Clinical Trials Search at Vanderbilt-Ingram Cancer Center

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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Multiple Cancer Types

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics, and
pharmacodynamics of INCB099318 in select solid tumors.

Disease Sites: Miscellaneous, Phase I

Phase: I

Investigator: Berlin, Jordan

NCTID: NCT04272034

Protocol No: VICCPHI2136

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Hematologic

This study is an access and distribution protocol for unlicensed cryopreserved cord blood
units (CBUs) in pediatric and adult patients with hematologic malignancies and other
indications.

Disease Sites: Hematologic

Phase: N/A

Investigator: Kassim, Adetola

NCTID: NCT01351545

Protocol No: VICCCTT1158

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Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer, CISTO Study

Bladder

This study compares therapy within the bladder (intravesical therapy) and surgery as treatment options for patients with bladder cancer. Bladder cancer is the fifth most common cancer in the United States, but not enough research is available to help patients decide between the two most common treatments: medical therapies or bladder removal. The purpose of this study is to compare how the two treatments affect patient clinical outcomes and patient and caregiver experiences. This study may help researchers improve the decision-making process about bladder cancer treatments for patients and their caregivers.

Disease Sites: Bladder

Phase: N/A

Investigator: Scarpato, Kristen

NCTID: NCT03933826

Protocol No: VICCURO19105

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CIBMTR Research Database

Hematologic

The primary purpose of the Research Database is to have a comprehensive source of
observational data that can be used to study HSC transplantation and cellular therapies.

A secondary purpose of the Research Database is to have a comprehensive source of data to
study marrow toxic injuries.

Objectives:

To learn more about what makes stem cell transplants and cellular therapies work well such
as:

- Determine how well recipients recover from their transplants or cellular therapy;

- Determine how recovery after a transplant or cellular therapy can be improved;

- Determine how a donor's or recipient's genetics impact recipient recovery after a
transplant or cellular therapy;

- Determine how access to transplant or cellular therapy for different groups of patients
can be improved;

- Determine how well donors recover from the collection procedures.

Disease Sites: Hematologic

Phase: N/A

Investigator: Kassim, Adetola

NCTID: NCT01166009

Protocol No: VICCCTT1110

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Evaluating Sexual Function in Women Undergoing a Radical Cystectomy for Bladder Cancer

Bladder

This study evaluates the general physical, emotional, and sexual function in women undergoing a radical cystectomy for bladder cancer. A radical cystectomy is a surgical procedure that involves the removal of the bladder, uterus, ovaries, fallopian tubes, and part of the vagina. This may affect sexual function in women. This study seeks to understand how radical cystectomy alters sexual function and well-being, and what factors may affect this change.

Disease Sites: Bladder

Phase: N/A

Investigator: Luckenbaugh, Amy

NCTID: NCT05399004

Protocol No: VICCURO2075

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