Clinical Trials Search at Vanderbilt-Ingram Cancer Center
Navigation Endoscopy for the Diagnosis of Indeterminate Lung Nodules, VERITAS Study
Lung
Lung
This trial studies how well navigation endoscopy works in diagnosing indeterminate lung nodules. Navigation bronchoscopy is a procedure using technology designed to guide a flexible bronchoscope (a small tube with a camera) through the natural airway route (wind-pipe and bronchi) to access the nodule. Navigation bronchoscopy may be more accurate than the standard computed tomography (CT)-guided biopsy in diagnosing patients with indeterminate lung nodules.
Lung
N/A
Maldonado, Fabien
NCT04250194
VICCTHO19102
Disposable Perfusion Phantom for Accurate DCE-MRI Measurement of Pancreatic Cancer Therapy Response
Pancreatic
Pancreatic
This trial tests the use of a disposable perfusion phantom (P4) to decrease errors in calculating the blood flow of a tissue with DCE-MRI. DCE-MRI is used calculate blood flow of various tissues including tumors. Blood flow often serves as a critical indicator showing a disease status. For example, a pancreatic tumor has typically low blood flow, so it can be used as an indicator to identify the presence of a pancreatic tumor. In addition, an effective therapy may result in the increase of blood flow in a pancreatic tumor during the early period of treatment. Therefore, DCE-MRI may be used to determine whether the undergoing therapy is effective or not by measuring the change of blood flow in the pancreatic tumor and may help doctors decide whether to continue the therapy or try a different one. Unfortunately, the measurement of blood flow using DCE-MRI is not accurate. The use of an artificial tissue, named "phantom" or P4, together with a patient may help to reduce errors in DCE-MRI because errors will affect the images of both the patient and the phantom. Because it is known how the blood flow of the phantom appears when no errors are present, the phantom may be used to detect what kinds of errors are present in the image, how many errors are present in the image, and how to remove errors from the image.
Pancreatic
N/A
Xu, Junzhong
NCT04588025
VICCGI2099
A Phase 2 Study of ALX148 in Combination with Pembrolizumab and Chemotherapy in Patients with Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-04)
Head/Neck
Head/Neck
Head/Neck
II
Gibson, Mike
NCT04675333
VICCHN2110
The COVID-19 and Cancer Consortium (CCC19) Registry
Miscellaneous
Miscellaneous
Miscellaneous
N/A
Warner, Jeremy
NCT04354701
VICCMD2032
Molecular Predictors of Lung Cancer Behavior. (SPORE)
Multiple Cancer Types
Lung,
Non Small Cell,
Small Cell
N/A
Maldonado, Fabien
NCT00898313
VICCTHO0398
Islet Cell and ST2 Axis Dysregulation in Post-Transplant Diabetes Mellitus
Not Available
N/A
Engelhardt, Brian
NCT03415139
VICCCTT1836
Inherited CAncer REgistry (ICARE) Initiative
Miscellaneous
Miscellaneous
Miscellaneous
N/A
Pal, Tuya
NCT03231891
VICCMD1712
A Phase I/Ib Open-Label, Multi-Center, Dose-Escalation Study to Investigate the
Safety, Pharmacokinetics and Preliminary Efficacy of Intravenous NBF-006 in
Patients with Non-Small Cell Lung, Pancreatic, or Colorectal Cancer Followed by a
Dose Expansion Study in Patients with KRAS-Mutated Non-Small Cell Lung Cancer
Multiple Cancer Types
Lung,
Non Small Cell,
Phase I
I
Iams, Wade
NCT03819387
VICCTHOP2149
Molecular Fingerprinting of Lung Cancer (SPORE)
Multiple Cancer Types
Lung,
Non Small Cell
N/A
Grogan, Eric
NCT00897117
VICCTHO0136
