The VICC.ORG Directory of Doctors, Healthcare Providers & Researchers
Zhongming Zhao, Ph.D.
See also:
Director, Bioinformatics Resource Center
Associate Professor of Biomedical Informatics
Associate Professor of Psychiatry
Associate Professor of Cancer Biology
VICC Member
Researcher
Contact Information:
Vanderbilt University Medical Center
2525 West End Avenue, Suite 600
Nashville, TN 37203
615-343-9158
Research Specialty
Bioinformatics and Systems Biology, Personalized Medicine, Translational Bioinformatics, Cancer Biology, Neuropsychiatric Genetics
Research Description
The research interest of the Bioinformatics and Systems Biology Laboratory (BSBL, http://bioinfo.mc.vanderbilt.edu/) focus on the application of bioinformatics and systems biology approaches to studying complex diseases such as cancer and schizophrenia, aiming to uncover their molecular mechanisms that are otherwise undetected by classical approaches. The ongoing projects use data generated from high throughput technologies such as next generation sequencing and microarrays. Integrative genomics approaches are often applied.
Publications
- Jia, P, Wang, L, Fanous, AH, Chen, X, Kendler, KS, , , Zhao, Z A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia. J Med Genet, 49(2), 96-103, 2012.
- Wang Q, Xia J, Jia P, Pao W, Zhao Z "Application of next generation sequencing to human gene fusion detection: computational tools, features and perspectives." Briefings in Bioinformatics, in press, 2012.
- Dahlman, KB, Xia, J, Hutchinson, K, Ng, C, Hucks, D, Jia, P, Atefi, M, Su, Z, Branch, S, Lyle, P, Hicks, DJ, Bozon, V, Glaspy, JA, Rosen, N, Solit, DB, Netterville, JL, Vnencak-Jones, CL, Sosman, JA, Ribas, A, Zhao, Z, Pao, W BRAF L597 mutations in melanoma are associated with sensitivity to MEK inhibitors. Cancer Discov, 2012.
- Ahmed, ST, Davulcu, H, Tikves, S, Nair, R, Zhao, Z BioEve Search: A Novel Framework to Facilitate Interactive Literature Search. Adv Bioinformatics, 2012509126, 2012.
- Flynn, C, Zheng, S, Yan, L, Hedges, L, Womack, B, Fessel, J, Cogan, J, Austin, E, Loyd, J, West, J, Zhao, Z, Hamid, R Connectivity Map Analysis of Nonsense-Mediated Decay-Positive BMPR2-Related Hereditary Pulmonary Arterial Hypertension Provides Insights into Disease Penetrance. Am J Respir Cell Mol Biol, 47(1), 20-7, 2012.
- Jia, P, Li, F, Xia, J, Chen, H, Ji, H, Pao, W, Zhao, Z Consensus rules in variant detection from next-generation sequencing data. PLoS One, 7(6), e38470, 2012.
- Zheng, S, Zhao, Z DNA methylation profiling distinguishes three clusters of breast cancer cell lines. Chem Biodivers, 9(5), 848-56, 2012.
- Sun J, Wu Y, Xu H, Zhao Z DTome: a web-based tool for drug-target interactome construction. BMC Bioinformatics, 13S7, 2012.
- Kao, CF, Jia, P, Zhao, Z, Kuo, PH Enriched pathways for major depressive disorder identified from a genome-wide association study. Int J Neuropsychopharmacol, 1-11, 2012.
- Du, X, Han, L, Guo, AY, Zhao, Z Features of methylation and gene expression in the promoter-associated CpG islands using human methylome data. Comp Funct Genomics, 2012598987, 2012.
- Zheng, S, Zhao, Z GenRev: exploring functional relevance of genes in molecular networks. Genomics, 99(3), 183-8, 2012.
- Fanous, AH, Middleton, FA, Gentile, K, Amdur, RL, Maher, BS, Zhao, Z, Sun, J, Medeiros, H, Carvalho, C, Ferreira, SR, Macedo, A, Knowles, JA, Azevedo, MH, Pato, MT, Pato, CN Genetic overlap of schizophrenia and bipolar disorder in a high-density linkage survey in the Portuguese Island population. Am J Med Genet B Neuropsychiatr Genet, 159B(4), 383-91, 2012.
