Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
Multiple Cancer Types
This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Chemotherapy drugs, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. The trial studies whether carboplatin or cisplatin is the preferred chemotherapy to use in treating metastatic standard risk germ cell tumors.
          
          
                      Germ Cell (Pediatrics), 
                      Gynecologic, 
                      Ovarian
                  
      
              
        
          
                    
  
              III
          
        
        
      
              
        
          
                    
  
              Borinstein, Scott
          
        
        
      
              
        
          
                    
  
              NCT03067181
          
        
        
      
              
        
          
                    
  
              COGAGCT1531
          
        
        
          Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours
                                                                                                                                                                                                                                                                                                
              
  
          
              Germ Cell (Pediatrics)
              
      
          
  
  Germ Cell (Pediatrics)
              The purpose of this study is to determine whether accelerated BEP chemotherapy is more effective than standard BEP chemotherapy in males with intermediate and poor-risk metastatic germ cell tumours.
          
          
                      Germ Cell (Pediatrics)
                  
      
              
        
          
                    
  
              III
          
        
        
      
              
        
          
                    
  
              Borinstein, Scott
          
        
        
      
              
        
          
                    
  
              NCT02582697
          
        
        
      
              
        
          
                    
  
              COGAGCT1532
          
        
        
           
             
            