derived from cyclooxygenase-1. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002 Sep; 283(3): R638-46. PMID: 12184998, DOI: 10.1152/ajpregu.00150.2002, ISSN: 0363-6119.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12184998.
  • Harris RC. Cyclooxygenase-2 and the kidney: functional and pathophysiological implications. J Hypertens Suppl. 2002 Sep; 20(6): S3-9. PMID: 12683421, ISSN: 0952-1178.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12683421.
  • Zhang MZ, Hao CM, Breyer MD, Harris RC, McKanna JA. Mineralocorticoid regulation of cyclooxygenase-2 expression in rat renal medulla. Am. J. Physiol. Renal Physiol. 2002 Sep; 283(3): F509-16. PMID: 12167602, DOI: 10.1152/ajprenal.00236.2001, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12167602.
  • Capdevila JH, Harris RC, Falck JR. Microsomal cytochrome P450 and eicosanoid metabolism. Cell. Mol. Life Sci. 2002 May; 59(5): 780-9. PMID: 12088278, ISSN: 1420-682X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/12088278.
  • Chen JK, Capdevila J, Harris RC. Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 2002 Apr 4/30/2002; 99(9): 6029-34. PMID: 11983897, PMCID: PMC122896, PII: 99/9/6029, DOI: 10.1073/pnas.092671899, ISSN: 0027-8424.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11983897.
  • Burleigh ME, Babaev VR, Oates JA, Harris RC, Gautam S, Riendeau D, Marnett LJ, Morrow JD, Fazio S, Linton MF. Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice. Circulation. 2002 Apr 4/16/2002; 105(15): 1816-23. PMID: 11956125, ISSN: 1524-4539.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11956125.
  • Harris RC. Cyclooxygenase-2 inhibition and renal physiology. Am. J. Cardiol. 2002 Mar 3/21/2002; 89(6A): 10D-17D. PMID: 11909556, PII: S0002914902022324, ISSN: 0002-9149.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11909556.
  • Chen JK, Capdevila J, Harris RC. Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis. Mol. Cell. Biol. 2001 Sep; 21(18): 6322-31. PMID: 11509673, PMCID: PMC87364, ISSN: 0270-7306.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11509673.
  • Harris RC, Breyer MD. Physiological regulation of cyclooxygenase-2 in the kidney. Am. J. Physiol. Renal Physiol. 2001 Jul; 281(1): F1-11. PMID: 11399641, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11399641.
  • Cheng HF, Wang JL, Zhang MZ, Wang SW, McKanna JA, Harris RC. Genetic deletion of COX-2 prevents increased renin expression in response to ACE inhibition. Am. J. Physiol. Renal Physiol. 2001 Mar; 280(3): F449-56. PMID: 11181406, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11181406.
  • Breyer MD, Harris RC. Cyclooxygenase 2 and the kidney. Curr. Opin. Nephrol. Hypertens. 2001 Jan; 10(1): 89-98. PMID: 11195058, ISSN: 1062-4821.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11195058.
  • Chen, J-K, Zimpelmann, J., Harris, R.C. and Burns, K.D. Angiotensin IV induces tyrosine phosphorylation of focal adhesion kinase and paxillin in proximal tubule cells. Am. J. Physiol. 2001; 280.
  • Sakai, M. Tsukada, T. and Harris, R.C. Induction of HB-EGF expression by reactive oxygen species: role of AP-1-mediated transcriptional activation. Experimental Nephrology. 2001; 9: 28-30.
  • Takemura, T., Hino, S., Kuwajima, H., Yanagida, H, Okada, M., Nagata, M, Sasaki, S., Barasch, J., Harris, R.C. and Yoshioka, K. Induction of collecting duct morphogenesis in vitro by heparin-binding EGF-like growth factor. J.A.S.N. 2001; 12: 964-72.
  • Harris RC. Cyclooxygenase-2 in the kidney. J. Am. Soc. Nephrol. 2000 Dec; 11(12): 2387-94. PMID: 11095663, ISSN: 1046-6673.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/11095663.
  • Cheng HF, Wang JL, Zhang MZ, McKanna JA, Harris RC. Role of p38 in the regulation of renal cortical cyclooxygenase-2 expression by extracellular chloride. J. Clin. Invest. 2000 Sep; 106(5): 681-8. PMID: 10974021, PMCID: PMC381289, DOI: 10.1172/JCI10318, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10974021.
