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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center

 
Sudhansu K.  Dey

Sudhansu K. Dey, Ph.D.

Professor
Researcher

Contact Information:

Vanderbilt University Medical Center
D-4100 Medical Center North
Nashville, TN 37232-2678
615-322-8642

Research Specialty

defining the molecular and genetic basis of preimplantation embryo development and embryo-uterine interactions during blastocyst implantation

Research Description

Dey's laboratory has been engaged for more than three decades in defining the molecular and genetic basis of preimplantation embryo development and embryo-uterine interactions during blastocyst implantation. His group has addressed critical roles of growth factors, regulatory molecules, cytokines, and lipid mediators in the uterus and embryo during early pregnancy. The work from Dey's laboratory has been published in numerous peer-reviewed journals including Nature, Science, Cell, PNAS, Genes & Development, Development, Developmental Biology, JBC, JCI and Molecular Endocrinology. His ongoing research is to elucidate critical role of ligand-receptor signaling with endocannabinoids, roles cPLA2-COX-2 derived prostaglandins, PPARs, LIF, Hoxa-10 and roles of developmental genes in implantation and pregnancy establishment. His group is also engaged in studying global gene and protein expression profiles in the uterus and embryo during implantation by employing genomics and proteomics approaches.

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Clinical Research Description

Studies on the roles of oncogenes and cyclooxygenase-derived prostaglandins in the initiation and progression of uterine and ovarian cancers.

Publications