News: National Cancer Institute

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Drugs Reverse Lung Cancer Cell Changes

Friday, February 3rd, 2012

The protein transforming growth factor β (TGF-β) can act as either a tumor suppressor or a tumor promoter depending on the stage of cancer. Loss of TGF-β’s tumor suppressor activity may play an important role in lung cancer progression. Pran Datta, Ph.D., and colleagues previously showed that this loss of responsiveness to TGF-β occurs mainly […]

Pink Out! Game to Tip Off Jan. 29

Friday, January 27th, 2012

Pink will be the color of the day during the Vanderbilt Commodore Women’s Basketball Team Pink Out! event to raise awareness for breast cancer research Sunday, Jan. 29, at 2 p.m. The Commodores will wear pink uniforms in their matchup in Memorial Gymnasium against the LSU Tigers. Fans are also invited to wear pink, the […]

Obesity Genes Linked to Uterine Cancer

Friday, January 20th, 2012

Endometrial cancer, or cancer of the uterine lining, is the most common gynecological malignancy. Obesity – defined as a body mass index (BMI) of 30 or higher – is a well-established risk factor for endometrial cancer, with obese women having a 4- to 6-times higher risk of the malignancy than nonobese women. Ryan Delahanty, Ph.D., […]

My Cancer Genome Wins Technology Award

Friday, January 13th, 2012

Vanderbilt-Ingram Cancer Center physician-scientists who created the new online medical decision support tool called “My Cancer Genome” have been named winners of a $20,000 health care technology award sponsored by the National Cancer Institute. The contest, “Using Public Data for Cancer Prevention and Control: From Innovation to Impact Developer Challenge,” was presented as part of […]

Grant Bolsters Cancer Research

Friday, January 13th, 2012

The National Cancer Institute has renewed a $4.4 million, five-year grant to fund training for senior fellows and junior faculty for careers in cancer-oriented research. The goal of the Vanderbilt Clinical Oncology Research Career Development Program is to train clinician scientists who can design and implement clinical oncology trials and lead translational research projects. The […]

VICC Named to Proteomic Cancer Research Consortium

Thursday, December 8th, 2011

A team of Vanderbilt-Ingram Cancer Center scientists, led by Daniel Liebler, Ph.D., professor of Biochemistry, Biomedical Informatics and Pharmacology, has been selected to participate in the Clinical Proteomic Tumor Analysis Consortium (CPTAC), a multi-center cancer research program created by the National Cancer Institute (NCI). Liebler will lead the Vanderbilt Proteome Characterization Center, one of five […]

Lung Resections Not Always “Futile”

Friday, December 2nd, 2011

The gold standard for definitive diagnosis of a lung nodule is surgical removal (resection). However, between 10 percent and 30 percent of suspicious nodules are benign. Because thoracic operations are highly invasive and pose significant risks, these operations have been labeled “unnecessary” or “futile.” Eric Grogan, M.D., M.P.H., and colleagues report that, even when surgical […]

Pathway to Colon Cancer Progression

Friday, December 2nd, 2011

Identifying the molecular pathways that lead normal colon cells to become cancer cell could provide much needed biomarkers and therapeutic targets. Previously, Punita Dhawan, Ph.D., and colleagues showed that claudin-1 – a protein member of “tight junctions” that help bind cells together into an organized tissue structure – was greatly increased and mislocalized in colorectal […]

Protein Family Linked to Suppressing Tumors

Friday, October 28th, 2011

The list of aging-associated proteins known to be involved in cancer is growing longer, according to research by investigators at Vanderbilt-Ingram Cancer Center and the National Institutes of Health (NIH). The new study, published Oct. 17 in Cancer Cell, identifies the protein SIRT2 as a tumor suppressor linked to gender-specific tumor development in mice. Along […]

MyCancerGenome Finalist for Tech Award

Friday, October 28th, 2011

MyCancerGenome, the online medical decision support tool for cancer care developed by Vanderbilt physician-scientists, has been selected as a finalist for a health care technology award. The contest, “Using Public Data for Cancer Prevention and Control: From Innovation to Impact Developer Challenge,” is sponsored by the National Cancer Institute (NCI), Division of Cancer Control and […]