  • Cheng HF, Wang JL, Zhang MZ, McKanna JA, Harris RC. Nitric oxide regulates renal cortical cyclooxygenase-2 expression. Am. J. Physiol. Renal Physiol. 2000 Jul; 279(1): F122-9. PMID: 10894794, ISSN: 1931-857X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10894794.
  • Wang JL, Cheng HF, Shappell S, Harris RC. A selective cyclooxygenase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats. Kidney Int. 2000 Jun; 57(6): 2334-42. PMID: 10844603, PII: 093, DOI: 10.1046/j.1523-1755.2000.00093.x, ISSN: 0085-2538.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10844603.
  • Chen JK, Capdevila J, Harris RC. Overexpression of C-terminal Src kinase blocks 14, 15-epoxyeicosatrienoic acid-induced tyrosine phosphorylation and mitogenesis. J. Biol. Chem. 2000 May 5/5/2000; 275(18): 13789-92. PMID: 10788500, PII: 275/18/13789, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10788500.
  • Capdevila JH, Falck JR, Harris RC. Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase. J. Lipid Res. 2000 Feb; 41(2): 163-81. PMID: 10681399, ISSN: 0022-2275.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10681399.
  • Haralson MA, DiMari SJ, Hoover RL, Harris RC. Effects of epidermal growth factor on collagen expression by rat kidney mesangial cells in culture. Matrix Biol. 2000 Feb; 19(1): 47-59. PMID: 10686425, PII: S0945-053X(99)00057-8, ISSN: 0945-053X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10686425.
  • Kömhoff M, Wang JL, Cheng HF, Langenbach R, McKanna JA, Harris RC, Breyer MD. Cyclooxygenase-2-selective inhibitors impair glomerulogenesis and renal cortical development. Kidney Int. 2000 Feb; 57(2): 414-22. PMID: 10652018, PII: kid861, DOI: 10.1046/j.1523-1755.2000.00861.x, ISSN: 0085-2538.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10652018.
  • Harris RC, Cheng H, Wang J, Zhang M, McKanna JA. Interactions of the renin-angiotensin system and neuronal nitric oxide synthase in regulation of cyclooxygenase-2 in the macula densa. Acta Physiol. Scand. 2000 Jan; 168(1): 47-51. PMID: 10691779, PII: aps642, DOI: 10.1046/j.1365-201x.2000.00642.x, ISSN: 0001-6772.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10691779.
  • Zhang MZ, Harris RC, McKanna JA. Regulation of cyclooxygenase-2 (COX-2) in rat renal cortex by adrenal glucocorticoids and mineralocorticoids. Proc. Natl. Acad. Sci. U.S.A. 1999 Dec 12/21/1999; 96(26): 15280-5. PMID: 10611376, PMCID: PMC24811, ISSN: 0027-8424.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10611376.
  • Harris RC. Potential mechanisms and physiologic actions of intracellular angiotensin II. Am. J. Med. Sci. 1999 Dec; 318(6): 374-9. PMID: 10616162, ISSN: 0002-9629.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10616162.
  • Becker BN, Kondo S, Chen JK, Harris RC. Tyrosine kinase inhibition affects type 1 angiotensin II receptor internalization. J. Recept. Signal Transduct. Res. 1999 Nov; 19(6): 975-93. PMID: 10533984, DOI: 10.3109/10799899909038435, ISSN: 1079-9893.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10533984.
  • Wang JL, Cheng HF, Harris RC. Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension. Hypertension. 1999 Jul; 34(1): 96-101. PMID: 10406830, ISSN: 0194-911X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10406830.
  • Cheng HF, Wang JL, Zhang MZ, Miyazaki Y, Ichikawa I, McKanna JA, Harris RC. Angiotensin II attenuates renal cortical cyclooxygenase-2 expression. J. Clin. Invest. 1999 Apr; 103(7): 953-61. PMID: 10194467, PMCID: PMC408259, DOI: 10.1172/JCI5505, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10194467.
  • Chen JK, Wang DW, Falck JR, Capdevila J, Harris RC. Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor. J. Biol. Chem. 1999 Feb 2/19/1999; 274(8): 4764-9. PMID: 9988714, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9988714.
