News: Cancer Research

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Protein “pockets” help ID cancer genes

Tuesday, November 11th, 2014

Somatic mutations, which can occur in any cell except sperm or egg, are not inheritable. Several recent studies have demonstrated that disease-causing mutations commonly alter protein folding, protein stability and protein-protein interactions. It has been difficult, however, to determine which somatic mutations identified in tumor samples “drive” the cancer development and which are just “along […]

Immune cell activity and melanoma

Thursday, November 6th, 2014

Melanoma, the most lethal form of skin cancer, spreads aggressively and is often resistant to therapy. Melanoma tumor formation is driven in part by nuclear factor-kappa B (NF-kappaB)-mediated gene transcription, and loss of NF-kappaB activity can block melanoma tumor formation. However, NF-kappaB also plays a crucial role in immune cells. In an October online edition […]

New Insights on Postpartum Breast Cancer

Friday, October 31st, 2014

A new study explaining the cellular activity that leads to breast tumor metastasis among women who have recently given birth may offer new treatment direction for postpartum breast cancer.

Key to Prostate Cancer Resistance

Friday, October 31st, 2014

Findings suggest a combination of therapies that may be effective in treating resistant prostate cancers

Study Finds New Role for Cell Factor

Friday, October 31st, 2014

Vanderbilt University investigators have discovered a new molecular mechanism that regulates the dynamics of microtubules, which form the cell’s internal skeleton. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery,

Aspirin’s Protective Effect in Cancer Explained

Thursday, October 2nd, 2014

For years, scientists have known that regular aspirin use may reduce the risk of cancer. “Studies have shown that aspirin administration for five or more years reduces the incidence of all cancers by 38 percent,” said Pierre Massion, M.D., professor of Medicine and Cancer Biology and director of the Thoracic Program at Vanderbilt-Ingram Cancer Center. […]

Report Calls for Added Cancer Research Support

Thursday, September 25th, 2014

The American Association for Cancer Research (AACR) Cancer Progress Report 2014, released Sept. 16, details advances in cancer research and treatment — and calls for increased research support.

Accuracy of Lung Imaging Varies by Region

Wednesday, September 24th, 2014

FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common, a recent study has found.

Grant Spurs Lung Cancer Surgery Research

Thursday, September 18th, 2014

Joe B. (Bill) Putnam Jr., M.D., Ingram Professor of Cancer Research and chair of the Department of Thoracic Surgery, and colleague Felix Fernandez, M.D., assistant professor of Surgery, Emory University School of Medicine, Atlanta, have received a grant to investigate the most effective forms of surgery to treat lung cancer patients.

Engelhardt Lands Stem Cell Transplant Grant

Thursday, September 11th, 2014

Brian Engelhardt, M.D., MSCI, assistant professor of Medicine, has received a Mentored Career Development Award from the National Heart, Lung, and Blood Institute, a division of the National Institutes of Health, to explore the causes of post-transplant diabetes development.