Clinical Trials Search at Vanderbilt-Ingram Cancer Center

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Afatinib and Necitumumab in Treating Patients with EGFR Mutation Positive Advanced or Metastatic Non-small Cell Lung Cancer

Multiple Cancer Types

This phase I trial studies the side effects and best dose of afatinib and necitumumab and to see how well they work in treating patients with EGFR mutation positive non-small cell lung cancer that has spread to other places in the body. Afatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as necitumumab, may interfere with the ability of tumor cells to grow and spread. Giving afatinib and necitumumab may work better in treating patients with EGFR mutation positive non-small cell lung cancer.

Disease Sites: Lung, Non Small Cell

Phase: I

Investigator: Horn, Leora

NCTID: NCT03054038

Protocol No: VICCTHO1684

Study to Evaluate Eflornithine + Lomustine vs Lomustine in Recurrent Anaplastic Astrocytoma (AA) Patients

The purpose of this study is to compare the efficacy and safety of eflornithine in combination with lomustine, compared to lomustine taken alone, in treating patients whose anaplastic astrocytoma has recurred / progressed after radiation and temozolomide chemotherapy.

Disease Sites: Not Available

Phase: III

Investigator: Moots, Paul

NCTID: NCT02796261

Protocol No: VICCNEU1670

Neuroblastoma Biology Studies

Multiple Cancer Types

Disease Sites: Neuroblastoma (Pediatrics), Pediatrics

Phase: N/A

Investigator: Pastakia, Devang

NCTID: NCT00256763

Protocol No: CCGANBL00B1

Head and Neck Tumor Tissue Repository and Clinical Database

Head/Neck

Disease Sites: Head/Neck

Phase: N/A

Investigator: Kim, Young Jun

NCTID: NCT00898638

Protocol No: VICCHN0356

Melanoma, Pigmented Lesion and Cutaneous Malignancy Tissue and Bio-Specimen Repository

Multiple Cancer Types

Disease Sites: Dermatologic, Melanoma

Phase: N/A

Investigator: Kauffmann, Rondi

NCTID:

Protocol No: VICCMEL0287

Novel Gastrointestinal Cancer Markers in Tissue and Biofluids

Gastrointestinal

Disease Sites: Gastrointestinal

Phase: N/A

Investigator: Beauchamp, Robert

NCTID: NCT00899626

Protocol No: VICCGI0283

Repository for National Donor Program (NMDP) Research Blood Samples.

Hematologic

Disease Sites: Hematologic

Phase: N/A

Investigator: Kassim, Adetola

NCTID:

Protocol No: NMDPBMT0346

Donating Tissues for Research

Miscellaneous

Disease Sites: Miscellaneous

Phase: N/A

Investigator: Washington, Mary Kay

NCTID:

Protocol No: VICCBIO0478

Key Adverse Events after Childhood Cancer

Multiple Cancer Types

Disease Sites: Miscellaneous, Pediatric Leukemia, Pediatrics

Phase: N/A

Investigator: Friedman, Debra

NCTID: NCT00082745

Protocol No: COGALTE03N1

REACH (Research, Education, Advocacy, Clinical Care and Health) for Survivorship Program: Long Term Effects for Survivors of Cancer

Multiple Cancer Types

Disease Sites: Miscellaneous, Pediatrics

Phase: N/A

Investigator: Esbenshade, Adam

NCTID:

Protocol No: VICCPED0710

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