Vanderbilt-Ingram Cancer Center

Publications

• Wright, S, Parham, C, Lee, B, Clarke, D, Auckland, L, Johnston, J, Lawrence, AL, Dickeson, SK, Santoro, SA, Griswold-Prenner, I, Bix, G Perlecan domain V inhibits α2 integrin-mediated amyloid-β neurotoxicity. Neurobiol Aging, 2010.
• Zou, Z, Schmaier, AA, Cheng, L, Mericko, P, Dickeson, SK, Stricker, TP, Santoro, SA, Kahn, ML Negative regulation of activated alpha-2 integrins during thrombopoiesis. Blood, 113(25), 6428-39, 2009.
• Marjoram, RJ, Voss, B, Pan, Y, Dickeson, SK, Zutter, MM, Hamm, HE, Santoro, SA Suboptimal activation of protease-activated receptors enhances alpha2beta1 integrin-mediated platelet adhesion to collagen. J Biol Chem, 284(50), 34640-7, 2009.
• Santoro, SA, Mosse, CA, Young, PP The MD/PhD pathway to a career in laboratory medicine. Clin Lab Med, 27(2), 425-34; abstract ix, 2007.
• Grenache, DG, Zhang, Z, Wells, LE, Santoro, SA, Davidson, JM, Zutter, MM Wound healing in the alpha2beta1 integrin-deficient mouse: altered keratinocyte biology and dysregulated matrix metalloproteinase expression. J Invest Dermatol, 127(2), 455-66, 2007.
• Maginnis, MS, Forrest, JC, Kopecky-Bromberg, SA, Dickeson, SK, Santoro, SA, Zutter, MM, Nemerow, GR, Bergelson, JM, Dermody, TS Beta1 integrin mediates internalization of mammalian reovirus. J Virol, 80(6), 2760-70, 2006.
• Edelson, BT, Stricker, TP, Li, Z, Dickeson, SK, Shepherd, VL, Santoro, SA, Zutter, MM Novel collectin/C1q receptor mediates mast cell activation and innate immunity. Blood, 107(1), 143-50, 2006.
• Sarratt, KL, Chen, H, Zutter, MM, Santoro, SA, Hammer, DA, Kahn, ML GPVI and alpha2beta1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow. Blood, 106(4), 1268-77, 2005.
• Bix, G, Fu, J, Gonzalez, EM, Macro, L, Barker, A, Campbell, S, Zutter, MM, Santoro, SA, Kim, JK, Höök, M, Reed, CC, Iozzo, RV Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. J Cell Biol, 166(1), 97-109, 2004.
• Wang, Hui, Fu, Weili, Im, Jae Hong, Zhou, Zengyi, Santoro, Samuel A., Iyer, Vandana, DiPersio, C. Mike, Yu, Qian-Chun, Quaranta, Vito, Al-Mehdi, Abu, Muschel, Ruth J. Tumor cell {alpha}3{beta}1 integrin and vascular laminin-5 mediate pulmonary arrest and metastasis. J Cell Biol, 164(6), 935-941, 2004.
• Grenache, David G, Coleman, Trey, Semenkovich, Clay F, Santoro, Samuel A, Zutter, Mary M Alpha2beta1 integrin and development of atherosclerosis in a mouse model: assessment of risk. Arterioscler Thromb Vasc Biol, 23(11), 2104-9, 2003.
• He, Li, Pappan, Loretta K, Grenache, David G, Li, Zhengzhi, Tollefsen, Douglas M, Santoro, Samuel A, Zutter, Mary M The contributions of the {alpha}2{beta}1 integrin to vascular thrombosis in vivo. Blood, 102(), 3652-3657, 2003.
• Chen, Jianchun, Diacovo, Thomas G, Grenache, David G, Santoro, Samuel A, Zutter, Mary M The alpha(2) integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis. Am J Pathol, 161337-44, 2002.
• Ohman, T, King, S L, Krithivas, A, Cunningham, J, Dickeson, S K, Santoro, S A, Bergelson, J M Echoviruses 1 and 8 are closely related genetically, and bind to similar determinants within the VLA-2 I domain. Virus Res, 761-8, 2001.
• Klekotka, P A, Santoro, S A, Ho, A, Dowdy, S F, Zutter, M M Mammary epithelial cell-cycle progression via the alpha(2)beta(1) integrin: unique and synergistic roles of the alpha(2) cytoplasmic domain. Am J Pathol, 159983-92, 2001.
