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Clinical Trials Search at Vanderbilt-Ingram Cancer Center



Clinical Information and Biospecimen Collection from Patients with Recurrent or Stage IV Breast Cancer

Breast

This trial collects clinical information and tissue and blood samples from patients with breast cancer that has come back or is stage IV. Collecting clinical information and biospecimen samples to create a registry may help doctors better understand the mechanism of tumor spread and determine why people respond differently to specific cancer treatments.
Breast
N/A
Park, Ben
NCT03737695
VICCBRE1954

Neuroinflammation in Chronic Systemic Symptoms in Patients with Head and Neck Cancer

Head/Neck

This study investigates markers of neuroinflammation in chronic systemic symptoms (CSS) in patients with head and neck cancer. CSS includes fatigue, neurocognitive dysfunction, centralized pain, mood disorders, sleep disturbances, and hypothalamic dysfunction manifested as thermal discomfort or hyperhidrosis (excessive sweating). Knowledge gained from this study may contribute to improving treatments for patients with CSS.
Head/Neck
N/A
Schoenburg, Poppy
NCT04636723
VICCHN20100

Comparing Two Methods to Follow Patients with Pancreatic Cysts

Pancreatic

The purpose of this study is to compare the two approaches for monitoring pancreatic cysts. The study doctors want to compare more frequent monitoring vs less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.
Pancreatic
N/A
Tan, Marcus
NCT04239573
ECOGGIEA2185

Rapid On Site Evaluation of Pleural Touch Preparations in Diagnosing Malignant Pleural Effusion in Patients Undergoing Pleuroscopy

Lung

This trial studies how well rapid on site evaluation of pleural touch preparations works in diagnosing cancerous fluid in between the linings of the lungs (malignant pleural effusion) in patients undergoing a pleuroscopy. A type of laboratory testing called rapid on site evaluation of pleural touch preparations that uses pleural biopsy tissue samples collected during an already-scheduled pleuroscopy may be able to diagnose malignant pleural effusion.
Lung
N/A
Maldonado, Fabien
NCT03868579
VICCTHO1991

Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients with Prostate Cancer

Prostate

This phase II trial studies how well multiparametric magnetic resonance imaging (MRI) works in evaluating cancer stage and helping treatment planning in patients with prostate cancer. Multiparametric MRI may be useful for evaluating the type of cancer in finding aggressive disease.
Prostate
II
Planz, Virginia
NCT03697148
ECOGUROEA8171

Registry Study for Talimogene Laherparepvec

Melanoma

A Registry Study to Evaluate the Survival and Long-Term Safety of Subjects Who Previously Received Talimogene Laherparepvec in Amgen or BioVEX-Sponsored Clinical Trials
Melanoma
N/A
Johnson, Douglas
NCT02173171
VICCMEL14103

Screening Methods for Early Diagnosis of Lung Cancer in Current or Former Smokers

Multiple Cancer Types

This trial studies methods of detecting lung cancer at an earlier stage in current or former smokers with a special type of computed tomography (CT) scan and by testing genes and proteins in biospecimens (blood, urine, sputum, and tissue samples) collected at the time of bronchoscopy (examination of the airway). Analyzing these methods may provide an early detection of lung cancer in current or former smokers when it is more amenable to a cure.
Lung, Miscellaneous, Non Small Cell
N/A
Massion, Pierre
NCT01475500
VICCTHO1078

Observational Retrospective Cohort Study of Systemic Therapies for R / R DLBCL

Lymphoma

To compare the efficacy outcomes of the L-MIND cohort with the effectiveness in a matched patient population treated with systemic NCCN / ESMO guideline listed regimens administered in routine clinical care.
Lymphoma
N/A
Reddy, Nishitha
NCT04697160
VICCPCL2053

11C-Glutamine PET / CT for the Diagnosis of Lymphangioleiomyomatosis

Multiple Cancer Types

This phase I trial evaluates the use of 11C-glutamine PET / CT in diagnosing patients with lymphangioleiomyomatosis. Lymphangioleiomyomatosis (LAM) is a disease that affects the lungs and is associated with tumors of the kidney called angiomyolipomas (AMLs). PET imaging is potentially more sensitive than standard imaging methods such as magnetic resonance imaging (MRI) or x-ray computed tomography (CAT / CT) scanning. Diagnostic procedures, such as 11C-glutamine PET / CT, may help find and diagnose lymphangioleiomyomatosis and help measure a patient's response to earlier treatment. The purpose of this trial is to determine how well 11C-glutamine can detect the activity of lung disease and / or the activity of any AMLs and develop better ways to diagnose and monitor disease activity in patients with LAM, including the effect of therapies on LAM patients.
Lung, Phase I
I
Blackwell, Timothy
NCT04388371
VICCTHO20106

Navigation Endoscopy for the Diagnosis of Indeterminate Lung Nodules, VERITAS Study

Lung

This trial studies how well navigation endoscopy works in diagnosing indeterminate lung nodules. Navigation bronchoscopy is a procedure using technology designed to guide a flexible bronchoscope (a small tube with a camera) through the natural airway route (wind-pipe and bronchi) to access the nodule. Navigation bronchoscopy may be more accurate than the standard computed tomography (CT)-guided biopsy in diagnosing patients with indeterminate lung nodules.
Lung
N/A
Maldonado, Fabien
NCT04250194
VICCTHO19102

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