Individuals who are outside the “normal” range of expression for the APC gene have an increased risk of colorectal cancer, according to a study published in the January issue of Gastroenterology. Mutations in the APC (adenomatous polyposis coli) gene – and variations in the expression of the gene’s two copies (allele-specific expression) — are associated [...]
Endometrial cancer, or cancer of the uterine lining, is the most common gynecological malignancy. Obesity – defined as a body mass index (BMI) of 30 or higher – is a well-established risk factor for endometrial cancer, with obese women having a 4- to 6-times higher risk of the malignancy than nonobese women. Ryan Delahanty, Ph.D., [...]
Dr. Emily Chan, a medical oncologist at Vanderbilt-Ingram Cancer Center, discusses hereditary pancreatic cancer and what is done to follow those showing concerns of developing the cancer. She encourages patients to research clinical trials since the current therapies for pancreatic cancer need improvement.
Since the first of the year, one cutting-edge sequencer, the Illumina HiSeq 2000, has been installed in a lab in the Preston Research Building, and another has been delivered. More than 30 Vanderbilt investigators have submitted samples for sequencing by the machines, which are not much bigger than half-size refrigerators.“The access to this technology allows [...]