- Project 1: Biological and Therapeutic Implications of Blockade of EGFR Axis and Src in Colorectal Cancer
Clinical PI: Nipun B. Merchant, M.D.
Basic PI: Robert. J. Coffey, M.D.
Patient Advocate: Stephanie Crowe
- Project 2: Chemical Genetics Approach to Interrogate and Regulate E-Cadherin Expression and Canonical Wnt Signaling
Clinical PI: R. Daniel Beauchamp, M.D.
Basic PI: Ethan Lee, M.D., Ph.D.
Patient Advocate: Ron Obenauf
- Project 3: Understanding and Controlling p120 Dysfunction in Colorectal Cancer
Clinical PI: Mary Kay Washington, M.D., Ph.D.
Basic PI: Albert B. Reynolds, Ph.D.
Patient Advocate: Diane Lancaster
- Project 4: Tennessee Colorectal Polyp Study
Clinical PI: Reid M. Ness, M.D., M.P.H.
Basic PI: Wei Zheng, M.D., Ph.D.
Project Director: Martha J. Shrubsole, Ph.D.
Patient Advocates: Ardeth Obenauf