Picture a railroad track, running across the countryside. DNA looks something like that track. Its “rails” are chains of chemicals called nucleotides, each pairing with a partner on the opposite chain to form the “ties.” To ensure timely train traffic – and prevent catastrophic derailments – the railroad track needs regular maintenance. So does DNA. [...]
News: targeted therapy
A new drug used to treat advanced melanoma patients with a specific genetic mutation in their tumors demonstrated significant tumor shrinkage in the majority of patients during a clinical trials.
The Melanoma Research Alliance has awarded a three-year, $2 million grant to a multi-center team of cancer researchers investigating resistance to a new family of BRAF-targeted kinase inhibitor drugs. These targeted therapies are being tested in melanoma patients whose tumors carry a specific genetic mutation known as V600E BRAF. Jeff Sosman, M.D., professor of Medicine [...]