News: gene

Colon Cancer Added to Gene Mutation Testing

Thursday, July 19th, 2012

Vanderbilt-Ingram Cancer Center has initiated tumor mutation testing for a limited number of patients with metastatic colorectal cancer. This pilot project for colorectal cancer is part of VICC’s Personalized Cancer Medicine Initiative (PCMI), a program to identify genetic mutations in a patient’s tumor that may be useful in matching the appropriate therapy with each patient. […]

New Drug Mutes More Melanomas

Thursday, April 26th, 2012

Therapies targeted to a specific mutation in the BRAF gene can significantly reduce tumor burden in metastatic melanoma. But these therapies are not suitable for melanomas lacking the mutation, and even tumors carrying the BRAF mutation eventually become resistant to those therapies. Using human melanoma tumors implanted into mice, Ann Richmond, Ph.D., and colleagues assessed […]

Cancer Gene’s Role in Outcomes Prediction

Friday, March 25th, 2011

A new study by Vanderbilt-Ingram Cancer Center investigators reveals that a gene signature may be useful in predicting outcomes for patients with rhabdomyosarcoma, a form of cancer most commonly diagnosed in children. The study, carried out by first author Jennifer Rosenbluth, Ph.D.; Jennifer Pietenpol, Ph.D., professor of Biochemistry, Cancer Biology and Otolaryngology and director of […]