Vanderbilt-Ingram Cancer Center

Internationally known toxicologist F. Peter (Fred) Guengerich, Ph.D., is stepping down as director of the Vanderbilt University Center in Molecular Toxicology, a position he has held for 30 years. Effective this month, Michael Aschner, Ph.D., became the new principal investigator (PI) of the center’s P30 core grant and the T32 training grant in Environmental Toxicology. [...]

Aflatoxins – carcinogenic toxins produced by fungi – contaminate food. Aflatoxin B1 has been implicated in the development of human liver cancer. A metabolite of aflatoxin B1 reacts with DNA, forming adducts that cause mutations. To understand how different chemical forms of such adducts induce differing levels of mutations, Surajit Banerjee, Ph.D., Kyle Brown, Ph.D., [...]