- Liu, Y, Koyutürk, M, Maxwell, S, Zhao, Z, Chance, MR Integrative analysis of common neurodegenerative diseases using gene association, interaction networks and mRNA expression data. AMIA Summits Transl Sci Proc, 201262-71, 2012.
- Sun, J, Jayathilake, K, Zhao, Z, Meltzer, HY Investigating association of four gene regions (GABRB3, MAOB, PAH, and SLC6A4) with five symptoms in schizophrenia. Psychiatry Res, 2012.
- Coburn, LA, Gong, X, Singh, K, Asim, M, Scull, BP, Allaman, MM, Williams, CS, Rosen, MJ, Washington, MK, Barry, DP, Piazuelo, MB, Casero, RA, Chaturvedi, R, Zhao, Z, Wilson, KT L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis. PLoS One, 7(3), e33546, 2012.
- Liu, M, Wu, Y, Chen, Y, Sun, J, Zhao, Z, Chen, XW, Matheny, ME, Xu, H Large-scale prediction of adverse drug reactions using chemical, biological, and phenotypic properties of drugs. J Am Med Inform Assoc, 19(e1), e28-e35, 2012.
- Webb, BT, Guo, AY, Maher, BS, Zhao, Z, van den Oord, EJ, Kendler, KS, Riley, BP, Gillespie, NA, Prescott, CA, Middeldorp, CM, Willemsen, G, de Geus, EJ, Hottenga, JJ, Boomsma, DI, Slagboom, EP, Wray, NR, Montgomery, GW, Martin, NG, Wright, MJ, Heath, AC, Madden, PA, Gelernter, J, Knowles, JA, Hamilton, SP, Weissman, MM, Fyer, AJ, Huezo-Diaz, P, McGuffin, P, Farmer, A, Craig, IW, Lewis, C, Sham, P, Crowe, RR, Flint, J, Hettema, JM Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes. Eur J Hum Genet, 2012.
- Xia, J, Wang, Q, Jia, P, Wang, B, Pao, W, Zhao, Z NGS catalog: A database of next generation sequencing studies in humans. Hum Mutat, 33(6), E2341-55, 2012.
- Jia, P, Wang, L, Fanous, AH, Pato, CN, Edwards, TL, , , Zhao, Z Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia. PLoS Comput Biol, 8(7), e1002587, 2012.
- Sun, J, Xu, H, Zhao, Z Network-assisted investigation of antipsychotic drugs and their targets. Chem Biodivers, 9(5), 900-10, 2012.
- Jia, P, Zhao, Z Personalized pathway enrichment map of putative cancer genes from next generation sequencing data. PLoS One, 7(5), e37595, 2012.
- Wu, Y, Liu, M, Zheng, WJ, Zhao, Z, Xu, H Ranking gene-drug relationships in biomedical literature using latent dirichlet allocation. Pac Symp Biocomput, 422-33, 2012.
- Garcia, CB, Shaffer, CM, Alfaro, MP, Smith, AL, Sun, J, Zhao, Z, Young, PP, VanSaun, MN, Eid, JE Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2. Oncogene, 31(18), 2323-34, 2012.
- Sun, Y, Zheng, S, Torossian, A, Speirs, CK, Schleicher, S, Giacalone, NJ, Carbone, DP, Zhao, Z, Lu, B Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells. Int J Radiat Oncol Biol Phys, 82(3), e563-72, 2012.
- Zhao, Z, Kier, LB, Buck, GA Systems biology: molecular networks and disease. Chem Biodivers, 9(5), 841-7, 2012.
- Sun, J, Gong, X, Purow, B, Zhao, Z Uncovering MicroRNA and Transcription Factor Mediated Regulatory Networks in Glioblastoma. PLoS Comput Biol, 8(7), e1002488, 2012.