• Dumin, J A, Dickeson, S K, Stricker, T P, Bhattacharyya-Pakrasi, M, Roby, J D, Santoro, S A, Parks, W C Pro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen. J Biol Chem, 27629368-74, 2001.
• Klekotka, P A, Santoro, S A, Wang, H, Zutter, M M Specific residues within the alpha 2 integrin subunit cytoplasmic domain regulate migration and cell cycle progression via distinct MAPK pathways. J Biol Chem, 27632353-61, 2001.
• Stricker, T P, Dumin, J A, Dickeson, S K, Chung, L, Nagase, H, Parks, W C, Santoro, S A Structural analysis of the alpha(2) integrin I domain/procollagenase-1 (matrix metalloproteinase-1) interaction. J Biol Chem, 27629375-81, 2001.
• Klekotka, P A, Santoro, S A, Zutter, M M alpha 2 integrin subunit cytoplasmic domain-dependent cellular migration requires p38 MAPK. J Biol Chem, 2769503-11, 2001.
• Keene, D R, San Antonio, J D, Mayne, R, McQuillan, D J, Sarris, G, Santoro, S A, Iozzo, R V Decorin binds near the C terminus of type I collagen. J Biol Chem, 27521801-4, 2000.
• Ding, Q, Gladson, C L, Guidry, C R, Santoro, S A, Dickeson, S K, Shin, J T, Thompson, J A Extracellular FGF-1 inhibits cytoskeletal organization and promotes fibroblast motility. Growth Factors, 1893-107, 2000.
• Wang, H, Gai, Q, Yang, X, Li, Z, Linders, B, Santoro, S A, Zutter, M M Role of the alpha1 and alpha2 integrin cytoplasmic domains in cell morphology, motility and responsiveness to stimulation by the protein kinase C pathway. Cell Adhes Commun, 7281-97, 2000.
• Zutter, M M, Santoro, S A, Wu, J E, Wakatsuki, T, Dickeson, S K, Elson, E L Collagen receptor control of epithelial morphogenesis and cell cycle progression. Am J Pathol, 155927-40, 1999.
• Dickeson, S K, Mathis, N L, Rahman, M, Bergelson, J M, Santoro, S A Determinants of ligand binding specificity of the alpha(1)beta(1) and alpha(2)beta(1) integrins. J Biol Chem, 27432182-91, 1999.
• Hamerski, D A, Santoro, S A, Integrins and the kidney: biology and pathobiology.. Curr Opin Nephrol Hypertens, 89-14, 1999.
• Santoro, S A Platelet surface collagen receptor polymorphisms: variable receptor expression and thrombotic/hemorrhagic risk. Blood, 933575-7, 1999.
• Xu, J, Zutter, M M, Santoro, S A, Clark, R A A three-dimensional collagen lattice activates NF-kappaB in human fibroblasts: role in integrin alpha2 gene expression and tissue remodeling. J Cell Biol, 140(3), 709-19, 1998.
• Bhattacharyya-Pakrasi, M, Dickeson, S K, Santoro, S A, Alpha2beta1 integrin recognition of the carboxyl-terminal propeptide of type I procollagen: integrin recognition and feed-back regulation of matrix biosynthesis are mediated by distinct sequences.. Matrix Biol, 17223-32, 1998.
• Zutter, M M, Sun, H, Santoro, S A Altered integrin expression and the malignant phenotype: the contribution of multiple integrated integrin receptors. J Mammary Gland Biol Neoplasia, 3191-200, 1998.
• Dickeson, S K, Walsh, J J, Santoro, S A, Binding of the alpha 2 integrin I domain to extracellular matrix ligands: structural and mechanistic differences between collagen and laminin binding.. Cell Adhes Commun, 5273-81, 1998.
• Sun, H, Santoro, S A, Zutter, M M Downstream events in mammary gland morphogenesis mediated by reexpression of the alpha2beta1 integrin: the role of the alpha6 and beta4 integrin subunits. Cancer Res, 58(10), 2224-33, 1998.
• Dickeson, S K, Bhattacharyya-Pakrasi, M, Mathis, N L, Schlesinger, P H, Santoro, S A Ligand binding results in divalent cation displacement from the alpha 2 beta 1 integrin I domain: evidence from terbium luminescence spectroscopy. Biochemistry, 37(32), 11280-8, 1998.
