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Clinical Trials Search at Vanderbilt-Ingram Cancer Center



A Phase 1 / 2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of AMG 510 in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreak 100)

Multiple Cancer Types

Evaluate the safety and tolerability of AMG 510 in adult subjects with KRAS p.G12C mutant advanced solid tumors. Estimate the maximum tolerated dose (MTD) and / or a recommended phase 2 dose (RP2D) in adult subjects with KRAS p.G12C mutant advanced solid tumors.
Miscellaneous, Phase I
I/II
Iams, Wade
NCT03600883
VICCPHI18161

A Study of Duvelisib in Combination With Pembrolizumab in Head and Neck Cancer

Multiple Cancer Types

This study will assess the safety and preliminary efficacy of duvelisib in combination with pembrolizumab in subjects with recurrent or metastatic (R / M) head and neck squamous cell carcinoma (HNSCC).
Head/Neck, Phase I
I/II
Gibson, Mike
NCT04193293
VICCHNP19109

A Phase 1 Study of TJ011133 Administered Alone or in Combination with Pembrolizumab or Rituximab in Subjects with Relapsed/Refractory Advanced Solid Tumors and Lymphoma

Multiple Cancer Types

Miscellaneous, Phase I
I
Berlin, Jordan
NCT03934814
VICCPHI1944

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