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Reid M. Ness, M.D.

Assistant Professor of Medicine (Gastroenterology, Hepatology and Nutrition)

Contact Information:

Vanderbilt University Medical Center
6th Floor Medical Center East
Nashville, TN 37232-8300
615-322-0128
Fax: 615-343-8174

Education
  • M.P.H. - Indiana University, 1997
  • M.D. - Indiana University, 1990
  • Fellowship - Indiana University Medical Center, 1995
  • Residency - Duke University Health System, 1993
  • Internship - Duke University Health System, 1991
 
Publications
  • Zhao J, Zhu X, Shrubsole MJ, Ness RM, Hibler EA, Cai Q, Long J, Chen Z, Jiang M, Kabagambe EK, Zhang B, Hou L, Smalley WE, Edwards TL, Giovannucci EL, Zheng W, Dai Q. Interactions between calcium intake and polymorphisms in genes essential for calcium reabsorption and risk of colorectal neoplasia in a two-phase study. Mol. Carcinog [print-electronic]. 2017 Oct; 56(10): 2258-66. PMID: 28544176, PMCID: PMC5609815, DOI: 10.1002/mc.22678, ISSN: 1098-2744.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/28544176.
  • Sun P, Zhu X, Shrubsole MJ, Ness RM, Hibler EA, Cai Q, Long J, Chen Z, Li G, Hou L, Smalley WE, Edwards TL, Giovannucci E, Zheng W, Dai Q. Genetic variation in SLC7A2 interacts with calcium and magnesium intakes in modulating the risk of colorectal polyps. J. Nutr. Biochem [print-electronic]. 2017 Sep; 47: 35-40. PMID: 28501704, PMCID: PMC5583031, PII: S0955-2863(16)30708-2, DOI: 10.1016/j.jnutbio.2017.04.016, ISSN: 1873-4847.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/28501704.
  • Rifkin SB, Shrubsole MJ, Cai Q, Smalley WE, Ness RM, Swift LL, Zheng W, Murff HJ. PUFA levels in erythrocyte membrane phospholipids are differentially associated with colorectal adenoma risk. Br. J. Nutr [print-electronic]. 2017 Jun; 117(11): 1615-22. PMID: 28660850, PII: S0007114517001490, DOI: 10.1017/S0007114517001490, ISSN: 1475-2662.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/28660850.
  • Su T, Washington MK, Ness RM, Rex DK, Smalley WE, Ulbright TM, Cai Q, Zheng W, Shrubsole MJ. Comparison of biomarker expression between proximal and distal colorectal adenomas: The Tennessee-Indiana Adenoma Recurrence Study. Mol. Carcinog [print-electronic]. 2017 Feb; 56(2): 761-73. PMID: 27479195, PMCID: PMC5541935, DOI: 10.1002/mc.22533, ISSN: 1098-2744.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/27479195.
  • Davenport JR, Su T, Zhao Z, Coleman HG, Smalley WE, Ness RM, Zheng W, Shrubsole MJ. Modifiable lifestyle factors associated with risk of sessile serrated polyps, conventional adenomas and hyperplastic polyps. Gut [print-electronic]. 2016 Nov 11/15/2016; PMID: 27852795, PMCID: PMC5432410, PII: gutjnl-2016-312893, DOI: 10.1136/gutjnl-2016-312893, ISSN: 1468-3288.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/27852795.
  • Zhu X, Shrubsole MJ, Ness RM, Hibler EA, Cai Q, Long J, Chen Z, Li G, Jiang M, Hou L, Kabagambe EK, Zhang B, Smalley WE, Edwards TL, Giovannucci EL, Zheng W, Dai Q. Calcium/magnesium intake ratio, but not magnesium intake, interacts with genetic polymorphism in relation to colorectal neoplasia in a two-phase study. Mol. Carcinog [print-electronic]. 2016 Oct; 55(10): 1449-57. PMID: 26333203, PMCID: PMC4775445, DOI: 10.1002/mc.22387, ISSN: 1098-2744.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26333203.
  • Murff HJ, Tindle HA, Shrubsole MJ, Cai Q, Smalley W, Milne GL, Swift LL, Ness RM, Zheng W. Smoking and red blood cell phospholipid membrane fatty acids. Prostaglandins Leukot. Essent. Fatty Acids [print-electronic]. 2016 Sep; 112: 24-31. PMID: 27637337, PMCID: PMC5028119, PII: S0952-3278(16)30119-3, DOI: 10.1016/j.plefa.2016.08.004, ISSN: 1532-2823.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/27637337.
