Vanderbilt-Ingram Cancer Center

Publications

• Zhuang, G, Brantley-Sieders, DM, Vaught, D, Yu, J, Xie, L, Wells, S, Jackson, D, Muraoka-Cook, R, Arteaga, C, Chen, J Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy. Cancer Res, 70(1), 299-308, 2010.
• Chopra, SS, Stroud, DM, Watanabe, H, Bennett, JS, Burns, CG, Wells, KS, Yang, T, Zhong, TP, Roden, DM Voltage-gated sodium channels are required for heart development in zebrafish. Circ Res, 106(8), 1342-50, 2010.
• Martin, MD, Fingleton, B, Lynch, CC, Wells, S, McIntyre, JO, Piston, DW, Matrisian, LM Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth. Clin Exp Metastasis, 25(8), 877-85, 2008.
• Nyman, LR, Wells, KS, Head, WS, McCaughey, M, Ford, E, Brissova, M, Piston, DW, Powers, AC Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets. J Clin Invest, 118(11), 3790-7, 2008.
• Jia, H, King, IN, Chopra, SS, Wan, H, Ni, TT, Jiang, C, Guan, X, Wells, S, Srivastava, D, Zhong, TP Vertebrate heart growth is regulated by functional antagonism between Gridlock and Gata5. Proc Natl Acad Sci U S A, 104(35), 14008-13, 2007.
• Hallaq, H, Yang, Z, Viswanathan, PC, Fukuda, K, Shen, W, Wang, DW, Wells, KS, Zhou, J, Yi, J, Murray, KT Quantitation of protein kinase A-mediated trafficking of cardiac sodium channels in living cells. Cardiovasc Res, 72(2), 250-61, 2006.
• Xu, M, Wells, KS, Emeson, RB Substrate-dependent contribution of double-stranded RNA-binding motifs to ADAR2 function. Mol Biol Cell, 17(7), 3211-20, 2006.
• Bundy, L, Wells, S, Sealy, L C/EBPbeta-2 confers EGF-independent growth and disrupts the normal acinar architecture of human mammary epithelial cells. Mol Cancer, 443, 2005.
• Boczko, EM, Cooper, TG, Gedeon, T, Mischaikow, K, Murdock, DG, Pratap, S, Wells, KS Structure theorems and the dynamics of nitrogen catabolite repression in yeast. Proc Natl Acad Sci U S A, 102(16), 5647-52, 2005.
• Kanki, H, Kupershmidt, S, Yang, T, Wells, S, Roden, DM A structural requirement for processing the cardiac K+ channel KCNQ1. J Biol Chem, 279(32), 33976-83, 2004.
• McIntyre, J Oliver, Fingleton, Barbara, Wells, K Sam, Piston, David W, Lynch, Conor C, Gautam, Shiva, Matrisian, Lynn M Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity. Biochem J, 377(Pt 3), 617-28, 2004.
• Manza LL, Codreanu SG, Stamer SL, Smith DL, Wells KS, Roberts RL, Liebler DC "Global Shifts in Protein Sumoylation in Response to Electrophile and Oxidative Stress." Chem Res Toxicol, 17(12), 1706-1715, 2004.
• Sheng, J, Organ, EL, Hao, C, Wells, KS, Ruley, HE, Rubin, DH Mutations in the IGF-II pathway that confer resistance to lytic reovirus infection. BMC Cell Biol, 5(1), 32, 2004.
• Campbell, M, Qu, S, Wells, S, Sugandha, H, Jensen, RA An adenoviral vector containing an arg-gly-asp (RGD) motif in the fiber knob enhances protein product levels from transgenes refractory to expression. Cancer Gene Ther, 10(7), 559-70, 2003.
• Sansam, Christopher L, Wells, K Sam, Emeson, Ronald B Modulation of RNA editing by functional nucleolar sequestration of ADAR2. Proc Natl Acad Sci U S A, 100(24), 14018-23, 2003.
• Kupershmidt, Sabina, Yang, Iris C-H, Sutherland, Margaret, Wells, K Sam, Yang, Tao, Yang, Ping, Balser, Jeffrey R, Roden, Dan M Cardiac-enriched LIM domain protein fhl2 is required to generate I(Ks) in a heterologous system. Cardiovasc Res, 5693-103, 2002.
• Gurrieri, S, Wells, K S, Johnson, I D, Bustamante, C Direct visualization of individual DNA molecules by fluorescence microscopy: characterization of the factors affecting signal/background and optimization of imaging conditions using YOYO. Anal Biochem, 24944-53, 1997.
• Poot, M, Zhang, Y Z, Kramer, J A, Wells, K S, Jones, L J, Hanzel, D K, Lugade, A G, Singer, V L, Haugland, R P Analysis of mitochondrial morphology and function with novel fixable fluorescent stains. J Histochem Cytochem, 441363-72, 1996.
