Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors
Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors
To compare donors to their non-donor counterparts and healthy controls as well as to generate
trajectory classes based on longitudinal patterns of donor HRQoL and identify predictors of
poor donor HRQoL.
trajectory classes based on longitudinal patterns of donor HRQoL and identify predictors of
poor donor HRQoL.
Pediatrics
N/A
Children
Not Available
Not Available
Kitko, Carrie
National
Vanderbilt University
05-12-2020
Other
VICCPED1949
NCT03718546
Eligibility
5 Years
BOTH
YES
Inclusion Criteria:
Participants must fall into one of the following categories:
Donor between the age of 5 and 17 who is donating to a sibling
Parent/caregiver of study participating donor
Recipient sibling aged 5 to 17 of study participating donor
Any of the donor's non-donor/non-recipient siblings between 5 and 17
Any child between 5 and 17 with a brother or sister (also between 5 and 17) receiving a transplant from an unrelated source
Be willing and able to provide signed informed consent:
Adults must give consent for their children's and, if applicable, their own participation
Assent will be obtained in accordance with guidelines at the participant's transplant institution
Be willing and able to respond to psychological assessment questions
Must be the donor's first donation
Recipient must consent to the CIBMTR research database
Exclusion Criteria:
For families with pediatric donors aged 5 to 17, at minimum, the donor child and/or one parent must consent/assent to participation. If that minimum is not met, the family will be excluded
Donor or non-donor siblings who do not live in the same household as the recipient at lease half of the time
Unable to consent/assent or complete a phone interview in English
Parents may consent/assent in Spanish
No access to a telephone
Participants must fall into one of the following categories:
Donor between the age of 5 and 17 who is donating to a sibling
Parent/caregiver of study participating donor
Recipient sibling aged 5 to 17 of study participating donor
Any of the donor's non-donor/non-recipient siblings between 5 and 17
Any child between 5 and 17 with a brother or sister (also between 5 and 17) receiving a transplant from an unrelated source
Be willing and able to provide signed informed consent:
Adults must give consent for their children's and, if applicable, their own participation
Assent will be obtained in accordance with guidelines at the participant's transplant institution
Be willing and able to respond to psychological assessment questions
Must be the donor's first donation
Recipient must consent to the CIBMTR research database
Exclusion Criteria:
For families with pediatric donors aged 5 to 17, at minimum, the donor child and/or one parent must consent/assent to participation. If that minimum is not met, the family will be excluded
Donor or non-donor siblings who do not live in the same household as the recipient at lease half of the time
Unable to consent/assent or complete a phone interview in English
Parents may consent/assent in Spanish
No access to a telephone
