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CCSG Collaborative Research Initiatives

Vanderbilt-Ingram Cancer Center (VICC) is dedicated to an integrated and patient-focused approach to cancer research, treatment, support, prevention, education and outreach. As one of the top ten National Cancer Institute (NCI) comprehensive cancer centers, Vanderbilt-Ingram Cancer Center (VICC) is a matrix center within Vanderbilt University Medical Center (VUMC), and the VICC integrates the cancer-related expertise and resources of the School of Medicine, School of Nursing, School of Arts and Sciences, School of Engineering, and Peabody School of Education as well as the fully integrated Veterans Administration Medical Center (VAMC). The Frances W. Preston Research Building is the focal point of VICC activities and includes the primary cancer clinic, wet and dry laboratory space for numerous basic and translational investigators, shared resources and office space for faculty and administration. Other research, clinical, educational and administrative facilities are located in close proximity on the same campus, a situation that promotes interactions, sharing of resources and contributes to the strong collaborative culture at Vanderbilt.

Established in 1993, the VICC functions as an organizational unit with a supra-departmental status. The VICC's specific authorities and responsibilities are: 1) to conduct coordinate and integrate the cancer and cancer-related activities of Vanderbilt University; 2) to conduct, support and enhance cancer research and to integrate cancer-related activities throughout the University; 3) to integrate, develop and conduct cancer education programs; and 4) to coordinate and integrate the care of cancer patients at VUMC and VAMC. The research objectives are accomplished by more than 300 members through eight research programs that include: Breast Cancer; Cancer Epidemiology; Cancer Health Outcomes and Control; Gastrointestinal Cancer; Genome Maintenance; Host-Tumor Interactions; Signal Transduction and Chemical Biology; and Translational Research and Interventional Oncology. Thirteen Shared Resources providing cutting-edge, state-of-the-art services are established to support the outstanding scientists and programs of the VICC.

There has been remarkable progress in the development of the VICC over the past five years. As an NCI-designated center, VICC focuses on collaboration and high-impact science that includes basic, translational and population-based research, cancer prevention/control and innovative, high-quality cancer treatment including the latest in clinical trials. The collaborative atmosphere has resulted in an overall peer-reviewed cancer-relevant base of $142.2 million. With NCI funding of $65.3 million, VICC is ranked 7th in total NCI funding among NCI-designated cancer centers and 3rd among matrix cancer centers. VICC is home to two NCI-funded Specialized Programs of Research Excellence (SPOREs) grants in breast and gastrointestinal cancer, three major epidemiologic cohort studies that include the Southern Community Cohort, Women's Shanghai Cohort, and Men's Shanghai Cohort, two Early Detection Research Network grants for colorectal and lung cancers and a Minority Institution/Cancer Center Partnership with Meharry Medical College and Tennessee State University. Research is conducted in each of the NIH-designated priority areas: high-throughput technologies, translational medicine, comparative effectiveness, prevention, precisionmedicine, health disparities, pharmacogenomics and global health.