  • Takemura T, Hino S, Murata Y, Yanagida H, Okada M, Yoshioka K, Harris RC. Coexpression of CD9 augments the ability of membrane-bound heparin-binding epidermal growth factor-like growth factor (proHB-EGF) to preserve renal epithelial cell viability. Kidney Int. 1999 Jan; 55(1): 71-81. PMID: 9893115, DOI: 10.1046/j.1523-1755.1999.00259.x, ISSN: 0085-2538.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9893115.
  • Gibbs SR, Goins RA, Belvin EL, Dimari SJ, Merriam AP, Bowling-Brown S, Harris RC, Haralson MA. Characterization of the collagen phenotype of rabbit proximal tubule cells in culture. Connect. Tissue Res. 1999; 40(3): 173-88. PMID: 10772539, ISSN: 0300-8207.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/10772539.
  • Chen JK, Falck JR, Reddy KM, Capdevila J, Harris RC. Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells. J. Biol. Chem. 1998 Oct 10/30/1998; 273(44): 29254-61. PMID: 9786938, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9786938.
  • Miyazaki Y, Tsuchida S, Nishimura H, Pope JC, Harris RC, McKanna JM, Inagami T, Hogan BL, Fogo A, Ichikawa I. Angiotensin induces the urinary peristaltic machinery during the perinatal period. J. Clin. Invest. 1998 Oct 10/15/1998; 102(8): 1489-97. PMID: 9788961, PMCID: PMC508998, DOI: 10.1172/JCI4401, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9788961.
  • Wang JL, Cheng HF, Zhang MZ, McKanna JA, Harris RC. Selective increase of cyclooxygenase-2 expression in a model of renal ablation. Am. J. Physiol. 1998 Oct; 275(4 Pt 2): F613-22. PMID: 9755133, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9755133.
  • Harris RC, Wang JL, Cheng HF, Zhang MZ, McKanna JA. Prostaglandins in macula densa function. Kidney Int. Suppl. 1998 Sep; 67: S49-52. PMID: 9736253, ISSN: 0098-6577.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9736253.
  • McKanna JA, Zhang MZ, Wang JL, Cheng H, Harris RC. Constitutive expression of cyclooxygenase-2 in rat vas deferens. Am. J. Physiol. 1998 Jul; 275(1 Pt 2): R227-33. PMID: 9688983, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9688983.
  • Becker BN, Yasuda T, Kondo S, Vaikunth S, Homma T, Harris RC. Mechanical stretch/relaxation stimulates a cellular renin-angiotensin system in cultured rat mesangial cells. Exp. Nephrol. 1998 Jan; 6(1): 57-66. PMID: 9523174, PII: exn06057, ISSN: 1018-7782.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9523174.
  • Cheng HF, Wang JL, Vinson GP, Harris RC. Young SHR express increased type 1 angiotensin II receptors in renal proximal tubule. Am. J. Physiol. 1998 Jan; 274(1 Pt 2): F10-7. PMID: 9458818, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9458818.
  • Takemura T, Kondo S, Homma T, Sakai M, Harris RC. The membrane-bound form of heparin-binding epidermal growth factor-like growth factor promotes survival of cultured renal epithelial cells. J. Biol. Chem. 1997 Dec 12/5/1997; 272(49): 31036-42. PMID: 9388253, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9388253.
  • Zhang MZ, Wang JL, Cheng HF, Harris RC, McKanna JA. Cyclooxygenase-2 in rat nephron development. Am. J. Physiol. 1997 Dec; 273(6 Pt 2): F994-1002. PMID: 9435689, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9435689.
  • Becker BN, Cheng HF, Harris RC. Apical ANG II-stimulated PLA2 activity and Na+ flux: a potential role for Ca2+-independent PLA2. Am. J. Physiol. 1997 Oct; 273(4 Pt 2): F554-62. PMID: 9362333, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9362333.
  • Becker BN, Kondo S, Cheng HF, Harris RC. Effect of glucose, pyruvate, and insulin on type 1 angiotensin II receptor expression in SV40-immortalized rabbit proximal tubule epithelial cells. Kidney Int. 1997 Jul; 52(1): 87-92. PMID: 9211350, ISSN: 0085-2538.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9211350.
  • Sakai M, Zhang M, Homma T, Garrick B, Abraham JA, McKanna JA, Harris RC. Production of heparin binding epidermal growth factor-like growth factor in the early phase of regeneration after acute renal injury. Isolation and localization of bioactive molecules. J. Clin. Invest. 1997 May 5/1/1997; 99(9): 2128-38. PMID: 9151785, PMCID: PMC508043, DOI: 10.1172/JCI119386, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9151785.