• Gurrieri, S, Smith, S B, Wells, K S, Johnson, I D, Bustamante, C Real-time imaging of the reorientation mechanisms of YOYO-labelled DNA molecules during 90 degrees and 120 degrees pulsed field gel electrophoresis. Nucleic Acids Res, 244759-67, 1996.
• Larison, K D, BreMiller, R, Wells, K S, Clements, I, Haugland, R P Use of a new fluorogenic phosphatase substrate in immunohistochemical applications. J Histochem Cytochem, 4377-83, 1995.
• Singer, V L, Paragas, V B, Larison, K D, Wells, K S, Fox, C J, Haugland, R P, Fluorescence-based signal amplification technology.. Am Biotechnol Lab, 1255-58, 1994.
• Wells, K.S. and Johnson, I.D. "Fluorescent Labels for Confocal Microscopy." In: Three Dimensional Confocal Microscopy: Volume Investigation of Biological Specimens, Stevens, J., Mills, L.R. and Trogadis, J., Eds,(Acadedmic Press), 101-129, 1994.
• Sandison, D.R., Williams, R.M., Wells, K.S., Strickler, J. and Webb, W.W. "Quantitative Fluorescence Confocal Laser Scanning Microscopy (CLSM)." In: Handbook of Confocal Microscopy, 2nd Edition, (Pawley, J., Ed.), Plenum, 1994.
• Haugland, R P, You, W, Paragas, V B, Wells, K S, DuBose, D A, Simultaneous visualization of G- and F-actin in endothelial cells.. J Histochem Cytochem, 42345-50, 1994.
• Kwon,Y.H., Wells, K.S. and Hoch, H.C. "Fluorescence Confocal Microscopy: Applications in Fungal Cytology." Mycologia, 85721-733, 1993.
• Webb, W.W., Wells, K.S., Sandison, D.R. and Strickler, J. "Criteria for Quantitative Dynamical Confocal Fluorescence Imaging." In: An International Conference on Digitized Video Microscopy, Alan R. Liss, Inc., 1990.
• Wells, K.S., Sandison, D.R., Strickler, J. and Webb, W.W. "Quantitative Fluorescence Imaging in Laser Scanning Confocal Microscopy." In: Handbook of Biological Confocal Microscopy, Pawley, J. Ed.Plenum, 1990.
• Spada,G.P., Gotterelli, G., Samori, B., Bustamante, C.J. and Wells, K.S. "A Study of some Lyotropic Cholesteric Mesophases by Circular and Linear Dichroism and by Circular Intensity Differential Scattering." Liquid Crystals 3, 1101-113, 1988.
• Beach, D A, Bustamante, C, Wells, K S, Foucar, K M, Differential polarization imaging. III. Theory confirmation. Patterns of polymerization of hemoglobin S in red blood sickle cells.. Biophys J, 53449-56, 1988.
• Garab,G., Wells, S. Finzi, C.and Bustamante, C. "Helically Organized Macroaggregates of Pigment Protein Complexes in Chloroplasts: Evidence from Circular Intensity Differential Scattering." Biochemistry, 275839-5843, 1988.
• Beach, D.A., Wells, K.S., Husher, F. and Bustamante, C. "Differential Polarization Microscope Using an Image Dissector Camera and Phase Lock Detection." Rev. Sci. Instr., 581987-1995, 1987.
• Beach, D A, Bustamante, C, Wells, K S, Foucar, K M, Differential polarization imaging. III. Theory confirmation. Patterns of polymerization of hemoglobin S in red blood sickle cells.. Biophys J, 52947-54, 1987.
• Wells, K S, Beach, D A, Keller, D, Bustamante, C An analysis of circular intensity differential scattering measurements: studies on the sperm cell of Eledone cirrhosa. Biopolymers, 25(11), 2043-64, 1986.
• Bustamante, C, Maestre, M F, Wells, K S Recent advances in polarization spectroscopy: perspectives of the extension to the soft X-ray region. Photochem Photobiol, 44(3), 331-41, 1986.
• Hall, K., Wells, K.S., Keller, D., Samori, B., Maestre, M.F., Tinoco, Jr.I. and Bustamante, C. "Circular Intensity Differential Scattering of Planar and Focal Conic Orientations of Cholesteric Liquid Crystals." In: Applications of Circularly Polarized Radiation, Allen, F.S. and Bustamante, C., Eds.Plenum, 1985.
• Bustamante, C., Wells, K.S., Keller, D., Samori, B., Maestre, M.F. and Tinoco, I.,Jr "Circular Intensity Differential Scattering of Cholesteric and Blue Mesophases." Mol. Cryst. and Liq. Cryst., 11179-102, 1984.
• Katz, J.E., Wells, K.S., Ussery, D., Maestre, M.F. and Bustamante, C. "Design and Construction of a Circular Intensity Differential Scattering Instrument." Rev. Sci. Instr., 551574-1579, 1984.