• Dickeson, S K, Santoro, S A Ligand recognition by the I domain-containing integrins. Cell Mol Life Sci, 54(6), 556-66, 1998.
• Zutter, M M, Santoro, S A The ups and downs of alpha 2 beta 1-integrin expression: contributions to epithelial cell differentiation and the malignant phenotype. Curr Top Microbiol Immunol, 231167-85, 1998.
• Dickeson, S K, Walsh, J J, Santoro, S A Contributions of the I and EF hand domains to the divalent cation-dependent collagen binding activity of the alpha2beta1 integrin. J Biol Chem, 272(12), 7661-8, 1997.
• Dieckgraefe, B K, Weems, D M, Santoro, S A, Alpers, D H ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction. Biochem Biophys Res Commun, 233(2), 389-94, 1997.
• Windus, D W, Santoro, S A, Atkinson, R, Royal, H D Effects of antiplatelet drugs on dialysis-associated platelet deposition in polytetrafluoroethylene grafts. Am J Kidney Dis, 29(4), 560-4, 1997.
• Despotis, G J, Ikonomakou, S, Levine, V, Joiner-Maier, D, Santoro, S A, Joist, J H Effects of platelets and white blood cells and antiplatelet agent C7E3 (Reopro) on a new test of PAF procoagulant activity of whole blood. Thromb Res, 86(3), 205-19, 1997.
• Despotis, G J, Levine, V, Joist, H, Santoro, S A, Mendeloff, E Multiple episodes of thrombosis with biventricular support devices with inadequate anticoagulation and evidence of accelerated intravascular coagulation. J Thorac Cardiovasc Surg, 113(2), 419-22, 1997.
• Staatz, W D, Walsh, J J, Santoro, S A The alpha 2 beta 1 integrin binds to the CB4 peptide of the alpha 2(I) collagen chain. Biochem Mol Biol Int, 42(3), 577-82, 1997.
• Despotis, G J, Joist, J H, Goodnough, L T, Santoro, S A, Spitznagel, E Whole blood heparin concentration measurements by automated protamine titration agree with plasma anti-Xa measurements. J Thorac Cardiovasc Surg, 113(3), 611-3, 1997.
• Wu, J E, Santoro, S A Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn, 206(2), 169-81, 1996.
• Despotis, G J, Levine, V, Filos, K S, Santoro, S A, Joist, J H, Spitznagel, E, Goodnough, L T Evaluation of a new point-of-care test that measures PAF-mediated acceleration of coagulation in cardiac surgical patients. Anesthesiology, 85(6), 1311-23, 1996.
• Despotis, G J, Alsoufiev, A, Hogue, C W, Zoys, T N, Goodnough, L T, Santoro, S A, Kater, K M, Barnes, P, Lappas, D G Evaluation of complete blood count results from a new, on-site hemocytometer compared with a laboratory-based hemocytometer. Crit Care Med, 24(7), 1163-7, 1996.
• Dieckgraefe, B K, Santoro, S A, Alpers, D H Immunolocalization of alpha-integrin subunits and extracellular matrix components during human colonic organogenesis. Gastroenterology, 110(1), 58-71, 1996.
• Despotis, G J, Joist, J H, Hogue, C W, Alsoufiev, A, Joiner-Maier, D, Santoro, S A, Spitznagel, E, Weitz, J I, Goodnough, L T More effective suppression of hemostatic system activation in patients undergoing cardiac surgery by heparin dosing based on heparin blood concentrations rather than ACT. Thromb Haemost, 76(6), 902-8, 1996.
• Xu, J, Zutter, M M, Santoro, S A, Clark, R A PDGF induction of alpha 2 integrin gene expression is mediated by protein kinase C-zeta. J Cell Biol, 134(5), 1301-11, 1996.
• Windus, DW, Atkinson, R, Santoro, S The effects of hemodialysis on platelet activation with new and reprocessed regenerated cellulose dialyzers. Am J Kidney Dis, 27(3), 387-93, 1996.
• Keely, P J, Fong, A M, Zutter, M M, Santoro, S A Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense alpha 2 integrin mRNA in mammary cells. J Cell Sci, 108 ( Pt 2)595-607, 1995.
