Clinical Trials Search at Vanderbilt-Ingram Cancer Center

Neuroblastoma Maintenance Therapy Trial

Multiple Cancer Types

Difluoromethylornithine (DFMO) will be used in an open label, single agent, multicenter,
study for patients with neuroblastoma in remission. In this study subjects will receive 730
Days of oral difluoromethylornithine (DFMO) at a dose of 750 mg/m2 250 mg/m2 BID (strata 1,
2, 3, and 4) OR 2500 mg/m2 BID (stratum 1B) on each day of study. This study will focus on
the use of DFMO in high risk neuroblastoma patients that are in remission as a strategy to
prevent recurrence.

Disease Sites: Endocrine, Neuroblastoma (Pediatrics), Neuroendocrine, Pediatrics

Phase: II

Investigator: Pastakia, Devang

NCTID: NCT02679144

Protocol No: VICCPED16157

REACH (Research, Education, Advocacy, Clinical Care and Health) for Survivorship Program: Long Term Effects for Survivors of Cancer

Multiple Cancer Types

Disease Sites: Miscellaneous, Pediatrics

Phase: N/A

Investigator: Esbenshade, Adam

NCTID:

Protocol No: VICCPED0710

Infectious Disease Outcomes in Pediatric Oncology Patients

Multiple Cancer Types

Disease Sites: Miscellaneous, Pediatrics

Phase: N/A

Investigator: Esbenshade, Adam

NCTID:

Protocol No: VICCPED14127

Ocular Tumor Tissue Acquisition to Study Biologic Correlates of Disease

Multiple Cancer Types

Disease Sites: Pediatrics, Retinoblastoma (Pediatrics)

Phase: N/A

Investigator: Daniels, Anthony

NCTID:

Protocol No: VICCPED16115

Developing Evidence-Based Criteria for Initiating Treatment for Neurofibromatosis Type 1 Associated Optic Pathway Glioma

Multiple Cancer Types

Disease Sites: Neuro-Oncology, Pediatrics

Phase: N/A

Investigator: Esbenshade, Adam

NCTID:

Protocol No: VICCPED17108

CAUSAL: Cohort to Augment the Understanding of Sarcoma Survivorship Across the Lifespan.

Multiple Cancer Types

Disease Sites: Pediatrics, Sarcoma

Phase: N/A

Investigator: Friedman, Debra

NCTID:

Protocol No: VICCPED2222

Blood based biomarkers for minimal residual disease detection in Pediatric Sarcomas

Multiple Cancer Types

Disease Sites: Pediatrics, Sarcoma

Phase: N/A

Investigator: Borinstein, Scott

NCTID:

Protocol No: VICCPED2160

Expanded Access to Trametinib for a child with Plexiform Neurofibroma in NF1

Pediatrics

Disease Sites: Pediatrics

Phase: N/A

Investigator: Esbenshade, Adam

NCTID:

Protocol No: VICCPED2251

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