Clinical Trials Search at Vanderbilt-Ingram Cancer Center

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Neratinib HER Mutation Basket Study

Multiple Cancer Types

This is an open-label, multicenter, multinational, Phase 2 basket study exploring the efficacy and safety of neratinib as monotherapy or in combination with other therapies in participants with HER (EGFR, HER2) mutation-positive solid tumors.

Disease Sites: Bladder, Colon, Esophageal, Gastric/Gastroesophageal, Neuro-Oncology, Ovarian, Urologic, Uterine

Phase: II

Investigator: Mayer, Ingrid

NCTID: NCT01953926

Protocol No: VICCMD1403

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A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors

Multiple Cancer Types

This is a Phase 1, open label, multi center, dose escalation and expansion, safety, tolerability, PK, and pharmacodynamics study of PF 06939999 in previously treated patients with advanced or metastatic cancer.

Disease Sites: Bladder, Cervical, Esophageal, Head/Neck, Lung, Non Small Cell, Phase I, Uterine

Phase: I

Investigator: Berlin, Jordan

NCTID: NCT03854227

Protocol No: VICCPHI1909

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