• Despotis, G J, Joist, J H, Joiner-Maier, D, Alsoufiev, A L, Triantafillou, A N, Goodnough, L T, Santoro, S A, Lappas, D G Effect of aprotinin on activated clotting time, whole blood and plasma heparin measurements. Ann Thorac Surg, 59(1), 106-11, 1995.
• Despotis, G J, Hogue, C W, Santoro, S A, Joist, J H, Barnes, P W, Lappas, D G Effect of heparin on whole blood activated partial thromboplastin time using a portable, whole blood coagulation monitor. Crit Care Med, 23(10), 1674-9, 1995.
• Saelman, E U, Keely, P J, Santoro, S A Loss of MDCK cell alpha 2 beta 1 integrin expression results in reduced cyst formation, failure of hepatocyte growth factor/scatter factor-induced branching morphogenesis, and increased apoptosis. J Cell Sci, 108 ( Pt 11)3531-40, 1995.
• Zutter, M M, Santoro, S A, Staatz, W D, Tsung, Y L Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells. Proc Natl Acad Sci U S A, 92(16), 7411-5, 1995.
• Santoro, S A, Zutter, M M The alpha 2 beta 1 integrin: a collagen receptor on platelets and other cells. Thromb Haemost, 74(3), 813-21, 1995.
• Windus, DW, Santoro, S, Royal, HD The effects of hemodialysis on platelet deposition in prosthetic graft fistulas. Am J Kidney Dis, 26(4), 614-21, 1995.
• Despotis, G J, Joist, J H, Hogue, C W, Alsoufiev, A, Kater, K, Goodnough, L T, Santoro, S A, Spitznagel, E, Rosenblum, M, Lappas, D G The impact of heparin concentration and activated clotting time monitoring on blood conservation. A prospective, randomized evaluation in patients undergoing cardiac operation. J Thorac Cardiovasc Surg, 110(1), 46-54, 1995.
• Keely, P J, Wu, J E, Santoro, S A The spatial and temporal expression of the alpha 2 beta 1 integrin and its ligands, collagen I, collagen IV, and laminin, suggest important roles in mouse mammary morphogenesis. Differentiation, 59(1), 1-13, 1995.
• Santoro, S A, Zutter, M M, Wu, J E, Staatz, W D, Saelman, E U, Keely, P J Analysis of collagen receptors. Methods Enzymol, 245147-83, 1994.
• Santoro, S A Antiphospholipid antibodies and thrombotic predisposition: underlying pathogenetic mechanisms. Blood, 83(9), 2389-91, 1994.
• Despotis, G J, Summerfield, A L, Joist, J H, Goodnough, L T, Santoro, S A, Spitznagel, E, Cox, J L, Lappas, D G Comparison of activated coagulation time and whole blood heparin measurements with laboratory plasma anti-Xa heparin concentration in patients having cardiac operations. J Thorac Cardiovasc Surg, 108(6), 1076-82, 1994.
• Wu, J E, Santoro, S A Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. Dev Dyn, 199(4), 292-314, 1994.
• Despotis, G J, Summerfield, A L, Joist, J H, Goodnough, L T, Santoro, S A, Zimmermann, J J, Lappas, D G In vitro reversal of heparin effect with heparinase: evaluation with whole blood prothrombin time and activated partial thromboplastin time in cardiac surgical patients. Anesth Analg, 79(4), 670-4, 1994.
• Choi, ET, Engel, L, Callow, AD, Sun, S, Trachtenberg, J, Santoro, S, Ryan, US Inhibition of neointimal hyperplasia by blocking alpha V beta 3 integrin with a small peptide antagonist GpenGRGDSPCA. J Vasc Surg, 19(1), 125-34, 1994.
• Despotis, G J, Santoro, S A, Spitznagel, E, Kater, K M, Barnes, P, Cox, J L, Lappas, D G On-site prothrombin time, activated partial thromboplastin time, and platelet count. A comparison between whole blood and laboratory assays with coagulation factor analysis in patients presenting for cardiac surgery. Anesthesiology, 80(2), 338-51, 1994.
• Despotis, G J, Santoro, S A, Spitznagel, E, Kater, K M, Cox, J L, Barnes, P, Lappas, D G Prospective evaluation and clinical utility of on-site monitoring of coagulation in patients undergoing cardiac operation. J Thorac Cardiovasc Surg, 107(1), 271-9, 1994.