- Jia, P, Kao, CF, Kuo, PH, Zhao, Z A comprehensive network and pathway analysis of candidate genes in major depressive disorder. BMC Syst Biol, 5 Suppl 3S12, 2011.
- Jia P, Kao CF, Kuo PH, Zhao Z A comprehensive network and pathway analysis of candidate genes in major depressive disorder. BMC Systems Biology , 5S12, 2011.
- Wang, L, Jia, P, Wolfinger, RD, Chen, X, Grayson, BL, Aune, TM, Zhao, Z An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies. Bioinformatics, 2011.
- Sun, J, Wan, C, Jia, P, Fanous, AH, Kendler, KS, Riley, BP, Zhao, Z Application of systems biology approach identifies and validates GRB2 as a risk gene for schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample. Schizophr Res, 125(2-3), 201-8, 2011.
- Jia, P, Tian, J, Zhao, Z Assessing gene length biases in gene set analysis of Genome-Wide Association Studies. Int J Comput Biol Drug Des, 3(4), 297-310, 2011.
- Bigdeli, TB, Maher, BS, Zhao, Z, Oord, EJ, Thiselton, DL, Sun, J, Webb, BT, Amdur, RL, Wormley, B, O''Neill, FA, Walsh, D, Riley, BP, Kendler, KS, Fanous, AH Comprehensive gene-based association study of a chromosome 20 linked region implicates novel risk loci for depressive symptoms in psychotic illness. PLoS One, 6(12), e21440, 2011.
- Su, Z, Han, L, Zhao, Z Conservation and divergence of DNA methylation in eukaryotes: New insights from single base-resolution DNA methylomes. Epigenetics, 6(2), 2011.
- Putnam, DK, Sun, J, Zhao, Z Exploring schizophrenia drug-gene interactions through molecular network and pathway modeling. AMIA Annu Symp Proc, 20111127-33, 2011.
- Su, Z, Xia, J, Zhao, Z Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome. BMC Genomics, 12 Suppl 5S15, 2011.
- Beeghly-Fadiel, A, Shu, XO, Lu, W, Long, J, Cai, Q, Xiang, YB, Zheng, Y, Zhao, Z, Gu, K, Gao, YT, Zheng, W Genetic variation in VEGF family genes and breast cancer risk: a report from the Shanghai Breast Cancer Genetics Study. Cancer Epidemiol Biomarkers Prev, 20(1), 33-41, 2011.
- Adkins DE, Aberg K, McClay JL, Bukszar J, Zhao Z, Jia P, Stroup ST, Perkins D, McEvoy JP, Lieberman JA, Sullivan PF, van den Oord E Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs. Molecular Psychiatry, 16 (3), 321-332, 2011.
- Gordy, LE, Bezbradica, JS, Flyak, AI, Spencer, CT, Dunkle, A, Sun, J, Stanic, AK, Boothby, MR, He, YW, Zhao, Z, Van Kaer, L, Joyce, S IL-15 regulates homeostasis and terminal maturation of NKT cells. J Immunol, 187(12), 6335-45, 2011.
- Zheng, S, Tansey, WP, Hiebert, SW, Zhao, Z Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma. BMC Med Genomics, 462, 2011.
- Zhao, Z, Xia, J, Tastan, O, Singh, I, Kshirsagar, M, Carbonell, J, Klein-Seetharaman, J Virus interactions with human signal transduction pathways. Int J Comput Biol Drug Des, 4(1), 83-105, 2011.
- Jia, P, Zheng, S, Long, J, Zheng, W, Zhao, Z dmGWAS: dense module searching for genome-wide association studies in protein-protein interaction networks. Bioinformatics, 27(1), 95-102, 2011.
- Sun, J, Zhao, Z A comparative study of cancer proteins in the human protein-protein interaction network. BMC Genomics, 11 Suppl 3S5, 2010.
- Zhang, M, Zhao, Z, He, L, Wan, C A meta-analysis of oxidative stress markers in schizophrenia. Sci China Life Sci, 53(1), 112-24, 2010.
- Guo, AY, Sun, J, Jia, P, Zhao, Z A novel microRNA and transcription factor mediated regulatory network in schizophrenia. BMC Syst Biol, 410, 2010.
- Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J, Edenberg H, Kramer J, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BR A systematic gene-based screen of Chr4q22-q32 identifies associate of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts. Hum Mol Genet, 19(12), 2497-2506, 2010.
- Jia, P, Wang, L, Meltzer, HY, Zhao, Z Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data. Schizophr Res, 122(1-3), 38-42, 2010.
- Huang, HC, Zheng, S, VanBuren, V, Zhao, Z Discovering disease-specific biomarker genes for cancer diagnosis and prognosis. Technol Cancer Res Treat, 9(3), 219-30, 2010.
- Zhao, Z, Jiang, C Features of recent codon evolution: a comparative polymorphism-fixation study. J Biomed Biotechnol, 2010202918, 2010.
- Sun, J, Zhao, Z Functional features, biological pathways, and protein interaction networks of addiction-related genes. Chem Biodivers, 7(5), 1153-62, 2010.
- Bhaskara, S, Knutson, SK, Jiang, G, Chandrasekharan, MB, Wilson, AJ, Zheng, S, Yenamandra, A, Locke, K, Yuan, JL, Bonine-Summers, AR, Wells, CE, Kaiser, JF, Washington, MK, Zhao, Z, Wagner, FF, Sun, ZW, Xia, F, Holson, EB, Khabele, D, Hiebert, SW Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell, 18(5), 436-47, 2010.
- Archer, KJ, Zhao, Z, Guennel, T, Maluf, DG, Fisher, RA, Mas, VR Identifying genes progressively silenced in preneoplastic and neoplastic liver tissues. Int J Comput Biol Drug Des, 3(1), 52-67, 2010.
- Guo, AY, Sun, J, Jia, P, Zhao, Z Network analysis of EtOH-related candidate genes. Chem Biodivers, 7(5), 1142-52, 2010.
- Jia, P, Wang, L, Meltzer, HY, Zhao, Z Pathway-based analysis of GWAS datasets: effective but caution required. Int J Neuropsychopharmacol, 1-6, 2010.
- Jia, P, Sun, J, Guo, AY, Zhao, Z SZGR: a comprehensive schizophrenia gene resource. Mol Psychiatry, 15(5), 453-62, 2010.
- Sun, J, Jia, P, Fanous, AH, van den Oord, E, Chen, X, Riley, BP, Amdur, RL, Kendler, KS, Zhao, Z Schizophrenia gene networks and pathways and their applications for novel candidate gene selection. PLoS One, 5(6), e11351, 2010.
- Zhao, Z, Kier, LB, Buck, GA Systems biology in the microbial world and beyond. Chem Biodivers, 7(5), 1019-25, 2010.
- Chmielecki, J, Peifer, M, Jia, P, Socci, ND, Hutchinson, K, Viale, A, Zhao, Z, Thomas, RK, Pao, W Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer. Nucleic Acids Res, 38(20), 6985-96, 2010.
- Sun, J, Jia, P, Fanous, AH, Webb, BT, van den Oord, EJ, Chen, X, Bukszar, J, Kendler, KS, Zhao, Z A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases-schizophrenia as a case. Bioinformatics, 25(19), 2595-6602, 2009.
- Chen, X, Sun, C, Chen, Q, O''Neill, FA, Walsh, D, Fanous, AH, Chowdari, KV, Nimgaonkar, VL, Scott, A, Schwab, SG, Wildenauer, DB, Che, R, Tang, W, Shi, Y, He, L, Luo, XJ, Su, B, Edwards, TL, Zhao, Z, Kendler, KS Apoptotic engulfment pathway and schizophrenia. PLoS One, 4(9), e6875, 2009.
- Han, L, Zhao, Z Contrast features of CpG islands in the promoter and other regions in the dog genome. Genomics, 94(2), 117-24, 2009.
- Han, L, Zhao, Z CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome. BMC Bioinformatics, 1065, 2009.
- Zhao, Z, Han, L CpG islands: algorithms and applications in methylation studies. Biochem Biophys Res Commun, 382(4), 643-5, 2009.
