News: Aliquots

Spicing Up Cancer Prevention

Tuesday, January 25th, 2011

Curcumin – the active ingredient that flavors curries and gives the Indian spice turmeric its yellow color – is being studied for its ability to prevent tumor development. Its efficacy, however, is limited by chemical and metabolic instability. Previous studies have focused on the non-enzymatic (not mediated by a protein) cleavage of curcumin into smaller […]

Detour Around the Estrogen Receptor

Tuesday, January 25th, 2011

About 75 percent of early-stage breast cancers are fueled by estrogen. These estrogen receptor (ER)-positive tumors typically respond to anti-estrogen therapies like tamoxifen, but about a quarter of patients develop resistance to these therapies and the tumors recur. A multi-institutional team of researchers has now identified a potential new target for treating these tumors. The […]

DNA ‘Marks’ Gastric Cancer Risk

Tuesday, January 25th, 2011

Infection with the stomach-dwelling bacterium Helicobacter pylori is a strong risk factor for gastric cancer. But since about half of the world’s population is infected, and less than 1 percent of infected individuals develop cancer, other factors must contribute to gastric cancer risk. Barbara Schneider, Ph.D., and colleagues are examining the role of epigenetic factors […]