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Genome_Maintenance_Research_Program News

Vanderbilt’s Dr. W. Kimryn Rathmell to be appointed director of the National Cancer Institute Vanderbilts Dr. W. Kimryn Rathmell to be appointed director of the National Cancer Institute

Kimryn Rathmell MD PhD MMHC the Hugh Jackson Professor of Medicine and chair of the Department of Medicine at Vanderbilt University Medical Center will be appointed Director of the National Cancer Institute.

Friday, November 17th, 2023
Crowe, Osheroff honored by AAMC Crowe Osheroff honored by AAMC

Vanderbilts James E. Crowe Jr MD and Neil Osheroff PhD are among 12 individuals honored by the Association of American Medical Colleges during its 2023 Awards Recognition Event.

Monday, October 30th, 2023
Research Snapshot: DNA replication discovery opens pathways to understanding and treating cancer, aging and degenerative disease

An international collaboration led by biochemist David Cortez reached revelatory conclusions in exploration of how cells tolerate DNA damage and genome instability. Est. reading time: 2 mins.

Tuesday, May 23rd, 2023
Study explores new urinary tract infection treatment

Vanderbilt's Neil Osheroff, PhD, is part of an international research collaboration resulting in what is on track to be the first new antibiotic treatment for uncomplicated urinary tract infections in more than 20 years.

Thursday, February 23rd, 2023
Gene network for leukemia factor Gene network for leukemia factor

Transcription factors — proteins that regulate gene expression — play critical roles in cell fate decisions and are frequent targets of mutation in a variety of human cancers.

Thursday, February 4th, 2021
A protein that can melt tumors discovered at Vanderbilt A protein that can melt tumors discovered at Vanderbilt
For the second time, cancer researchers at Vanderbilt have discovered a protein that—when genetically manipulated to impede it from interacting with a gene responsible for cancer genesis—effectively melts tumors in days.
Wednesday, January 27th, 2021
Cortez named interim chair of the Department of Biochemistry; York named Impossible Foods chief science officer Cortez named interim chair of the Department of Biochemistry; York named Impossible Foods chief science officer
David Cortez, PhD, Richard N. Armstrong Professor of Innovation in Biochemistry and professor of biochemistry, has been named interim chair in the Department of Biochemistry beginning Jan. 1, 2021.
Tuesday, December 8th, 2020
dividing cell Understanding cell division
Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells.
Tuesday, November 19th, 2019
Kimryn Rathmell Rathmell receives 2019 Eugene P. Schonfeld Award
The Kidney Cancer Association is recognizing the research accomplishments and leadership achievements of W. Kimryn Rathmell, MD, PhD, with its top honor, the Eugene P. Schonfeld Award.
Wednesday, November 6th, 2019
3d DNA illustration Completing DNA synthesis
James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis.
Monday, October 21st, 2019
Kimryn Rathmell VICC’s Rathmell honored with Louisa Nelson Award
Kimryn Rathmell, MD, PhD, director of the Division of Hematology and Oncology, received an award that honors women who embody the achievement, vision and inspiration of the founder of a local distillery.
Thursday, October 3rd, 2019
dna repair illustration Team’s study reveals details of new DNA repair pathway
Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.
Friday, July 26th, 2019
Neil Osheroff International Association of Medical Science Educators honors Osheroff
Neil Osheroff, PhD, received the Distinguished Career Award for Excellence in Teaching and Educational Scholarship from the International Association of Medical Science Educators (IAMSE).
Thursday, July 11th, 2019
imaging scanner Potential probe for early ovarian cancer
Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme.
Saturday, June 29th, 2019
William Tansey Researchers putting the brakes on lethal childhood cancer

A recent study suggests that blocking the MYC protein could be “unexpectedly effective” in treating malignant rhabdoid tumor (MRT) is one of the most aggressive and lethal childhood cancers.

Friday, May 3rd, 2019
yin yang symbol The yin and yang of cell signaling

Changes in enzymes involved in lysophospholipid signaling can activate a pathway implicated in development of cancer, a recent study suggests.

Thursday, February 14th, 2019
antibodies monoclonal HDAC3 role in B-cell development

Histone deacetylases (HDACs) are enzymes that modulate gene expression and have important roles in development and disease. HDAC inhibitors are active against lymphoma, and understanding the roles of specific HDACs is important for further therapeutic development. Scott Hiebert, Ph.

Monday, August 7th, 2017
McDonald lab Metastatic pancreatic cancer ‘reprograms’ for malignancy
Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. It may be possible to reverse the malignant reprogramming to treat metastatic pancreatic cancer, […]
Thursday, January 19th, 2017
VICC investigators in spotlight at AACR conference VICC investigators in spotlight at AACR conference
A top Vanderbilt-Ingram Cancer Center (VICC) investigator recently met with Vice President Joe Biden regarding the National Cancer Moonshot Initiative, a major national program to identify, fund and accelerate the most promising research leading to cancer cures. Carlos L. Arteaga, M.
Thursday, May 19th, 2016