- Guo, AY, Webb, BT, Miles, MF, Zimmerman, MP, Kendler, KS, Zhao, Z ERGR: An ethanol-related gene resource. Nucleic Acids Res, 37(Database issue), D840-5, 2009.
- Clarke, RA, Zhao, Z, Guo, AY, Roper, K, Teng, L, Fang, ZM, Samaratunga, H, Lavin, MF, Gardiner, RA New genomic structure for prostate cancer specific gene PCA3 within BMCC1: implications for prostate cancer detection and progression. PLoS One, 4(3), e4995, 2009.
- Zhao Z, Khan F, Borker M, Herrera R, Agrawal S Presence of three different paternal lineages among North Indians: A study of 560 Y chromosomes. Annals Hum Biol, 36(1), 46-59, 2009.
- Riley, B, Kuo, PH, Maher, BS, Fanous, AH, Sun, J, Wormley, B, O''Neill, FA, Walsh, D, Zhao, Z, Kendler, KS The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample. Schizophr Res, 2009.
- Guo, AY, Sun, J, Riley, BP, Thiselton, DL, Kendler, KS, Zhao, Z The dystrobrevin-binding protein 1 gene: features and networks. Mol Psychiatry, 14(1), 18-29, 2009.
- Luo, XJ, Diao, HB, Wang, JK, Zhang, H, Zhao, ZM, Su, B Association of haplotypes spanning PDZ-GEF2, LOC728637 and ACSL6 with schizophrenia in Han Chinese. J Med Genet, 45(12), 818-26, 2008.
- Sun, J, Kuo, PH, Riley, BP, Kendler, KS, Zhao, Z Candidate genes for schizophrenia: a survey of association studies and gene ranking. Am J Med Genet B Neuropsychiatr Genet, 147B(7), 1173-81, 2008.
- Han, L, Zhao, Z Comparative analysis of CpG islands in four fish genomes. Comp Funct Genomics, 565631, 2008.
- Yu, QB, Li, G, Wang, G, Sun, JC, Wang, PC, Wang, C, Mi, HL, Ma, WM, Cui, J, Cui, YL, Chong, K, Li, YX, Li, YH, Zhao, Z, Shi, TL, Yang, ZN Construction of a chloroplast protein interaction network and functional mining of photosynthetic proteins in Arabidopsis thaliana. Cell Res, 18(10), 1007-19, 2008.
- Han, L, Su, B, Li, WH, Zhao, Z CpG island density and its correlations with genomic features in mammalian genomes. Genome Biol, 9(5), R79, 2008.
- Sun, J, Han, L, Zhao, Z Gene- and evidence-based candidate gene selection for schizophrenia and gene feature analysis. Artif Intell Med, 48(2-3), 99-106, 2008.
- Tassabehji, M, Fang, ZM, Hilton, EN, McGaughran, J, Zhao, Z, de Bock, CE, Howard, E, Malass, M, Donnai, D, Diwan, A, Manson, FD, Murrell, D, Clarke, RA Mutations in GDF6 are associated with vertebral segmentation defects in Klippel-Feil syndrome. Hum Mutat, 29(8), 1017-27, 2008.
- Zhao, Z, Khan, F, Borkar, M, Herrera, R, Agrawal, S Presence of three different paternal lineages among North Indians: a study of 560 Y chromosomes. Ann Hum Biol, 36(1), 46-59, 2008.
- Sun, J, Zhao, Z Construction of phylogenetic profiles based on the genetic distance of hundreds of genomes. Biochem Biophys Res Commun, 355(3), 849-53, 2007.
- Jiang, C, Han, L, Su, B, Li, WH, Zhao, Z Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes. Mol Biol Evol, 24(9), 1991-2000, 2007.
- Sun, J, Sun, Y, Ding, G, Liu, Q, Wang, C, He, Y, Shi, T, Li, Y, Zhao, Z InPrePPI: an integrated evaluation method based on genomic context for predicting protein-protein interactions in prokaryotic genomes. BMC Bioinformatics, 8414, 2007.
