Clinical Trials Search at Vanderbilt-Ingram Cancer Center
Nilotinib, Trametinib, and Dabrafenib for the Treatment of BRAF V600 Mutant Metastatic or Unresectable Melanoma
Multiple Cancer Types
This phase I trial is to find out the best dose, possible benefits and/or side effects of nilotinib given together with trametinib and dabrafenib in treating patients with BRAF V600 mutant melanoma that has spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). Nilotinib, trametinib, and dabrafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving nilotinib together with trametinib and dabrafenib may lower the chance of cancer growing or spreading.
Melanoma,
Phase I
I
Johnson, Douglas
NCT04903119
VICCMELP2274
A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma
Multiple Cancer Types
The purpose of this study is to evaluate MEDI5752 in combination with Lenvatinib (or
Axitinib), in subjects with advanced renal cell carcinoma.
Axitinib), in subjects with advanced renal cell carcinoma.
Kidney (Renal Cell),
Phase I
I
Rini, Brian
NCT04522323
VICCUROP2043
Intraoperative identification and stimulation of the ANSA cervicalis.
Head/Neck
Head/Neck
Head/Neck
N/A
Kent, David
VICCHN2291
Targeted Early Detection Program in Men at High Genetic Risk for Prostate Cancer Prostate Cancer Risk Clinic (PCRC) Study
Prostate
Prostate
Prostate
N/A
Tosoian, Jeffrey
VICCURO22121
Descriptive Study of Pain Syndrome in Survivors of Head and Neck Cancer
Head/Neck
Head/Neck
Head/Neck
N/A
Kohutek, Zachary
VICC-VDHAN23178
Prospective Observational Trial of a Biodegradable Hyaluronic Acid Spacer in Prostate Cancer Radiotherapy
Prostate
Prostate
Prostate
N/A
Kirschner, Austin
VICC-VDURO23220
Developing a Trustworthy Multilevel Intervention to Improve Equity in Lung Cancer Screening
Lung
Lung
Lung
N/A
Richmond, Jennifer
VICC-VDTHO23221