  • Davenport JR, Cai Q, Ness RM, Milne G, Zhao Z, Smalley WE, Zheng W, Shrubsole MJ. Evaluation of pro-inflammatory markers plasma C-reactive protein and urinary prostaglandin-E2 metabolite in colorectal adenoma risk. Mol. Carcinog [print-electronic]. 2016 Aug; 55(8): 1251-61. PMID: 26333108, PMCID: PMC4816675, DOI: 10.1002/mc.22367, ISSN: 1098-2744.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26333108.
  • Vaezi MF, Brill JV, Mills MR, Bernstein BB, Ness RM, Richards WO, Brillstein L, Leibowitz R, Strople K, Montgomery EA, Patel K. An Episode Payment Framework for Gastroesophageal Reflux Disease. Gastroenterology [print-electronic]. 2016 Apr; 150(4): 1019-25. PMID: 26907604, PII: S0016-5085(16)00228-6, DOI: 10.1053/j.gastro.2016.02.037, ISSN: 1528-0012.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26907604.
  • Vaezi MF, Brill JV, Mills MR, Bernstein BB, Ness RM, Richards WO, Brillstein L, Leibowitz R, Strople K, Montgomery EA, Patel K. An Episode Payment Framework for Gastroesophageal Reflux Disease: Symptomatic Gastroesophageal Reflux Disease, Dysplastic and Nondysplastic Barrett's Esophagus, and Anti-Reflux Surgical and Endoscopic Interventions. Gastroenterology [print-electronic]. 2016 Apr; 150(4): 1009-18. PMID: 26907603, PII: S0016-5085(16)00227-4, DOI: 10.1053/j.gastro.2016.02.036, ISSN: 1528-0012.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26907603.
  • Provenzale D, Jasperson K, Ahnen DJ, Aslanian H, Bray T, Cannon JA, David DS, Early DS, Erwin D, Ford JM, Giardiello FM, Gupta S, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Rao MS, Regenbogen SE, Shike M, Steinbach G, Weinberg D, Dwyer MA, Freedman-Cass DA, Darlow S, . Colorectal Cancer Screening, Version 1.2015. J Natl Compr Canc Netw. 2015 Aug; 13(8): 959-68; quiz 968. PMID: 26285241, PII: 13/8/959.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/26285241.
  • Shrubsole MJ, Wagner C, Zhu X, Hou L, Loukachevitch LV, Ness RM, Zheng W. Associations between S-adenosylmethionine, S-adenosylhomocysteine, and colorectal adenoma risk are modified by sex. Am J Cancer Res. 2015; 5(1): 458-65. PMID: 25628954, PMCID: PMC4300688, ISSN: 2156-6976.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25628954.
  • Zhu X, Liang J, Shrubsole MJ, Ness RM, Cai Q, Long J, Chen Z, Li G, Wiese D, Zhang B, Smalley WE, Edwards TL, Giovannucci E, Zheng W, Dai Q. Calcium intake and ion transporter genetic polymorphisms interact in human colorectal neoplasia risk in a 2-phase study. J. Nutr [print-electronic]. 2014 Nov; 144(11): 1734-41. PMID: 25165391, PMCID: PMC4195417, PII: jn.114.196709, DOI: 10.3945/jn.114.196709, ISSN: 1541-6100.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/25165391.
  • Fu Z, Shrubsole MJ, Smalley WE, Ness RM, Zheng W. Associations between dietary fiber and colorectal polyp risk differ by polyp type and smoking status. J. Nutr [print-electronic]. 2014 May; 144(5): 592-8. PMID: 24572038, PMCID: PMC4084407, PII: jn.113.183319, DOI: 10.3945/jn.113.183319, ISSN: 1541-6100.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/24572038.
  • Deng X, Song Y, Manson JE, Signorello LB, Zhang SM, Shrubsole MJ, Ness RM, Seidner DL, Dai Q. Magnesium, vitamin D status and mortality: results from US National Health and Nutrition Examination Survey (NHANES) 2001 to 2006 and NHANES III. BMC Med. 2013 Aug 8/27/2013; 11: 187. PMID: 23981518, PMCID: PMC3765911, PII: 1741-7015-11-187, DOI: 10.1186/1741-7015-11-187, ISSN: 1741-7015.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23981518.
  • Edwards TL, Shrubsole MJ, Cai Q, Li G, Dai Q, Rex DK, Ulbright TM, Fu Z, Delahanty RH, Murff HJ, Smalley W, Ness RM, Zheng W. Genome-wide association study identifies possible genetic risk factors for colorectal adenomas. Cancer Epidemiol. Biomarkers Prev [print-electronic]. 2013 Jul; 22(7): 1219-26. PMID: 23677573, PMCID: PMC3716448, PII: 1055-9965.EPI-12-1437, DOI: 10.1158/1055-9965.EPI-12-1437, ISSN: 1538-7755.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23677573.