• Zutter, M M, Santoro, S A, Painter, A S, Tsung, Y L, Gafford, A The human alpha 2 integrin gene promoter. Identification of positive and negative regulatory elements important for cell-type and developmentally restricted gene expression. J Biol Chem, 269(1), 463-9, 1994.
• Fong, A M, Santoro, S A Transcriptional regulation of alpha IIb integrin gene expression during megakaryocytic differentiation of K562 cells. Role of a silencer element. J Biol Chem, 269(28), 18441-7, 1994.
• Zutter, M M, Krigman, H R, Santoro, S A Altered integrin expression in adenocarcinoma of the breast. Analysis by in situ hybridization. Am J Pathol, 142(5), 1439-48, 1993.
• Winters, K J, Walsh, J J, Rubin, B G, Santoro, S A Platelet interactions with fibronectin: divalent cation-independent platelet adhesion to the gelatin-binding domain of fibronectin. Blood, 81(7), 1778-86, 1993.
• Rubin, B G, Santoro, S A, Sicard, G A Platelet interactions with the vessel wall and prosthetic grafts. Ann Vasc Surg, 7(2), 200-7, 1993.
• Pacifici, R, Basilico, C, Roman, J, Zutter, M M, Santoro, S A, McCracken, R Collagen-induced release of interleukin 1 from human blood mononuclear cells. Potentiation by fibronectin binding to the alpha 5 beta 1 integrin. J Clin Invest, 89(1), 61-7, 1992.
• Zutter, M M, Fong, A M, Krigman, H R, Santoro, S A Differential regulation of the alpha 2 beta 1 and alpha IIb beta 3 integrin genes during megakaryocytic differentiation of pluripotential K562 cells. J Biol Chem, 267(28), 20233-8, 1992.
• Burger, S R, Zutter, M M, Sturgill-Koszycki, S, Santoro, S A Induced cell surface expression of functional alpha 2 beta 1 integrin during megakaryocytic differentiation of K562 leukemic cells. Exp Cell Res, 202(1), 28-35, 1992.
• Rubin, B G, McGraw, D J, Sicard, G A, Santoro, S A New RGD analogue inhibits human platelet adhesion and aggregation and eliminates platelet deposition on canine vascular grafts. J Vasc Surg, 15(4), 683-91; discussion 691-2, 1992.
• Hortin, G L, Staatz, W D, Santoro, S A Preparation of soluble peptide libraries: application to studies of platelet adhesion sequences. Biochem Int, 26(4), 731-8, 1992.
• Pacifici, R, Carano, A, Santoro, S A, Rifas, L, Jeffrey, J J, Malone, J D, McCracken, R, Avioli, L V Bone matrix constituents stimulate interleukin-1 release from human blood mononuclear cells. J Clin Invest, 87(1), 221-8, 1991.
• Santoro, S A, Walsh, J J, Staatz, W D, Baranski, K J Distinct determinants on collagen support alpha 2 beta 1 integrin-mediated platelet adhesion and platelet activation. Cell Regul, 2(11), 905-13, 1991.
• Staatz, W D, Fok, K F, Zutter, M M, Adams, S P, Rodriguez, B A, Santoro, S A Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen. J Biol Chem, 266(12), 7363-7, 1991.
• Winters, K J, Santoro, S A, Miletich, J P, Eisenberg, P R Relative importance of thrombin compared with plasmin-mediated platelet activation in response to plasminogen activation with streptokinase. Circulation, 84(4), 1552-60, 1991.
• Love, P E, Santoro, S A Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Prevalence and clinical significance. Ann Intern Med, 112(9), 682-98, 1990.
• Zutter, M M, Mazoujian, G, Santoro, S A Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast. Am J Pathol, 137(4), 863-70, 1990.
• Winters, K J, Eisenberg, P R, Jaffe, A S, Santoro, S A Dependence of plasmin-mediated degradation of platelet adhesive receptors on temperature and Ca2+. Blood, 76(8), 1546-57, 1990.
• Staatz, W D, Peters, K J, Santoro, S A Divalent cation-dependent structure in the platelet membrane glycoprotein Ia-IIa (VLA-2) complex. Biochem Biophys Res Commun, 168(1), 107-14, 1990.
• Staatz, W D, Walsh, J J, Pexton, T, Santoro, S A The alpha 2 beta 1 integrin cell surface collagen receptor binds to the alpha 1 (I)-CB3 peptide of collagen. J Biol Chem, 265(9), 4778-81, 1990.
