News: stroma

Proteins Guard Against Cancer Spread

Thursday, July 26th, 2012

Prostate cancer cells metastasize mainly to bone, yet bone metastases are resistant to common therapies and are often fatal. A key receptor for the growth factor TGF-β (TβRII) is lost in the connective tissue (stroma) of most prostate cancers, but the effects of this loss on metastasis and bone lesion development are undefined. Recently in […]