The SPORE in Breast Cancer: Research

Career Development

Specific actions have been taken by Vanderbilt University Medical Center and the Vanderbilt-Ingram Cancer to improve the quantity and quality of opportunities for training in translational research for physicians and physician-scientists.

Therefore, the goal of the Career Development Program is to provide individuals with the training necessary for them to not only have successful and independent careers in translational breast cancer research but also the opportunity to reorient productive research programs to focus on breast cancer.

During the current cycle, the SPORE Career Development Program has supported 8 investigators, 2 in the physician-scientist/clinical investigator track and 6 in the basic scientist track. Four of the awardees, Drs. Mayer, Sanders, Xu, and Wang, have obtained extramural grants for a total combined budget of $1,533,310 (direct and indirect costs). This return in extramural grant dollars far surpasses the investment made in the Program. In addition, Dr. Cortez submitted an R21 application which scored in the 2.7 percentile. Dr. Ritchie has submitted an R01 application which was scored and is being prepared for resubmission. Importantly, the 2 clinical/translational investigators (Drs. Sanders and Mayer) supported by the Program are co-investigators in this competing renewal application. Five of the 8 awardees during the current 5-year grant period are women. Six of the 8 awardees are junior faculty and 4 of these have obtained extramural peer-reviewed funding. Titles of these projects and grants and publications as a result of these awards are summarized in the Table below. They are included in more detail in the Career Development Program section of this application (C. Progress Report). URLs for most of these manuscripts are included in the Appendix.

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