Clinical Trials Search at Vanderbilt-Ingram Cancer Center
A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Gurin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy
Bladder
Bladder
The purpose of this study is to evaluate the overall complete response (CR) rate in
participants treated with TAR-200 in combination with cetrelimab (Cohort 1), or TAR-200 alone
(Cohort 2), or cetrelimab alone (Cohort 3) with Carcinoma in Situ (CIS), with or without
concomitant high-grade Ta or T1 papillary disease; and disease-free survival (DFS) in
participants treated with TAR-200 alone with papillary disease only (Cohort 4).
participants treated with TAR-200 in combination with cetrelimab (Cohort 1), or TAR-200 alone
(Cohort 2), or cetrelimab alone (Cohort 3) with Carcinoma in Situ (CIS), with or without
concomitant high-grade Ta or T1 papillary disease; and disease-free survival (DFS) in
participants treated with TAR-200 alone with papillary disease only (Cohort 4).
Bladder
II
Luckenbaugh, Amy
NCT04640623
VICCURO2106