Clinical Trials Search at Vanderbilt-Ingram Cancer Center
Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03)
Head/Neck
Head/Neck
A Phase 2 Study of Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With
Advanced Head and Neck Squamous Cell Carcinoma.
Advanced Head and Neck Squamous Cell Carcinoma.
Head/Neck
II
Choe, Jennifer
NCT04675294
VICCHN20127
A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors
Multiple Cancer Types
The goal of this clinical trial is to test a new drug plus standard treatment compared with
standard treatment alone in patients with advanced head and neck squamous cell carcinoma and
cholangiocarcinoma.
The main questions it aims to answer are:
- is the new drug plus standard treatment safe and tolerable
- is the new drug plus standard treatment more effective than standard treatment
standard treatment alone in patients with advanced head and neck squamous cell carcinoma and
cholangiocarcinoma.
The main questions it aims to answer are:
- is the new drug plus standard treatment safe and tolerable
- is the new drug plus standard treatment more effective than standard treatment
Gastrointestinal,
Head/Neck
II
Heumann, Thatcher
NCT05712356
VICC-DTMDT23185
A Study Evaluating an Advanced Pneumatic Compression Device Versus Usual Care for Treatment of Head and Neck Lymphedema
Head/Neck
Head/Neck
To compare the effectiveness of an APCD to Usual Care in the management of lymphedema and
fibrosis (LEF) in head and neck cancer (HNC) survivors.
fibrosis (LEF) in head and neck cancer (HNC) survivors.
Head/Neck
N/A
Murphy, Barbara
NCT04797390
VICCHN2111
Biomarker-Driven Radiation Therapy Dose Reduction after Transoral Robotic Surgery for the Treatment of HPV-Positive Oropharyngeal Cancer
Head/Neck
Head/Neck
This phase II trial tests whether reduced dose radiation therapy after transoral robotic surgery works in treating patients with human papillomavirus (HPV)-positive oropharyngeal cancer. HPV positive oropharyngeal cancer has a better prognosis than oropharyngeal cancer not caused by HPV. A standard of care treatment for HPV positive oropharyngeal cancer is transoral robotic surgery followed by radiation therapy. However, this treatment is associated with many long-term side effects including difficulty swallowing. Radiation therapy uses high energy rays to kill tumor cells and shrink tumors. Giving reduced dose radiation therapy after transoral robotic surgery may improve swallowing outcomes and quality of life compared to standard of care dose radiation therapy after transoral robotic surgery.
Head/Neck
II
Topf, Michael
NCT05387915
VICC-ITHAN23125
Head and Neck Tumor Tissue Repository and Clinical Database
Head/Neck
Head/Neck
Head/Neck
N/A
Rosenthal, Eben
NCT00898638
VICCHN0356
Cancer Patient Safety Learning Laboratory (CaPSLL): Preventing Clinical Deterioration in Outpatients
Multiple Cancer Types
Head/Neck,
Lung
N/A
Weinger, Matthew
VICCMD1998
Impact of DHT on Swallowing Physiology in HNCa Patients
Head/Neck
Head/Neck
Head/Neck
N/A
Topf, Michael
VICCHN2102
Intraoral 3D Scanning of Head and Neck Resection Beds: a Feasibility Study.
Head/Neck
Head/Neck
Head/Neck
N/A
Topf, Michael
VICCHN2259
Virtual 3D Scanning and Intraoperative Communication System and Video Library for Head and Neck Surgical Specimens.
Head/Neck
Head/Neck
Head/Neck
N/A
Topf, Michael
VICCHN2272