  • Fu Z, Shrubsole MJ, Li G, Smalley WE, Hein DW, Cai Q, Ness RM, Zheng W. Interaction of cigarette smoking and carcinogen-metabolizing polymorphisms in the risk of colorectal polyps. Carcinogenesis [print-electronic]. 2013 Apr; 34(4): 779-86. PMID: 23299405, PMCID: PMC3616674, PII: bgs410, DOI: 10.1093/carcin/bgs410, ISSN: 1460-2180.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23299405.
  • Zhang B, Shrubsole MJ, Li G, Cai Q, Edwards T, Smalley WE, Ness RM, Zheng W. Association of genetic variants for colorectal cancer differs by subtypes of polyps in the colorectum. Carcinogenesis [print-electronic]. 2012 Dec; 33(12): 2417-23. PMID: 23027627, PMCID: PMC3510743, PII: bgs308, DOI: 10.1093/carcin/bgs308, ISSN: 1460-2180.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23027627.
  • Fu Z, Shrubsole MJ, Smalley WE, Wu H, Chen Z, Shyr Y, Ness RM, Zheng W. Lifestyle factors and their combined impact on the risk of colorectal polyps. Am. J. Epidemiol [print-electronic]. 2012 Nov 11/1/2012; 176(9): 766-76. PMID: 23079606, PMCID: PMC3571253, PII: kws157, DOI: 10.1093/aje/kws157, ISSN: 1476-6256.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23079606.
  • Fu Z, Shrubsole MJ, Li G, Smalley WE, Hein DW, Chen Z, Shyr Y, Cai Q, Ness RM, Zheng W. Using gene-environment interaction analyses to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps. Am. J. Clin. Nutr [print-electronic]. 2012 Nov; 96(5): 1119-28. PMID: 23015320, PMCID: PMC3471199, PII: ajcn.112.040345, DOI: 10.3945/ajcn.112.040345, ISSN: 1938-3207.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/23015320.
  • Murff HJ, Shrubsole MJ, Cai Q, Smalley WE, Dai Q, Milne GL, Ness RM, Zheng W. Dietary intake of PUFAs and colorectal polyp risk. Am. J. Clin. Nutr [print-electronic]. 2012 Mar; 95(3): 703-12. PMID: 22277551, PMCID: PMC3278245, PII: ajcn.111.024000, DOI: 10.3945/ajcn.111.024000, ISSN: 1938-3207.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22277551.
  • Shrubsole MJ, Cai Q, Wen W, Milne G, Smalley WE, Chen Z, Ness RM, Zheng W. Urinary prostaglandin E2 metabolite and risk for colorectal adenoma. Cancer Prev Res (Phila) [print-electronic]. 2012 Feb; 5(2): 336-42. PMID: 22166248, PMCID: PMC3273609, PII: 1940-6207.CAPR-11-0426, DOI: 10.1158/1940-6207.CAPR-11-0426, ISSN: 1940-6215.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/22166248.
  • Murff HJ, Shrubsole MJ, Chen Z, Smalley WE, Chen H, Shyr Y, Ness RM, Zheng W. Nonsteroidal anti-inflammatory drug use and risk of adenomatous and hyperplastic polyps. Cancer Prev Res (Phila) [print-electronic]. 2011 Nov; 4(11): 1799-807. PMID: 21764857, PMCID: PMC3203989, PII: 1940-6207.CAPR-11-0107, DOI: 10.1158/1940-6207.CAPR-11-0107, ISSN: 1940-6215.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21764857.
  • Fu Z, Shrubsole MJ, Smalley WE, Wu H, Chen Z, Shyr Y, Ness RM, Zheng W. Association of meat intake and meat-derived mutagen exposure with the risk of colorectal polyps by histologic type. Cancer Prev Res (Phila) [print-electronic]. 2011 Oct; 4(10): 1686-97. PMID: 21803984, PMCID: PMC3188364, PII: 1940-6207.CAPR-11-0191, DOI: 10.1158/1940-6207.CAPR-11-0191, ISSN: 1940-6215.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/21803984.
  • Pritchett JM, Aslam M, Slaughter JC, Ness RM, Garrett CG, Vaezi MF. Efficacy of esophageal impedance/pH monitoring in patients with refractory gastroesophageal reflux disease, on and off therapy. Clin. Gastroenterol. Hepatol [print-electronic]. 2009 Jul; 7(7): 743-8. PMID: 19281866, PII: S1542-3565(09)00199-2, DOI: 10.1016/j.cgh.2009.02.022, ISSN: 1542-7714.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19281866.
