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Clinical Trials Search at Vanderbilt-Ingram Cancer Center

Predicting the Quality of Response to Specific Treatments in Patients with cGVHD, PQRST Study

This trial collects clinical data and blood samples to predict the quality of response to specific treatments in patients with chronic graft-versus-host disease (cGVHD) who are about to start initial or second-line therapy. Collecting and analyzing clinical data and blood samples from patients with cGVHD before and after treatment initiation may help doctors identify changes that may predict treatment response.
Miscellaneous
N/A
Adults
Not Available
Not Available
Kitko, Carrie
International
Vanderbilt University
03-09-2021
Other
VICCCTT2082
NCT04431479

Eligibility

18 Years
BOTH
NO
Inclusion Criteria:

Prior allogeneic stem cell transplant, with any graft source, donor type, and GVHD prophylaxis

No evidence of persistent or progressive malignancy at the time of enrollment

Agrees to be evaluated at the transplant center before initial or second-line treatment is started (may be concurrent with the enrollment visit), and later between 2-6 weeks, 3 months and 6 months after treatment is started or if a new therapy is started before 6 months

Signed, informed consent



Exclusion Criteria:

Inability to comply with study procedures

Uncontrolled psychiatric disorder

Anticipated survival

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