  • Harris RC. Growth factors and cytokines in acute renal failure. Adv Ren Replace Ther. 1997 Apr; 4(2 Suppl 1): 43-53. PMID: 9113240, ISSN: 1073-4449.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9113240.
  • Harris RC, Becker BN, Cheng HF. Acute and chronic mechanisms for regulating proximal tubule angiotensin II receptor expression. J. Am. Soc. Nephrol. 1997 Feb; 8(2): 306-13. PMID: 9048351, ISSN: 1046-6673.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9048351.
  • Becker BN, Harris RC. A potential mechanism for proximal tubule angiotensin II-mediated sodium flux associated with receptor-mediated endocytosis and arachidonic acid release. Kidney Int. Suppl. 1996 Dec; 57: S66-72. PMID: 8941925, ISSN: 0098-6577.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8941925.
  • Yasuda T, Kondo S, Homma T, Harris RC. Regulation of extracellular matrix by mechanical stress in rat glomerular mesangial cells. J. Clin. Invest. 1996 Nov 11/1/1996; 98(9): 1991-2000. PMID: 8903317, PMCID: PMC507642, DOI: 10.1172/JCI119003, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8903317.
  • Harris RC. The macula densa: recent developments. J. Hypertens. 1996 Jul; 14(7): 815-22. PMID: 8818919, ISSN: 0263-6352.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8818919.
  • Cheng HF, Becker BN, Harris RC. Dopamine decreases expression of type-1 angiotensin II receptors in renal proximal tubule. J. Clin. Invest. 1996 Jun 6/15/1996; 97(12): 2745-52. PMID: 8675685, PMCID: PMC507367, DOI: 10.1172/JCI118729, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8675685.
  • Harris RC, Cheng HF. The intrarenal renin-angiotensin system: a paracrine system for the local control of renal function separate from the systemic axis. Exp. Nephrol. 1996; 4 Suppl 1: 2-7. PMID: 9001891, ISSN: 1018-7782.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/9001891.
  • Becker BN, Cheng HF, Burns KD, Harris RC. Polarized rabbit type 1 angiotensin II receptors manifest differential rates of endocytosis and recycling. Am. J. Physiol. 1995 Oct; 269(4 Pt 1): C1048-56. PMID: 7485445, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7485445.
  • Burns KD, Capdevila J, Wei S, Breyer MD, Homma T, Harris RC. Role of cytochrome P-450 epoxygenase metabolites in EGF signaling in renal proximal tubule. Am. J. Physiol. 1995 Oct; 269(4 Pt 1): C831-40. PMID: 7485450, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7485450.
  • Homma T, Sakai M, Cheng HF, Yasuda T, Coffey RJ, Harris RC. Induction of heparin-binding epidermal growth factor-like growth factor mRNA in rat kidney after acute injury. J. Clin. Invest. 1995 Aug; 96(2): 1018-25. PMID: 7635938, PMCID: PMC185290, DOI: 10.1172/JCI118087, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7635938.
  • Cheng HF, Becker BN, Burns KD, Harris RC. Angiotensin II upregulates type-1 angiotensin II receptors in renal proximal tubule. J. Clin. Invest. 1995 May; 95(5): 2012-9. PMID: 7738168, PMCID: PMC295780, DOI: 10.1172/JCI117886, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7738168.
  • Harris RC, Martinez-Maldonado M. Angiotensin II-mediated renal injury. Miner Electrolyte Metab. 1995; 21(4-5): 328-35. PMID: 7565481, ISSN: 0378-0392.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7565481.
  • Threadgill, D.W., Dlugosz, A.A., Hansen, L., Tennenbaum, T., Lichi, U., Yee, D, LeMantia, C., Mourton, T., Herrup, K., Harris, RC, Barnard, J.A., Yuspa,S.H., Coffey, and Magnuson, T. Targeted disruption of mouse EGF-receptor: Evidence that genetic background affects mutant phenotype. Science. 1995; 269: 230-4.
  • Cheng HF, Burns KD, Harris RC. Reduced proximal tubule angiotensin II receptor expression in streptozotocin-induced diabetes mellitus. Kidney Int. 1994 Dec; 46(6): 1603-10. PMID: 7700017, ISSN: 0085-2538.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7700017.