• Torr, S R, Winters, K J, Santoro, S A, Sobel, B E The nature of interactions between tissue-type plasminogen activator and platelets. Thromb Res, 59(2), 279-93, 1990.
• Zutter, M M, Santoro, S A Widespread histologic distribution of the alpha 2 beta 1 integrin cell-surface collagen receptor. Am J Pathol, 137(1), 113-20, 1990.
• Hawrylowicz, C M, Santoro, S A, Platt, F M, Unanue, E R Activated platelets express IL-1 activity. J Immunol, 143(12), 4015-8, 1989.
• Santoro, S A Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by complex gangliosides. Blood, 73(2), 484-9, 1989.
• McGoff, M A, Allen, B T, Der, T, Sicard, G A, Santoro, S A Mechanisms of vascular graft thrombosis: role of altered canine platelet sensitivity to thromboxane. Thromb Res, 55(6), 695-707, 1989.
• Santoro, S A, Lawing, W J Modulation of an RGDS binding site on the platelet membrane glycoprotein IIb-IIIa complex. Biochem Biophys Res Commun, 160(1), 189-95, 1989.
• Staatz, W D, Rajpara, S M, Wayner, E A, Carter, W G, Santoro, S A The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen. J Cell Biol, 108(5), 1917-24, 1989.
• Hortin, G L, Tollefsen, D M, Santoro, S A Assessment of interference by heparin cofactor II in the DuPont aca antithrombin-III assay. Am J Clin Pathol, 89(4), 515-7, 1988.
• Bourey, R E, Santoro, S A Interactions of exercise, coagulation, platelets, and fibrinolysis--a brief review. Med Sci Sports Exerc, 20(5), 439-46, 1988.
• Santoro, S A, Rajpara, S M, Staatz, W D, Woods, V L Isolation and characterization of a platelet surface collagen binding complex related to VLA-2. Biochem Biophys Res Commun, 153(1), 217-23, 1988.
• Santoro, S A Molecular basis of platelet adhesion to collagen. Prog Clin Biol Res, 283291-314, 1988.
• Santoro, S A, Lawing, W J Competition for related but nonidentical binding sites on the glycoprotein IIb-IIIa complex by peptides derived from platelet adhesive proteins. Cell, 48(5), 867-73, 1987.
• Santoro, S A, Frazier, W A Isolation and characterization of thrombospondin. Methods Enzymol, 144438-46, 1987.
• Santoro, S A The dualistic mechanisms of platelet adhesion to von Willebrand factor substrates. Exp Cell Res, 173(2), 413-24, 1987.
• Santoro, S A Thrombospondin and the adhesive behavior of platelets. Semin Thromb Hemost, 13(3), 290-7, 1987.
• Santoro, S A Identification of a 160,000 dalton platelet membrane protein that mediates the initial divalent cation-dependent adhesion of platelets to collagen. Cell, 46(6), 913-20, 1986.
• Santoro, S A, Cowan, J F Thrombin enhanced adhesion of platelets to von Willebrand factor substrates. Thromb Res, 43(1), 57-72, 1986.
• Dixit, V M, Haverstick, D M, O''Rourke, K M, Hennessy, S W, Grant, G A, Santoro, S A, Frazier, W A A monoclonal antibody against human thrombospondin inhibits platelet aggregation. Proc Natl Acad Sci U S A, 82(10), 3472-6, 1985.
• Haverstick, D M, Dixit, V M, Grant, G A, Frazier, W A, Santoro, S A Characterization of the platelet agglutinating activity of thrombospondin. Biochemistry, 24(13), 3128-34, 1985.
• Cornelison, G S, Rollins, A, Santoro, S A Duplicate coagulation assays warranted. Am J Clin Pathol, 84(2), 261-2, 1985.
• Dixit, V M, Haverstick, D M, O''Rourke, K M, Hennessy, S W, Grant, G A, Santoro, S A, Frazier, W A Effects of anti-thrombospondin monoclonal antibodies on the agglutination of erythrocytes and fixed, activated platelets by purified thrombospondin. Biochemistry, 24(16), 4270-5, 1985.
• Haverstick, D M, Cowan, J F, Yamada, K M, Santoro, S A Inhibition of platelet adhesion to fibronectin, fibrinogen, and von Willebrand factor substrates by a synthetic tetrapeptide derived from the cell-binding domain of fibronectin. Blood, 66(4), 946-52, 1985.
