Clinical Trials Search at Vanderbilt-Ingram Cancer Center

Evaluation of Patient Reported Outcomes in Patients with Digestive System and Lung Neuroendocrine Cancer, NET-PRO study

Gastrointestinal

This study evaluates the patient reported outcomes in patients with digestive system neuroendocrine cancer and lung neuroendocrine cancer. Patients with neuroendocrine cancer usually have a high symptom burden which may have a negative effect on health-related quality of life (HRQoL). Patient questionnaires gather information describing symptoms and effect on quality of life, cancer type and any treatments received. Studying quality of life in patients receiving treatment for neuroendocrine cancers may help identify the effects of treatment and improve future treatment plans. Information gathered from this study may help researchers understand whether patient's diagnosis, symptoms, and order of cancer treatments have any effect on quality of life.

Disease Sites: Gastrointestinal

Phase: N/A

Investigator: Ramirez, Robert

NCTID: NCT05064150

Protocol No: VICCGI2247

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A Study Evaluating an Advanced Pneumatic Compression Device Versus Usual Care for Treatment of Head and Neck Lymphedema

Head/Neck

To compare the effectiveness of an APCD to Usual Care in the management of lymphedema and
fibrosis (LEF) in head and neck cancer (HNC) survivors.

Disease Sites: Head/Neck

Phase: N/A

Investigator: Murphy, Barbara

NCTID: NCT04797390

Protocol No: VICCHN2111

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Sparing Bone Marrow in Patients with Stage IIB-IV Lung Cancer, VMAT Trial

Lung

This phase II trial tests whether designing radiation to avoid bone marrow in the spine (vertebral bone marrow) leads to less reduction of white blood cell counts (lymphopenia) in patients with lung cancer. This sparing technique could lead to better disease control and outcome.

Disease Sites: Lung

Phase: N/A

Investigator: Osmundson, Evan

NCTID: NCT05248256

Protocol No: VICCRAD2189

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Fluid Measurements and MRI in Determining Biomarkers of Lymphatic Dysfunction in Patients with Breast Cancer

Breast

This trial uses fluid measurements of the arm and MRI to determine biomarkers of lymphatic dysfunction in patients with breast cancer. Studying the lymphatic system (the part of your body that helps to process and clear waste products) in different ways will help doctors understand more about lymphedema (excess fluid after lymph nodes are removed) and help with prevention and management of lymphedema in patients with breast cancer.

Disease Sites: Breast

Phase: N/A

Investigator: Donahue, Manus

NCTID: NCT03760744

Protocol No: VICCBRE18156

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A Study to Compare Two Surgical Procedures in Individuals with BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Ovarian

This clinical trial studies how well two surgical procedures (bilateral salpingectomy and bilateral salpingo-oophorectomy) work in reducing the risk of ovarian cancer for individuals with BRCA1 mutations. Bilateral salpingectomy involves the surgical removal of fallopian tubes, and bilateral salpingo-oophorectomy involves the surgical removal of both the fallopian tubes and ovaries. This study may help doctors determine if the two surgical procedures are nearly the same for ovarian cancer risk reduction for women with BRCA1 mutations.

Disease Sites: Ovarian

Phase: N/A

Investigator: Brown, Alaina

NCTID: NCT04251052

Protocol No: NRGGYNCC008

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Improving Care after Inherited Cancer Testing (IMPACT) Study

Miscellaneous

This clinical trial investigates factors associated with access to genetic risk assessment, counseling, and testings services. The trial also seeks to refine and evaluate the effectiveness of online tools on improving cancer risk management practices and family communication of genetic test results.

Disease Sites: Miscellaneous

Phase: N/A

Investigator: Pal, Tuya

NCTID: NCT04763915

Protocol No: VICCSUPP2112

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