News: Drug Discovery

Next Page »

Proteins May Point to Prostate Cancer Drug Targets

Tuesday, August 7th, 2012

Two proteins that act in opposing directions – one that promotes cancer and one that suppresses cancer — regulate the same set of genes in prostate cancer, Vanderbilt-Ingram Cancer Center researchers have found. The findings, reported recently in the Journal of Clinical Investigation, point toward potential drug targets and prognostic markers for prostate cancer. “We […]

Uncommon BRAF Melanoma Mutation

Wednesday, July 18th, 2012

An uncommon mutation of the BRAF gene in melanoma patients has been found to respond to MEK inhibitor drugs, providing a rationale for routine screening and therapy in melanoma patients who harbor the BRAF L597 mutation. The new study by co-first-authors Kimberly Brown Dahlman, Ph.D., Junfeng Xia, Ph.D., and Katherine Hutchinson, B.S., Vanderbilt-Ingram Cancer Center […]

New Cancer Drug Shows Promise

Thursday, July 12th, 2012

An experimental drug that activates T-cells and promotes an immune response to fight tumors has shown promising early results in patients with kidney cancer, melanoma and non-small cell lung cancer. Vanderbilt-Ingram Cancer Center investigators Leora Horn, M.D., Jeffrey Sosman, M.D., and researchers from several other cancer centers tested the new compound. The results of the […]

Fesik’s Cancer Research Achievements Honored

Friday, March 30th, 2012

Stephen Fesik, Ph.D., professor of Biochemistry, Pharmacology and Chemistry at Vanderbilt, will receive the 2012 AACR Award for Outstanding Achievement in Chemistry in Cancer Research. Fesik, who holds the Orrin H. Ingram II chair in cancer research, will receive the special recognition during the American Association for Cancer Research (AACR) Annual Meeting in Chicago March […]

My Health Chat: Cancer Drug Discovery

Thursday, March 22nd, 2012

The April program for My Health Chat will be the promising world of cancer drug discovery. Panelists will be Lawrence Marnett, Ph.D., director of the Vanderbilt Institute of Chemical Biology, and Stephen Fesik, Ph.D., director of drug discovery at Vanderbilt-Ingram Cancer Center. They will be discussing and taking questions about how information about the genetic […]

Carroll Wins Vanderbilt’s First Damon Runyon Fellowship

Friday, January 27th, 2012

Mary Carroll, Ph.D., a postdoctoral research fellow in Biochemistry, was recently named one of 18 Damon Runyon Fellows by the Damon Runyon Cancer Research Foundation. The three-year, $156,000 award provides independent funding for outstanding postdoctoral scientists to pursue innovative projects. Carroll is the first postdoctoral fellow from Vanderbilt to receive this award. “I am honored […]

VUMC Teams with 3 Midstate Hospitals

Friday, September 23rd, 2011

Leaders of Vanderbilt University Medical Center, Maury Regional Medical Center, Northcrest Medical Center and Williamson Medical Center today announced affiliation agreements establishing a partnership between these medical centers to work collaboratively to create new jointly operated programs and services in the counties where these hospitals reside. These programs are intended to expand primary and specialty […]

Guengerich Lauded for Contributions

Friday, September 2nd, 2011

F. Peter (Fred) Guengerich, Ph.D., interim chair of the Department of Biochemistry, received the American Chemical Society Division of Chemical Toxicology Founders’ Award at the society’s annual meeting this week. The award recognizes Guengerich’s outstanding research accomplishments and his numerous contributions to the field of chemical toxicology. “This means a lot to me in that […]

Never Give Up, Lance’s Mom Says

Thursday, June 23rd, 2011

In 1971 — coincidentally the year that President Nixon declared the War on Cancer — a 16-year-old gave birth in Plano, Texas, to a baby boy that she named Lance. He would grow up to become a champion cyclist and arguably the most famous cancer survivor on the planet. Dressed in the trademark yellow of […]

Cancer Survivors’ Day Highlights

Tuesday, June 21st, 2011

More than 350 cancer survivors, caregivers, advocates and health professionals gathered at the Vanderbilt Student Life Center last Saturday (June 18, 2011) to learn, connect and celebrate. Cancer GPS: Navigating Your Journey included remarks from keynote speaker Linda Armstrong Kelly (author and mother of champion cyclist and survivor Lance Armstrong), music and stories from survivor, […]