• Dixit, V M, Haverstick, D M, O''Rourke, K, Hennessy, S W, Broekelmann, T J, McDonald, J A, Grant, G A, Santoro, S A, Frazier, W A Inhibition of platelet aggregation by a monoclonal antibody against human fibronectin. Proc Natl Acad Sci U S A, 82(11), 3844-8, 1985.
• Galvin, N J, Dixit, V M, O''Rourke, K M, Santoro, S A, Grant, G A, Frazier, W A Mapping of epitopes for monoclonal antibodies against human platelet thrombospondin with electron microscopy and high sensitivity amino acid sequencing. J Cell Biol, 101(4), 1434-41, 1985.
• Roberts, D D, Haverstick, D M, Dixit, V M, Frazier, W A, Santoro, S A, Ginsburg, V The platelet glycoprotein thrombospondin binds specifically to sulfated glycolipids. J Biol Chem, 260(16), 9405-11, 1985.
• Dixit, V M, Grant, G A, Santoro, S A, Frazier, W A Isolation and characterization of a heparin-binding domain from the amino terminus of platelet thrombospondin. J Biol Chem, 259(16), 10100-5, 1984.
• Dixit, V M, Grant, G A, Frazier, W A, Santoro, S A Isolation of the fibrinogen-binding region of platelet thrombospondin. Biochem Biophys Res Commun, 119(3), 1075-81, 1984.
• Haverstick, D M, Dixit, V M, Grant, G A, Frazier, W A, Santoro, S A Localization of the hemagglutinating activity of platelet thrombospondin to a 140 000-dalton thermolytic fragment. Biochemistry, 23(23), 5597-603, 1984.
• Santoro, S A, Cowan, J F Mechanism of inhibition by trinitrophenylation of the ristocetin cofactor activity of von Willebrand factor. Biochim Biophys Acta, 797(2), 178-85, 1984.
• Shafer, K E, Santoro, S A, Sobel, B E, Jaffe, A S Monitoring activity of fibrinolytic agents. A therapeutic challenge. Am J Med, 76(5), 879-86, 1984.
• Santoro, S A Differential effects of concanavalin A and succinyl concanavalin A on the macromolecular events of platelet activation. Biochim Biophys Acta, 757(1), 101-10, 1983.
• Santoro, S A Inhibition of platelet aggregation by fibronectin. Biochem Biophys Res Commun, 116(1), 135-40, 1983.
• Santoro, S A Preferential binding of high molecular weight forms of von Willebrand factor to fibrillar collagen. Biochim Biophys Acta, 756(1), 123-6, 1983.
• Santoro, S A, Cowan, J F Adsorption of von Willebrand factor by fibrillar collagen--implications concerning the adhesion of platelets to collagen. Coll Relat Res, 2(1), 31-43, 1982.
• Santoro, S A Amino group modification inhibits ristocetin cofactor activity of human von Willebrand factor. Biochem Biophys Res Commun, 108(2), 479-85, 1982.
• Santoro, S A, Cunningham, L W Platelet-collagen adhesion. Methods Enzymol, 82 Pt A509-13, 1982.
• Santoro, S A Adsorption of von Willebrand factor/factor VIII by the genetically distinct interstitial collagens. Thromb Res, 21(6), 689-91, 1981.
• Santoro, S A, Cunningham, L W Platelet-collagen adhesion-membrane fluidity and the development of high affinity adhesion through multiple interacting sites. Coll Relat Res, 1(6), 517-26, 1981.
• Santoro, S A, Cunningham, L W Collagen-mediated platelet aggregation: the role of multiple interactions between the platelet surface and collagen. Thromb Haemost, 43(2), 158-62, 1980.
• Santoro, S A, Cunningham, L W Fibronectin and the multiple interaction model for platelet-collagen adhesion. Proc Natl Acad Sci U S A, 76(6), 2644-8, 1979.
• Cunningham, LW, Santoro, S, Davies, H Primary hemostasis (collagen-platelet interaction): introduction. Suppl Thromb Haemost, 63205-13, 1978.
• Santoro, S A, Cunningham, L W Collagen-mediated platelet aggregation. Evidence for multivalent interactions of intermediate specificity between collagen and platelets. J Clin Invest, 60(5), 1054-60, 1977.