News: biomarker

Urine Biomarker for Colon Cancer?

Friday, March 2nd, 2012

About half of colorectal tumors express elevated levels of COX-2, the key enzyme responsible for generating prostaglandins that promote cancer development. Prostaglandin E2 (PGE2) is likely the primary mediator of most of COX-2’s tumor-promoting effects, and the PGE2 metabolite, PGE-M, can be measured noninvasively in urine. To assess the utility of PGE-M as a biomarker […]

“Did You Smoke?”

Wednesday, December 8th, 2010

When Martha McCann Lesnick’s granddaughter was about 6 years old, she asked her grandmother about the yellow LiveStrong wristband she wore. Lesnick explained that she wore it because she was fighting lung cancer. Her granddaughter replied: “oh yeah, that’s because…what did you do?” “She was talking about smoking,” says Lesnick, a Nashville songwriter and four-year […]

Grants to Fund Research on Early Detection

Thursday, November 4th, 2010

The National Cancer Institute has awarded two Early Detection Research Network (EDRN) grants to a group of Vanderbilt-Ingram Cancer Center investigators to support early detection of lung and colon cancers. Pierre Massion, M.D., associate professor of Medicine and Cancer Biology, has been awarded $3 million over five years for the creation of the Vanderbilt Clinical […]