- Zhao, Z, Jiang, C Methylation-dependent transition rates are dependent on local sequence lengths and genomic regions. Mol Biol Evol, 24(1), 23-5, 2007.
- Sun, J, Li, Y, Zhao, Z Phylogenetic profiles for the prediction of protein-protein interactions: how to select reference organisms. Biochem Biophys Res Commun, 353(4), 985-91, 2007.
- Seo, D, Jiang, C, Zhao, Z A novel statistical method to estimate the effective SNP size in vertebrate genomes and categorized genomic regions. BMC Genomics, 7329, 2006.
- Jiang, C, Zhao, Z Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome. BMC Genomics, 7316, 2006.
- Jiang, C, Zhao, Z Mutational spectrum in the recent human genome inferred by single nucleotide polymorphisms. Genomics, 88(5), 527-34, 2006.
- Zhao, Z, Yu, N, Fu, YX, Li, WH Nucleotide variation and haplotype diversity in a 10-kb noncoding region in three continental human populations. Genetics, 174(1), 399-409, 2006.
- Zhao, Z, Zhang, F Sequence context analysis in the mouse genome: single nucleotide polymorphisms and CpG island sequences. Genomics, 87(1), 68-74, 2006.
- Zhao, Z, Zhang, F Sequence context analysis of 8.2 million single nucleotide polymorphisms in the human genome. Gene, 366(2), 316-24, 2006.
- Citovsky, V, Lee, LY, Vyas, S, Glick, E, Chen, MH, Vainstein, A, Gafni, Y, Gelvin, SB, Tzfira, T Subcellular localization of interacting proteins by bimolecular fluorescence complementation in planta. J Mol Biol, 362(5), 1120-31, 2006.
- Yang, S, Liu, Y, Lin, AA, Cavalli-Sforza, LL, Zhao, Z, Su, B Adaptive evolution of MRGX2, a human sensory neuron specific gene involved in nociception. Gene, 35230-5, 2005.
- Zhang, F, Zhao, Z SNPNB: analyzing neighboring-nucleotide biases on single nucleotide polymorphisms (SNPs). Bioinformatics, 21(10), 2517-9, 2005.
- Zhao, Z, Li, H, Wu, X, Zhong, Y, Zhang, K, Zhang, YP, Boerwinkle, E, Fu, YX Moderate mutation rate in the SARS coronavirus genome and its implications. BMC Evol Biol, 421, 2004.
- Zhang, F, Zhao, Z The influence of neighboring-nucleotide composition on single nucleotide polymorphisms (SNPs) in the mouse genome and its comparison with human SNPs. Genomics, 84(5), 785-95, 2004.
- Zhao, Z, Fu, YX, Hewett-Emmett, D, Boerwinkle, E Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution. Gene, 312207-13, 2003.
- Mijit, G, Zayadan, BK, Rahman, E, Chunaev, AS [Analysis of dominant-recessive mutated character of nfr genes of Chlamydomonas reinhardtii and its mutual interaction with the chloroplastic psbA gene]. Yi Chuan Xue Bao, 30(7), 646-52, 2003.
- Zhao, Z, Boerwinkle, E Neighboring-nucleotide effects on single nucleotide polymorphisms: a study of 2.6 million polymorphisms across the human genome. Genome Res, 12(11), 1679-86, 2002.
- Yu N, Zhao Z, Fu Y-X, Sambuughin N, Ramsay M, Jenkins T, Leskinen E, Patthy L, Jorde LB, Kuromori T, Li W-H Global patterns of human DNA sequence variation in a 10-kb region on chromosome 1. Molecular Biology and Evolution , 18(2), 214-222, 2001.
- Zhao Z, Jin L, Fu Y-X, Ramsay M, Jenkins T, Leskinen E, Pamilo P, Trexler M, Patthy L, Jorde LB, Ramos-Onsins S, Yu N, Li W-H Worldwide DNA sequence variation in a 10 kb noncoding region on human chromosome 22. Proc. Natl. Acad. Sci. USA, 97(21), 11354-11358, 2000.
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