  • Wu H, Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Smalley WE, Chen H, Li M, Shyr Y, Zheng W. Fruit and vegetable intakes are associated with lower risk of colorectal adenomas. J. Nutr [print-electronic]. 2009 Feb; 139(2): 340-4. PMID: 19091801, PMCID: PMC2646202, PII: jn.108.098889, DOI: 10.3945/jn.108.098889, ISSN: 1541-6100.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/19091801.
  • Shrubsole MJ, Wu H, Ness RM, Shyr Y, Smalley WE, Zheng W. Alcohol drinking, cigarette smoking, and risk of colorectal adenomatous and hyperplastic polyps. Am. J. Epidemiol [print-electronic]. 2008 May 5/1/2008; 167(9): 1050-8. PMID: 18304959, PII: kwm400, DOI: 10.1093/aje/kwm400, ISSN: 1476-6256.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18304959.
  • Shin A, Shrubsole MJ, Rice JM, Cai Q, Doll MA, Long J, Smalley WE, Shyr Y, Sinha R, Ness RM, Hein DW, Zheng W. Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk. Cancer Epidemiol. Biomarkers Prev. 2008 Feb; 17(2): 320-9. PMID: 18268115, PMCID: PMC2572782, PII: 17/2/320, DOI: 10.1158/1055-9965.EPI-07-0615, ISSN: 1055-9965.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/18268115.
  • Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Cai Q, Smalley WE, Li M, Shyr Y, Zheng W. The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. Am. J. Clin. Nutr. 2007 Sep; 86(3): 743-51. PMID: 17823441, PMCID: PMC2082111, PII: 86/3/743, ISSN: 0002-9165.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17823441.
  • Shin A, Shrubsole MJ, Ness RM, Wu H, Sinha R, Smalley WE, Shyr Y, Zheng W. Meat and meat-mutagen intake, doneness preference and the risk of colorectal polyps: the Tennessee Colorectal Polyp Study. Int. J. Cancer. 2007 Jul 7/1/2007; 121(1): 136-42. PMID: 17354224, DOI: 10.1002/ijc.22664, ISSN: 0020-7136.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17354224.
  • Peterson NB, Murff HJ, Ness RM, Dittus RS. Colorectal cancer screening among men and women in the United States. J Womens Health (Larchmt). 2007 Jan; 16(1): 57-65. PMID: 17324097, DOI: 10.1089/jwh.2006.0131, ISSN: 1540-9996.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17324097.
  • Murff HJ, Shrubsole MJ, Smalley WE, Wu H, Shyr Y, Ness RM, Zheng W. The interaction of age and hormone replacement therapy on colon adenoma risk. Cancer Detect. Prev [print-electronic]. 2007; 31(2): 161-5. PMID: 17433566, PMCID: PMC1949417, PII: S0361-090X(07)00034-7, DOI: 10.1016/j.cdp.2007.03.002, ISSN: 0361-090X.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/17433566.
  • Johnson JC, Schmidt CR, Shrubsole MJ, Billheimer DD, Joshi PR, Morrow JD, Heslin MJ, Washington MK, Ness RM, Zheng W, Schwartz DA, Coffey RJ, Beauchamp RD, Merchant NB. Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. Clin. Gastroenterol. Hepatol [print-electronic]. 2006 Nov; 4(11): 1358-65. PMID: 16996805, PII: S1542-3565(06)00772-5, DOI: 10.1016/j.cgh.2006.07.015, ISSN: 1542-3565.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16996805.
  • Fowke JH, Morrow JD, Motley S, Bostick RM, Ness RM. Brassica vegetable consumption reduces urinary F2-isoprostane levels independent of micronutrient intake. Carcinogenesis [print-electronic]. 2006 Oct; 27(10): 2096-102. PMID: 16704986, PII: bgl065, DOI: 10.1093/carcin/bgl065, ISSN: 0143-3334.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16704986.
  • Su Y, Shrubsole MJ, Ness RM, Cai Q, Kataoka N, Washington K, Zheng W. Immunohistochemical expressions of Ki-67, cyclin D1, beta-catenin, cyclooxygenase-2, and epidermal growth factor receptor in human colorectal adenoma: a validation study of tissue microarrays. Cancer Epidemiol. Biomarkers Prev. 2006 Sep; 15(9): 1719-26. PMID: 16985035, PII: 15/9/1719, DOI: 10.1158/1055-9965.EPI-05-0946, ISSN: 1055-9965.
    Available from: http://www.ncbi.nlm.nih.gov/pubmed/16985035.