Vanderbilt-Ingram Cancer Center

Vanderbilt-Ingram Cancer Center has initiated tumor mutation testing for a limited number of patients with metastatic colorectal cancer. This pilot project for colorectal cancer is part of VICC’s Personalized Cancer Medicine Initiative (PCMI), a program to identify genetic mutations in a patient’s tumor that may be useful in matching the appropriate therapy with each patient. [...]

Vanderbilt-Ingram Cancer Center cordially invites you and your guests to join us for Going for the Gold: Living Well through Cancer! Due to an overwhelming response, we have closed registration. We are thrilled to have so many people attend! Date: Saturday, June 30, 2012 Time: 9:30 a.m.-2:30 p.m. Where: Vanderbilt University Student Life Center 310 [...]

Vanderbilt-Ingram Cancer Center researchers have identified a new population of intestinal stem cells that may hold clues to the origin of colorectal cancer. This new stem cell population, reported March 30 in the journal Cell, appears to be relatively quiescent (inactive) – in contrast to the recent discovery of intestinal stem cells that multiply rapidly [...]

Colon cancer development and progression involves alterations in several cell signaling pathways. Activation of the Wnt pathway is involved in the early stages of tumor development, while inactivation of signaling through the TGF-beta pathway (which typically suppresses tumor formation) is involved in later stages. However, the interactions between these pathways remain unclear. R. Daniel Beauchamp, [...]

Join us on March 20 for a FREE informative evening on your health and wellness. Event is located at Vanderbilt-Ingram Cancer Center at Green Hills 3810 Bedford Avenue Suite 100 Nashville, TN 37215 6 p.m. Registration & Refreshments 6:30 p.m. Speaker 7:15 p.m. Questions & Answers Quitting tobacco is the best thing that you can [...]

About half of colorectal tumors express elevated levels of COX-2, the key enzyme responsible for generating prostaglandins that promote cancer development. Prostaglandin E2 (PGE2) is likely the primary mediator of most of COX-2’s tumor-promoting effects, and the PGE2 metabolite, PGE-M, can be measured noninvasively in urine. To assess the utility of PGE-M as a biomarker [...]

A few years ago, Alison Hanson, Ph.D., a student in Vanderbilt’s Medical Scientist Training Program, was invited to have lunch with a visiting Nobel laureate, Aaron Ciechanover, M.D., D.Sc. Hanson was working on her dissertation research at the time, and she described some interesting findings to Ciechanover. “He said, ‘that could either be a total [...]

Everyone is encouraged to wear something blue to spark conversations about the importance of early screening for colon cancer during Dress in Blue Day on Friday, March 2. Dress in Blue Day was launched in 2009 by the Colon Cancer Alliance to raise awareness about colorectal cancer, which is the second leading cause of cancer-related [...]

Women who eat at least three servings of fish per week have a reduced risk of developing some types of colon polyps, according to a new study by Vanderbilt-Ingram Cancer Center investigators. The research, led by first author Harvey Murff, M.D., MPH, associate professor of Medicine, was published recently in the American Journal of Clinical [...]

Individuals who are outside the “normal” range of expression for the APC gene have an increased risk of colorectal cancer, according to a study published in the January issue of Gastroenterology. Mutations in the APC (adenomatous polyposis coli) gene – and variations in the expression of the gene’s two copies (allele-specific expression) — are associated [...]