News: Gastroenterology

VICC’s Correa Honored with AACR Lectureship

Friday, April 13th, 2012

Pelayo Correa, M.D., professor of Pathology, Microbiology and Immunulogy, has been recognized by the American Association for Cancer Research (AACR) and its Minorities in Cancer Research membership group with the Jane Cooke Wright Lectureship. Correa holds the Anne Potter Wilson chair in cancer research in the Division of Gastroenterology, Hepatology and Nutrition. The AACR-MICR-Jane Cooke […]

Colon Cancer’s Cellular Crossroads

Friday, March 16th, 2012

Colon cancer development and progression involves alterations in several cell signaling pathways. Activation of the Wnt pathway is involved in the early stages of tumor development, while inactivation of signaling through the TGF-beta pathway (which typically suppresses tumor formation) is involved in later stages. However, the interactions between these pathways remain unclear. R. Daniel Beauchamp, […]

Colorectal Cancer Risk Related to Gene’s Expression

Friday, January 27th, 2012

Individuals who are outside the “normal” range of expression for the APC gene have an increased risk of colorectal cancer, according to a study published in the January issue of Gastroenterology. Mutations in the APC (adenomatous polyposis coli) gene – and variations in the expression of the gene’s two copies (allele-specific expression) — are associated […]

Pathway to Colon Cancer Progression

Friday, December 2nd, 2011

Identifying the molecular pathways that lead normal colon cells to become cancer cell could provide much needed biomarkers and therapeutic targets. Previously, Punita Dhawan, Ph.D., and colleagues showed that claudin-1 – a protein member of “tight junctions” that help bind cells together into an organized tissue structure – was greatly increased and mislocalized in colorectal […]

Peek Honored by Gastroenterology Group

Friday, March 25th, 2011

Richard Peek Jr., M.D., the Mina Cobb Wallace professor of Gastroenterology and Cancer Biology and Director of the Division of Gastroenterology, Hepatology, and Nutrition at Vanderbilt, has been elected chair of the American Gastroenterological Association (AGA) Council. The AGA Institute Council is comprised of 24 elected representatives from 12 topic interest groups that address the […]