  • Harris RC, McKanna JA, Akai Y, Jacobson HR, Dubois RN, Breyer MD. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J. Clin. Invest. 1994 Dec; 94(6): 2504-10. PMID: 7989609, PMCID: PMC330084, DOI: 10.1172/JCI117620, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7989609.
  • Akai Y, Homma T, Burns KD, Yasuda T, Badr KF, Harris RC. Mechanical stretch/relaxation of cultured rat mesangial cells induces protooncogenes and cyclooxygenase. Am. J. Physiol. 1994 Aug; 267(2 Pt 1): C482-90. PMID: 8074183, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8074183.
  • Harris RC, Ismail N. Extrarenal complications of the nephrotic syndrome. Am. J. Kidney Dis. 1994 Apr; 23(4): 477-97. PMID: 8154483, PII: S027263869400065X, ISSN: 0272-6386.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8154483.
  • Harris RC, Akai Y, Yasuda T, Homma T. Role of physical factors in the regulation of mesangial cell growth and the interaction with vasoactive agents. Exp. Nephrol. 1994 Mar; 2(2): 104. PMID: 8082000, ISSN: 1018-7782.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8082000.
  • Harris RC, Akai Y, Yasuda T, Homma T. The role of physical forces in alterations of mesangial cell function. Kidney Int. Suppl. 1994 Feb; 45: S17-21. PMID: 8158889, ISSN: 0098-6577.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8158889.
  • Harris, R.C., McKanna, J.A., Akai, Y., Jacobson, H.R., Dubois, R.N. and Breyer, M.D. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J. Clin. Invest. 1994; 94: 2504-10.
  • Burns KD, Inagami T, Harris RC. Cloning of a rabbit kidney cortex AT1 angiotensin II receptor that is present in proximal tubule epithelium. Am. J. Physiol. 1993 Apr; 264(4 Pt 2): F645-54. PMID: 7916579, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/7916579.
  • Homma T, Zhang JY, Shimizu T, Prakash C, Blair IA, Harris RC. Cyclooxygenase-derived metabolites of 8,9-epoxyeicosatrienoic acid are potent mitogens for cultured rat glomerular mesangial cells. Biochem. Biophys. Res. Commun. 1993 Feb 2/26/1993; 191(1): 282-8. PMID: 8447831, PII: S0006-291X(83)71214-3, DOI: 10.1006/bbrc.1993.1214, ISSN: 0006-291X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8447831.
  • Takahashi K, Harris RC, Capdevila JH, Karara A, Makita K, Jacobson HR, Munger KA, Badr KF. Induction of renal arachidonate cytochrome P-450 epoxygenase after uninephrectomy: counterregulation of hyperfiltration. J. Am. Soc. Nephrol. 1993 Feb; 3(8): 1496-500. PMID: 8387830, ISSN: 1046-6673.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8387830.
  • Burns KD, Homma T, Harris RC. The intrarenal renin-angiotensin system. Semin. Nephrol. 1993 Jan; 13(1): 13-30. PMID: 8434183, ISSN: 0270-9295.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8434183.
  • Harris RC, Burns KD, Alattar M, Homma T, Nakamura T. Hepatocyte growth factor stimulates phosphoinositide hydrolysis and mitogenesis in cultured renal epithelial cells. Life Sci. 1993; 52(13): 1091-100. PMID: 8383782, ISSN: 0024-3205.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/8383782.
  • McKanna JA, Chuncharunee A, Munger KA, Breyer JA, Cohen S, Harris RC. Localization of p35 (annexin I, lipocortin I) in normal adult rat kidney and during recovery from ischemia. J. Cell. Physiol. 1992 Dec; 153(3): 467-76. PMID: 1447309, DOI: 10.1002/jcp.1041530305, ISSN: 0021-9541.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1447309.
  • Homma T, Akai Y, Burns KD, Harris RC. Activation of S6 kinase by repeated cycles of stretching and relaxation in rat glomerular mesangial cells. Evidence for involvement of protein kinase C. J. Biol. Chem. 1992 Nov 11/15/1992; 267(32): 23129-35. PMID: 1429660, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1429660.
  • Harris RC, Haralson MA, Badr KF. Continuous stretch-relaxation in culture alters rat mesangial cell morphology, growth characteristics, and metabolic activity. Lab. Invest. 1992 May; 66(5): 548-54. PMID: 1573850, ISSN: 0023-6837.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1573850.
