News: R. Daniel Beauchamp

Colon Cancer’s Cellular Crossroads

Friday, March 16th, 2012

Colon cancer development and progression involves alterations in several cell signaling pathways. Activation of the Wnt pathway is involved in the early stages of tumor development, while inactivation of signaling through the TGF-beta pathway (which typically suppresses tumor formation) is involved in later stages. However, the interactions between these pathways remain unclear. R. Daniel Beauchamp, […]

Studies Pinpoint New Anti-Cancer Drug Target

Friday, February 24th, 2012

A few years ago, Alison Hanson, Ph.D., a student in Vanderbilt’s Medical Scientist Training Program, was invited to have lunch with a visiting Nobel laureate, Aaron Ciechanover, M.D., D.Sc. Hanson was working on her dissertation research at the time, and she described some interesting findings to Ciechanover. “He said, ‘that could either be a total […]

Study Seeks Clues to Halt Metastasis’ March

Friday, July 22nd, 2011

Cancer cells grow in a seemingly haphazard fashion. They have lost the ability to connect with neighboring cells in a normal, well-ordered way. Instead, these microscopic “pirates” have acquired the ability to invade normal tissues and to wreak damage long distances through a process known as “metastasis.” E-cadherin, a protein that “glues” normal cells together, […]

Caring for the Whole Patient

Wednesday, December 8th, 2010

For more than 30 years, surgical nurse Carolyn Watts, M.S.N., R.N., has tended to patients’ wounds. But healing, she notes, is about more than just the physical wounds. As she often tells nursing students: “Look at the whole patient, and not just the hole in the patient.” This holistic approach is especially important in cancer […]