  • Harris, R.C. S6 kinase activity in proximal tubule cells. Evidence for activation by epidermal growth factor and angiotensin II in vitro and by contralateral nephrectomy in vivo. Am. J. Physiol. 1992; 263: F127-F134.
  • Homma T, Harris RC. Time-dependent biphasic regulation of Na+/K+/Cl- cotransport in rat glomerular mesangial cells. J. Biol. Chem. 1991 Jul 7/25/1991; 266(21): 13553-9. PMID: 1856192, ISSN: 0021-9258.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1856192.
  • Awazu M, Kon V, Harris RC, Imada T, Inagami T, Ichikawa I. Renal sympathetic nerves modulate glomerular ANP receptors and filtration. Am. J. Physiol. 1991 Jul; 261(1 Pt 2): F29-35. PMID: 1650144, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/1650144.
  • Harris RC. Potential physiologic roles for epidermal growth factor in the kidney. Am. J. Kidney Dis. 1991 Jun; 17(6): 627-30. PMID: 2042635, PII: S0272638691000987, ISSN: 0272-6386.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2042635.
  • Harris RC, Homma T, Jacobson HR, Capdevila J. Epoxyeicosatrienoic acids activate Na+/H+ exchange and are mitogenic in cultured rat glomerular mesangial cells. J. Cell. Physiol. 1990 Sep; 144(3): 429-37. PMID: 2167900, DOI: 10.1002/jcp.1041440310, ISSN: 0021-9541.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2167900.
  • Kon V, Harris RC, Ichikawa I. A regulatory role for large vessels in organ circulation. Endothelial cells of the main renal artery modulate intrarenal hemodynamics in the rat. J. Clin. Invest. 1990 Jun; 85(6): 1728-33. PMID: 2140836, PMCID: PMC296633, DOI: 10.1172/JCI114628, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2140836.
  • Harris RC, Munger KA, Badr KF, Takahashi K. Mediation of renal vascular effects of epidermal growth factor by arachidonate metabolites. FASEB J. 1990 Apr 4/1/1990; 4(6): 1654-60. PMID: 2138579, ISSN: 0892-6638.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2138579.
  • Harris RC, Badr KF. Recovery of prostaglandin synthesis in rat glomerular mesangial cells after aspirin inhibition: induction of cyclooxygenase activity by serum and epidermal growth factor. Prostaglandins. 1990 Feb; 39(2): 213-22. PMID: 2107566, ISSN: 0090-6980.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2107566.
  • Homma, T., Burns, K. and Harris R.C. Agonist stimulation of Na/K/Cl cotransport in cultured rat mesangial cells: Evidence for protein kinase C-dependent and calcium/calmodulin-dependent pathways. J. Biol. Chem. 1990; 265:: 17613-20.
  • Badr KF, Mong S, Hoover RL, Schwartzberg M, Ebert J, Jacobson HR, Harris RC. Leukotriene D4 binding and signal transduction in rat glomerular mesangial cells. Am. J. Physiol. 1989 Aug; 257(2 Pt 2): F280-7. PMID: 2548402, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2548402.
  • Harris RC, Daniel TO. Epidermal growth factor binding, stimulation of phosphorylation, and inhibition of gluconeogenesis in rat proximal tubule. J. Cell. Physiol. 1989 May; 139(2): 383-91. PMID: 2785525, DOI: 10.1002/jcp.1041390222, ISSN: 0021-9541.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2785525.
  • Badr KF, DeBoer DK, Takahashi K, Harris RC, Fogo A, Jacobson HR. Glomerular responses to platelet-activating factor in the rat: role of thromboxane A2. Am. J. Physiol. 1989 Jan; 256(1 Pt 2): F35-43. PMID: 2912165, ISSN: 0002-9513.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2912165.
  • Badr KF, Murray JJ, Breyer MD, Takahashi K, Inagami T, Harris RC. Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways. J. Clin. Invest. 1989 Jan; 83(1): 336-42. PMID: 2536045, PMCID: PMC303681, DOI: 10.1172/JCI113880, ISSN: 0021-9738.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/2536045.
  • Harris, R.C., Hoover, R.L., Jacobson, H.R. and Badr, K.F. Evidence for glomerular actions of epidermal growth factor in the rat. J. Clin Invest. 1988; 82: 1028-39.